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Full-Text Articles in Biochemistry
Structural And Biochemical Characterization Of The Frequency-Interacting Rna Helicase Frh, Jacqueline M. Johnson
Structural And Biochemical Characterization Of The Frequency-Interacting Rna Helicase Frh, Jacqueline M. Johnson
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Cells function through a variety of regulatory pathways intricately communicating with one another. These pathways ensure that cellular functions happen at the appropriate times and keep the natural balance within the cell. When pathways do not communicate appropriately, this can lead to disease states and cell death. Two such connected pathways in Neurospora crassa involve the regulation of RNA levels and the circadian rhythms essential for these cells to maintain homeostasis. These pathways are connected by a unique helicase called the Frequency-interacting RNA Helicase (FRH), named for its discovery with the frequency protein involved in the circadian oscillation of the …