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Full-Text Articles in Genetics and Genomics

Dispermic Origin And Clinical Outcome Of Three Complete Hydatidiform Moles With 46,Xy Karyotype, U. Surti, A. E. Szulman, S. O'Brien Sep 1982

Dispermic Origin And Clinical Outcome Of Three Complete Hydatidiform Moles With 46,Xy Karyotype, U. Surti, A. E. Szulman, S. O'Brien

Biology Faculty Articles

Three new cases of complete, classic hydatidiform mole with a 46,XY karyotype are described. They originated by dispermy as demonstrated by chromosome and enzyme analyses. Levels of human chorionic gonadotropin decreased to normal spontaneously within a short time, indicating a benign course in these three cases. Of a total of 18 cases reported to date, postoperative clinical information was available for 10 patients. Two of these 10 patients had a malignant course with lung metastases. It is of theoretical and clinical importance to establish the magnitude of the risk of malignancy for hydatidiform mole with a 46,XY karyotype. © 1982.


Cole1 Copy Number Mutants., Londa Schmidt, Joseph Inselburg Aug 1982

Cole1 Copy Number Mutants., Londa Schmidt, Joseph Inselburg

Dartmouth Scholarship

A deletion mutant of the colicin E1-derived plasmid, pDMS6642, exhibited an approximately fourfold increase in copy number. We subsequently isolated hydroxylamine-induced mutants of that plasmid that had a further increase in copy number. Analysis of them suggests that the increased copy number of pDMS6642 is associated with transcriptional readthrough from a Tn3 transposon into the region of ColE1 containing information that influences plasmid replication. The hydroxylamine mutation in one copy number mutant appeared to increase the plasmid copy number by stimulating readthrough transcription from the Tn3 transposon into the ColE1 replication control region, whereas the other hydroxylamine mutation acts by …


Evidence For The Horizontal Acquisition Of Murine Akr Virogenes By Recent Horizontal Infection Of The Germ Line, Stephen J. O'Brien, Janet L. Moore, Malcolm A. Martin, James E. Womack Apr 1982

Evidence For The Horizontal Acquisition Of Murine Akr Virogenes By Recent Horizontal Infection Of The Germ Line, Stephen J. O'Brien, Janet L. Moore, Malcolm A. Martin, James E. Womack

Biology Faculty Articles

Several recent reports have established the biological and molecular genetic similarity between the endogenous AKV virus of strain AKR, and an N-ecotropic endogenous virus found in the genome of feral Japanese mice, Mus musculus molossinus. The similarities are so striking as to suggest a common origin of these viruses, which are present in some, but not all, inbred mouse strains. The virogenes of AKR mice may have been acquired by either: (a) common descent of AKR (and other AKV+ strains) from a common ancestor of AKR and molossinus animals, or (b) horizontal germ line infection of the AKR …


A Remarkable New Species Of Salamander Allied To Bolitoglossa Altamazonica (Plethodontidae) From Southern Peru, David B. Wake, Arden H. Brame, Jr., Richard Thomas Mar 1982

A Remarkable New Species Of Salamander Allied To Bolitoglossa Altamazonica (Plethodontidae) From Southern Peru, David B. Wake, Arden H. Brame, Jr., Richard Thomas

Occasional Papers of the Museum of Natural Science, Louisiana State University

No abstract provided.


Synthesis Of Low Molecular Weight Heat Shock Peptides Stimulated By Ecdysterone In A Cultured Drosophila Cell Line., Robert C. Ireland, Edward M. Berger Feb 1982

Synthesis Of Low Molecular Weight Heat Shock Peptides Stimulated By Ecdysterone In A Cultured Drosophila Cell Line., Robert C. Ireland, Edward M. Berger

Dartmouth Scholarship

Treatment of Schneider's line 3 Drosophila cells with the steroid hormone ecdysterone rapidly stimulated the synthesis and accumulation of the polypeptide previously designated p7 [Berger, E. M., Ireland, R. C. & Wyss, C. (1980) Somatic Cell Genet. 6, 119-129]. In this report, p7 is identified as the 23,000-dalton heat shock polypeptide (hsp23). In addition to hsp23, the synthesis of the low molecular weight heat shock polypeptides hsp22, hsp26, and hsp27 was also stimulated by ecdysterone, although to different extents. Hybridization of a nick-translated genomic clone containing the hsp23 gene to a total RNA blot showed that ecdysterone stimulation of hsp23 …


Genetic Adaptation In Relation To Animal Welfare, R. G. Beilharz Jan 1982

Genetic Adaptation In Relation To Animal Welfare, R. G. Beilharz

Genetics Collection

In this essay I outline the processes of adaptation of animals and of animal populations and discuss their relevance to the problem of animal welfare. Because "animal welfare" has many different aspects including philosophical, ethical, and biological, it is important to examine some of the fundamental issues that underly the concept. Hence, in this essay, I comment on how people come to "know," how information accumulates, and how what we know influences our actions. I also discuss the biological information that is relevant to animal welfare. It is my hope that, when this topic has been placed within a broader …


Speciation In The Aedes Triseriatus Species Complex, David B. Taylor Jan 1982

Speciation In The Aedes Triseriatus Species Complex, David B. Taylor

David B Taylor

Interspecific hybridization was used to determine the genetic relationships between the four species of mosquitoes in the Triseriatus and Zoosophus groups of the aedine subgenus Protomacleaya (Diptera: Culicidae). Four factors were investigated: 1) fertility of intra- and interspecific crosses, 2) morphology of the interspecific hybrids and the genetic bases of morphological characters, 3) modes of postcopulatory reproductive isolation and 4) types of chromosomal changes occurring during and subsequent to the divergence of the species. Hybrid progeny were produced in 11 of the 12 possible crosses between the four species. Only the Aedes zoosophus female X A. brelandi male cross failed …


An Experiment In Biomass Production: Results From Three Consecutive Harvests Of Cottonwood Alder, Constance A. Harrington, Dean S. Debell, Robert F. Strand Jan 1982

An Experiment In Biomass Production: Results From Three Consecutive Harvests Of Cottonwood Alder, Constance A. Harrington, Dean S. Debell, Robert F. Strand

Aspen Bibliography

No abstract provided.


Understory-Overstory Vegetation Relationships: An Annotated Bibliography, Peter F. Ffolliott, Warren P. Clary Jan 1982

Understory-Overstory Vegetation Relationships: An Annotated Bibliography, Peter F. Ffolliott, Warren P. Clary

Aspen Bibliography

No abstract provided.


The Extent And Characteristics Of Low Productivity Aspen Areas In Minnesota, Garhard K. Raile, Jerold T. Hahn Jan 1982

The Extent And Characteristics Of Low Productivity Aspen Areas In Minnesota, Garhard K. Raile, Jerold T. Hahn

Aspen Bibliography

No abstract provided.


Biomass Equations For Ten Major Tree Species Of The Prairie, T. Singh Jan 1982

Biomass Equations For Ten Major Tree Species Of The Prairie, T. Singh

Aspen Bibliography

No abstract provided.


Wildlife Conservation In The Soviet Union, Michael L. Wolfe, Douglas R. Weiner Jan 1982

Wildlife Conservation In The Soviet Union, Michael L. Wolfe, Douglas R. Weiner

Aspen Bibliography

No abstract provided.


Wildlife--Wild Death: Kenya's Man-Animal Equation, Norman N. Miller Jan 1982

Wildlife--Wild Death: Kenya's Man-Animal Equation, Norman N. Miller

Aspen Bibliography

Kenya's game laws, in comparison to those of ancient England, are tame and mild.


Speciation In The Aedes Triseriatus Species Complex., David B. Taylor Dec 1981

Speciation In The Aedes Triseriatus Species Complex., David B. Taylor

David B. Taylor

Interspecific hybridization was used to determine the genetic relationships between the four species of mosquitoes in the Triseriatus and Zoosophus groups of the aedine subgenus Protomacleaya (Diptera : Culicidae) . Four factors were investigated : 1) fertility of intra- and interspecific crosses, 2) morphology of the interspecific hybrids and the genetic bases of morphological characters, 3) modes of postcopulatory reproductive isolation and 4) types of chromosomal changes occurring during and subsequent to the divergence of the species .

Hybrid progeny were produced in 11 of the 12 possible crosses between the four species . Only the Aedes zoosophus female X …