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Full-Text Articles in Food Chemistry
Biotransformation Of Polymethoxyflavones And Its Implication On Biological Activities, Minqi Wang
Biotransformation Of Polymethoxyflavones And Its Implication On Biological Activities, Minqi Wang
Doctoral Dissertations
In this thesis, the tissue distribution and in vivo biotransformation of nobiletin in rodents were demonstrated on three types of rodents, i.e.A-J female mice, CD-1 male mice and male F344 male rats. The effects of colonic metabolites of CD-1 mice on colonic carcinogenesis and inflammation were determined. In order to mimic the long-term dietary consumption of PMFs from food or dietary supplements, we applied oral administration by mixing PMFs with standard diet to rodents who have free access to food. Moreover, nobiletin (NBT), one of the most abundant PMFs in nature, and its major metabolties were incubated with mice …
Fabrication, Characterization And Biological Fate Of Phytochemical Delivery System, Jingjing Chen
Fabrication, Characterization And Biological Fate Of Phytochemical Delivery System, Jingjing Chen
Doctoral Dissertations
Polymethoxyflvones (PMFs) are a group compounds with promising cancer preventing activities and many other health benefits. There's a growing interest in fabricating delivery systems for PMFs as well as other phytochemicals due to their low water solubility. Firstly, we use nanoemulsion delivery system to encapsulate β-carotene. Sonication assisted method was developed to dissolve β-carotene to ensure minimum degradation. Powdered nanoemulsion was obtained after spray dry and freeze dry. Sample obtained after freeze dry showed better physiochemical characteristics. Then we use protein nanoparticle delivery system to encapsulate PMFS. The nanoparticle delivery system was fabricated by mixing the aqueous phase …