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Full-Text Articles in Biochemistry
Characterization Of The Clostridioides Difficile Glycosyl Hydrolase Ccsz, Brian Lowrance
Characterization Of The Clostridioides Difficile Glycosyl Hydrolase Ccsz, Brian Lowrance
Theses and Dissertations (Comprehensive)
Bacteria inhabit many of the harshest environments on Earth; persisting and thriving in conditions thought to be unsuitable for life. One common strategy to withstand these environments is the formation of a biofilm. Biofilm composition varies greatly, depending on the underlying community that produces it. Cellulose, a polymer consistently prevalent in biofilms, has been identified as a virulence factor in many pathogens and is suspected to be involved in pathogenesis by Clostridioides difficile. C. difficile is the #1 cause of hospital acquired diarrhea, which can range from mild to life-threatening infections. Biofilm formation is hypothesized to be involved in …