Genetics and Genomics Commons^™

Origin Of Human Trisomy 21 Mosaicism, Diane Dusenbery Waggoner

Dissertations and Theses

Down Syndrome is a human condition caused by an extra copy of a #21 chromosome. At least one to two percent of free (not translocated) trisomy 21 cases are mosaics, i.e., they have two or more distinct cell lines. Usually, one cell line is 47 ,XX or XY ,+21 while the other cell line is normal 46,XX or 46,XY.

The purpose of the study was to establish the etiologies of the separate cell lines by determining whether the zygote was trisomic or normal. Meiotic non-disjunction in the formation of a gamete could lead to a trisomic zygote; loss of a …

Cytologic Characterization Of Human Constitutive Heterochromatin, Timothy Atchison Donlon

Dissertations and Theses

A study was conducted to cytologically map certain subsets of constitutive heterochromatin onto specific portions of human chromosomes. This involved sequentially staining metaphase chromosomes from lymphocytes first with the Centromeric Dot, Giemsa-11, G-banding or Lateral Asymmetry staining techniques, which are cytochemical methods which stain particular chromosomes or chromosomal regions. Then those same metaphase chromosomes were stained using the C-banding technique, a method which is believed to denote constitutive heterochromatin. With the exception of the G-banding technique, areas depicted by the special staining techniques were found to reside only within the areas stained by the C-band technique and are thus believed …

An Analysis Of Staggered Spondaic Word Test Performances Of Dyslexic Children And Their Parents, Nancy Jane Maxwell

Dissertations and Theses

The purpose of this study was to investigate the possibility of a familial lineage for dyslexia by analyzing certain auditory processing characteristics of dyslexic children and their parents. The Staggered Spondaic Word test was administered to twenty-one dyslexic children, eight to thirteen years of age, their natural parents and normal reading siblings.

The experimental test data were tabulated and analyzed according to listening condition for each of the four groups: dyslexic children, normal reading siblings, affected parents and non-affected parents. A statistical analysis of the experimental data revealed significantly poorer Staggered Spondaic Word test performances for dyslexic children and their …

"Biological Determinism As A Social Weapon", Richard C. Lewontin

Special Collections: Oregon Public Speakers

No abstract provided.

A Test Of The Simple Recessive Hypothesis For The Inability To Taste Phenyl-Thio-Urea: A Family Study, Susan I. Wolf

Dissertations and Theses

This thesis is a report on the analysis of family data gathered to test the simple recessive hypothesis for the inability to taste phenyl-thio-urea (P.T.C.). The simple recessive hypothesis states that the inability of a minority of persons to taste high concentrations of P.T.C. is due to the action of an autosomal recessive gene in the homozygous condition.