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Correlation Between Auditory Brainstem Recordings And Morphology As Seen Through The Scanning Electron Microscope, M. Hultcrantz
Correlation Between Auditory Brainstem Recordings And Morphology As Seen Through The Scanning Electron Microscope, M. Hultcrantz
Scanning Microscopy
Pregnant CBA/CBA mice were exposed to 0.5, 1 and 2 Grey (Gy), (1 Gy = 100 rad) in single doses with whole body gamma-irradiation on the 12th, 13th and 16th gestational days, respectively. The animals were tested at an age of one month for vestibular and cochlear function. Thereafter the inner ears were analyzed with scanning electron microscopy. A morphological analysis with cytocochleograms was performed.
Morphological changes in the vestibular part showed gross malformations in the cristae ampullares. Hair cells of type I seemed to be more severely changed than hair cells type II. The macula utriculi also showed malformations …
Intracellular Water Distribution And Aging As Examined By X-Ray Microanalysis, Thomas Von Zglinicki
Intracellular Water Distribution And Aging As Examined By X-Ray Microanalysis, Thomas Von Zglinicki
Scanning Microscopy
The results reviewed here demonstrate that 1. the distribution of dry mass as observed in frozen-dried cryosections might be used as an unbiased measure of intracellular dry mass resp. water distributions in the tissue in vivo and 2. the well-known loss of water from cells during aging is solely due to a water loss from mitochondria without changes in the water content of all other components of the cell in the case of rat liver and heart muscle.
The reason for the water loss might be increased counter ion binding by membrane-bound enzymes due to decreased fluidity of the inner …