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Full-Text Articles in Population Biology
Development Of An In Silico Kir Genotyping Algorithm And Its Application To Population And Cancer Immunogenetic Analyses, Howard Rosoff
Development Of An In Silico Kir Genotyping Algorithm And Its Application To Population And Cancer Immunogenetic Analyses, Howard Rosoff
Dissertations & Theses (Open Access)
Gene content determination and variant calling in the complex KIR genomic region are useful for immune system function analysis, pathogenesis and disease risk factor elucidation, immunotherapy development, evolutionary investigations, and human migration modeling. Sequence-specific oligonucleotide and sequence-specific primer PCR methods are the de facto standards for KIR presence/absence identification, but the current platforms are unsuitable for SNP calling, impractical for KIR typing large cohorts of DNA samples, and inapplicable for typing repositories in which sequence data, but not cells or cell analytes, are available. Alternative typing methods, such as in silico sequence-based typing, can address the problems associated with amplicon-based …
Insights Into The Introduction Histories And Population Genetic Dynamics Of The Nile Monitor (Varanus Niloticus) And Argentine Black And White Tegu (Salvator Merianae) In Florida., Jared Price Wood
Electronic Theses and Dissertations
This dissertation examines the population genetic dynamics of two Florida invasives: the Nile monitor (Varanus niloticus) and Argentine black and white tegu (Salvator merianae). I also provide insights into the introduction histories of both species. This study was developed as part of a collaborative effort with the Florida Wildlife Commission to expand our knowledge of these highly detrimental, invasive lizards. All research activities involving animals and animal tissues were approved by the University of Louisville’s Institutional Animal Care and Use Committee (IACUC Proposal #: 12024). I start with a brief introduction into what makes invasive species …
Population Genetic Analysis Of Atlantic Horseshoe Crabs (Limulus Polyphemus) In Coastal Massachusetts., Katherine T. Johnson
Population Genetic Analysis Of Atlantic Horseshoe Crabs (Limulus Polyphemus) In Coastal Massachusetts., Katherine T. Johnson
Masters Theses
Atlantic horseshoe crabs (Limulus polyphemus) have endured decades of intense harvest pressure. Genetics studies have shown evidence of distinct sub-groups spanning the coast, although few fine-scale studies have been done to delineate these groups on a local level. Massachusetts lies directly between two of these sub-groups. With documented differences in prosomal widths of horseshoe crabs from either side of Cape Cod, it is possible that Cape Cod is a barrier to gene flow and that there are two distinct genetic groups within Massachusetts. Regulations currently consider all horseshoe crabs to be of one stock. I examined 6 microsatellite …
Genetic Differentiation Among Florida Populations Of Diadema Antillarum, Luke M. Chandler
Genetic Differentiation Among Florida Populations Of Diadema Antillarum, Luke M. Chandler
Honors Undergraduate Theses
This project used molecular genetic markers (microsatellites) to determine the amount of genetic diversity within populations and whether significant differentiation exists among Florida populations of the long-spined sea urchin, Diadema antillarum. Specifically, this project aimed to (1) compare genetic diversity of D. antillarum from six populations in south Florida ranging from Biscayne Bay, the Florida Keys, and Dry Tortugas, and (2) determine whether two broodstock populations of D. antillarum contain variation indicative of native Florida populations. Together, these questions can address whether broodstock populations contain the genetic variation necessary to meet the Florida Fish and Wildlife Conservation Commission’s (FWC’s) genetic …