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Full-Text Articles in Biochemistry
Crosstalk Between Rho-Family Gtpases At The Division Site During Cytokinesis, Emma Nicole Koory
Crosstalk Between Rho-Family Gtpases At The Division Site During Cytokinesis, Emma Nicole Koory
Chancellor’s Honors Program Projects
No abstract provided.
Cell Separation Delay And Membrane Trafficking Defects In Cdc42 Gap Mutants, Haylee Young
Cell Separation Delay And Membrane Trafficking Defects In Cdc42 Gap Mutants, Haylee Young
Chancellor’s Honors Program Projects
No abstract provided.
Regulation Of The Tubulin Homolog Ftsz In Escherichia Coli, Monika S. Buczek
Regulation Of The Tubulin Homolog Ftsz In Escherichia Coli, Monika S. Buczek
Dissertations, Theses, and Capstone Projects
Escherichia coli is a well-known pathogen, and importantly, a widely used model organism in all fields of biological sciences for cloning, protein purification, and as a model for Gram-negative bacterial species. And yet, researchers do not fully understand how this bacterium replicates and divides. Every year additional division proteins are discovered, which adds complexity to how we understand E. coli undergoes cell division. Due to their specific roles in cytokinesis, some of these proteins may be potential targets for development of antibacterials or bacteriostatics, which are much needed for fighting the current global antibacterial deficit. My thesis work focuses on …
Dissecting Molecular Pathways That Ensure Proper Chromosome Segregation And Cell Division, Anna Ye
Dissecting Molecular Pathways That Ensure Proper Chromosome Segregation And Cell Division, Anna Ye
Doctoral Dissertations
Equal segregation of the genome is a prerequisite for cell survival. During cell division the duplicated DNA is compacted into chromosomes and a multi-protein macrostructure, known as the kinetochore (Kt), is assembled on each copy of compacted DNA. Simultaneously, the mitotic spindle, which is made up of microtubules (MTs), is built to facilitate the equal distribution of the chromosomes between the resulting daughter cells. Kinetochores mediate the interaction between the MTs and the chromosomes, properly positioning them for segregation. To ensure that the DNA is equally divided in every cell division, cells have built a surveillance system to detect any …