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Full-Text Articles in Biodiversity

Genomic Plasticity And Rapid Host Switching Can Promote The Evolution Of Generalism: A Case Study In The Zoonotic Pathogen Campylobacter, Dan J. Woodcock, Peter Krusche, Norval J. C. Strachan, Ken J. Forbes, Frederick M. Cohan, Guillaume Meric, Samuel K. Sheppard Dec 2016

Genomic Plasticity And Rapid Host Switching Can Promote The Evolution Of Generalism: A Case Study In The Zoonotic Pathogen Campylobacter, Dan J. Woodcock, Peter Krusche, Norval J. C. Strachan, Ken J. Forbes, Frederick M. Cohan, Guillaume Meric, Samuel K. Sheppard

Frederick M. Cohan

Horizontal gene transfer accelerates bacterial adaptation to novel environments, allowing selection to act on genes that have evolved in multiple genetic backgrounds. This can lead to ecological specialization. However, little is known about how zoonotic bacteria maintain the ability to colonize multiple hosts whilst competing with specialists in the same niche. Here we develop a stochastic evolutionary model and show how genetic transfer of host segregating alleles, distributed as predicted for niche specifying genes, and the opportunity for host transition could interact to promote the emergence of host generalist lineages of the zoonotic bacterium Campylobacter. Using a modelling approach …


The Molecular Dimension Of Microbial Species: 3. Comparative Genomics Of Synechococcus Strains With Different Light Responses And In Situ Diel Transcription Patterns Of Associated Putative Ecotypes In The Mushroom Spring Microbial Mat, Millie Olsen, Shane Nowack, Jason Wood, Eric Becraft, Kurt Labutti, Anna Lipzen, Joel Martin, Wendy Shackwitz, Douglas Rusch, Frederick Cohan, Donald Bryant, David Ward Jan 2015

The Molecular Dimension Of Microbial Species: 3. Comparative Genomics Of Synechococcus Strains With Different Light Responses And In Situ Diel Transcription Patterns Of Associated Putative Ecotypes In The Mushroom Spring Microbial Mat, Millie Olsen, Shane Nowack, Jason Wood, Eric Becraft, Kurt Labutti, Anna Lipzen, Joel Martin, Wendy Shackwitz, Douglas Rusch, Frederick Cohan, Donald Bryant, David Ward

Frederick M. Cohan

Genomes were obtained for three closely related strains of Synechococcus that are representative of putative ecotypes that predominate at different depths in the 1 mm-thick, upper-green layer in the 60°C mat of Mushroom Spring, Yellowstone National Park, and exhibit different light adaptation and acclimation responses. The genomes were compared to the published genome of a previously obtained, closely related strain from a neighboring spring, and differences in both gene content and orthologous gene alleles between high-light-adapted and low-light-adapted strains were identified. Evidence of genetic differences that relate to adaptation to light intensity and/or quality, CO2 uptake, nitrogen metabolism, organic carbon …


The Molecular Dimension Of Microbial Species: 1. Ecological Distinctions Among, And Homogeneity Within, Putative Ecotypes Of Synechococcus Inhabiting The Cyanobacterial Mat Of Mushroomspring,Yellowstone National Park, Eric D. Becraft, Jason M. Wood, Douglas B. Rusch, Michael Kuhl, Sheila Jensen, Donald A. Bryant, David W. Roberts, Frederick M. Cohan, David M. Ward Dec 2014

The Molecular Dimension Of Microbial Species: 1. Ecological Distinctions Among, And Homogeneity Within, Putative Ecotypes Of Synechococcus Inhabiting The Cyanobacterial Mat Of Mushroomspring,Yellowstone National Park, Eric D. Becraft, Jason M. Wood, Douglas B. Rusch, Michael Kuhl, Sheila Jensen, Donald A. Bryant, David W. Roberts, Frederick M. Cohan, David M. Ward

Frederick M. Cohan

Based on the Stable Ecotype Model, evolution leads to the divergence of ecologically distinct populations (e.g., with different niches and/or behaviors) of ecologically interchangeable membership. In this study, pyrosequencing was used to provide deep sequence coverage of Synechococcus psaA genes (encoding a photosystem I reaction center protein subunit) and transcripts over a large number of habitat types in the Mushroom Spring microbial mat. Putative ecological species (putative ecotypes), which were predicted by an evolutionary simulation based on the Stable Ecotype Model (Ecotype Simulation), exhibited distinct distributions relative to temperature-defined positions in the effluent channel and vertical position in the upper …


Accuracy And Efficiency Of Algorithms For The Demarcation Of Bacterial Ecotypes From Dna Sequence Data, Juan Carlos Francisco, Frederick M. Cohan, Danny Krizanc Dec 2013

Accuracy And Efficiency Of Algorithms For The Demarcation Of Bacterial Ecotypes From Dna Sequence Data, Juan Carlos Francisco, Frederick M. Cohan, Danny Krizanc

Frederick M. Cohan

Identification of closely related, ecologically distinct populations of bacteria would benefit microbiologists working in many fields including systematics, epidemiology and biotechnology. Several laboratories have recently developed algorithms aimed at demarcating such ‘ecotypes’. We examine the ability of four of these algorithms to correctly identify ecotypes from sequence data. We tested the algorithms on synthetic sequences, with known history and habitat associations, generated under the stable ecotype model and on data from Bacillus strains isolated from Death Valley where previous work has confirmed the existence of multiple ecotypes. We found that one of the algorithms (ecotype simulation) performs significantly better than …


Science Needs More Moneyball, Frederick Cohan Jan 2012

Science Needs More Moneyball, Frederick Cohan

Frederick M. Cohan

No abstract provided.


Demarcation Of Bacterial Ecotypes From Dna Sequence Data: A Comparative Analysis Of Four Algorithms, Juan Francisco, Frederick Cohan, Danny Krizanc Jan 2012

Demarcation Of Bacterial Ecotypes From Dna Sequence Data: A Comparative Analysis Of Four Algorithms, Juan Francisco, Frederick Cohan, Danny Krizanc

Frederick M. Cohan

No abstract provided.


Prokaryotic Sex: Eukaryote-Like Qualities Of Recombination In An Archaean Lineage, Frederick Cohan, Stephanie Aracena Jan 2012

Prokaryotic Sex: Eukaryote-Like Qualities Of Recombination In An Archaean Lineage, Frederick Cohan, Stephanie Aracena

Frederick M. Cohan

No abstract provided.


Diversity Of Bacteria And Archaea In Hypersaline Sediment From Death Valley National Park, California, J.-S. Kim, M. Makama, J. Petito, N.-H. Park, Frederick M. Cohan, R. S. Dungan Dec 2011

Diversity Of Bacteria And Archaea In Hypersaline Sediment From Death Valley National Park, California, J.-S. Kim, M. Makama, J. Petito, N.-H. Park, Frederick M. Cohan, R. S. Dungan

Frederick M. Cohan

No abstract provided.


The Variable Subdomain Of Escherichia Coli Seca Functions To Regulate Seca Atpase Activity And Adp Release, Sanchaita Das, Lorry M. Grady, Jennifer Michtavy, Yayan Zhou, Frederick M. Cohan, Manju M. Hingorani, Donald B. Oliver Dec 2011

The Variable Subdomain Of Escherichia Coli Seca Functions To Regulate Seca Atpase Activity And Adp Release, Sanchaita Das, Lorry M. Grady, Jennifer Michtavy, Yayan Zhou, Frederick M. Cohan, Manju M. Hingorani, Donald B. Oliver

Frederick M. Cohan

No abstract provided.


Diversity Of Bacteria And Archaea In Hypersaline Sediment From Death Valley National Park, California, J.-S. Kim, M. Makama, J. Petito, N.-H. Park, Frederick M. Cohan, R. S. Dungan Dec 2011

Diversity Of Bacteria And Archaea In Hypersaline Sediment From Death Valley National Park, California, J.-S. Kim, M. Makama, J. Petito, N.-H. Park, Frederick M. Cohan, R. S. Dungan

Frederick M. Cohan

No abstract provided.


Comment On "Population Genomics Of Early Events In The Ecological Differentiation Of Bacteria", Sarah M. Kopac, Frederick M. Cohan Dec 2011

Comment On "Population Genomics Of Early Events In The Ecological Differentiation Of Bacteria", Sarah M. Kopac, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Koufax's Perfect Game--The Tale Of The Data, Frederick Cohan Sep 2011

Koufax's Perfect Game--The Tale Of The Data, Frederick Cohan

Frederick M. Cohan

No abstract provided.


Fine-Scale Distribution Patterns Of Synechococcus Ecological Diversity In The Microbial Mat Of Mushroom Spring, Yellowstone National Park, Eric Becraft, Frederick Cohan, Michael Kuhl, Sheila Jensen, David Ward Jan 2011

Fine-Scale Distribution Patterns Of Synechococcus Ecological Diversity In The Microbial Mat Of Mushroom Spring, Yellowstone National Park, Eric Becraft, Frederick Cohan, Michael Kuhl, Sheila Jensen, David Ward

Frederick M. Cohan

No abstract provided.


Q & A: Frederick Cohan, Frederick M. Cohan Dec 2010

Q & A: Frederick Cohan, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Influence Of Molecular Resolution On Sequence-Based Discovery Of Ecological Diversity Among Synechococcus Populations In An Alkaline Siliceous Hot Spring Microbial Mat, Melanie C. Melendrez, R. K. Lange, Frederick M. Cohan, David M. Ward Dec 2010

Influence Of Molecular Resolution On Sequence-Based Discovery Of Ecological Diversity Among Synechococcus Populations In An Alkaline Siliceous Hot Spring Microbial Mat, Melanie C. Melendrez, R. K. Lange, Frederick M. Cohan, David M. Ward

Frederick M. Cohan

No abstract provided.


Are Species Cohesive?—A View From Bacteriology, Frederick M. Cohan Dec 2010

Are Species Cohesive?—A View From Bacteriology, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


A Theory-Based Pragmatism For Discovering And Classifying Newly Divergent Bacterial Species, Sarah Kopac, Frederick M. Cohan Dec 2010

A Theory-Based Pragmatism For Discovering And Classifying Newly Divergent Bacterial Species, Sarah Kopac, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Q&A: Frederick Cohan Dec 2010

Q&A: Frederick Cohan

Frederick M. Cohan

No abstract provided.


Synthetic Genome: Now That We’Re Creators, What Should We Create?, Frederick M. Cohan Dec 2009

Synthetic Genome: Now That We’Re Creators, What Should We Create?, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


The Ecology Of Speciation In Bacillus, Nora Connor, Johannes Sikorski, Alejandro P. Rooney, Sarah Kopac, Alexander F. Koeppel, Andrew Burger, Scott G. Cole, Elizabeth B. Perry, Danny Krizanc, Nicholas C. Field, Michele Slaton, Frederick M. Cohan Dec 2009

The Ecology Of Speciation In Bacillus, Nora Connor, Johannes Sikorski, Alejandro P. Rooney, Sarah Kopac, Alexander F. Koeppel, Andrew Burger, Scott G. Cole, Elizabeth B. Perry, Danny Krizanc, Nicholas C. Field, Michele Slaton, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Tracking Bacterial Responses To Global Warming With An Ecotype-Based Systematics, Frederick M. Cohan Dec 2008

Tracking Bacterial Responses To Global Warming With An Ecotype-Based Systematics, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Identifying The Fundamental Units Of Bacterial Diversity: A Paradigm Shift To Incorporate Ecology Into Bacterial Systematics, A. F. Koeppel, E. B. Perry, J. Sikorski, A. Warner, D. M. Ward, A. P. Rooney, E. Brambilla, N. Connor, E. Nevo, R. M. Ratcliff, Frederick M. Cohan Dec 2007

Identifying The Fundamental Units Of Bacterial Diversity: A Paradigm Shift To Incorporate Ecology Into Bacterial Systematics, A. F. Koeppel, E. B. Perry, J. Sikorski, A. Warner, D. M. Ward, A. P. Rooney, E. Brambilla, N. Connor, E. Nevo, R. M. Ratcliff, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Toward A Conceptual And Operational Union Of Bacterial Systematics, Ecology, And Evolution, Frederick M. Cohan Dec 2005

Toward A Conceptual And Operational Union Of Bacterial Systematics, Ecology, And Evolution, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Cyanobacterial Ecotypes In The Microbial Mat Community Of Mushroom Spring (Yellowstone National Park, Wyoming) As Species-Like Units Linking Microbial Community Composition, Structure And Function, D. M. Ward, M. M. Bateson, M. J. Ferris, M. Kuhl, A. Wieland, A. Koeppel, Frederick M. Cohan Dec 2005

Cyanobacterial Ecotypes In The Microbial Mat Community Of Mushroom Spring (Yellowstone National Park, Wyoming) As Species-Like Units Linking Microbial Community Composition, Structure And Function, D. M. Ward, M. M. Bateson, M. J. Ferris, M. Kuhl, A. Wieland, A. Koeppel, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Periodic Selection And Ecological Diversity In Bacteria, Frederick Cohan Jan 2005

Periodic Selection And Ecological Diversity In Bacteria, Frederick Cohan

Frederick M. Cohan

No abstract provided.


Microbial Diversity In Hot Spring Cyanobacterial Mats: Pattern And Prediction, Frederick M. Cohan, D. M. Ward Dec 2004

Microbial Diversity In Hot Spring Cyanobacterial Mats: Pattern And Prediction, Frederick M. Cohan, D. M. Ward

Frederick M. Cohan

No abstract provided.


Which Species Concept For Bacteria?—An E-Debate, S. Godreuil, Frederick M. Cohan, H. Shah, M. Tibayrenc Dec 2004

Which Species Concept For Bacteria?—An E-Debate, S. Godreuil, Frederick M. Cohan, H. Shah, M. Tibayrenc

Frederick M. Cohan

No abstract provided.


Concepts Of Bacterial Biodiversity For The Age Of Genomics, Frederick M. Cohan Dec 2003

Concepts Of Bacterial Biodiversity For The Age Of Genomics, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


Gradual Evolution In Bacteria: Evidence From Bacillus Systematics, M. Feldgarden, N. Byrd, Frederick M. Cohan Dec 2002

Gradual Evolution In Bacteria: Evidence From Bacillus Systematics, M. Feldgarden, N. Byrd, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.


What Are Bacterial Species?, Frederick M. Cohan Dec 2001

What Are Bacterial Species?, Frederick M. Cohan

Frederick M. Cohan

No abstract provided.