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Full-Text Articles in Biochemistry
Hydrogen/Deuterium Exchange Studies Of Protein And Non-Protein Amino Acids Using Electrospray Ionization Mass Spectrometry, Justine Victoria Arrington
Hydrogen/Deuterium Exchange Studies Of Protein And Non-Protein Amino Acids Using Electrospray Ionization Mass Spectrometry, Justine Victoria Arrington
Dissertations, Theses, and Masters Projects
No abstract provided.
Thermochemistry Of Amino Acids And Constrained Diamines, Erica Jane Tullo
Thermochemistry Of Amino Acids And Constrained Diamines, Erica Jane Tullo
Dissertations, Theses, and Masters Projects
The gas-phase proton affinities of several highly basic amino acids and diamines were determined using the extended kinetic method in an ESI-quadrupole ion trap instrument. The non-protein amino acid L-canavanine is structurally related to L-arginine with an oxygen substituted for the terminal methylene group of L-arginine and is highly toxic to humans. The proton affinity of L-arginine, a protein amino acid, was determined to be 1036 kJ mol -1, whereas the proton affinity of L-canavanine was determined to be 1005 kJ mol-1. Thus, substitution of an oxyguanidino group for the guanidine group in L-arginine results in a large decrease in …