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Biochemistry Commons™

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University at Albany, State University of New York

2013

Major histocompatibility complex

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Structural Biology Of The Receptor For Advanced Glycation End Products (Rage), Jing Xue Jan 2013

Structural Biology Of The Receptor For Advanced Glycation End Products (Rage), Jing Xue

Legacy Theses & Dissertations (2009 - 2024)

The receptor for advanced glycated end products (RAGE), due to its location in the major histocompatibility complex class III (MHC III) region, suggests its involvement in immune responses. Because RAGE has been linked to complications of diabetes and chronic inflammation, the severity of Alzheimer's disease and cancer, it's significant to understanding the biological mechanism of signal transduction of RAGE.

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