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Full-Text Articles in Biochemistry
Accidental Poison: Analysis Of 1,4-Butanediol In A Popular Children's Arts And Crafts Toy, Christopher R. Dockery, John H. Shugart, Jonathan D. Parker, William J. Lawson
Accidental Poison: Analysis Of 1,4-Butanediol In A Popular Children's Arts And Crafts Toy, Christopher R. Dockery, John H. Shugart, Jonathan D. Parker, William J. Lawson
Faculty and Research Publications
A popular children's arts and crafts toy made international headlines when it was discovered that 1,4-butanediol had been substituted into some of its formulations. The chemical 1,4-butanediol rapidly converts to the date-rape drug g-hydroxybutyric acid (GHB) upon ingestion and resulted in the accidental poisoning of some children. In this experiment, students extract 1,4-butanediol from commercially available toy beads (or prepared simulations) using their knowledge of pharmaceutical chemistry, solubility, etc. Using case studies available in the literature, students develop a quantitative analysis experiment for 1,4-butanediol extracted from the toy beads and, through approximation, relate the extractable amount of 1,4-butanediol to dose-response …
The Occurrence Of False Positive Tests For Gunshot Residue Based On Simulations Of The Suspect's Occupation, Christopher R. Dockery, Matthew B. Rosenberg, Kimberly Kammerdiener, Lauren E. Mcadams
The Occurrence Of False Positive Tests For Gunshot Residue Based On Simulations Of The Suspect's Occupation, Christopher R. Dockery, Matthew B. Rosenberg, Kimberly Kammerdiener, Lauren E. Mcadams
Faculty and Research Publications
Samples collected from high-risk occupations, or simulations thereof, are analyzed for elemental composition using laser-induced breakdown spectroscopy (LlBS) to determine the occurrence of false positive gunshot residue results generated in the work environment. Previous work involving the study of lifetime of detectable amounts of gunshot residue on the hands of a suspect shooter found that gunshot residue exists up to 5.27 days after a firearm discharge. However, certain environmental and/or occupational false positive tests for gunshot residue could result when sampling non-shooters. Samples collected from occupations or simulations thereof include welding, pyrotechnics, key cutting, mechanics, and paper products all of …