Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Biochemistry
Interactions Of Viral And Cellular Helicases, Megan Josephine Corby
Interactions Of Viral And Cellular Helicases, Megan Josephine Corby
Theses and Dissertations
The innate immune system is a part of the first line of defense against virus infection. An important subset of the innate immune system consists of a group of intracellular pattern recognition receptors (PRRs) which recognize conserved features of bacteria and viruses and initiate an interferon response. The RIG-I like receptors (RLRs) are PRRs that bind to RNA viruses (such as hepatitis c virus) and signal through the adaptor mitochondrial anti-viral signaling protein (MAVS).
Hepatitis C virus (HCV) is a small enveloped RNA virus that belongs to the flaviviridae family of viruses. HCV infects hepatocytes and can cause a persistent …