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Full-Text Articles in Biochemistry
Semaphorin-Induced Plasticity In The Nervous System Of The Cricket, Gryllus Bimaculatus, Alicia G. Edwards
Semaphorin-Induced Plasticity In The Nervous System Of The Cricket, Gryllus Bimaculatus, Alicia G. Edwards
Honors Projects
The adult auditory system of the cricket, Gryllus bimaculatus, exhibits a rare example of neuronal plasticity. Upon deafferentation, we observe medial dendrites that normally respect the midline of the PTG in the central nervous system sprouting across the boundary and forming synaptic connections with the contralateral auditory afferents. The Horch Lab has investigated key molecular factors that might play a causal role in this paradigm. Specifically, the protein Sema1a.2 comes from a guidance molecule family and has a role in developmental neuronal plasticity in other organisms. In this study, I explored the role of Sema1a.2 in the neuronal plasticity of …