Cell and Developmental Biology Commons^™

Use Of Gene Profiling To Describe A Niche For Dendritic Cell Development, Geneviève Despars, Terence O'Neill, Helen O'Neill

Helen O'Neill

Gene profiling provides a multitude of data on individual gene expression. The view is expressed here that unreplicated data can be used in a descriptive way to compare cell populations in terms of their lineage characteristics and function. In these studies, the aim is to provide a snapshot of gene expression or its absence as a reflection of cell lineage or type, rather than gain a reliable expression measure for all genes expressed. The data set used in this analysis represents gene expression in the splenic stroma STX3 supportive of dendritic cell hematopoiesis and the lymph node stroma 2RL22, which …