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Cancer Biology Commons

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Full-Text Articles in Cancer Biology

Practice Notes: Strategies In Health Education Program, “Full Service”: Talking About Fighting Prostate Cancer—In The Barber Shop!, Lisa D. Lieberman, Mario C. Browne, Barbara Hager Aug 2007

Practice Notes: Strategies In Health Education Program, “Full Service”: Talking About Fighting Prostate Cancer—In The Barber Shop!, Lisa D. Lieberman, Mario C. Browne, Barbara Hager

Department of Public Health Scholarship and Creative Works

The purpose of this project is to promote prostate cancer screening, education about disease risk and the importance of early detection, and survivorship among African American males who frequent African American–owned barber shops.


Characterization Of Microrna Expression Levels And Their Biological Correlates In Human Cancer Cell Lines., Caifu Chen, Arti Gaur, David Jewell, Yu Liang, Dana Ridzon, Jason Moore, Victor Ambros, Mark Israel Mar 2007

Characterization Of Microrna Expression Levels And Their Biological Correlates In Human Cancer Cell Lines., Caifu Chen, Arti Gaur, David Jewell, Yu Liang, Dana Ridzon, Jason Moore, Victor Ambros, Mark Israel

Victor R. Ambros

MicroRNAs are small noncoding RNAs that function by regulating target gene expression posttranscriptionally. They play a critical role in developmental and physiologic processes and are implicated in the pathogenesis of several human diseases including cancer. We examined the expression profiles of 241 human microRNAs in normal tissues and the NCI-60 panel of human tumor-derived cell lines. To quantify microRNA expression, we employed a highly sensitive technique that uses stem-loop primers for reverse transcription followed by real-time PCR. Most microRNAs were expressed at lower levels in tumor-derived cell lines compared with the corresponding normal tissue. Agglomerative hierarchical clustering analysis of microRNA …