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Full-Text Articles in Biochemistry
The Biological Function Of Hammerhead Rana Ribozyme In Human Genome, Ibtehal M. A. Awad
The Biological Function Of Hammerhead Rana Ribozyme In Human Genome, Ibtehal M. A. Awad
Theses
Hammerhead RNA [HHR] sequence originally found in viroids is also detected in many species. HHR are often found in introns of different genes ranging from prokaryotes to
eukaryotes. HHR can form specific tertiary structure that make specific region susceptible to cleavage. However, the role of the HHR is not clear in other life forms. This study aims to
Investigate the role of HHR in the intron 6 of (RECK) gene. Our study shows that when blocking the HHR sequence in the intron6, the production of RECK protein declines which may be due to the effect of HHR in splicing and …