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Articles 1 - 4 of 4
Full-Text Articles in Other Biochemistry, Biophysics, and Structural Biology
Cifa And Cifb Expression In Response To Piwi And Aub Knockdown In Jw18 D. Melanogaster Cells, Julieta Alarcon
Cifa And Cifb Expression In Response To Piwi And Aub Knockdown In Jw18 D. Melanogaster Cells, Julieta Alarcon
Posters - 2024
Wolbachia is an intracellular bacterium that is known for inducing cytoplasmic incompatibility (CI) in its Drosophila melanogaster hosts. CI is characterized by embryonic death when males that express cifA and cifB genes mate with unaffected females (Shropshire, Rosenberg, and Bordenstein 2020). PIWI proteins play important roles such as germline determination, spermiogenesis, and transposon silencing (Thomson and Lin 2009). Previous studies have shown that Piwi expression decreases in a developmental window called the “Piwiless pocket” or Pilp. When Aub is depleted in the Pilp, then Piwi expression increases (Théron et al. 2018). We will determine if Piwi and Aub FANA ASO …
Expression And Purification Of Domain 1 Of The Cards Toxin, Dylan Andrews, Allison Woods, Ahmad Galaleldeen
Expression And Purification Of Domain 1 Of The Cards Toxin, Dylan Andrews, Allison Woods, Ahmad Galaleldeen
Posters - 2024
Mycoplasma pneumoniae (Mp) is an atypical bacterium that is linked to various respiratory diseases such as walking pneumonia and asthma. Upon infection, Mp produces a 591-aa virulence factor known as Community Acquired Respiratory Distress Syndrome Toxin (CARDS TX). The crystal structure of this 591-aa cytotoxin reveals a triangular molecule comprised of an N-terminal ADP-ribosylating domain and a Cterminal tandem β-trefoil domain that is responsible for vacuolation of the host’s cells. Based on structural and sequence homology to other ADP ribosylating toxins, the NAD+ binding site has been predicted, yet none of the published structures of the CARDS toxin contain NAD+. …
Annual Faculty Research Symposium 2022, Oakwood University
Annual Faculty Research Symposium 2022, Oakwood University
Proceedings
No abstract provided.
Open Neuroscience Initiative, Austin Lim
Open Neuroscience Initiative, Austin Lim
College of Science and Health Full Text Publications
The Open Neuroscience Initiative is a free-to-use textbook
This project began as a means to overcoming the financial burden that face undergraduate neuroscience students when buying textbooks. By compiling and writing a completely free-to-access textbook that covers the foundations of a typical college introduction to neuroscience course, students would have one less obstacle to overcome in their educational career, allowing them to focus their valuable time and attention on learning rather than finances. To make this project a reality, I began with a humble tweet in May 2019 that managed to gain a tiny bit of traction among the neuroscience …