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Biochemistry Commons

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Full-Text Articles in Biochemistry

Ascorbic Acid, Lipid Peroxidation, And Aging, Brian Evan Leibovitz May 1979

Ascorbic Acid, Lipid Peroxidation, And Aging, Brian Evan Leibovitz

Dissertations and Theses

The role of ascorbic acid with regard to lipid peroxidation and aging has been examined. A thorough literature analysis indicates that free radical-induced lipid peroxidation is a plausible biochemical explanation for aging. Lipid peroxidation causes cellular damage due to altered enzyme activities, error-prone nucleic acid metabolism, and membrane dysfunction, as well as the accumulation of aging pigments in the lysomes. Ascorbic acid, a water soluble free radical quencher, was examined with regard to carbon tetra-chloride-induced lipid peroxidation and in vivo aging. Carbon tetrachloride, a well-known free radical inducer, caused marked increases in the ration of oxidized/reduced vitamin C only …


Steriodogenesis In Mouse Preimplantation Embryos, Marcia E. Kendall Feb 1979

Steriodogenesis In Mouse Preimplantation Embryos, Marcia E. Kendall

Morehead State Theses and Dissertations

A thesis presented to the faculty of the School of Sciences and Mathematics at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Biology by Marcia E. Kendall February 8, 1979.