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Biochemistry Commons

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Theses/Dissertations

2005

Physical Sciences and Mathematics

Pure sciences

Articles 1 - 2 of 2

Full-Text Articles in Biochemistry

Microcapsule Biosensors Based On Competitive Binding And Fluorescence Resonance Energy Transfer Assays, Swetha Chinnayelka Oct 2005

Microcapsule Biosensors Based On Competitive Binding And Fluorescence Resonance Energy Transfer Assays, Swetha Chinnayelka

Doctoral Dissertations

Fluorescent sensing systems offer the potential for minimally invasive monitoring with implantable devices, but they require carrier technologies that provide suitable immobilization, accessibility, and biocompatibility while maintaining adequate response characteristics. Towards the development of this goal, a general design of a biosensor with the capability of detecting different metabolites was investigated. The approach is based on the encapsulation of a competitive binding assay in microcapsules and monitoring the changes in fluorescence resonance energy transfer (FRET) in the presence of analyte. To experimentally demonstrate this type of sensing system, glucose was chosen as the model target analyte. The design, fabrication, and …


Synthesis Of Novel Porphyrazines And Binding Studies To Dna Quadruplexes, Carlos Ramirez Jan 2005

Synthesis Of Novel Porphyrazines And Binding Studies To Dna Quadruplexes, Carlos Ramirez

Seton Hall University Dissertations and Theses (ETDs)

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