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2022

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Full-Text Articles in Kinesiology

Effects Of Exercise On Parkinson's Symptom Relief, Brooke Burnett May 2022

Effects Of Exercise On Parkinson's Symptom Relief, Brooke Burnett

The Eleanor Mann School of Nursing Undergraduate Honors Theses

In this review of twenty research articles, the effects of moderate exercise therapy on the symptoms of Parkinson’s Disease will be explored. Appropriate literature was located using the research question, “In older adults with a Parkinson’s Disease Diagnosis, how does moderate exercise influence the symptoms of this disease?” Twenty peer-reviewed research articles were examined for the impact of different forms of exercise on various symptoms associated with Parkinson’s. Nineteen of the articles reviewed provide substantial evidence in support of exercise therapy as a treatment option for people with Parkinson’s, and one of the articles found inconclusive evidence neither in support …


Relationship Of Eccentric Strength And Forward Perturbation Restabilization After Foot Contact, Leandra K. Ashworth May 2022

Relationship Of Eccentric Strength And Forward Perturbation Restabilization After Foot Contact, Leandra K. Ashworth

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Background: Forward falls are the most common fall direction and pose safety concerns for adults. To prevent forward falls, compensatory steps, and change-in-support reactions (e.g., foot contact) are critical for restabilizing center of mass after unpredictable, balance disturbances. Multi-joint, lower limb eccentric and isometric strength may provide additional insight on foot contact responses after a forward, temporally unpredictable perturbation. Multi-joint, eccentric muscular contractions have been found to result in significant neuromuscular adaptations (e.g., hypertrophy and muscular strength) and have higher retention capabilities than concentric contractions. Due to the importance of muscular strength in balance recovery, eccentric muscular strength could provide …


Effects Of Branched Chain Amino Acid Supplementation On Post-Exercise Muscle Recovery And Muscle Growth, Kyla N. Marquez May 2022

Effects Of Branched Chain Amino Acid Supplementation On Post-Exercise Muscle Recovery And Muscle Growth, Kyla N. Marquez

Honors Projects

BCAA supplements are composed of three main essential amino acids, including leucine, isoleucine, and valine. The concept of BCAA supplementation comes from the fact that essential amino acids cannot be made by the body and must be derived from food and diet, as amino acids are the building blocks of proteins and muscle. Thus, by increasing intake of these essential amino acids, BCAAs are believed to reduce the effects of exercise-induced muscle damage (EIMD) by increasing availability of these important compounds. However, BCAAs are not approved by the Food & Drug Administration (FDA) as the FDA does not regulate dietary …


The Role Of Dynamic Gaze Fixations In Human Postural Control, Grace Balsam May 2022

The Role Of Dynamic Gaze Fixations In Human Postural Control, Grace Balsam

Health, Human Performance and Recreation Undergraduate Honors Theses

Background: The human postural control system, which controls balance, is constantly taking in sensory input to help maintain balance while allowing one to pay attention to their daily activities. Using visual search tasks, we will be able to understand information relevant to how changes in visual input affects one’s postural control representative of a more real-life scenario. Purpose: With the help eye tracking technology, this study assesses changes in postural control during various visual conditions. Postural control will be measured during such tasks to analyze how it compares to a simple, quiet balancing task. Following Bonnet and Baudry’s …


Self-Rated Function And Delayed Onset Muscle Soreness (Doms) Responses To 6-Week Supplementation With Waters With Anti-Inflammatory Capabilities (Wac), Kristin Garner May 2022

Self-Rated Function And Delayed Onset Muscle Soreness (Doms) Responses To 6-Week Supplementation With Waters With Anti-Inflammatory Capabilities (Wac), Kristin Garner

Health, Human Performance and Recreation Undergraduate Honors Theses

Introduction: Researchers have examined the effects of sedentary lifestyles on diminished health outcomes and are pleading individuals to take on a more active lifestyle to prevent these. However, initial efforts to exercise are often dampened by delayed onset muscle soreness (DOMS) and muscle fatigue. This can greatly reduce exercise adherence, making it difficult for individuals to overcome this temporary discomfort. Background: Research has extensively evaluated nonsteroidal anti-inflammatory drugs (NSAIDs) and fruits as anti-inflammatory supplementation to treat DOMS. Berry-derived essences are more highly concentrated in anti-inflammatory substances than regular fruit juices, but there is minimal research on their effects on exercise …


The Validity Of The Vmaxpro During Countermovement Jump And Back Squat Performance, Hunter Haynes May 2022

The Validity Of The Vmaxpro During Countermovement Jump And Back Squat Performance, Hunter Haynes

Master's Theses

Background: Advances in technology have resulted in an increase in the utilization of velocity-based training in the strength and conditioning field while utilization of inertia measurement units (IMUs) shows promise. Methods: Recreationally trained participants (N=25, 28.3 ± 2.9 years) were recruited to determine the validity of the VmaxPro device for measuring performance variables in the back squat and countermovement jump (CMJ) against a gold standard force plate. Squat variables assessed included mean concentric velocity (MCV), mean concentric power (MCP), depth, and duration while CMJ variables assessed included MCV, MCP, depth, duration, and jump height. Squat variables were assessed across 3 …


Examining The Effects Of Oral Contraceptive Use On Thermoregulation, Whitley C. Atkins May 2022

Examining The Effects Of Oral Contraceptive Use On Thermoregulation, Whitley C. Atkins

Graduate Theses and Dissertations

Purpose: The purpose of this investigation was to evaluate the effects of combined (estradiol and progestin) monophasic oral contraceptive pill (OCP) use on thermoregulation. Further, we sought to evaluate OCP use on acute rehydration post-exercise in the heat using recommended rehydration guidelines. Methods: Twelve healthy, aerobically trained (VO2peak = 47.8 ± 4.7 mL/kg/min), long term female oral contraceptive users completed a familiarization trial and two experimental days separated by ≥ 7 days. The two experimental trials were identical except for the hormone dosing phase. One trial was completed during the third week of active pill dosing (ACT) and one during …


Effects Of An 8-Week Resisted Sprint Training Program On Ice Skating Speed, Acceleration, And Measures Of Athletic Performance In Male Youth Ice Hockey Players, Martin Sterling Diettze-Hermosa May 2022

Effects Of An 8-Week Resisted Sprint Training Program On Ice Skating Speed, Acceleration, And Measures Of Athletic Performance In Male Youth Ice Hockey Players, Martin Sterling Diettze-Hermosa

Open Access Theses & Dissertations

Recently, resisted sprint training has become a widely utilized modality to increase the running speed and acceleration of athletes necessitating fast movements for successful sport performance. However, ice hockey is a sport that requires speed and acceleration despite not being running-based. Yet, the impact of a longitudinal resisted sprint training intervention with known resistance on ice skating remains uninvestigated. Ice hockey players engage in both on-ice and overground training. It is presently unknown whether an on-ice resisted sprint training program is superior to an overground resisted sprint training program to increase measures of ice hockey performance. Thus, purposes of this …


The Mobility And Cognitive Mechanisms Involved In Altering Gait Speed In Children With Autism Spectrum Disorder, Alyssa Olivas May 2022

The Mobility And Cognitive Mechanisms Involved In Altering Gait Speed In Children With Autism Spectrum Disorder, Alyssa Olivas

Open Access Theses & Dissertations

Autism is a socio-behavioral disorder, and diagnoses are conducted through behavioral screening instruments. Recent research suggests motor deficits may be a core symptom of the disorder, as children with autism present with deficits in motor development, locomotor skills, and postural instability. In addition, children with autism often have affected, executive function, attention, and perception cognitive domains. Different gait speeds have been used to examine gait adaptations in other clinical populations. Additionally, individuals with decreased cognitive abilities have demonstrated difficulties in modulating their walking speed. There is limited research on mechanisms children with autism use to alter their gait speed, or …


The Relationship Of Strength, Mobility, And Performance Variables On Throwing Speed In Baseball Catchers, Caleigh D. Hall May 2022

The Relationship Of Strength, Mobility, And Performance Variables On Throwing Speed In Baseball Catchers, Caleigh D. Hall

Human Movement Studies & Special Education Theses & Dissertations

Baseball is a popular sport worldwide and has thus garnered significant research focus, predominately of pitchers and hitters. However, research involving catchers is scant despite their major influence and consistent presence throughout a game. Therefore, the purpose of this study was to determine the relationship of lower body strength and mobility and performance with throwing speed in baseball catchers. We hypothesized that strength and mobility would have a positive relationship with ball speed, peak power generated while rising out of the squat position would be positively related to ball speed, shorter ascent time would be inversely related to ball speed, …


Inflammaging: Inflammatory Biomarkers Associated With Nutrition, Metabolism And Muscle Tissue Oxygenation Relative To Sarcopenic Status In Older Adults, Marni Elise Shoemaker May 2022

Inflammaging: Inflammatory Biomarkers Associated With Nutrition, Metabolism And Muscle Tissue Oxygenation Relative To Sarcopenic Status In Older Adults, Marni Elise Shoemaker

Open Access Theses & Dissertations

The purpose of this study is to examine if we can differentiate inflammaging between sarcopenic and non-sarcopenic older adults by exploring if there are differences between biomarkers of inflammation and nutritional status in older adults with distinct differences in skeletal muscle mass, strength, and function, metabolic flexibility, and muscle tissue oxygenation. Twenty-one non-sarcopenic (mean±standard deviation, age = 73.1±6.2 yrs, n=5 males, n=5 females) and sarcopenic (age = 81.2±10.5 yrs, n=6 males, n=5 females) were categorized based on muscle mass and strength criteria according to the European Working Group on Sarcopenia in Older People. Body composition, handgrip and leg extension strength, …


Content Analysis Of Public Instagram Posts About Pelvic Floor Disorders And Pelvic Floor Muscle Training In Pregnancy, Lauren R. Rudin, Molly E. Waring May 2022

Content Analysis Of Public Instagram Posts About Pelvic Floor Disorders And Pelvic Floor Muscle Training In Pregnancy, Lauren R. Rudin, Molly E. Waring

Honors Scholar Theses

Objective: To analyze the content of public Instagram posts and describe the discussion of pelvic floor disorders (PFDs) and pelvic floor muscle training (PFMT)/pelvic floor physical therapy (PFPT) in pregnancy. Methods: Public Instagram accounts based in the U.S. with posts within the past 7 days focused on pregnancy were included. We analyzed English posts related to pelvic floor health, PFDs or PFMT. We categorized accounts by user type, health-related expertise, business endorsement, and influencer status. We categorized posts by content (informative, recommendation, sharing experience, meme, advertisement), context (informative, preventive, interventive), and terminology (scientific, lay). We used chi-squared tests to compare …


The Progress Of Power: A Narrative Review Of The Practical Progression Of Running Power Assessment And Application, Andrew David Fields May 2022

The Progress Of Power: A Narrative Review Of The Practical Progression Of Running Power Assessment And Application, Andrew David Fields

Masters Theses

Power has revolutionized endurance athletics. Power is a function of the amount of force produced in a certain amount of time. Utilized correctly, it can be an effective metric of effort during endurance activities. Cycling saw the first fruits of this metric in the 1980s and 1990s with Tour de France athletes and has continued to provide immense benefits to cyclists. Power when applied to running, however, has seen a much slower progression toward effective use. Various attempts in the 1970s and 80s to use calculations to express running power as a function of multiple different kinematic variables proved futile. …


Postprandial Hemodynamics In Hispanics With And Without A Family History Of Type 2 Diabetes, Gabriel Alejandro Figueroa May 2022

Postprandial Hemodynamics In Hispanics With And Without A Family History Of Type 2 Diabetes, Gabriel Alejandro Figueroa

Theses and Dissertations

Hispanics of the Rio Grande Valley (RGV) have the highest rates of obesity and type 2 diabetes (T2D) in the country, conditions often associated with cardiovascular disease and increased mortality. This study investigated the physiological factors affecting postprandial hemodynamic responses differently between FH+ and FH- groups. Thirty-one healthy Hispanic individuals volunteered in this study. Overall, FH+ individuals had higher pressures at rest compared to FH-, However, these differences were not statistically significant. When controlling for blood chemistries such as blood glucose, cholesterol, lipoproteins, and triglycerides, family history appears to have no effect on fasted or postprandial hemodynamics and pulse wave …


Comparing Various Physiological System Adaptations Following 8 Weeks Of Resistance Training With Or Without Bfr In Older Males, Ricardo Parra May 2022

Comparing Various Physiological System Adaptations Following 8 Weeks Of Resistance Training With Or Without Bfr In Older Males, Ricardo Parra

Theses and Dissertations

PURPOSE: The purpose of this study was to compare the effects of 8 weeks of resistance exercise training with and without BFR on: 1), arterial elasticity and hemodynamics (e.g., blood pressure and resting heart rate), 2) muscular force production (e.g., maximal voluntary contraction, force production, electromyography, and estimated one-repetition maximum) in males between the 50 to 70 years of age.

RESULTS: Significant condition difference for reflection magnitude occurred in BFR group (p < 0.05). Significant time*condition effect occurred in Leg Press 1RM, Leg Extension 1RM, Leg Curl 1RM, Chest Press 1RM, and Shoulder Press 1RM (p < 0.05). Significant condition* time interaction occurred for Isokinetic Leg Extension Test (60°/s) (p < 0.05). A significant time*condition interaction occurred during Maximal Voluntary Contraction (MVC) – Root Mean Square for both vastus medialis and vastus lateralis (p < 0.05). A significant time main effect occurred in the BFR group for the amplitude mean of the MVC in the vastus medialis and vastus lateralis (p < 0.05). A significant time main effect occurred for median frequency of the MVC (p < 0.05). A significant difference in Estimated Visceral Adipose Tissue occurred in the BFR group (p < 0.05). A significant condition*time interaction occurred in arm fat percentage (p < 0.05). The BFR group had significantly less fat tissue (%) in the left arm (p < 0.01) and in the right arm (p = 0.04). A significant time*main effect occurred in the total lean tissue for the left side of the body (p = 0.04).

CONCLUSION: Using BFR resistance training at a low intensity can achieve similar adaptations seen at high intensities while reducing the risk of injury that comes with heavier loads.


Direction Of Attentional Focus In Prosthetic Training: Current Practice And Potential For Improving Motor Learning In Individuals With Lower Limb Loss, Alexander Bonczyk, Maria Katrina Tillada Dimapilis, Sarah Partridge, Samantha Ruiz May 2022

Direction Of Attentional Focus In Prosthetic Training: Current Practice And Potential For Improving Motor Learning In Individuals With Lower Limb Loss, Alexander Bonczyk, Maria Katrina Tillada Dimapilis, Sarah Partridge, Samantha Ruiz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: Adopting an external focus of attention has been shown to benefit motor performance and learning. However, the potential of optimizing attentional focus for improving prosthetic motor skills in lower limb prosthesis (LLP) users has not been examined. In this study, we investigated the frequency and direction of attentional focus embedded in the verbal instructions in a clinical prosthetic training setting.

Methods: Twenty-one adult LLP users (8 female, 13 male; 85% at K3 level; mean age=50.5) were recruited from prosthetic clinics in the Southern Nevada region. Verbal interactions between LLP users and their prosthetists (mean experience=10 years, range=4-21 years) during …


Effects Of A Remote Exercise Intervention On Aerobic Endurance In Individuals With Down Syndrome, Andrew Murata, Elena Wolf, Jonathan Crimm, Benjamin Lee May 2022

Effects Of A Remote Exercise Intervention On Aerobic Endurance In Individuals With Down Syndrome, Andrew Murata, Elena Wolf, Jonathan Crimm, Benjamin Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose: Down syndrome (Ds) or Trisomy 21 is a common genetic birth condition, and those with Ds typically display decreased cardiorespiratory fitness compared to those without Ds, potentially leading to an increased risk for cardiovascular conditions and mortality. Low cardiorespiratory fitness is partially caused by low physical activity levels in this population. The COVID-19 pandemic caused community-based activity programs to shut down, as individuals with Ds are at increased risk for COVID-19 hospitalization and death. Thus, it was vital to explore alternatives of in-person exercise during the pandemic. The purpose of this study was to investigate the effects of a …


Diurnal Regulation Of Exercise-Induced Myocardial Signaling And Transcription, Charli Aguilar May 2022

Diurnal Regulation Of Exercise-Induced Myocardial Signaling And Transcription, Charli Aguilar

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Exercise is well known for its many benefits on the body and most notably the heart. Recent emphasis, and significant resources, have been dedicated to elucidating the molecular mechanisms through which exercise exerts its pluripotent beneficial effects on health and the prevention of disease. A continuous evolution in this field has sought to modulate and optimize exercise in various ways to maximize the benefits. In recent years, a growing appreciation for the impact of circadian rhythms has gained traction and their influence on many essential biological functions have been integrated into exercise physiology (i.e. - chrono-exercise), as well as …


The Effect Of Attachment Design And Aligner Material On The Efficiency Of Maxillary Canine Distalization In Premolar Extraction Cases, Najem Anbari May 2022

The Effect Of Attachment Design And Aligner Material On The Efficiency Of Maxillary Canine Distalization In Premolar Extraction Cases, Najem Anbari

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Clear Aligner Therapy (CAT) is regarded as a popular esthetic alternative to conventional orthodontic treatment with fixed labial appliances. The mechanism of action, force delivery and limitation of this treatment modality remain largely unknown despite its popularity, the high demand and the relatively long evolutionary track of clear aligners. There are only few studies that addressed the elements that influence the efficiency of clear aligners, namely, the attachment design and aligner materials. It is widely believed that clear aligners are not suitable for extraction cases due to their lack of control over the root movement.

Objectives: This in vitro …


The Effect Of One Night Of Sleep Fragmentation On Aerobic Exercise Performance, Tara L. Thompson May 2022

The Effect Of One Night Of Sleep Fragmentation On Aerobic Exercise Performance, Tara L. Thompson

Senior Honors Projects, 2020-current

Purpose: People can experience sleep fragmentation for many reasons. The negative effect this has on a person’s daytime function and sleepiness has already been studied extensively, yet there is little on the effect it has on a person’s aerobic athletic performance. Many athletes experience frequent wake-ups in the middle of the night, due to nerves and other factors, which could potentially affect their performance.

Methods: For each of the eight subjects, testing began with a VO2max test and a familiarization trial. Following this, subject’s then participated in two experimental trials, where they were randomly assigned either a night of sleep …


Implementing An Exercise Referral Scheme For Promoting Physical Activity In University Mental Health Care, Bryce Daniels May 2022

Implementing An Exercise Referral Scheme For Promoting Physical Activity In University Mental Health Care, Bryce Daniels

Graduate Theses and Dissertations

Introduction. Mental health symptoms and conditions are prevalent and increasing on college campuses with anxiety and depression having the highest increases in prevalence. Many college students are also physically inactive which is problematic as physical activity benefits mental health. Exercise referral schemes (ERS) can promote physical activity, though no studies have investigated the implementation of an ERS within a college counseling center. Purpose. The purpose of this dissertation was to investigate the implementation of an ERS for promoting physical activity in university mental health care. Methods. Study 1 used a qualitative descriptive design of 14 certified counselors to explore perceptions …


Predictors Of Peak Elbow Valgus Torque In Collegiate Baseball Pitchers, Adam Richard Nebel May 2022

Predictors Of Peak Elbow Valgus Torque In Collegiate Baseball Pitchers, Adam Richard Nebel

Graduate Theses and Dissertations

Context: The incidence of UCL tears in baseball is at an all-time high. ATs are in the position to identify those at risk and potentially prevent injury to the UCL. In baseball, research has associated elbow valgus torque as a potential predictor of injury risk. However, markerless analysis has not assessed possible predictors of injury to the UCL in baseball players. Objective: Identify the kinematic factors that influence peak elbow valgus torque through the sequence of a fastball pitch. Design: Cross-sectional study. Setting: Field study performed in university’s pitching development center. Participants: Division 1 collegiate baseball pitchers (N=21; 17RHP, 4LHP; …


2-Day Vs. 4-Day Training Cessation Following A Step Taper In Competitive And Recreational Powerlifters, Benjamin Burke May 2022

2-Day Vs. 4-Day Training Cessation Following A Step Taper In Competitive And Recreational Powerlifters, Benjamin Burke

Electronic Theses and Dissertations

The purpose of this study was to compare differences in maximal strength, perceived recovery and stress state, and body composition alterations in powerlifters undergoing a 2-day or 4-day period of training cessation following a step taper. Ten participants completed a 6-week powerlifting specific training protocol. Body composition, perceived recovery and stress state, and maximal strength in the back squat (BS), bench press (BP), and deadlift (DL) were assessed prior to the overreach week (week 5) and either 2-days or 4-days after the taper. Alpha criterion was set at p≤0.05. There were statistically significant increases in BP (pp=0.03) …


The Effects Of A Telehealth Exercise Intervention On Balance In Adults With Down Syndrome, Mark Barton, Kristina Guerrero, Andrew Martinez, Alexandria Umagat May 2022

The Effects Of A Telehealth Exercise Intervention On Balance In Adults With Down Syndrome, Mark Barton, Kristina Guerrero, Andrew Martinez, Alexandria Umagat

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: People with Down syndrome (Ds) often present with balance deficits, which compromise their safety during daily activity. While evidence shows that exercise can improve balance in the Ds population, it is unclear if a telehealth method will elicit similar benefits. We aimed to examine the effects of a virtual exercise program on balance in adults with Ds.

Methods: Twenty participants completed a 12-week telehealth exercise program based on the Mann Method. Balance testing took place before and after the intervention, which included: Timed Up and Go (TUG), Modified Clinical Test of Sensory Interaction in Balance (MCTSIB), Frailty and Injuries: …


Sight Deprivation And Metabolic Effects During The Ymca Bench Press Test, Kyle Cruz May 2022

Sight Deprivation And Metabolic Effects During The Ymca Bench Press Test, Kyle Cruz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Several studies have investigated the effect of sensory deprivation, particularly sight. However, very few have demonstrated the impact of sight deprivation while exercising to cadence blindfolded. This study aimed to determine exercise performance during a common muscular endurance evaluation, the YMCA Bench Press Test (YBPT), while blindfolded compared to a sighted condition. Twenty-five healthy participants (11 male, 14 female, 168 ± 7.7cm, 68 ± 11.7kg, 23 ± 7.5% fat mass) were recruited from the University of Nevada, Las Vegas student populations and communities. After a YBPT familiarization session, participants completed testing in a counterbalanced order, following the same procedures. A …


Investigation Of Swimming Physiology And Swimming Kinematics While Wearing Different Triathlon Wetsuit Styles At Submaximal Front Crawl Swimming In Recreational Population, Boram Lim May 2022

Investigation Of Swimming Physiology And Swimming Kinematics While Wearing Different Triathlon Wetsuit Styles At Submaximal Front Crawl Swimming In Recreational Population, Boram Lim

UNLV Theses, Dissertations, Professional Papers, and Capstones

Triathlon wetsuits are commonly used due to the potential benefits in swimming performance and thermoregulation. Triathletes may select different wetsuit styles depending on many factors such as temperature regulation, swimming technique, body type, and training purpose. However, there is a lack of empirical evidence for how different wetsuit styles affect physiological responses and swimming kinematics during submaximal swimming intensity. Therefore, this studyaimed to investigate the physiological responses and swimming kinematics during submaximal intensity front crawl swimming while wearing different wetsuit styles. Fourteen participants (n=6 male, n=8 female; all recreational triathletes or swimmers) completed a swimming graded exercise test (GXT) wearing …


Attentional Focus And The Development Of Skilled Performance, Harjiv Singh May 2022

Attentional Focus And The Development Of Skilled Performance, Harjiv Singh

UNLV Theses, Dissertations, Professional Papers, and Capstones

A central question in the development of skilled movement is: how a performer should focus their attention while preparing for the execution of a motor skill? Considerable evidence has shown that directing attention towards an intended movement effect (i.e., external focus) results in performance benefits relative to focusing on body movements (i.e., internal focus). While most of the previous research has emphasized the effects of internal versus external foci, evidence also suggests that external foci located at greater distances from the body (distal foci) are more effective than external foci located in greater proximity to the body (proximal foci) and …


Time-Of-Day And Chronotype Dependent Effects Of Exercise On Migraine Load In People With Chronic Migraines: A Cross-Over Randomized Clinical Trial, Elias M. Malek May 2022

Time-Of-Day And Chronotype Dependent Effects Of Exercise On Migraine Load In People With Chronic Migraines: A Cross-Over Randomized Clinical Trial, Elias M. Malek

UNLV Theses, Dissertations, Professional Papers, and Capstones

Migraines are the most common cause of chronic pain. Effective, non-pharmacological strategies to reduce migraine load are needed. Exercise is an effective strategy, but it is unclear how exercise timing and temporal preference (chronotype) factors modulate the laudatory effects of exercise. Purpose: Determine the effects of; 1) time-of-day of exercise, and 2) exercise synchrony with one’s chronotype, on migraine load. Methods: Participants were 13 sedentary individuals with 8+ migraines/month (age = 30 ± 11 yrs, 167 ± 6 cm, 86 ± 28 kg). Participants were categorized into morning-/evening-types based on the Morning/Eveningness Questionnaire and instructed to complete 1 month of …


Predicting The Progression Of Diabetes Mellitus Using Dynamic Plantar Pressure Parameters, Mathew Sunil Varre May 2022

Predicting The Progression Of Diabetes Mellitus Using Dynamic Plantar Pressure Parameters, Mathew Sunil Varre

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Diabetic peripheral neuropathy is one of the common complications of type-2 diabetes mellitus (DM). Changes in the intrinsic plantar tissue coupled with repetitive mechanical loads and loss of sensation may lead to foot related complications (skin break down, ulcerations, and amputations) in persons with neuropathy if left untreated. The purpose of this dissertation was to stratify individuals with pre-diabetes, diabetes with and without neuropathy using dynamic plantar pressure parameters during walking, using machine learning algorithms.Methods: Plantar pressure data was collected from one hundred participants during walking with pressure measuring insoles fixed between the feet and thin socks. Simultaneously high-definition …


Growth Differentiation Factor 5 Is A Paracrine Regulator Of Sarcopenic Obesity, Landen W. Saling May 2022

Growth Differentiation Factor 5 Is A Paracrine Regulator Of Sarcopenic Obesity, Landen W. Saling

Graduate Theses and Dissertations

Sarcopenic obesity attributes to skeletal muscle loss more than sarcopenia and obesity alone. Individuals with SO suffer from the comorbidity of excess body fat and concurrent muscle mass loss due to aging. Growth differentiation factors (Gdfs) have never been recognized as playing a role in skeletal muscle maintenance in those with SO. Specifically, Gdf5, has been recognized as playing a part in Bone Morphogenic Protein signaling to activate protein synthesis and deactivate protein degradation via SMAD 1/5/8 and SMAD 4 complex. Using RNA sequencing, Gdf5 was identified as being significantly upregulated in SO mice. Purpose: To determine the cellular role …