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Articles 1 - 11 of 11
Full-Text Articles in Cancer Biology
Role Of Stat3/5 And Bcl-2/Xl In 2-Methoxyestradiol-Induced Endoreduplication Of Nasopharyngeal Carcinoma Cells, Cm Ting, Ck Wong, Rn Wong, Kw Lo, Aw Lee, Gs Tsao, Ml Lung, N.K. Mak
Role Of Stat3/5 And Bcl-2/Xl In 2-Methoxyestradiol-Induced Endoreduplication Of Nasopharyngeal Carcinoma Cells, Cm Ting, Ck Wong, Rn Wong, Kw Lo, Aw Lee, Gs Tsao, Ml Lung, N.K. Mak
Professor MAK, Nai Ki
2-methoxyestradiol (2ME2), an endogenous metabolite of 17-b-estradiol, has been shown to induce apoptosis and cell cycle arrest in various tumor models. We have previously shown that 2ME2 induced endoreduplication in a welldifferentiated nasopharyngeal carcinoma (NPC) HK-1 and a poorly differentiated C666-1 cell line. In the present study, we studied the survival factors involved in 2ME2-induced endoreduplicating NPC cells. In the HK-1 cells, knockdown of BcL-xL expression by siRNA resulted in the reduction of endoreduplication and an increase in the percentage of apoptosis. Further mechanistic study revealed that 2ME2 enhanced the expression of the phosphorylated form of STAT5 (p-STAT5-Y694), but not …
Targeted Inhibition Of The Egfr Pathways Enhances Zn-Bc-Am Pdt-Induced Apoptosis In Well-Differentiated Nasopharyngeal Carcinoma Cells, Hk Koon, Ps Chan, Rns Wong, Zg Wu, Ml Lung, Ck Chang, N.K. Mak
Targeted Inhibition Of The Egfr Pathways Enhances Zn-Bc-Am Pdt-Induced Apoptosis In Well-Differentiated Nasopharyngeal Carcinoma Cells, Hk Koon, Ps Chan, Rns Wong, Zg Wu, Ml Lung, Ck Chang, N.K. Mak
Professor MAK, Nai Ki
No abstract provided.
Gold Nanoparticle-Mediated Transfection Of Mammalian Cells, Sallie Smith Schneider, K.K. Sanhu, J.M. Simard, C.M. Mcintosh, V.M. Rotello
Gold Nanoparticle-Mediated Transfection Of Mammalian Cells, Sallie Smith Schneider, K.K. Sanhu, J.M. Simard, C.M. Mcintosh, V.M. Rotello
Sallie W Smith Schneider
No abstract provided.
Regulation Of The Immediate Early Gene Product C-Fos By Erk And Rsk: A Mechanism For Sensing And Propagating Erk Signal Duration, Sallie Smith Schneider, L.O. Murphy, R.H. Chen, D.C. Fingar, J. Blenis
Regulation Of The Immediate Early Gene Product C-Fos By Erk And Rsk: A Mechanism For Sensing And Propagating Erk Signal Duration, Sallie Smith Schneider, L.O. Murphy, R.H. Chen, D.C. Fingar, J. Blenis
Sallie W Smith Schneider
No abstract provided.
Mitogen Activated Protein Kinase Plays A Significant Role In Metaphase Ii Arrest, Spindle Morphology, And Maintenance Of Maturation Promoting Factor Activity In Bovine Oocytes, Sallie Smith Schneider, C.A. Gordo, C.L. He, R.A. Fissore
Mitogen Activated Protein Kinase Plays A Significant Role In Metaphase Ii Arrest, Spindle Morphology, And Maintenance Of Maturation Promoting Factor Activity In Bovine Oocytes, Sallie Smith Schneider, C.A. Gordo, C.L. He, R.A. Fissore
Sallie W Smith Schneider
No abstract provided.
Characterization Of A Mutant T Cell Hybridoma Line With Defects In Tcr-Mediated Apoptotic Pathway, Sallie Smith Schneider, G. Morgan, S.W. Smith, L. Pak, A. Marshak-Rothstein, R. Fissore, B.A. Osborne
Characterization Of A Mutant T Cell Hybridoma Line With Defects In Tcr-Mediated Apoptotic Pathway, Sallie Smith Schneider, G. Morgan, S.W. Smith, L. Pak, A. Marshak-Rothstein, R. Fissore, B.A. Osborne
Sallie W Smith Schneider
No abstract provided.
Private Pathways To A Common Death, Sallie Smith Schneider, B.A. Osborne
Private Pathways To A Common Death, Sallie Smith Schneider, B.A. Osborne
Sallie W Smith Schneider
No abstract provided.
Molecular Events In Thymocyte Apoptosis, Sallie Smith Schneider, B.A. Osborne
Molecular Events In Thymocyte Apoptosis, Sallie Smith Schneider, B.A. Osborne
Sallie W Smith Schneider
No abstract provided.
Apoptotic Signals Delivered Through The T-Cell Receptor Of A T-Cell Hybrid Require The Immediate-Early Gene Nur77, Sallie Smith Schneider, Z.G. Lui, K.A. Mclaughlin, L.M. Schwartz, B.A. Osborne
Apoptotic Signals Delivered Through The T-Cell Receptor Of A T-Cell Hybrid Require The Immediate-Early Gene Nur77, Sallie Smith Schneider, Z.G. Lui, K.A. Mclaughlin, L.M. Schwartz, B.A. Osborne
Sallie W Smith Schneider
No abstract provided.
Do All Programmed Cell Deaths Occur Via Apoptosis?, Sallie Smith Schneider, L.M. Schwartz, M.E.E Jones, B.A. Osborne
Do All Programmed Cell Deaths Occur Via Apoptosis?, Sallie Smith Schneider, L.M. Schwartz, M.E.E Jones, B.A. Osborne
Sallie W Smith Schneider
No abstract provided.
P53 Is Required For Radiation-Induced Apoptosis In Mouse Thymocytes, Sallie Smith Schneider, S.W. Lowe, E.M. Schmitt, B.A. Osborne
P53 Is Required For Radiation-Induced Apoptosis In Mouse Thymocytes, Sallie Smith Schneider, S.W. Lowe, E.M. Schmitt, B.A. Osborne
Sallie W Smith Schneider
No abstract provided.