Life Sciences Commons^™

Biochemical Parameters Of Hereditary Chondrodysplasia In Mice, Trent D. Stephens

Theses and Dissertations

Cartilage from newborn mice homozygous for chondrodysplasia contains normal quantities of protein and chondroitin sulfate. Mutant fetal cartilage incorporates normal amounts of sulfate, glucose, and glucosamine. Overnight rinsing with water removes about 25% of the incorporated sulfur and existing uronic acid from mutant ribs and about 55% from mutant limbs. Control ribs and limbs are affected very little by such a rinse. The diffusability of chondroitin sulfate (represented by incorporated sulfur and uronic acid) may be due to a lack of covalent bond formation between chondroitin sulfate and collagen.

Effects Of Unilateral Ablation Of The Optic Nerve In Feral Mus Musculus, Otha Ray Rains Jr.

University of the Pacific Theses and Dissertations

The general organization and 'function of the vertebrate visual system has been under Investigation since the late nineteenth century (Gudden, lS7Qa, Gudden, 1870b). The organization of optic tracts and subcortical optic centers for the majority of vertebrates studied are found to be similar in both structure and function (Gudden, 1870a, Gudden, 1870b, Minkowski, 1913» Minkowski, 1920, and Lashley, 193^a). The sense organ, the eye, contains specific photoreceptor cells designated as either retinal rods or retinal cones. These two types of retinal cells possess an ability to convert light quanta into nerve impulses. The nerve impulses are transmitted via the optic …

A Simulation Model Of Peromyscus Leucopus In An Area Of The Great Dismal Swamp, James E. Paschal Jr.

Biological Sciences Theses & Dissertations

A computer simulation model was developed to explain the population dynamics of the white-footed mouse (Peromyscus leucopus) in an area of the Great Dismal Swamp. The model was designed to provide an experimental base for future studies. The model indicates relationships between food availability, home range size, competition with Peromyscus nuttali habitat selection and reproduction.

White-footed mice were trapped in the Old Dismal Town site during each season from April, 1972 through March, 1973. The age-sex structure of the population was determined, and was compared with the simulated structure. Although there were significant discrepancies between the comparisons, the …

Growth And Development Of The Western Harvest Mouse, Reithrodontomys Megalotis Megalotis, Gary H. Richins

Theses and Dissertations

Growth rates, gestation period, litter size, reproductive age, sex ratios, and development were studied on 198 litters of Reithrodontomys megalotis megalotis. Growth was characterized by several standard skull and body measurements, and was partitioned into four phases of 1-3, 4-12, 13-22, and 23-70 days. Growth was best described by measurements of tail length, ear length, and dried eye lens weight. Reproductive activity began as early as 38 days for females and 59 days for males. Gestation period was 22 days and mean litter size was 3.83 (range 1-7). Sex ratio was 53.49% males to 46.51% females. Reproductive efficiency was 53.53%. …

The Effects Of Ultraviolet Irradiation On The Pigment Cells Of The Pet/Wmr Mouse Epidermis, Vaughan Henry Howard Jr.

Master's Theses

Epidermal melanocytes in mammals are known to occur in a variety of shapes, sizes, and colors. The basic melanocyte morphology is dependent upon genetics, but there are a number of environmental factors that can cause modification.

In the epidermis of PET/\vrnr mice, the population of rnelanocytes reaches a peak and begins to decline during the first post-natal week, and has disappeared within four weeks. Dispersed among the large, highly DOPA-reactive melanocytes are miniature melanocytes. These miniature melanocytes are weakly DOPA-reactive and appear early in the post-natal period. The miniature melanocyte population is relatively constant and these miniature cells are among …

The Induced Differentiation Of Mouse Ectoderm To Epidermis By Growth On Freeze-Thawed Dermis, Albert Joseph Banes

Master's Theses

Previous investigators have grown or maintained adult or embryonic skin in tissue culture and on the chorioallantoic membrane (CAM) of chickens. These studies have revealed two important factors involved in culturing skin: (1) the presence of an inducer which originates in the dermis and affects the phenotype of epithelial cells; and (2) the influence of the physical surface of the substrate on which epidermis is cultured.

The current investigation presents evidence that ectoderm from the limb buds of 10 to 12 day-old mouse embryos can form an epidermis when combined with dermis killed by alternate freezing and thawing, and cultured …

Possible Carriers In Mouse Erythrocytes, Joseph Doyle Mcclure

University of the Pacific Theses and Dissertations

Early qualitative erythrocyte permeability studies (Gryns, 1896; Hedin, 1897) revealed the wide range of non-electrolyte permeability rates across a cell membrane composed of lipid molecules. Theoretically, water-soluble non-electrolytes such as glycerol, ethylene glycol and erythritol would penetrate less rapidly than lipid-soluble non-electrolytes. It was thought that the rate of penetration of water-soluble non-electrolytes was inversely proportional to their molecular size and the penetration of lipid-soluble non-electrolytes was directly proportional to their lipid-solubility.

Refractoriness Of Pet Mouse Integument To The Nerve Growth Factor, Walter Hollified Dorman

Master's Theses

This paper deals with the refractoriness of PET mouse integument to the subcutaneous administration of nerve growth factor. Newborn mice were injected once daily with NGF through ten injections. Gross and histological examination showed that the skin of the experimental animals was completely unresponsive to this agent. No alterations in the hair growth cycle or pattern were observed.

A Comparative Study Of The Sulfhydryl Groups In The Gastrocnemius Of The Normal And X-Irradiated Pet Mouse, Robert Edward Shervette

Master's Theses

It has been recognized that hyperpigmentation of the skin is the result of eliminating the. -SH inhibition when treatment is by x-irraidiation. The results of a. study by fieams and Schaeffer indicate : a progressive increase of melanocytes in the skin with an increasing dosage of x-irradiation. However, it was also noted that the effect of x-irradiatin on the gastrocnemius of the PET mouse resulted in a decrease in the number of intramuscular melanocytes. The present study was designed to determine whether the changes in the x-irradiated muscle is related to possible changes in -SH concentration.The technique employed is a …

The Effects Of A Nerve Growth-Promoting Protein On The Integument Of Pet Mice, Craig Bauman Satterlee

Master's Theses

A factor which specifically stimulates the growth of sensory and sympathetic nerve cells has been under investigation for a number of years. This factor, originally isolated in 1951, from mouse sarcomas 37 and 180, was named the "nerve growth factor". Its action was first shown in vivo by inoculating the sarcoma into chick embryos and subsequently in vitro by culturing chick ganglia and mouse sarcoma together. In the years immediately following the initial discovery, much more potent sources of NGF were found in the salivary glands and salivary secretions of a variety of species. These include rattle snake venom, and …

The Distribution Of Three Taxa Of Peromyscus In Central Washington, Gay Harold Engelsen

All Master's Theses

One aspect of the study was to define the present ranges of all types of Peromyscus in the study area; the other to determine the extent of interfertility of the groups.

The Effects Of Single-Dose X-Irradiation On Melanocytes In The Leg Musculature And Skin Of The Pet Mouse, Barry Eckert Schaeffer

Master's Theses

While most investigations have been limited to the study of pigment cells in the epidermis and hair follicles, this work embraces pigmentation of the leg muscles and dermis as well. To this end, PET mice were used which have an abundance of pigment cells in the leg muscles, but which show restriction of integumentary melanocytes to the dermis and hair. This characteristic provided the unique opportunity of comparing isolated systems of pigment cells in their response to identical stimuli of x-rays. Because pigment cells originate in the neural crest early in development and migrate throughout the embryo, all pigment cells …

Anticoagulants For The Control Of Rats And Mice, C D. Gooding

Journal of the Department of Agriculture, Western Australia, Series 4

LATELY there have been many requests for information on suitable poisons to use in baiting rats and mice.

Most enquirers have stated that they "tried a certain brand of bait" and found that the rats only "ate it up and kept coming back for more."

This article on Warfarin—as a rat and mouse poison—is presented to clear up some of the problems of rodent poisoning.

Distribution Of Mice Populations In The Winona Area, Roger Flattum

Journal of the Minnesota Academy of Science

Six mice habitats in Winona County, Minnesota, were censused by means of snap traps. Examples of marsh, dry meadow, and woods habitat in an upland environment were selected in East Burns Valley south of Winona. Corresponding habitats in a flood plain -environment were located on Prairie Island northwest of the city. These are representative of the non-agricultural habitats of Winona County.

Rats And Mice And Their Control, C D. Gooding, J. L. Long

Journal of the Department of Agriculture, Western Australia, Series 4

BEFORE colonisation by the white man, Australia contained over 50 species of rats and mice.

Although several of these native species have been known to breed to plague proportions they are normally slower breeders than the introduced species.

Once settlement had been established on our shores it was only a matter of time before the introduction of more of these pests, occurred probably from the British Isles.

Some Factors Affecting The Utilization Of Space By Mice Of The Genus Peromyscus, Howard D. Orr

Journal of the Minnesota Academy of Science

No abstract provided.

A Study Of The Utah Pocket Mice Of The Genus Perognathus, Merlin L. Killpack

Theses and Dissertations

The objectives of this study were: (1) to make a detailed study of the distribution of the genus Parognathus in Utah; (2) to determine if any species or races not now recorded occur in the state; (3) to bring together notes on life histories of this genus, both from the literature and field studies; and (4) to determine habitat preferences of the species represented. This paper lists 14 subspecies belonging to 7 species of Perognathus occurring in Utah. One species is a new occurrence record, Perognathus fasciatus callistus, from northeastern Utah east of the Green River. The ranges of Perognathus …

Nile Blue Staining Of The Prostate Gland Of Living Mice, Herbert M. Schiller

Biology Honors Papers

This 36 page thesis examines the effect of Nile blue dye on the prostate of the mouse and an attempt to analyze the nature of the visible prostatic granules.

Life History Studies Of The Mouse, Peromyscus Truei Nevadensis, Lowell S. Miller

Theses and Dissertations

Peromyscus truel's a fairly common inhabitant of the upper sonaranlife zone of the Western States. It is an excellent laboratory anlmal with the limitation that captivity must be accompanied by forced activlty, in order to keep the animals within the limits of normal activity. This mouse is polyestrous and breeds from early spring to late fall. Observations have shown pregnancy in late September and in early February. It is the writer's belief that ovulation in the ovary occurs only when copulation has taken lace, because corpora lutea has only been found in pregnant or lactating females. The evidence is scanty …