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Full-Text Articles in Biology

To Feed Or Not To Feed: Examining The Effects Of Provisioning Tourism On Nurse Sharks In Caye Caulker, Belize, Carlee Jackson Aug 2020

To Feed Or Not To Feed: Examining The Effects Of Provisioning Tourism On Nurse Sharks In Caye Caulker, Belize, Carlee Jackson

All HCAS Student Capstones, Theses, and Dissertations

Wildlife tourism is increasing in popularity around the world, creating the need to understand alterations in animal behavior and spatial distributions that may occur due to associated anthropogenic disturbances. Nurse sharks (Ginglymostoma cirratum, Bonnaterre 1788) are commonly used for wildlife tourism within the Caye Caulker Marine Reserve in Belize. Shark and Ray Village (SRV) is a site within the reserve where nurse sharks are consistently fed by tour/snorkel boats to create an interactive experience with tourists, termed provisioning tourism. Prior to this experiment, no studies had been conducted in SRV to evaluate the impact of provisioning tourism (tourism …


The Evolution Of Life Histories And Phenotypic Plasticity Across Environmental Gradients In Daphnia Sp., Michelle Renee Swan Packer Aug 2020

The Evolution Of Life Histories And Phenotypic Plasticity Across Environmental Gradients In Daphnia Sp., Michelle Renee Swan Packer

Biology Dissertations - Archive

Understanding how environmentally-induced variation ultimately leads to speciation is a main component of evolutionary ecology. This dissertation uses Daphnia in experimental and comparative studies to address several theoretical questions concerning the role of phenotypic plasticity in the evolutionary process. Specifically, I explore novel environmental factors which induce plasticity and investigate the plastic response across systems to determine general hypotheses for understanding the mechanisms which may be involved. Additionally, this dissertation provides empirical results which add to the body of research investigating the transition between environmentally induced phenotypes and genetic adaptation. The results of this body of work show that ancestral …


Fundamentals Of Biology Bio 110, Michael Cerbo Jul 2020

Fundamentals Of Biology Bio 110, Michael Cerbo

Library Impact Statements

No abstract provided.


The Development Of An H1 Embryonic Stem Cell Line To Study The Role Of The Oncogenes Lmo1 And Mycn In Human Neuroblastoma Formation, Vincent Quiroz Jun 2020

The Development Of An H1 Embryonic Stem Cell Line To Study The Role Of The Oncogenes Lmo1 And Mycn In Human Neuroblastoma Formation, Vincent Quiroz

Electronic Theses, Projects, and Dissertations

Neuroblastoma (NB) is an extracranial tumor that affects the nervous system and accounts for approximately 650 – 800 cases diagnosed per year in children under the age of 5 (www.cancer.org/cancer/neuroblastoma/about/key-statistics.html). NB occurs at a relatively rare rate of 10.2 per million children under 15 years old but accounts for 12-15% of pediatric cancer death because patients with high-risk NB (HRNB) have 5-year survival rates between 40-50%(Brodeur, 2003; Park et al. 2010). Developmental biology research has recognized neural crest cells (NCC) as the progenitor cells of NB, as tumors form in the trunk NC derived sympathetic nervous system (Dupin, 2013; Simões-Costa …


Upcoming: Coming Spring 2018: Colby On Climate, Colby College May 2020

Upcoming: Coming Spring 2018: Colby On Climate, Colby College

Colby Magazine

No abstract provided.


A Review Of Plant-Soil Feedbacks And Their Importance For Palouse Prairie Restoration And Management, Rachael Sv Pentico May 2020

A Review Of Plant-Soil Feedbacks And Their Importance For Palouse Prairie Restoration And Management, Rachael Sv Pentico

2020 Symposium Posters

A plant-soil feedback (PSF) is the process in which plants alter both the biotic and abiotic characteristics of the soil they grow in. These changes in the soil composition alter which plants can grow and survive there in the future. Negative PSFs occur when plants struggle to grow in soil that was previously inhabited, due to a buildup of soil pathogens. Positive PSFs, however, provide benefits to the plants due to an abundance of soil microbes, such as AMF. Understanding the effects that PSFs have on plant communities and dynamics could be vital for restoring damaged ecosystems, like the Palouse …


Population Genetics Of A Recent Range Expansion By The Southern Pine Beetle, Dendroctonus Frontalis, Into The Northeastern United States, Megan Stubbs May 2020

Population Genetics Of A Recent Range Expansion By The Southern Pine Beetle, Dendroctonus Frontalis, Into The Northeastern United States, Megan Stubbs

Honors Theses

Population genetics as a field of study aims to determine the genetic variation among individuals in a population, and differences among populations. Certain population genetic analyses can provide such information and be used to better understand the biological aspects to a species’ expansion beyond its native range. The southern pine beetle (SPB), Dendroctonus frontalis, has become an invasive pest to pine forests in northeastern United States with its recent range expansion. Nine microsatellite loci were first developed and then used in analyses. To determine what the genetic variation is among individuals in SPB populations across its entire range, including …


Seminar In Biological Sciences Bio 228, Michael Cerbo May 2020

Seminar In Biological Sciences Bio 228, Michael Cerbo

Library Impact Statements

No abstract provided.


A Genomic Analysis Of Bobcat Populations In North America With A Comparison To The Canada Lynx: An Assessment Of Local Adaptation To Unique Ecoregions And Phylogeography, Jennifer C. Broderick May 2020

A Genomic Analysis Of Bobcat Populations In North America With A Comparison To The Canada Lynx: An Assessment Of Local Adaptation To Unique Ecoregions And Phylogeography, Jennifer C. Broderick

Electronic Theses and Dissertations

Bobcats (Lynx rufus) are an ecologically and genetically diverse species with a large contiguous range throughout North America. The species not only has a wide array of phenotypic variation compared to other mammals, but shows marked adaptability across ecozones with differing ecological influences. It is these various selective pressures in distinctive parts of the continent that have likely led to localized adaptations within the bobcat metapopulations. The species is also marked by its ability to maintain connectivity and populations in anthropogenically developed areas, an advantage it has over other felids, including its close relative the Canada lynx ( …


An Investigation Of The Impacts Of Traditional, Virtual, And Hybrid Biological Laboratories On College Students’ Achievement And Motivation To Learn Biology, Shavonda Jackson May 2020

An Investigation Of The Impacts Of Traditional, Virtual, And Hybrid Biological Laboratories On College Students’ Achievement And Motivation To Learn Biology, Shavonda Jackson

Dissertations

Virtual courses function in a different manner than traditional courses, therefore they require teaching methods and assessment techniques geared specifically to maximize this learning experience. Internet-based learning and distance-education are no longer new concepts in the science field. Because of this, many collegiate biology programs have created courses that can be taken virtual or hybrid. A number of experimental studies have had great influence in terms of the effects and impacts of educational technology in relation to virtual laboratories.

However, not many studies emphasize the impact of hybrid laboratories on student achievement or assess students’ motivation to learn in a …


A Comparison Of Egg Desiccation Tolerance And Development Under Different Temperatures For Three Common Aedes Mosquitoes, Shelby A. Hosch May 2020

A Comparison Of Egg Desiccation Tolerance And Development Under Different Temperatures For Three Common Aedes Mosquitoes, Shelby A. Hosch

Honors Theses

With the rise in global temperatures, invasive mosquito species like Aedes albopictus may be able to reach regions that were previously inhospitable to these species. Therefore, if A. albopictus were to potentially reach Puerto Rico, it would come into contact with the species of Aedes aegypti and Aedes mediovittatus in local containers, and it is unclear how the tropical temperatures and precipitation patterns would affect the co-occurrence of these three species. Egg desiccation and temperature dependent growth among the species were measured to test how these species hatched and developed during different humidity and temperature. It was hypothesized that there …


Investigating The Effects Of Temperature On Lesser Celandine, Regina Bellian Apr 2020

Investigating The Effects Of Temperature On Lesser Celandine, Regina Bellian

The Downtown Review: An Interdisciplinary Journal Written and Peer-Reviewed by Mandel Honors College Students at Cleveland State University

This paper explores invasive species Ficaria verna (Lesser celandine) and the effects of temperature on its growth. Trials were completed with two treatments, 13OC cold temperature and 20OC ambient temperature. Germinated bulbils of Lesser celandine were planted on February 15, 2017 and placed in their respective growing chambers. The plants were watered weekly and monitored for growth until harvest on March 29, 2017. Upon harvest, the plants’ height, largest leaf diameter and biomass were measured after extraction from soil and the removal of the leftover soil debris. Average height was found to be 11.66cm for the cold treatment and 5.14cm …


Yeast Bxi1p/Ybh3p Is A Ph-Sensitive Calcium Channel In Escherichia Coli., Amanda Raffa, John Kalhorn Apr 2020

Yeast Bxi1p/Ybh3p Is A Ph-Sensitive Calcium Channel In Escherichia Coli., Amanda Raffa, John Kalhorn

Biology Student Scholarship

Amanda Raffa ’21
Major: Biology

John Kalhorn ’21
Major: Biology

Faculty Mentor: Fr. Nicanor Austriaco, Biology


39 And Me: The Evolution Of Dogs Through The Study Of Genomics, Lauren Flynn, Kathleen Kuhl, Jordan Pagliuca, Megan Russel Apr 2020

39 And Me: The Evolution Of Dogs Through The Study Of Genomics, Lauren Flynn, Kathleen Kuhl, Jordan Pagliuca, Megan Russel

Biology Student Scholarship

Lauren Flynn ’21
Major: Biology and Mathematics

Jordan Pagliuca ’21
Major: Biology

Kathleen Kuhl ’22
Major: Biology

Megan Russell ’20
Major: Biology

Faculty Mentor: Dr. Elisabeth Arévalo, Biology

Our lab is interested in utilizing the dog model to explore the relationship between genes, evolution, and physical traits. The human selection and manipulation of different desirable traits in dogs has led to mutations that create the unique traits and diversity of breeds. Our lab uses different molecular methods to assess genetic mutations and different inheritable traits ranging from physical characteristics to disease in a variety of dog breeds. Statistical analysis and …


Autophagy And Lipid Metabolism In C.Elegans, Cristina De Corral, Samantha Otalvaro Apr 2020

Autophagy And Lipid Metabolism In C.Elegans, Cristina De Corral, Samantha Otalvaro

Biology Student Scholarship

Cristina de Corral ’22
Major: Biology

Samantha Otalvaro ’22
Major: Biology

Faculty Mentor: Dr. Melissa Silvestrini, Biology

The synthesis, storage, delivery and breakdown of lipids in the cell is crucial for organismal homeostasis. Dysfunction in lipid metabolism can lead to a variety of pathologies including diabetes, heart disease, and even neurodegenerative disorders such as Parkinson’s. One common link between these metabolic diseases is the cellular recycling process of autophagy. Autophagy plays a complex role in lipid metabolism as it is required for both lipid storage and breakdown. In C. elegans, loss of autophagy during development impairs production of neutral lipids. …


In Vitro Assessment Of Acute Neuro-Inflammation In A Model Of The Blood Brain Barrier, Cassandra Phillips, Dak Ojuka, Ramon G. Ortega-Alvarez, Anne-Deyssa Victor, Kathryn Fama Apr 2020

In Vitro Assessment Of Acute Neuro-Inflammation In A Model Of The Blood Brain Barrier, Cassandra Phillips, Dak Ojuka, Ramon G. Ortega-Alvarez, Anne-Deyssa Victor, Kathryn Fama

Biology Student Scholarship

Cassandra Phillips ’20
Major: Biology and Psychology

Dak Ojuka '20
Major: Biology Minor: Business and Innovation

Anne-Deyssa Victor '21
Major: Biology

Ramon G. Ortega-Alvarez ’20
Major: Biology

Kathryn Fama ’21
Major: Biology

Faculty Mentor: Dr. Charles Toth, Biology

The purpose of this experiment was to develop an in vitro model of the blood brain barrier that incorporated brain endothelial microvascular cells (BMEC) and co-cultures composed of neurons, astrocytes, and macrophages. All cell types were derived from human induced pluripotent stem cells. A transendothelial electrical resistance (TEER) assay and immunofluorescence were used to evaluate barrier function. In addition, the model was …


Modeling Parkinson’S Disease In The Budding Yeast, Saccharomyces Cerevisiae, Yuri Takenaka Apr 2020

Modeling Parkinson’S Disease In The Budding Yeast, Saccharomyces Cerevisiae, Yuri Takenaka

Biology Student Scholarship

Major: Biology and Mathematics
Faculty Mentor: Fr. Nicanor Austriaco O.P., Biology

Parkinson’s Disease (PD) is the second most common, incurable neurodegenerative disorder worldwide. PD patients have accumulations of abnormal proteins called Lewy Bodies (LBs) within their neurons that trigger cell death. Damaged and dead neurons lead to decline in dopamine levels, triggering the symptoms of Parkinson’s such as muscle stiffness, tremors, and slowed movement. Numerous studies have shown that the human protein, alpha-synuclein and Tau, are two major components of Lewy Bodies. To study the relationship between protein aggregation and cell death, I have created a system to co-overexpress human …


Distribution Of The Cold Water Coral Astrangia In The Waters Of Narrangansett Bay, Jared Getgano, Sarah Ramsaran, Victoria Hartley, Noah Mina Apr 2020

Distribution Of The Cold Water Coral Astrangia In The Waters Of Narrangansett Bay, Jared Getgano, Sarah Ramsaran, Victoria Hartley, Noah Mina

Biology Student Scholarship

No abstract provided.


Drosophila Models Of Neurodegenerative Diseases, Ella Clifford, Jackson Diltz, Emily Teixeira Apr 2020

Drosophila Models Of Neurodegenerative Diseases, Ella Clifford, Jackson Diltz, Emily Teixeira

Biology Student Scholarship

Ella Clifford ’20
Major: Biology and Psychology

Jackson Diltz ’22
Major: Biology

Emily Teixeira ’22
Major: Biology

We are working to determine if there are structural differences in the brains of flies modeling neurodegenerative diseases such as Frontotemporal Dementia and Alzheimer’s Disease in comparison to wild type flies. Our project is a complement to another study our lab is conducting on the metabolic activity of fruit fly models of neurodegenerative diseases. By analyzing cell size, cell pattern, and number of cells, we want to determine if the functional differences found in the metabolic study are mirrored in the structure of …


Investigating Metabolic Reprogramming In Neurodegenerative Disease, Sidney Mackinnon, Samantha Nicodemus Apr 2020

Investigating Metabolic Reprogramming In Neurodegenerative Disease, Sidney Mackinnon, Samantha Nicodemus

Biology Student Scholarship

Sidney MacKinnon ’21
Major: Biology

Samantha Nicodemus ’20
Major: Biology and Psychology, Neuroscience Certificate

Faculty Mentor: Dr. Marla Tipping, Biology


Pmsf And Sfn Reduce Alpha-Synuclein Aggregation In A Yeast Model Of Parkinson’S Disease, Noah Kozub, Taylor Brysgel, Christopher Yerxa Apr 2020

Pmsf And Sfn Reduce Alpha-Synuclein Aggregation In A Yeast Model Of Parkinson’S Disease, Noah Kozub, Taylor Brysgel, Christopher Yerxa

Biology Student Scholarship

Noah Kozub ’22
Major: Biology

Faculty Mentor: Fr. Nicanor Austriaco O.P, Biology


Studying Cardiovascular Disease Using Human Stem Cell-Derived 3d Cardiomyocytes, Nicholas Dash, Veronica Bohl Apr 2020

Studying Cardiovascular Disease Using Human Stem Cell-Derived 3d Cardiomyocytes, Nicholas Dash, Veronica Bohl

Biology Student Scholarship

Veronica Bohl ’20
Major: Biology and Psychology, Neuroscience Certificate Program

Nicholas Dash ’20
Major: Biology

Faculty Mentor: Dr. Charles Toth, Biology

This experiment provides insight on how using metabolites derived naturally from the microbiome can influence cardiac inflammation.3D cardiomyocytes were derived from human induced pluripotent stem cells through the utilization of small molecules and growth factors. Quantitative PCR was performed to verify that the organoids expressed genes associated with cardiomyocyte cells. Primers for the genes FOXa2, TNNT2, MYH7, AHR, CACNA1, and KCNH2 were used for the qPCR, as these genes are expressed more prominently in cardiomyocyte cells than the undifferentiated …


There’S A New Species Of Thief Ant Hiding In The Pine Barrens Of Rhode Island, Justin Andries Apr 2020

There’S A New Species Of Thief Ant Hiding In The Pine Barrens Of Rhode Island, Justin Andries

Biology Student Scholarship

Major: Biology and Sociology
Faculty Mentor: Dr. James Waters, Biology

Ants are often missed underfoot and overlooked, but they are among the most ecologically dominant groups of animals on the planet. There are more than 200 species of ants which have been scientifically recorded in New England but samples from Rhode Island represent less than a percent of the overall survey of our regional taxa. To discover the species that are found in Rhode Island, we are engaged in a multi-year and multi-location effort to systematically trap and accurately identify the ant species found in diverse rural and urban habitats …


Cancer: The Role Of Bax Inhibitor In C. Elegans, Ibrahim Abaherah, Michael Bittner, Kevin Ly Apr 2020

Cancer: The Role Of Bax Inhibitor In C. Elegans, Ibrahim Abaherah, Michael Bittner, Kevin Ly

Biology Student Scholarship

Ibrahim Abaherah ’20
Major: Biology

Michael Bittner '21
Major: Biology

Kevin Ly '23
Major: Biology

Faculty Mentor: Dr. Melissa Silvestrini, Biology

Bax inhibitor-1 is an evolutionarily conserved regulator of apoptosis and ER stress in cells. Bax inhibitor-1 is regulated by IRE-1, a transmembrane protein in the ER that is responsible for detection of ER-induced stress and activation of downstream targets involved in the unfolded protein response (UPR) to maintain homeostasis. Our goal is to determine whether the C. elegans Bax inhibitor-1 homolog tmbi-4 is dependent on the IRE1 pathway in C. elegans. Our preliminary data in the lab suggest that …


Comparison Of Branching Allometry Between Ginkgo Biloba And Several Native Michigan Trees, Collin Fox, Noah Holkeboer Apr 2020

Comparison Of Branching Allometry Between Ginkgo Biloba And Several Native Michigan Trees, Collin Fox, Noah Holkeboer

Student Scholars Day Posters

Ginkgo biloba is the only extant species of the gymnospermous order Ginkgoales. Like angiosperms, ginkgo is deciduous with broad leaves and vessel tubes. However, unlike angiosperms, ginkgo possesses a long-shoot x short-shoot branching system, the latter producing most of the leaves, and open-dichotomous leaf venation. Given that branching reflects optimization of photosynthetic capture through structural support and hydraulic efficiency, we compared the degree to which these functions were optimized for ginkgo relative to three native species. DBH, neighbor density and size were measured in field and branch dimensions were measured from photographs and analyzed per Murray’s Law for hydraulic optimization …


The Effects Of A New Mutation In Lis1 And Its Potential Role In Autism Spectrum Disorder, John A. Slovensky Apr 2020

The Effects Of A New Mutation In Lis1 And Its Potential Role In Autism Spectrum Disorder, John A. Slovensky

Senior Theses

LIS1 is a protein, particularly concentrated in the brain, that is important in regulating the movement and transport capabilities of dynein. Dynein is protein that can move along pathways in the cell, carrying various cellular components and also helping brain cells migrate. These two proteins are crucial during the development of the nervous system, and mutations in them can lead to lissencephaly, a disorder in which the brain does not form properly. This disease causes patients to develop cognitive-motor defects and seizures that can lead to early death. While all previously identified mutations in LIS1 are known to cause lissencephaly, …


Using Stable Isotopes And Diet Analysis To Assess The Potential For Competition And Coexistence Among Coyotes (Canis Latransl, Red Foxes (Vulpes Vulpes), And Gray Foxes (Urocyon Cinereoargenteus) In Maine, Henry M. Masters Apr 2020

Using Stable Isotopes And Diet Analysis To Assess The Potential For Competition And Coexistence Among Coyotes (Canis Latransl, Red Foxes (Vulpes Vulpes), And Gray Foxes (Urocyon Cinereoargenteus) In Maine, Henry M. Masters

Student Scholarship

When two species compete for food, one species typically outcompetes the other. Subordinate species can alleviate costs of competition by reducing diet overlap, promoting coexistence. Non-native coyotes (Canis latrans) and historically native gray foxes (Urocyon cineroargenteus) have expanded their range in Maine and may compete with native red foxes (Vulpes vulpes). To investigate competition, I analyzed stable isotopes and stomach contents to determine if coyotes, red foxes, and gray foxes differed in use of anthropogenic foods and trophic position. I predicted that coyotes utilize anthropogenic foods the least (lowest δ13C), and red foxes utilize …


Thing 1 And Thing 2 Are In A New Zoo: Changes In Behavior Of Amur Tigers Following Introduction To John Ball Zoo, Caitlin Gerke, Faith Hensley Apr 2020

Thing 1 And Thing 2 Are In A New Zoo: Changes In Behavior Of Amur Tigers Following Introduction To John Ball Zoo, Caitlin Gerke, Faith Hensley

Student Scholars Day Posters

Animals alter their behavior in response to changes in their environment such as alterations to their enclosure, social group, or husbandry routine. In 2018, two related, young adult Amur tigers (Panthera tigris altaica) were transferred to the John Ball Zoo (JBZ). The male siblings were given access to a spacious, wooded outdoor enclosure (area = 920 m²). We used Zoomonitor in 2018 and 2019 to conduct focal-animal sampling of the two males. We recorded state behaviors in 30 sec intervals of scan sampling, and all occurrences of event behaviors, both during 30 min sampling sessions. Our study objective …


Teaching Natural And Artificial Selection In Production Agriculture, Madhav P. Nepal, Clayton W. Scott Mar 2020

Teaching Natural And Artificial Selection In Production Agriculture, Madhav P. Nepal, Clayton W. Scott

iLEARN Teaching Resources

In this lesson, students will learn how natural selection and artificial selection impact both production agriculture and biological sciences. A natural selection is a mechanism that favors heritable traits that increase species survival and reproduction. Artificial selection is a selective breeding, where humans select for desirable traits in agricultural products.


The Current State Of Reptiles South Aral Sea Region And Their Protection, M. Jumanov, G. A. Asenov, Ya. I. Ametov, I. M. Arepbaev Mar 2020

The Current State Of Reptiles South Aral Sea Region And Their Protection, M. Jumanov, G. A. Asenov, Ya. I. Ametov, I. M. Arepbaev

Karakalpak Scientific Journal

The article presents the materials of herpetological studies conducted in 2007-2018 in the South Aral region. The main work on the study of the species composition, distribution and counting of all reptile species and ecological features was carried out in three large ecosystems (North-Western Kyzyl Kum, Ustyurt and the lower reaches of the Amu Darya). The studies were carried out according to standard methods using point and route counts. In the works, generally accepted methods of zoological and environmental studies are used. As a result of the inventory, the authors identified the modern species composition and number of reptiles in …