Open Access. Powered by Scholars. Published by Universities.®

Genetics and Genomics Commons™

Open Access. Powered by Scholars. Published by Universities.®

PDF

University of Arkansas, Fayetteville

Discipline
Keyword
Publication Year
Publication
Publication Type

Articles 91 - 105 of 105

Full-Text Articles in Genetics and Genomics

Applications Of Variable Number Tandem Repeat Genotyping In The Validation Of An Animal Medical Model And Gene Flow Studies In Threatened Populations Of Reptiles, Candace D. Smith Dec 2009

Applications Of Variable Number Tandem Repeat Genotyping In The Validation Of An Animal Medical Model And Gene Flow Studies In Threatened Populations Of Reptiles, Candace D. Smith

Graduate Theses and Dissertations

We used variable number tandem repeats (VNTR) to validate the chicken as a human medical model for Pulmonary Arterial Hypertension. We identified seven regions on four chromosomes and interrogated for VNTR markers that significantly associate with Pulmonary Hypertension Syndrome/ascites. In those regions, we identified 7 candidate genes; AGTR1, ACE, p38MAPK, SST, 5HT2B, NET1, and CALM3 for further analysis as significantly contributing QTL for ascites/PHS. We also used variable number tandem repeats to measure gene flow and gather evidence for multiple paternity in a population of Timber rattlesnakes, Crotalus horridus. We were able to verify 1 VNTR that can be used …

Go to article

Letter From The Dean, Lalit Verma Jan 2009

Letter From The Dean, Lalit Verma

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Go to article

Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles—E,E+, And Erh, Rupali Ugrankar, Kim Cheng, Ronald Okimoto Jan 2003

Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles—E,E+, And Erh, Rupali Ugrankar, Kim Cheng, Ronald Okimoto

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

The melanocortin 1-receptor (MC1-R) gene plays a key role in the expression of fur and feather color in mammals and birds by regulating the distribution of two melanin pigments: eumelanin (black/brown) and pheomelanin (red/yellow). MC1-R corresponds to the classical Extension (E) locus in mice, pigs, dogs, horses, and chickens. Three E locus alleles, the wild-type (e+), brown (E), and redhead (erh) have been identified in Japanese quail (Coturnix japonica). To determine if the quail E locus phenotypes were due to variation in the MC1-R gene, the coding region of the MC1-R gene was PCR amplified and DNA sequenced using genomic …

Go to article

Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles, E, E+, Erh, Rupali B. Ugrankar Jan 2003

Dna Sequence Of Melanocortin 1-Receptor Gene In Coturnix Japonica: Correlation With Three E Locus Alleles, E, E+, Erh, Rupali B. Ugrankar

Inquiry: The University of Arkansas Undergraduate Research Journal

The melanocortin 1-receptor (MC1-R) gene plays a key role in the expression of fur and feather color in mammals and birds by regulating the distribution of two melanin pigments: eumelanin (black/brown) and pheomelanin (red/yellow). MC1-R corresponds to the classical Extension (E) locus in mice, pigs, dogs, horses, and chickens. Three E locus alleles, the wild-type (e + ), brown (E), and redhead (e rh) have been identified in Japanese quail (Coturnix japonica). To determine if the quail E locus phenotypes were due to variation in the MC1-R gene, the coding region of the MC1-R gene was PCR amplified and DNA …

Go to article

Photoreactivation Of Lethal Damage Induced In Hamster X Xenopus Hybrid Cells And Their Parentals By Uv Light, David Bohlender, Stuart Williams, Emir Cruz, H. Gaston Griggs Jan 1987

Photoreactivation Of Lethal Damage Induced In Hamster X Xenopus Hybrid Cells And Their Parentals By Uv Light, David Bohlender, Stuart Williams, Emir Cruz, H. Gaston Griggs

Journal of the Arkansas Academy of Science

A85 Xenopus cells that exhibited a high level of photoreactivation (PR) and V79B2 hamster cells that exhibited little PR were fused to produce the V79B2 x A85 cell line — a hybrid line which possessed a relatively stable karyotype, with most cells containing the entire V79B2 and A85 genomes. UV and UV plus PR fluence-survival relations were then determined and compared for the hybrid and parental lines in a first attempt to elucidate interactions of the parental PR mechanisms in the hybrid. It was anticipated that the A85 genome in the hybrid would produce PR enzyme in sufficient concentration and …

Go to article

Ultraviolet Light Reactivation Of Gamma-Ray Induces Chromosome Aberrations In G1 Phase Xenopus Cells, Susan Kulp, Linda Rogers, H. Gaston Griggs Jan 1984

Ultraviolet Light Reactivation Of Gamma-Ray Induces Chromosome Aberrations In G1 Phase Xenopus Cells, Susan Kulp, Linda Rogers, H. Gaston Griggs

Journal of the Arkansas Academy of Science

No abstract provided.

Go to article

Heterochromatic Patterns In Drosophila Virilis Interphase Nuclei, William C. Guest Jan 1980

Heterochromatic Patterns In Drosophila Virilis Interphase Nuclei, William C. Guest

Journal of the Arkansas Academy of Science

No abstract provided.

Go to article

Some Effects Of Methyl Green On Expression Of Damage Induced In G1 Xenopus Cells By Ultraviolet Light, Keith E. Mathias, H. Gaston Griggs Jan 1980

Some Effects Of Methyl Green On Expression Of Damage Induced In G1 Xenopus Cells By Ultraviolet Light, Keith E. Mathias, H. Gaston Griggs

Journal of the Arkansas Academy of Science

No abstract provided.

Go to article

Electrophoretic Analysis Of Blood Serum Proteins In Three Species Of Water Snakes (Genus Nerodia), Phyllis J. Garnett Jan 1979

Electrophoretic Analysis Of Blood Serum Proteins In Three Species Of Water Snakes (Genus Nerodia), Phyllis J. Garnett

Journal of the Arkansas Academy of Science

Serum from three species of water snakes (Nerodia rhombifera, N. erythrogaster and N. fasciata) from one geographic region was analyzed electrophoretically on cellulose acetate, and anodic mobility and relative concentration of the fractions were determined by a recording densitometer with an automatic integrator. Classification of fractions was based on mobility (Rf, values), and for identification purposes, bands were labeled in order of decreasing mobility (albumin and alpha₁, alpha₂, alpha₃, beta₁, beta₂, gamma₁, and gamma₂ globulins). Seven fractions were identified in each species with alpha₃ being absent from N. rhombifera and N. erythrogaster, and only one gamma fraction was observed in …

Go to article

Genic Variation In White-Tailed Deer From Arkansas, Phyllis K. Price, Michael E. Cartwright, Mitchell J. Rogers Jan 1979

Genic Variation In White-Tailed Deer From Arkansas, Phyllis K. Price, Michael E. Cartwright, Mitchell J. Rogers

Journal of the Arkansas Academy of Science

Liver and kidney samples of 33 white-tailed deer (Odocoileus virginianus) representing three populations in Arkansas were examined with horizontal starch gel electrophoresis. Of 17 loci examined, only PGM-1 and ES-2 exhibited polymorphism. Average individual heterozygosity, ranging from 2.3% to 4.7% with a mean of 3.1 %, was much lower than that reported for white-tailed deer in other parts of its range. The three populations examined in this study were highly similar based on Rogers' genetic similarity coefficient.

Go to article

Time Course Of Pr Of Uv-Induced Chromosomal Aberrations And Lethal Damage In G1 Xenopus Cells, Jan Payne, H. Gaston Griggs Jan 1977

Time Course Of Pr Of Uv-Induced Chromosomal Aberrations And Lethal Damage In G1 Xenopus Cells, Jan Payne, H. Gaston Griggs

Journal of the Arkansas Academy of Science

Synchronous cultures of early G1 cells were exposed to UV and their ability to photoreactivate lethal and aberrational damage was determined as a function of time following UV exposure. Lesions leading to cell death were converted to a non-photoreactivable state before cells entered S phase, while lesions leading to chromosomal aberrations were converted to a non-photoreactivable state as the cells entered S phase. These results indicate that the intracellular mechanism which expresses photoreactivable UV-induced lesions in G1 cells as cell death is not identical to the mechanism which expresses such lesions as chromosomal aberrations, and the two mechanisms operate primarily …

Go to article

Metaphase Configurations In Drosophila: A Comparison Of Endemic Hawaiian Species And Non-Endemic Species, Frances E. Clayton Jan 1976

Metaphase Configurations In Drosophila: A Comparison Of Endemic Hawaiian Species And Non-Endemic Species, Frances E. Clayton

Journal of the Arkansas Academy of Science

The metaphase configurations of 400 strains from 63 species of Hawaiian Drosophila were determined from squash preparations of larval brain tissue or spermatogenic cells from adult testes. These karyotypes include configurations from seven species not previously described. Metaphases of 148 Hawaiian species have been recorded, including species of the "picture-wing" group, the "modified mouthpart" group, and the "bristle-foot" group. A comparison between Hawaiian species and non-endemic species was made on the basis of chromosome numbers and configurations. Among the Hawaiian species, 85.8% have retained the primitive haploid configuration of five rods and one dot compared with only 34.8% of species …

Go to article

Electrophoretic Patterns Of Serum Proteins In Two Subspecies Of Odocoileus Virginianus, Greg S. Jackman, Phyllis J. Garnett Jan 1976

Electrophoretic Patterns Of Serum Proteins In Two Subspecies Of Odocoileus Virginianus, Greg S. Jackman, Phyllis J. Garnett

Journal of the Arkansas Academy of Science

Cellulose acetate electrophoresis revealed six monomorphic forms of serum protein in natural populations of two subspecies of white-tailed deer, Odocoileus virginianus virginianus from Tennessee and Odocoileus virginianus macroura from Arkansas. The fixed pattern of serum proteins in the two populations indicates a lack of genetic variation in the loci controlling these proteins. However, electrophoresis revealed different hemoglobin phenotypes in the two subspecies. This finding indicates that further study is needed to determine whether or not there are genetic differences in the hemoglobin forms

Go to article

Study Of Ultraviolet-Induces Chromatid And Chromosome Aberrations As A Function Of Dose In G1 Phase Vertebrate Tissue Cultures, Troy V. Orr, H. Gaston Griggs Jan 1976

Study Of Ultraviolet-Induces Chromatid And Chromosome Aberrations As A Function Of Dose In G1 Phase Vertebrate Tissue Cultures, Troy V. Orr, H. Gaston Griggs

Journal of the Arkansas Academy of Science

G1 phase A8 Xenopus laevis (toad) and V79B Cricetulus griseus (hamster) tissue cultures were used to observe the frequency of ultraviolet-induced chromosomal aberrations as a function of dose. When cultures are irradiated with ultraviolet light, visible aberrations are virtually absent until a threshold of approximately 80 ergs mm⁻¹ is reached. Aberrations then occur as a nonlinear function of dose. Chromatid aberrations are by far the most prevalent until doses in excess of 200 ergs mm⁻¹ are administered, at which point chromosome aberrations become common.

Go to article

Somatic Pairing In Drosophila Virilis Mitosis, William C. Guest Jan 1975

Somatic Pairing In Drosophila Virilis Mitosis, William C. Guest

Journal of the Arkansas Academy of Science

In neuroblast cells homologous chromosomes tend to pair during prophase of mitosis. Heterochromatic elements of homologous chromosomes are widely separated in very early prophase, at which time the euchromatin is poorly stained. Pairing is intimate for euchromatic portions of chromosomes in early and middle prophase with chiasmata frequently present. Homologous chromosomes most commonly lie side-by-side in late prophase and metaphase. Statistical data are presented to show the frequency of intimate pairing in prophase and side by side pairing in metaphase.

Go to article

First Prev