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Articles 1 - 9 of 9
Full-Text Articles in Bioinformatics
Mmappr2: An Improved Bioinformatics Approach To Find Novel Genes, Aiden Cardall, Jonathon T. Hill, Kyle Johnsen, Connor Ward, Maliha Tasnim, Jared Taylor
Mmappr2: An Improved Bioinformatics Approach To Find Novel Genes, Aiden Cardall, Jonathon T. Hill, Kyle Johnsen, Connor Ward, Maliha Tasnim, Jared Taylor
Library/Life Sciences Undergraduate Poster Competition 2024
Introduction
• New genes are commonly found by randomly inducing mutations in model organisms.
• Mapping the mutations to the genome to find novel genes is difficult, time-consuming, and expensive.
• We created a bioinformatics program, MMAPPR, to automate this process.
• Here, we introduce a new algorithm, MMAPPR2, which requires little to no bioinformatics knowledge to use.
• MMAPPR2 makes several improvements that allow it to identify genes more rapidly and precisely.
• MMAPPR2 will aid the rapid identification of genes in a wide range of species and developmental systems.
Determining The Role Of Noncoding Insertion And Deletion Mutations In Lung Cancer, Zachary Everton, Matthew H. Bailey
Determining The Role Of Noncoding Insertion And Deletion Mutations In Lung Cancer, Zachary Everton, Matthew H. Bailey
Library/Life Sciences Undergraduate Poster Competition 2024
Background
● Cancer is a disease in which cells grow and divide at an uncontrolled rate and cause damage to surrounding tissue and is caused by mutations in the cells’ DNA.
● Though some cancer-causing mutations are inherited from parents, most cancer-causing mutations emerge over the course of a person’s life and are localized to the tumor. These localized mutations are also known as somatic mutations.
● The human genome is over 6.27 billion base pairs long and cannot be read from end to end; instead it is read in small pieces that are aligned to best-matching sequences in the …
Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia
Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia
Journal of Nonprofit Innovation
Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.
Imagine Doris, who is …
Survey Of Visual Opsin Evolution Across Caddisflies (Insecta: Trichoptera), Ashlynn Powell, Jacqueline Heckenhauer, Steffen Pauls, Paul Frandsen
Survey Of Visual Opsin Evolution Across Caddisflies (Insecta: Trichoptera), Ashlynn Powell, Jacqueline Heckenhauer, Steffen Pauls, Paul Frandsen
Library/Life Sciences Undergraduate Poster Competition 2022
Caddisflies are a highly diverse order of aquatic insects. As eggs, larvae, and pupae, they occupy freshwater habitats, while as adults, they are generally aerial and terrestrial1. Such varied environments call for a flexible and complex visual system. Visual systems are controlled by light-sensing molecules called opsins, which are categorized by the wavelength of light they are most sensitive to2. In insects, these categories are:
- Long wavelength (LW)
- Short wavelength (SW)
- Ultraviolet wavelength (UV)
Adaptive duplication of opsin genes is the primary mechanism of evolution that allows for greater visual capacity3. While opsins have …
Does Bathing After Sexual Assault Or Time Elapsed Have A Greater Effect On The Development Of Codis Eligible Dna Profiles?, Emily Black, Sam Payne, Julie Valentine, Leslie Miles
Does Bathing After Sexual Assault Or Time Elapsed Have A Greater Effect On The Development Of Codis Eligible Dna Profiles?, Emily Black, Sam Payne, Julie Valentine, Leslie Miles
Library/Life Sciences Undergraduate Poster Competition 2022
Which has a greater effect on the development of CODIS eligible DNA profiles from SAKs – bathing/showering status of the victim or time between the assault and examination?
Male And Female Victims Experience Different Types Of Sexual Assault, Carolyn Allen, Samuel Payne, Julie Valentine
Male And Female Victims Experience Different Types Of Sexual Assault, Carolyn Allen, Samuel Payne, Julie Valentine
Library/Life Sciences Undergraduate Poster Competition 2022
Intro:
- Sexual assault kits (SAKs) contain forensic evidence and are collected following an assault
- Most research on SAK processing has been done with combined male and female assaults
- 10% of victims are male
- There is lots of research on female victims, but very little research on male victims
Eeg As Successful Diagnostic Tool For Immune Effector Cell Associated Neurotoxicity Syndrome, Daniel Jones, Christine Eckhardt, Haoqi Sun, Ryan Tesh, Brandon Westover
Eeg As Successful Diagnostic Tool For Immune Effector Cell Associated Neurotoxicity Syndrome, Daniel Jones, Christine Eckhardt, Haoqi Sun, Ryan Tesh, Brandon Westover
Library/Life Sciences Undergraduate Poster Competition 2022
CAR T cell therapy was first proven effective in 20131 for the treatment of certain cancer s . However, its widespread adoption is still hindered by side effects like immune effector cell associated neurotoxicity syndrome (ICANS). Current research aims to better predict, diagnose, and treat ICANS so that CAR T cell therapy can be more widely applied. Although prior studies have attempted to identify an objective biomarker of ICANS2 , current practice relies on clinical assessment to diagnose ICANS. We hypothesize that qualitative features of the EEG may be utilized to develop a physiological grading system of the …
Using Non Stem-Cells To Understand Early Tumor Growth, Jake Hogan, Heiko Enderling, Joel Brown, Robert A. Gatenby
Using Non Stem-Cells To Understand Early Tumor Growth, Jake Hogan, Heiko Enderling, Joel Brown, Robert A. Gatenby
Library/Life Sciences Undergraduate Poster Competition 2018
Tumors of similar size and shape can exhibit different responses to the same treatment. Targeted therapy aims to better treat these tumors by classifying them according to genotypic traits. A better understanding of how tumor traits such as non-stem cells influence tumor growth could improve targeted therapy. We hypothesize that the production of non-stem cells may aid tumor growth in avascular tumors (tumors lacking blood vessels).
Genome-Wide Association Study Of Prolactin In Cerebrospinal Fluid And Plasma, Lorna Sheradyn Hamilton, Dr. John Kauwe
Genome-Wide Association Study Of Prolactin In Cerebrospinal Fluid And Plasma, Lorna Sheradyn Hamilton, Dr. John Kauwe
Journal of Undergraduate Research
Prolactin is the major hormone involved in milk lactation for pregnant women and has been discovered to play a role in a variety of biological functions. Several other functions include the immune system, reproductive system, maternal behavior, insulin production, and stimulating neurogenesis.1 2 Using prolactin levels from both cerebrospinal fluid and blood plasma from nearly 500 individuals, we will be able to conduct a genome-wide association study to identify single-nucleotide polymorphisms (SNPs), which will lead to a better understanding of what genes are playing a significant role in prolactin’s production and regulation.