Genetics and Genomics Commons^™

Review Of "The Nature And Origin Of The Biological World" By E. J. Ambrose, John B. Jenkins

Biology Faculty Works

No abstract provided.

Audiological Characteristics Of The Monge Family Of Costa Rica, Christine Moulton

Dissertations and Theses

The audiological characteristics of the Monge family of Costa Rica were investigated in a sample of fifty-two affected members and twelve unaffected members. Through laboratory analysis by staff personnel from the University of Costa Rica and audiological test results obtained in the present investigation, it was concluded that affected Monge members demonstrate a slowly progressive low frequency sensorineural hearing loss of autosomal dominant transmission. The initial site of lesion appears to be the apical portion of the cochlea, with significant onset occurring during early childhood following normal speech and language acquisition. The rate at which the hearing loss progresses and …

Natural Killer Activity In Gardner's Syndrome, Ann Marie Stembridge

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Gardner's syndrome is an autosomal dominant disease presenting multiple colonic polyps with a predisposition for malignant change. In addition to colonic polyp formation by early adolescence, extracolonic lesions appear often prior to polyp formation. One theoretical mechanism for the origin of polyps and malignancies in Gardner's syndrome is a genetic defect in the natural killer cell activity of patients with this disease. Natural killer cells are a subpopulation of lymphocytes that spontaneously lyse tumor cells and virally transformed cells. A study was undertaken to determine the natural killer activity of patients with Gardner's syndrome.

A technique termed chromium release was …

On The Distribution And Characteristics Of Isozyme Expression In Mycoplasma, Acholeplasma, And Ureaplasma Species, Stephen J. O'Brien, Janice M. Simonson, S. Razin, Michael F. Barile

Biology Faculty Articles

A summary of a survey of three genera of mycoplasmatales (Mycoplasma, Acholeplasma, and Ureaplasma) for isozyme expression is presented. Isozyme analysis of mycoplasmas has been employed in at least three distinct areas: (1) as genetic markers for identification, individualization, and taxonomic classification; (2) as markers for cell culture contamination; and (3) as a qualitative measure of the operative metabolic pathways in the diverse species. We have found five ubiquitous enzymes: purine nucleoside phosphorylase, adenylate kinase, inorganic pyrophosphatase, dipeptidase, and esterase. Three enzymes, glucose-6-phosphate dehydrogenase, phosphogluconate dehydrogenase, and superoxide dismutase, were restricted to Acholeplasma species and were not …

Genetic Divergence Within The Genus Liriodendron (Magnoliaceae), Jonathan F. Wendel, Clifford R. Parks, Norton G. Miller, Karen M. Mcdougal

Jonathan F. Wendel

The genus Liriodendron L. consists of a southeast Asian-eastern North American disjunct species pair, but the genus had a much wider distribution in the Northern Hemisphere during the late Cretaceous and the Tertiary. Although generally similar in morphology, the two extant species are measurably different. In 1973 and 1977 they were hybridized, and interspecific heterosis was observed in the progeny. After seven years, the interspecific hybrids synthesized in 1973 had a significantly greater biomass than intraspecific hybrids of L. tulipifera. The growth rate of interspecific and intraspecific F2 seedlings was approximately equal. A preliminary survey of flavonoid extracts in L. …

Occlusion Of Vision In Old English Sheepdogs, Michael W. Fox

Veterinary Science and Medicine Collection

The show standards established for many breeds of dogs have been linked with a number of genetically related abnormalities that can result in unnecessary suffering. The facial skin folds and shortened face of bulldogs, which respectively lead to chronic dermatitis and respiratory difficulties, are two dramatic examples. Likewise, ear-cropping is an ethically questionable mutilation that conveys no benefit upon the dog. Another serious welfare concern relates to a practice that is common among owners of Old English sheepdogs and other breeds with long facial hair: allowing the hair to cover the animal's eyes. This feature is considered a desirable show …

Genetic Adaptation And Welfare, J. Van Rooijen

Genetics Collection

Beilharz says: "The evolutionary processes, if they are not obstructed or misdirected, must lead to such a degree of adaptation that welfare will have to be taken for granted, just as we can do no better than to take for granted the welfare of any wild animal in its natural habitat." From this statement, one might conclude all we have to do is wait, and the animals will eventually adapt to intensive systems. Concerning animals put into new kinds of environments, he states that, if individuals do not have the capacity to adjust phenotypically, "adaptation of the population will require …

Aspen Management Guidelines For The Grand Mesa, Uncompahgre And Gunnison National Forest, Aspen Management Task Force

Aspen Bibliography

A task force was formed in late April 1983 for the purpose of developing guidelines for Aspen Management on the Grand Mesa, Uncompahgre and Gunnison National Forests.

Origin Of Human Trisomy 21 Mosaicism, Diane Dusenbery Waggoner

Dissertations and Theses

Down Syndrome is a human condition caused by an extra copy of a #21 chromosome. At least one to two percent of free (not translocated) trisomy 21 cases are mosaics, i.e., they have two or more distinct cell lines. Usually, one cell line is 47 ,XX or XY ,+21 while the other cell line is normal 46,XX or 46,XY.

The purpose of the study was to establish the etiologies of the separate cell lines by determining whether the zygote was trisomic or normal. Meiotic non-disjunction in the formation of a gamete could lead to a trisomic zygote; loss of a …