Immunology and Infectious Disease Commons^™

Prevalence Of Cymothoidae (Isopoda) Infestation In Bigeye Scad (Selar Crumenophtalmus) From Batangas, Philippines, Tanya Faye S. Muji, Joaquin R. Sorreta, Janice A. Ragaza

Biology Faculty Publications

Cymothoid isopod research is relatively scarce in the Philippines, despite the local economic significance of bigeye scad as an inexpensive source of protein and other nutrients. Isopod parasitism has also been shown to have detrimental effects on their fish hosts. The current study aimed to define the host-parasite relationship between cymothoid isopod and bigeye scad by determining cymothoid isopod prevalence, intensity, and host-parasite length correlations in bigeye scad (Selar crumenophthalmus) hosts sourced from Batangas, Philippines. Fish samples were sampled from the Tagaytay City Market in Cavite, which sources fish directly from Batangas. Fish samples were immediately measured and …

Epigenetic Mechanisms Underlying Hiv-Infection Induced Susceptibility Of Cd4+ T Cells To Enhanced Activation-Induced Fasl Expression And Cell Death., Smita Ghare, Paula M. Chilton, Aakarsha V. Rao, Swati Joshi-Barve, Paula Peyrani, Andrea Reyes-Vega, Craig J. Mcclain, Kendall Bryant, Robert L. Cook, Mathew Freiberg, Shirish Barve

Faculty Scholarship

Background:

Chronic immune activation and CD4⁺ T cell depletion are significant pathogenic features of HIV infection. Expression of Fas ligand (FasL), a key mediator of activation-induced cell death in T cells, is elevated in people living with HIV-1 infection (PLWH). However, the epigenetic mechanisms underlying the enhanced induction of FasL expression in CD4⁺ T lymphocytes in PLWH are not completely elucidated. Hence, the current work examined the effect of HIV infection on FasL promoter-associated histone modifications and transcriptional regulation in CD4⁺ T lymphocytes in PLWH.

Method:

Flow cytometric analysis was performed to examine the Fas-FasL expression on …

Biodiversity Of The Coccidia (Apicomplexa: Conoidasida) In Vertebrates: What We Know, What We Do Not Know, And What Needs To Be Done, Donald W. Duszynski

Harold W. Manter Laboratory of Parasitology: Faculty and Staff Publications

Over the last two decades my colleagues and I have assembled the literature on a good percentage of most of the coccidians (Conoidasida) known, to date, to parasitise: Amphibia, four major lineages of Reptilia (Amphisbaenia, Chelonia, Crocodylia, Serpentes), and seven major orders in the Mammalia (Carnivora, Chiroptera, Lagomorpha, Insectivora, Marsupialia, Primates, Scandentia). These vertebrates, combined, comprise about 15,225 species; only about 899 (5.8%) of them have been surveyed for coccidia and 1,946 apicomplexan valid species names or other forms are recorded in the literature. Based on these compilations and other factors, I extrapolated that there yet may be an additional …

Global Distribution, Host Range And Prevalence Of Trypanosoma Vivax: A Systematic Review And Meta-Analysis, Eyerusalem Fetene, Samson Leta, Fikru Regassa, Philippe Büscher

Harold W. Manter Laboratory: Library Materials

Background

Trypanosomosis caused by Trypanosoma vivax is one of the diseases threatening the health and productivity of livestock in Africa and Latin America. Trypanosoma vivax is mainly transmitted by tsetse fies; however, the parasite has also acquired the ability to be transmitted mechanically by hematophagous dipterans. Understanding its distribution, host range and prevalence is a key step in local and global efforts to control the disease.

Methods

The study was conducted according to the methodological recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. A systematic literature search was conducted on three search engines, namely PubMed, …

Molecular Identification Of Parasites In An Intestinal Coprolite From A Mummified Religious Dignitary Of The Piraino Mother Church Crypt, Sicily, Amanda Rollins, Krystiana Krupa, Georgia Millward, Dario Piombino-Mascali, Karl Reinhard, Frederika Kaestle

Karl Reinhard Publications

Intestinal contents were sampled from a spontaneously enhanced mummy from the Sepulcher of the Priests of the Piraino Mother Church in the Province of Messina, Sicily. This adult male mummy, Piraino 1, is an unidentified religious dignitary dating from the late-18th to mid-19th centuries. Immunological and molecular diagnostics were used to test for common and clinically significant parasites. A morphological diagnosis of Trichuris trichiura (whipworm) was confirmed genetically. A previously undetected Enterobius vermicularis (pinworm) infection was also identified genetically. These data indicate that the Piraino 1 individual was simultaneously infected with multiple intestinal parasite species indicative of poor hygiene. This …

Text Mining To Identify The Origin Of Chronic Wasting Disease, G. Webb

Faculty Research, Scholarly, and Creative Activity

Chronic wasting disease (CWD) is a 100 percent fatal, prion disease of deer that has the potential to decimate the deer population and jump to the human population. A simple Google search on the “origin of chronic wasting disease” yielded a total of 56 relevant articles. Of these, 75 percent report that the origin is unknown, 19.6 percent report that the disease may have originated in a Fort Collins, Colorado, government research facility, and 5.4 percent report other possible origins. Government sources reported the Fort Collins theory 4.3 percent of the time while non-governmental sources, such as news articles, reported …