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Expanded Concept And Revised Taxonomy Of The Milliped Family Xystodesmidae Cook, 1895 (Polydesmida: Leptodesmidea: Xystodesmoidea): Incorporations Of Euryuridae Pocock, 1909 And Eurymerodesmidae Causey, 1951, Taxon Revivals/Proposals/Transferrals, And A Distributional Update, Rowland M. Shelley, Jamie M. Smith

Insecta Mundi

Euryuridae Pocock 1909 and Eurymerodesmidae Causey 1951, both endemic to the eastern/central United States (US), are incorporated into Xystodesmidae Cook 1895 and reduced to subfamilies and (sub)tribes n. stats. Euryurina and Melaphina Brolemann 1916, n. stats., are sister-taxa that differ primarily in epiproctal configurations and comprise Euryurini; sister-taxa Eurymerodesmina and Nannariina Hoffman 1964, n. stats., the latter transferred from Xystodesminae, comprise Eurymerodesmini, n. stat., in which plesiomorphic forms exhibit sublinear, “stick-like,” and subapically curved/bent gonopodal acropodites with moderately-long to long hairs, often with distal tufts, on their “inner” surfaces. Additional transferrals include Wamokia Chamberlin from the …

Erratum To Cano (2018): A New Anomiopus Westwood (Coleoptera: Scarabaeidae: Scarabaeinae) From The Mayan Biosphere Reserve, Petén, Guatemala, Enio B. Cano

Insecta Mundi

After publication of Cano (2018), it was noticed that the wrong holotype photographs of Anomiopus cirulito Cano were included in Figure 3, resulting in images that did not correspond to the captions. The author and the Insecta Mundi editorial staff apologize for this error. The intended version of Figure 3 is reproduced here. Insecta Mundi has also released a revised version of the Cano (2018) manuscript, with this error corrected. However, the revised version is not an official peer-reviewed article, and anyone wishing to reference the findings of Cano (2018) should cite the original manuscript or this erratum.

A New Species Of Philacelota Heller (Scarabaeidae: Melolonthinae: Melolonthini) From Flores Island, Indonesia, Jiri Zidek

Insecta Mundi

Philacelota jakli sp. n. (Scarabaeidae: Melolonthinae: Melolonthini) is described, illustrated and compared with the other two known congeners, P. submaculata Heller and P. sulana Heller. Philacelota sub maculata is here designated the type species for the genus.

New Species And Records Of Elateridae (Coleoptera) From Cuatrociénegas, Coahuila, Mexico, Paul J. Johnson, David C. Lightfoot

Insecta Mundi

Eleven species of Elateridae (Coleoptera) were collected during a two-year arthropod inventory survey at the Cuatrociénegas Natural Protected Area, Coahuila, Mexico. Aeolus cuatro new species, Horistonotus coahuila new species, and Megapenthes cienegas new species are described for the first time. Additionally reported as new state records are Conoderus athoides (LeConte), C. lividus (De Geer), Deilelater mexicanus (Champion), Esthesopus parcus Horn, and Dipropus rufulus (Candèze). Sixteen species of click beetle are now recorded from Coahuila. The sampled habitats and the environmental setting are briefly described with images of each sampling site.

Once especies de Elateridae (Coleoptera) fueron recolectadas durante …

Description Of Phyllium (Phyllium) Conlei, New Species, And A First Look At The Phylliidae (Phasmatodea) Of The Lesser Sunda Islands, Indonesia, Royce T. Cumming, Pablo Valero Riquelme, Sierra N. Teemsma

Insecta Mundi

The Phylliidae (Phasmatodea) diversity of the Lesser Sunda Islands, Indonesia is preliminarily examined, and revealed to be notably lacking in completeness with only two species currently recorded. Of the nine islands/ island groups within the Lesser Sunda Islands, only the westerly islands (Bali and Lombok) have single species recorded: Phyllium (Pulchriphyllium) pulchrifolium Audinet-Serville, 1838, from Bali, and Phyllium (Phyllium) conlei Cumming, Valero, and Teemsma, new species, from Lombok. The latter species is herein described and differentiated from congenerics. To conclude, with so few species recorded from the Lesser Sunda Islands, a key to species for Java and the Lesser …

Are Miami Blues In Cuba? A Review Of The Genus Cyclargus Nabokov (Lepidoptera: Lycaenidae) With Implications For Conservation Management, Deborah L. Matthews, Jacqueline Y. Miller, Andrew D. Warren, James K. Toomey, Roger W. Portell, Terry A. Lott, Nick V. Grishin

Insecta Mundi

We review the genus Cyclargus Nabokov (Lepidoptera: Lycaenidae) based on detailed comparative analyses of wing patterns, genitalia, and mitochondrial COI DNA barcode sequences, and suggest that Cyclargus is composed of four species: C. thomasi (Clench), C. woodruffi (W. Comstock and Huntington), C. ammon (Lucas), and C. dominica (Möschler). The following new subjective synonyms are proposed: C. erembis Nabokov syn. n. and C. kathleena K. Johnson and Matusik syn. n. are C. thomasi noeli (W. Comstock and Huntington); C. sorpresus K. Johnson and Matusik syn. n. and C. shuturn K. Johnson and Bálint syn. n. are C. ammon; and Cyclargus …

Generic Changes In The Stag Beetle Tribe Aesalini (Coleoptera: Lucanidae: Aesalinae) With The Description Of Two New Species, M. J. Paulsen

Insecta Mundi

The status of genera and species in the stag beetle tribe Aesalini (Coleoptera: Lucanidae: Aesalinae) is revised. The Asian subgenus Zelenkaesalus Krikken, formerly included within Echinoaesalus Zelenka, is elevated to generic level based on the presence of complete ventral sulci and the form of the ocular canthus. This results in the following new combinations: Z. cechovskyi (Huang et al.), Z. gedeensis (Huang and Wu), Z. javanus (Krikken), Z. sabahensis (Zelenka), and Z. timidus (Krikken). Zelenkaesalus pazuzus Paulsen, new species, is described from the Philippines and is the first record of the subfamily for the country. A new genus Strabaesalus …

Four Submarginal Cells On A Forewing Of Melitoma Taurea (Say) (Hymenoptera: Apidae), And A Summary Of Known Records Of Atypical And Variable Numbers Of Submarginal Cells, Eugene J. Scarpulla

Insecta Mundi

A specimen of Melitoma taurea (Say) (Hymenoptera: Apidae) was captured on Hart-Miller Island, Chesapeake Bay, Baltimore County, Maryland. The specimen possessed the typical three submarginal cells on the right forewing but exhibited four submarginal cells on the left forewing due to the presence of an additional submarginal crossvein dividing the second submarginal cell. The presence of four submarginal cells is a rare occurrence in bees. Besides documenting this occurrence, this paper presents a summary of known published and previously unpublished records of atypical and variable numbers of submarginal cells. Published records were found for 66 species: Colletidae (1), Andrenidae (28), …

Revisión Taxonómica De Pseudococcus Westwood (Hemiptera: Pseudococcidae) De Centro Y Sud América Con Descripciones De Especies Nuevas, María C. Granara De Willink, Patricia González

Insecta Mundi

Se tratan 50 especies de Pseudococcus Westwood (Hemiptera: Pseudococcidae) encontradas en Centro y Sud América. Se describen 16 especies nuevas: Pseudococcus acaena Granara de Willink sp. n., P. bahiensis Granara de Willink sp. n., P. calchaquii Granara de Willink sp. n., P. chaquensis Granara de Willink sp. n., P. colombiensis Granara de Willink sp. n., P. cubaensis Granara de Willink sp. n., P. cuyoensis Granara de Willink sp. n., P. debilis Granara de Willink sp. n., P. dumetum Granara de Willink sp. n., P. insuetus Granara de Willink sp. n., P. lanatii Granara de Willink, sp. n., P. neuquenensis Granara …

Environmental Mycobacterium Avium Subsp. Paratuberculosis Hosted By Free-Living Amoebea, Ascel Samba-Louaka, Etienne Robino, Thierry Cochard, Maxime Branger, Vincent Delafont, Willy Aucher, Wilfrid Wambeke, John Bannantine, Franck Biet, Yann Héchard

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Mycobacterium avium subsp. paratuberculosis is responsible for paratuberculosis in animals. This disease, leading to an inflammation of the gastrointestinal tract, has a high impact on animal health and an important economic burden. The environmental life cycle of M. avium subsp. paratuberculosis is poorly understood and several studies suggest that free-living amoebae (FLA) might be a potential environmental host. FLA are protozoa found in water and soil that are described as reservoirs of pathogenic and non-pathogenic bacteria in the environment. Indeed, bacteria able to survive within these amoebae would survive phagocytosis from immune cells. In this study, we assessed the in …

Primer Registro De Omosita Colon (Linnaeus) (Coleoptera: Nitidulidae: Nitidulinae) Recolectada En Cadáveres De Cabrito (Capra Aegagrus Hircus Linnaeus) En Buenavista, Saltillo Coahuila, México, Hermelindo Hernádez-Torres, Oswaldo García-Martínez, Isabel Salazar-García, Luis Alberto Aguirre-Uribe, Sergio Rene Sánchez-Peña

Insecta Mundi

Adultos de Omosita colon (Linnaeus) (Coleoptera: Nitidulidae: Nitidulinae) recolectados sobre cadáveres del cabrito (Capra aegagrus hircus (Linnaeus)) en las etapas de post-descomposición y esqueletonización, representa el primer reporte de esta especie en carroña para Saltillo, Coahuila, México. Para esta región de México se sugiere a O. colon como un indicador potencial en la entomología forense para determinar el periodo en que una persona o animal fallecen. Se presenta una descripción general del género y características taxonómicas de la especie para su identificación.

Adults of Omosita colon (Linnaeus) (Coleoptera: Nitidulidae: Nitidulinae), collected on goat (Capra aegagrus hircus (Linnaeus)) carcasses …

Description Of Two New Bolivian Cerambycidae And A Costa Rican Record For An African Prionine (Coleoptera), James E. Wappes, Antonio Santos-Silva, Maria Helena M. Galileo

Insecta Mundi

Two new species of Cerambycidae (Coleoptera) are described from Bolivia: Compsibidion woodleyi Wappes, Santos-Silva and Galileo (Cerambycinae: Neoibidionina): and Drycothaea dozieri Wappes, Santos-Silva and Galileo (Lamiinae: Calliini). Illustrations of the new species are included. Mallodon downesii Hope, 1843 (Prioninae: Macrotomini) is reported for the first time in Costa Rica.

Waste Not, Want Not: Using Source-Separated Urine To Cultivate Maize In The Southern Highlands, Tanzania, Lucy Hatfield

Dissertations, Master's Theses and Master's Reports

In Sub-Saharan African countries, soil fertility is low due to unsustainable agricultural practices and little to no access to chemical fertilizer. Poor yields have resulted in many of these countries struggling to produce enough food to feed their growing populations. Human urine has been used as an effective, low-cost alternative to chemical fertilizers in greenhouse and plot trials on a variety of vegetables, but its effects on elemental grain composition in cereal crops are largely unknown. Here we tested whether diluted human urine applied as a fertilizer can increase maize crop growth, yield and nutritional content on small family-owned plots. …

Modeling Canopy Effect In The Great Lakes Cladophora Model, Ankita Bakshi

Dissertations, Master's Theses and Master's Reports

Cladophora glomerata is a filamentous green alga native to the Great Lakes. However, its nuisance growth in phosphorus rich waters negatively affects the lakes’ aesthetic and water quality. The Great Lakes Cladophora Model (GLCM) v1, developed in 1982, was the first mechanistic model to simulate Cladophora growth basing phosphorus availability and environmental conditions followed by Cladophora Growth Model and GLCM v2. In this study, the light and temperature mediation factors for Cladophora net growth are revised as a necessary step prior to the development of a self-shading algorithm. The concept of a fixed-value, maximum achievable biomass (carrying capacity) employed in …

Agroforestry Standards For Regenerative Agriculture [Review], Craig R. Elevitch, D. Niki Mazaroli, Diane Ragone

United States Department of Agriculture, Forest Service / University of Nebraska-Lincoln: Faculty Publications

Agroforestry is increasingly being recognized as a holistic food production system that can have numerous significant environmental, economic, and social benefits. This growing recognition is paralleled in the USA by the budding interest in regenerative agriculture and motivation to certify regenerative practices. Current efforts to develop a regenerative agriculture certification offer an opportunity to consider agroforestry’s role in furthering regenerative goals. To understand this opportunity, we first examine how agroforestry practices can advance regenerative agriculture’s five core environmental concerns: soil fertility and health, water quality, biodiversity, ecosystem health, and carbon sequestration. Next, we review a subset of certification programs, standards, …

Distance Models As A Tool For Modelling Detection Probability And Density Of Native Bumblebees, Darin J. Mcneil, Clint R. V. Otto, Erin L. Moser, Katherine R. Urban‐Mead, David E. King, Amanda D. Rodewald, Jeffery L. Larkin

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Effective monitoring of native bee populations requires accurate estimates of population size and relative abundance among habitats. Current bee survey methods, such as netting or pan trapping, may be adequate for a variety of study objectives but are limited by a failure to account for imperfect detection. Biases due to imperfect detection could result in inaccurate abundance estimates or erroneous insights about the response of bees to different environments. To gauge the potential biases of currently employed survey methods, we compared abundance estimates of bumblebees (Bombus spp.) derived from hierarchical distance sampling models (HDS) to bumblebee counts collected from fixed‐area …

Kit 16: Children's Library Kit, Lauren Segreto

Department of Entomology: Distance Master of Science Projects

Kit 16A- Insect Adaptation This kit serves as an introduction to a variety of insect adaptations. Learn about how insects adjust to their environment with this selection of images and sounds of various insects. Insects communicate with sound, with visuals, they walk, run, fly, and sometimes even swim, some insects are capable of camouflage, and others are pollinators. This kit provides a book focusing on the chirping of crickets, the reasons they chirp, as well as how they do it as well as a variety of pictures of other insects and their different adaptations that allow then to survive in …

Mosquito Abatement Monitoring: West Nile In Los Angeles County, Elisa Gonzalez

Department of Entomology: Distance Master of Science Projects

West Nile virus (WNV) has become established across the U.S. with heightened activity causing significant human illness. Monitoring methods to predict the risk of human infection are urgently need to initiate timely preventative measures and justify the expense of implementing costly or unpopular control measures, such as aerial spraying or curfews. This research outlines several ways to further improve the productive power of monitoring mosquitoes. These results demonstrate that mosquito monitoring provides a valuable public health tool for assessing the risk of human arboviral infections, allocating limited public health resources, and justifying emergency control actions.

A key challenge has been …

Mimicry In Insects: An Illustrated Study In Mimicry And Cryptic Coloration In Insects, Merrie Schultz

Department of Entomology: Distance Master of Science Projects

INSECT MIMICRY 4

WHAT IS MIMICRY? 5

MÜLLERIAN MIMICRY 7

MÜLLERIAN MIMICRY 8

YELLOWJACKET – VESPULA SPP. 9

HONEY BEE – APIS SPP. 10

BUMBLE BEE – BOMBUS SPP. 11

VELVET ANT (COW KILLER) – DASYMUTILLA OCCIDENTALIS 12

BLISTER BEETLE – EUPOMPHA ELEGANS 13

THREAD-WAISTED WASP – AMMOPHILA SPP. 14

MONARCH BUTTERFLY – DANAUS PLEXIPPUS 15

VICEROY BUTTERFLY – LIMENTIS SPP. 16

BATESIAN MIMICRY 17

BATESIAN MIMICRY 18

METALLIC WOODBORING BEETLE – ACMAEODERA SPP. 19

WASP BEETLE – CLYTUS SPP. 20

FLOWER LONGHORN BEETLE – TYPOCERUS SPP. 21

BEE BEETLE – TRICHIUS SPP. 22

BEE FLY – BOMBYLIUS SPP. 23 …

Integrated Pest Management Plan, Bryon Kacprzyk

Department of Entomology: Distance Master of Science Projects

This Integrated Pest Management Plan is to provide a framework through which pest management is defined and accomplished in northern Lowndes County in Georgia and focusing on Moody AFB. The plan identifies elements of the program to include health, environmental protection, safety, training, pest identification and pest management. This plan is to be used as a tool to reduce pesticide use, enhance environmental protection, and maximize the use of integrated pest management techniques. The overall objective of the program is to provide guidance for operating an effective pest management program. Integrated Pest Management (IPM) principles are stressed and application of …

Understanding And Controlling The Red Legged Ham Beetle (Necropia Rufipes), Alexandria Hammel

Department of Entomology: Distance Master of Science Projects

The Red Legged Ham Beetle (Necrobia rufipes), RLHB has fascinated me since the moment we met. The beautiful greens and blues that sparkle from its elytra, the sharp and fast red legs that flash just below the body and just last month I was able to see a RLHB in flight for the first time. My squeal of delight was not left un-mocked by my coworkers. This beetle is a detrimental and determined stored product pest. One that, we in the pet food business, don’t take lightly. This generated a need for control in warehousing as distribution but …

Let’S Go Find A Bug, Jonathan Mcghee

Department of Entomology: Distance Master of Science Projects

The insect world is largely a mystery to many people. In fact, large parts of the insect world are mysteries to even those that study them. With the help of an extraordinary camera man, a vision, and the spirit of adventure, we set off on an endeavor to bring the minute insect world to the everyday person. Please join us as we capture a small amount of the biodiversity of Southern California and bring it right to your front door. Let’s go find a bug.

Managing The Economy Of Public Mosquito Control Thresholds, Peter T. Taylor

Department of Entomology: Distance Master of Science Projects

Seventy-four mosquito surveillance data sets involving over 35 species, from January 2013 to December of 2014 have been obtained with permission from Dr. Carl Boohene and Polk County Mosquito Control District in Central Florida and used as data for this project. These data are utilized to propose a practical, economically-based decision rule model that uniquely integrates human populations with mosquito species populations and budgetary constraints. Two different decision rule conventions are proposed and the choice to go with one of them reflects differing economic expenditure inroads on budgeted chemical and equipment resources. In general, if the threshold is higher, then …

Tellurite Resistance In Shiga Toxin-Producing Escherichia Coli , Gentry L. Lewis, Quentin R. Jorgensen, John Dustin Loy, Rodney A. Moxley

School of Veterinary and Biomedical Sciences: Faculty Publications

Potassium tellurite ( K₂TeO₃) is an effective selective agent for O157:H7 Shiga toxin-producing Escherichia coli (STEC), whereas tellurite resistance in non-O157 STEC is variable with information on O45 minimal. High-level K₂TeO₃ resistance in STEC is attributable to the ter gene cluster with terD an indicator of the cluster’s presence. Polymerase chain reactions for terD and K₂TeO₃ minimum inhibitory concentration (MIC) determinations in broth cultures were conducted on 70 STEC and 40 non-STEC control organisms. Sixty-six STEC strains (94.3%) were terD+ compared to 28 control organisms (70.0%; P < 0.001). The prevalence of terD in …

Epitope Mapping Of Serca2a Identifies An Antigenic Determinant That Induces Mainly Atrial Myocarditis In A/J Mice, Bharathi Krishnan, Chandirasegara Massilamany, Rakesh H. Basavalingappa, Arunakumar Gangaplara, Rajkumar Rajasekaran, Muhammad Z. Afzal, Vahid Khalilzad-Sharghi, You Zhou, Jean-Jack Riethoven, Shyam S. Nandi, Paras K. Mishra, Raymond A. Sobel, Jennifer L. Strande, David Steffen, Jay Reddy

School of Veterinary and Biomedical Sciences: Faculty Publications

Sarcoplasmic/endoplasmic reticulum Ca²⁺ adenosine triphosphatase (SERCA)2a, a critical regulator of calcium homeostasis, is known to be decreased in heart failure. Patients with myocarditis or dilated cardiomyopathy develop autoantibodies to SERCA2a suggesting that they may have pathogenetic significance. In this report, we describe epitope mapping analysis of SERCA2a in A/J mice that leads us to make five observations: 1) SERCA2a contains multiple T cell epitopes that induce varying degrees of myocarditis. One epitope, SERCA2a 971–990, induces widespread atrial inflammation without affecting noncardiac tissues; the cardiac abnormalities could be noninvasively captured by echocardiography, electrocardiography, and magnetic resonance microscopy imaging. 2) SERCA2a …

Alkaline Stabilization Of Manure Slurry Inactivates Porcine Epidemic Diarrhea Virus, Erin E. Stevens, Daniel N. Miller, Bethany A. Brittenham, Sarah J. Vitosh-Sillman, Bruce W. Brodersen, Virginia L. Jin, John D. Loy, Amy M. Schmidt

School of Veterinary and Biomedical Sciences: Faculty Publications

Hydrated lime manure treatment was evaluated to determine porcine epidemic diarrhea virus (PEDV) susceptibility to alkaline stabilization. At pH 10, PEDV decreased (quantitative polymerase chain reaction) and lost infectivity (swine bioassay). Although ammonium decreased above pH 9 (up to 25%), alkaline stabilization managed to control potential infection from manure sources.

Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry Identification Of Moraxella Bovoculi And Moraxella Bovis Isolates From Cattle, Kara Robbins, Aaron M. Dickey, Michael L. Clawson, John Dustin Loy

School of Veterinary and Biomedical Sciences: Faculty Publications

Infectious bovine keratoconjunctivitis (IBK) is an economically significant disease caused by Moraxella bovis. Moraxella bovoculi, although not reported to cause IBK, has been isolated from the eyes of cattle diagnosed with IBK. Identification of M. bovis and M. bovoculi can be performed using biochemical or DNA-based approaches, both of which may be time consuming and inconsistent between laboratories. We conducted a comparative evaluation of M. bovoculi and M. bovis identification using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) with a database provided by Bruker Daltonics (termed the BDAL database), the BDAL database supplemented with spectra generated in …

Development Of A Multiplex Real-Time Pcr Assay Using Two Thermocycling Platforms For Detection Of Major Bacterial Pathogens Associated With Bovine Respiratory Disease Complex From Clinical Samples, John Dustin Loy, Laura Leger, Aspen M. Workman, Michael L. Clawson, Ece Bulut, Bing Wang

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine respiratory disease complex (BRDC) is one of the most significant diseases of cattle. Bacterial pathogens involved in BRDC include Mannheimia haemolytica, Mycoplasma bovis, Histophilus somni, and Pasteurella multocida. We developed and evaluated a multiplexed real-time hydrolysis probe (rtPCR) assay using block-based Peltier and rotary-based thermocycling on lung tissue, nasal swabs, and deep nasopharyngeal swabs. The rtPCR results were compared to culture or a gel-based M. bovis PCR using statistical analysis to determine optimum quantification cycle (Cq) cutoffs to maximize agreement. The limits of detection were 1.2–12 CFU/reaction for each pathogen. M. haemolytica was the most prevalent organism detected …

Coordinated Regulation Of Transcription By Ccpa And The Staphylococcus Aureus Twocomponent System Hptrs, Joseph M. Reed, Sean Olson, Danielle F. Brees, Caitlin E. Griffin, Ryan A. Grove, Paul J. Davis, Stephen D. Kachman, Jiri Adamec, Greg A. Somerville

School of Veterinary and Biomedical Sciences: Faculty Publications

The success of Staphylococcus aureus as a pathogen is due in part to its ability to adapt to changing environmental conditions using signal transduction pathways, such as metaboliteresponsive regulators and two-component systems. S. aureus has a two-component system encoded by the gene pair sav0224 (hptS) and sav0223 (hptR) that regulate the hexose phosphate transport (uhpT) system in response to extracellular glucose-6-phosphate. Glycolytic intermediates such as glucose-6-phosphate are important carbon sources that also modulate the activity of the global metabolite-responsive transcriptional regulator CcpA. Because uhpT has a putative CcpA binding site in its promoter and …

Novel Docosahexaenoic Acid Ester Of Phloridzin Inhibits Proliferation And Triggers Apoptosis In An In Vitro Model Of Skin Cancer, Theodora Mantso, Dimitrios T. Trafalis, Sotiris Botaitis, Rodrigo Franco, Aglaia Pappa, H. P. Vasantha Rupasinghe, Mihalis I. Panayiotidis

School of Veterinary and Biomedical Sciences: Faculty Publications

Skin cancer is among the most common cancer types accompanied by rapidly increasing incidence rates, thus making the development of more efficient therapeutic approaches a necessity. Recent studies have revealed the potential role of decosahexaenoic acid ester of phloridzin (PZDHA) in suppressing proliferation of liver, breast, and blood cancer cell lines. In the present study, we investigated the cytotoxic potential of PZDHA in an in vitro model of skin cancer consisting of melanoma (A375), epidermoid carcinoma (A431), and non-tumorigenic (HaCaT) cell lines. Decosahexaenoic acid ester of phloridzin led to increased cytotoxicity in all cell lines as revealed by cell viability …