Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Biology (7)
- Cell and Developmental Biology (6)
- Microbiology (6)
- Genetics (5)
- Biotechnology (3)
-
- Cell Biology (3)
- Diseases (2)
- Ecology and Evolutionary Biology (2)
- Medicine and Health Sciences (2)
- Neoplasms (2)
- Amino Acids, Peptides, and Proteins (1)
- Bacteriology (1)
- Biochemistry (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Cell Anatomy (1)
- Chemicals and Drugs (1)
- Developmental Biology (1)
- Immunology and Infectious Disease (1)
- Immunopathology (1)
- Laboratory and Basic Science Research (1)
- Medical Biochemistry (1)
- Medical Sciences (1)
- Molecular Biology (1)
- Pathogenic Microbiology (1)
- Systems Biology (1)
- Institution
- Keyword
-
- Africa (1)
- Alignment (1)
- Animals (1)
- Anura (1)
- Blood Proteins (1)
-
- Brevicipitinae (1)
- Complement C4 (1)
- Cystic Fibrosis (1)
- DNA-Binding Proteins (1)
- Drosophila (1)
- Drosophila Proteins (1)
- Eastern Arc (1)
- Escherichia coli (1)
- Eve (1)
- Gene Expression Regulation, Developmental (1)
- Gene sequencing (1)
- Genetic network (1)
- Genetics (1)
- Hemisus (1)
- Homeodomain (1)
- Homeodomain Proteins (1)
- Klebsiella pneumoniae (1)
- Lissamphibia (1)
- Melanobatrachinae (1)
- Microhylidae (1)
- Mitochondrial genes (1)
- Mutation detection (1)
- Nuclear Proteins (1)
- PCR (1)
- Pair-rule gene (1)
- Publication
- Publication Type
Articles 1 - 11 of 11
Full-Text Articles in Molecular Genetics
Phylogenetic Relationships Of African Microhylid Frogs Inferred From Dna Sequences Of Mitochondrial 12s And 16s Rrna Genes, Simon P. Loader, David J. Gower, Kim M. Howell, Nike Doggart, Mark-Oliver Rödel, Barry T. Clarke, Rafael O. De Sá, Bernard L. Cohen, Mark Wilkinson
Phylogenetic Relationships Of African Microhylid Frogs Inferred From Dna Sequences Of Mitochondrial 12s And 16s Rrna Genes, Simon P. Loader, David J. Gower, Kim M. Howell, Nike Doggart, Mark-Oliver Rödel, Barry T. Clarke, Rafael O. De Sá, Bernard L. Cohen, Mark Wilkinson
Biology Faculty Publications
The phylogenetic relationships of microhylid frogs are poorly understood. The first molecular phylogeny for continental African microhylids is presented, including representatives of all subfamilies, six of the eight genera, and the enigmatic hemisotid Hemisus. Mitochondrial 12S and 16S rRNA sequence data were analysed using parsimony, likelihood and Bayesian methods. Analyses of the data are consistent with the monophyly of all sampled subfamilies and genera. Hemisus does not nest within either brevicipitines or non-brevicipitines. It is possibly the sister group to brevicipitines, in which case brevicipitines might not be microhylids. Phrynomantis and Hoplophryne potentially group with non-African, non-brevicipitine microhylids, in …
The Potential Role Of Ledgf/P75 In Prostate Cancer, Tracy Ruth Daniels
The Potential Role Of Ledgf/P75 In Prostate Cancer, Tracy Ruth Daniels
Loma Linda University Electronic Theses, Dissertations & Projects
The serum autoantibody repertoire from cancer patients is currently being exploited for the identification of tumor associated antigens (TAA) and the design of TAA arrays. Such arrays would facilitate autoantibody profiling and potentially aid in the serological diagnosis and prognosis of tumors. The goal of this study was to identify and characterize prostate-specific TAA. We observed that while the general frequency and titers of autoantibodies in PCa patients were relatively similar to those in matched controls, significant differences could be detected between the two groups in the autoantibody response to the lens epithelial-derived growth factor p75 (LEDGF/p75). LEDGF/p75 is a …
The Bvg Virulence Control System Regulates Biofilm Formation In Bordetella Bronchiseptica, Yasuhiko Irie, Seema Mattoo, Ming H. Yuk
The Bvg Virulence Control System Regulates Biofilm Formation In Bordetella Bronchiseptica, Yasuhiko Irie, Seema Mattoo, Ming H. Yuk
Biology Faculty Publications
Bordetella species utilize the BvgAS (Bordetella virulence gene) two-component signal transduction system to sense the environment and regulate gene expression among at least three phases: a virulent Bvg+ phase, a nonvirulent Bvg− phase, and an intermediate Bvgi phase. Genes expressed in the Bvg+ phase encode known virulence factors, including adhesins such as filamentous hemagglutinin (FHA) and fimbriae, as well as toxins such as the bifunctional adenylate cyclase/hemolysin (ACY). Previous studies showed that in the Bvgi phase, FHA and fimbriae continue to be expressed, but ACY expression is significantly downregulated. In this report, we determine …
Ionizing Radiation And Endostatin Gene Therapy Against Lung Tumor, Xian Luo
Ionizing Radiation And Endostatin Gene Therapy Against Lung Tumor, Xian Luo
Loma Linda University Electronic Theses, Dissertations & Projects
Although many advances have been made in radiotherapy, tumor radioresistance and normal tissue damage continue to always be important issues for radiation oncologists. Numerous reports have also documented that radiation exposure increases the risk for malignancy and suppresses immune mechanisms. However, increasing evidence has suggested that anti-angiogenic therapy that targets tumor blood supply may alter abnormal tumor vasculature, thus synergizing radiotherapy. The governing hypothesis of the present study was that modification of tumor vasculature by antiangiogenic gene therapy can increase the efficacy of radiotherapy and that radiation can also improve DNA transfection efficiency by increasing expression of the administered gene. …
Drawing Lines In The Sand: Even Skipped Et Al. And Parasegment Boundaries., James B. Jaynes, Miki Fujioka
Drawing Lines In The Sand: Even Skipped Et Al. And Parasegment Boundaries., James B. Jaynes, Miki Fujioka
Department of Biochemistry and Molecular Biology Faculty Papers
The pair-rule segmentation gene even skipped (eve) is required to activate engrailed stripes and to organize odd-numbered parasegments (PSs). The protein product Eve has been shown to be an active repressor of transcription, and recent models for Eve function suggest that activation of engrailed is indirect, but these models have not been fully tested. Here we identify the forkhead domain transcription factor Sloppy-paired as the key intermediate in the initial activation of engrailed by Eve in odd-numbered parasegments. We also analyze the roles of the transcription factors Runt and Odd-skipped in this process. Detailed analysis of engrailed and pair-rule gene …
Pcr And 16s Rdna Sequencing For Identifying And Comparing Gram-Negative Bacteria, Molly Truax
Pcr And 16s Rdna Sequencing For Identifying And Comparing Gram-Negative Bacteria, Molly Truax
Honors Capstones
Capstone submitted as a graduation requirement for the BSU Honors Program.
Drosophila As An Emerging Model To Study Metastasis, Madhuri Kango-Singh, Georg Halder
Drosophila As An Emerging Model To Study Metastasis, Madhuri Kango-Singh, Georg Halder
Biology Faculty Publications
Metastasis is the primary cause of human cancer-related deaths. Two recent studies describe a system for testing how multiple genetic events synergize to promote neoplastic growth and metastasis in Drosophila, paving the way for systematic approaches to understanding metastasis using the powerful tools of Drosophila genetics.
The Biological Burden Of Antibiotic Resistance In Staphylococcus Aureus, Natasha Samantha Dean
The Biological Burden Of Antibiotic Resistance In Staphylococcus Aureus, Natasha Samantha Dean
Loma Linda University Electronic Theses, Dissertations & Projects
Antibiotic resistance is a major problem. Resistance is often mediated by genes on bacterial plasmids and dissemination of resistance is commonly achieved by plasmid transfer. The mechanisms of resistance that are presently understood suggest that resistance is energetically costly. If this is generally true, resistance would reduce the fitness of cells in the absence of antibiotics. We examined the hypothesis that resistance reduces the fitness of microorganism and requires continuous selection to be maintained. To test this hypothesis, we measured the effects of plasmid-borne resistance genes on cell growth by comparing the growth rates of Staphylococcus aureus with and without …
Phylogenetic Signal And The Utility Of 12s And 16s Mtdna In Frog Phylogeny, S. Hertwig, Rafael O. De Sá, A. Haas
Phylogenetic Signal And The Utility Of 12s And 16s Mtdna In Frog Phylogeny, S. Hertwig, Rafael O. De Sá, A. Haas
Biology Faculty Publications
Genes selected for a phylogenetic study need to contain conserved information that reflects the phylogenetic history at the specific taxonomic level of interest. Mitochondrial ribosomal genes have been used for a wide range of phylogenetic questions in general and in anuran systematics in particular. We checked the plausibility of phylogenetic reconstructions in anurans that were built from commonly used 12S and 16S rRNA gene sequences. For up to 27 species arranged in taxon sets of graded inclusiveness, we inferred phylogenetic hypotheses based on different apriori decisions, i.e. choice of alignment method and alignment parameters, including/excluding variable sites, choice of reconstruction …
Morphological Characteristics And Species Separation Of Hawaiian Postlarval Amphidromous Fishes, M. Eric Benbow, Albert J. Burky, Carl M. Way
Morphological Characteristics And Species Separation Of Hawaiian Postlarval Amphidromous Fishes, M. Eric Benbow, Albert J. Burky, Carl M. Way
Biology Faculty Publications
There are five Hawaiian amphidromous fishes (Gobiidae: Lentipes concolor, Awaous guamensis, Sicyopterus stimpsoni, Stenogobius hawaiiensis; Eleotridae: Eleotris sandwicensis). Amphidromous adults deposit eggs on the stream bottom. After hatching, larvae drift to the ocean for growth followed by postlarval migration back into the streams. Postlarvae were collected to construct a dichotomous identification key based on 12 morphological measures and ray counts from four fins. Overall, the presense of fused pelvic fins, standard length (SL), and fin ray numbers were the most useful in species separation. Gobies were separated from the eleotrid by the former having fused …
Detection Of Five Common Cftr Mutations By Rapid-Cycle Real Time Amplification Refractory Mutation System Pcr., Eugene Dempsey, David Barton, Fergus Ryan
Detection Of Five Common Cftr Mutations By Rapid-Cycle Real Time Amplification Refractory Mutation System Pcr., Eugene Dempsey, David Barton, Fergus Ryan
Articles
No abstract provided.