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Full-Text Articles in Biochemistry
Missense Mutations In The Gamma Crystallins And Mechanisms Of Lens Opacity, Wenjuan Hou
Missense Mutations In The Gamma Crystallins And Mechanisms Of Lens Opacity, Wenjuan Hou
Legacy Theses & Dissertations (2009 - 2024)
Cataract, or clouding of the ocular lens, among the most common types of eye diseases, is the leading cause of blindness worldwide. With the opacity or clouding of the lens, light incident on the lens is scattered rather than being transmitted and is thus prevented from focusing on the retina. The lens becomes cataractous due to a large number of reasons, among which aging and genetic mutations are two of the most common factors. Clouding of the center of the lens or nuclear opacity, is the most frequently observed type of age-onset cataract, as well as inherited, congenital cataract [1, …