Life Sciences Commons^™

Regulation Of Hgf Expression By Δegfr-Mediated C-Met Activation In Glioblastoma Cells, Jeannine Garnett

Dissertations and Theses (Open Access)

Overexpression of the hepatocyte growth factor receptor (c-Met) and its ligand, the hepatocyte growth factor (HGF), and a constitutively active mutant of the epidermal growth factor receptor (∆EGFR/EGFRvIII), occur frequently in glioblastoma. c-Met is activated in a ligand-dependent manner by HGF or in a ligand-independent manner by ∆EGFR. Dysregulated c-Met signaling contributes to the aggressive phenotype of glioblastoma, yet the mechanisms underlying the production of HGF in glioblastoma are poorly understood. We found a positive correlation between HGF and c-Met expression in glioblastoma, suggesting that they are coregulated. This is supported by the finding that in a c-Met/HGF axis-dependent glioblastoma …

The Role Of Receptor Tyrosine Kinase Axl In Pancreatic Ductal Adenocarcinoma And Its Regulation By Hematopoietic Progenitor Kinase 1, Xianzhou Song

Dissertations and Theses (Open Access)

Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive malignancies with less than 5% of five year survival rate. New molecular markers and new therapeutic targets are urgently needed for patients with PDA. Oncogenic receptor tyrosine kinase Axl has been reported to be overexpressed in many types of human malignancies, including diffuse glioma, melanoma, osteosarcoma, and carcinomas of lung, colon, prostate, breast, ovary, esophagus, stomach, and kidney. However, the expression and functions of Axl in PDA are unclear. We hypothesized that Axl contributes to the development and progression of PDA. We examined Axl expression in 54 human PDA samples …

In Search Of Shell Space: A Look At A Unique Sea Turtle Nesting Behavior, Mia Dawson

The Synapse: Intercollegiate science magazine

No abstract provided.

Issue 0

The Synapse: Intercollegiate science magazine

No abstract provided.

To The Brink Of Understanding, Isaac H. Mcceery

The Synapse: Intercollegiate science magazine

No abstract provided.

So That They May Model, Isaac H. Mcceery

The Synapse: Intercollegiate science magazine

No abstract provided.

Artificial Intelligence In Digital Music: Musicians Using Techology To Streamline The Creative Process, Sam Fisher

The Synapse: Intercollegiate science magazine

No abstract provided.

Kinship Between The Kingdoms: Horizontal Gene Transfer, Darrin Schultz, Ben Garfinkel

The Synapse: Intercollegiate science magazine

No abstract provided.

Its About (Geological) Time, Paris Achenbach

The Synapse: Intercollegiate science magazine

No abstract provided.

Cruzin' With Yolanda: The Life And Research Of The Biology 100 Icon

The Synapse: Intercollegiate science magazine

No abstract provided.

The Short-Term Effects Of Cortisol

The Synapse: Intercollegiate science magazine

No abstract provided.

Enhancing Soybean Profitability Using Portfolio Theory, Osemenkhian Cynthia Onyechere

Graduate Theses and Dissertations

The purpose of this study was to estimate the effect of utilizing portfolio theory on producers' profitability in the production of soybeans in three test locations - Keiser, Marianna and Rohwer - in Arkansas. The study used empirical yield data, their variances and covariances over a nine year period (2002-2010) in selecting a portfolio of soybean varieties that maintains or increases yield while minimizing the yield risk. Furthermore, carbon emissions associated with soybean production was estimated by modeling the effect of a potential carbon tax as well as the potential benefit of carbon offset payments resulting from carbon sequestration. The …

But Does It Work? The Impact Of Social Media Use On Interpretive Outcomes And Place Attachments At San Francisco Bay Area Parks, Eric Knackmuhs

Electronic Theses and Dissertations

Many parks are now using social media sites to connect with visitors but little is known about how effective these efforts have been. This study examined the influence of social media use on interpretive outcomes and place attachment. Visitors to four parks in the San Francisco Bay Area were surveyed twice, once as they exited the park (n = 529) and a second time via email (n = 216) six to ten weeks after visiting. In both surveys, respondents were asked how they use social media to experience parks and to what extent they experienced interpretive outcomes (intellectual and emotional …

Synopsis Of Methods Used To Map Historical Vegetation In Oregon And Washington, Based On General Land Office Survey Notes, John Christy, Edward Alverson

Institute for Natural Resources Publications

Mapping historical vegetation in Oregon and Washington has been ongoing since about 1993. It is based primarily on General Land Office (GLO) surveyors' descriptions of vegetation, recorded between 1851 and about 1940. For areas along the coast and the lower Columbia River, topographic maps ("T-sheets") of the U.S. Coast Survey (later called U.S. Coast and Geodetic Survey, and more recently the National Geodetic Survey)—based on field work conducted between 1852 and 1889—have been integrated whenever possible with GLO data because of their superior cartography and land cover symbology. For more detailed descriptions of mapping methods, see Christy and Alverson (2011) …

Brody-Bertalanffy Growth Curves From Tag And Recapture Studies On Cabezon (Scorpaenichthys Marmoratus) And Gopher Rockfish (Sebastes Carnatus) Of The Central Coast, Christie Yorke

Biological Sciences

No abstract provided.

Agricultural Productivity Growth In Central America And The Caribbean, Ayako Ebata

Department of Agricultural Economics: Dissertations, Theses, and Student Research

This thesis estimates total factor productivity (TFP) growth in the agricultural sector of fourteen regions in Central America and the Caribbean. First, TFP is measured parametrically and non-parametrically, using the Ordinary Least Square (OLS) method and the Maximum Likelihood (ML) method to estimate a translog production function and the Malmquist index approach. Secondly, the thesis incorporates an environmental bad, CO₂ emissions from expansion of agricultural land by sacrificing forest area and estimates environmentally adjusted productivity (EAP) growth rates using an output distance function in order to assess how the growth of TFP rates changes when such a bad is …

Movement Ecology Of An Intercontinental Migratory Bird During Spring Stopover, Emily Beth Cohen

Dissertations

Movement ecology is a component of nearly all aspects of animal behavior and an animal’s decision to move is likely influenced by a complex combination of exogenous and endogenous factors. Therefore, an examination of the causes and consequences of organismal movement provides a conceptual framework for understanding complex behavioral strategies. My dissertation research is focused on the movement ecology of an intercontinental migratory songbird during spring migration. I adopted experimental approaches to study the factors influencing how a songbird migrant, red-eyed vireos (Vireo olivaceus), makes decisions in unfamiliar landscapes from the initiation of spring stopover.

I simulated the …

Homoploid Hybrid Speciation In A Rare Endemic Castilleja From Idaho (Castilleja Christii, Orobanchaceae), Danielle Leigh Clay

Boise State University Theses and Dissertations

Evidence to support the origins of a putative hybrid species with certainty must be determined using several lines of evidence: the presence of genetic additivity of parental marker alleles in a putative hybrid species, along with ecological or niche separation. Novel or transgressive morphological traits obtained through chromosomal rearrangements during hybridization may facilitate niche separation of the hybrid species from progenitor habitats. These evolutionary processes together enforce reproductive isolation and promote an independent evolutionary trajectory in hybrid species. By studying these evolutionary processes in putative hybrid species, researchers may identify hybrid species with confidence.

We employed multiple lines of evidence …

Arkansas Soybean Performance Tests 2011, R. D. Bond, D. G. Dombek, J. A. Still, R. M. Pryor

Arkansas Agricultural Experiment Station Research Series

Soybean variety and strain performance tests are conducted each year in Arkansas by the University of Arkansas System Division of Agriculture Arkansas Crop Variety Improvement Program. The tests provide information to companies developing varieties and/or marketing seed within the state, and aid the Arkansas Cooperative Extension Service in formulating variety recommendations for soybean producers.

The Study Of The Parasitic Fauna In Sciaenops Ocellatus, Lower Laguna Madre, Texas, Veronica Abrigo

Theses and Dissertations - UTB/UTPA

Parasitological investigations provide information on ecosystem health because parasite prevalence and abundance are influenced by biotic and abiotic environmental changes. This survey classified the parasitic fauna of red drum, Sciaenops ocellatus, in the Lower Laguna Madre, TX. Fish (n = 239) were collected from four study sites (May 2005 - June 2006). Parasite identification consisted of digenean and monogenean trematodes, cestodes, larval nematodes, copepods, and protozoans. Parasite prevalence and host length was positively correlated from South Bay (r=0.473), Port Isabel (r=0.533), Arroyo(r=0.314), and Port Mansfield (r=0.630). Significant differences (p<0.001) between zone and parasite prevalence from Arroyo site indicated a higher prevalence of protozoa and monogeneans and reduced prevalence of digeneans. Statistical analyses indicated the greatest difference between Port Isabel and Arroyo sites ( divided by 2= 48.195; p<0.001; df= 14), and the least difference between South Bay and Arroyo sites ( divided by 2= 20.847; p= 1.06; df= 14).

Characterization And Antibiotic Resistance Profile Of Staphylococci In The Lower Rio Grande Valley, Diana E. Trevino

Theses and Dissertations - UTB/UTPA

Staphylococci from part of the natural flora of humans and some, like Staphylococcus aureus, appear to be evolving antibiotic resistance. The Lower Rio Grande Valley (LRGV) is an area of interest due to its proximity to the US/Mexico border where antibiotics could recently be purchased without prescription. Two libraries from community association (CA-S) and environmental association (E-S) have been collected and the staphylococci isolated. We hypothesize that their SCCmec type, which aids the staphylococci in antibiotic resistance, will not display classically defined association schemes and will surface in many species of staphylococci. This study generates antibiotic resistance profiles via antibiotic …

Effect Of Pesticides On Salicylic Acid Binding Protein 2 (Sabp2) And Plant Defense, Joannes Petrus Yuh

Electronic Theses and Dissertations

Tobacco SABP2 has been shown to display high affinity for salicylic acid (SA) and methylsalicylate (MeSA) and plays an important role in SAR signal development. Using biochemical approach, SABP2 has been shown to demonstrate strong esterase activity in converting MeSA to SA. Recent study shows that tetra fluoroacetophenone, a synthetic analog of SA, competitively inhibits SABP2 esterase activity as well as suppresses SAR signal development in tobacco mosaic virus (TMV)-infected tobacco plants. Not much has been studied on the effect of pesticides on plant defenses. Because both AChE and SABP2 are esterase-like proteins belonging to α/β hydroxylase superfamily, we hypothesize …

Feeding Practices Of Mothers In The Gobi Desert Of Mongolia, Julie F. Tate

Electronic Theses and Dissertations

The diets of Mongolia infants are deficient in vitamins and minerals and complementary foods are introduced too early. Breastfeeding is the best source of nutrition for infants until 6 months of age. A survey of 50 Mongolian mothers with children under the age of 5 in the town of Sainshand, Dornogobi, was conducted in July 2011. Mongolian infants are among the highest percent of infants in the world who are exclusively breastfed for the first 6 months of their lives, thus providing them with excellent nutrition. However, complementary feedings and supplements are not appropriately used or understood. Therefore, the diets …

Response To Management Strategies In Young-Growth Giant Sequoia Stands At Mountain Home Demonstration State Forest – Remeasurement Twenty Years After Treatment, Joshua Soderlund

Master's Theses

There is limited information on how young-growth giant sequoia (Sequoiadendron giganteum [Lindl.] Buchholz)/mixed conifer stands respond to forest management strategies. An applied research study was initiated in 1989 when 35 approximately 0.1 acre (0.04 hectare) plots were installed in six young-growth giant sequoia/mixed conifer stands. The objective of this study was to determine if there was a difference after 20 years between treatments (a) thin only, (b) thin and prescribe burn, and (c) control in terms of the effect on overstory growth and yield, understory plants, tree regeneration and downed woody debris. Analysis of variance (ANOVA) for cubic-foot growth …

The Influence Of Chilling And Heat Accumulation On Bloom Timing, Bloom Length And Crop Yield In Almonds (Prunus Dulcis (Mill.)), Melanie M. Covert

Master's Theses

Almonds are one of the first commercial nut trees to bloom in early spring and thus are susceptible to temperature patterns prior to and during bloom which affect bloom timing, bloom length, pollination and nut set. Data used in this project include yearly dates of 90% bloom from 1996-2006, bloom length in days and final crop yields in pounds per tree for Nonpareil and Mission varieties. Data were collected from the University of California Cooperative Extension reports on the 1993-2006 Regional Almond Variety Trials in Butte, San Joaquin and Kern Counties. Temperature pattern models in the form of Chill Hours …

The Effect Of Six Weeks Of Oral Echinacea Supplementation On Erythropoiesis, Nitric Oxide Production, And Exercise Performance, Tyler David Martin

Dissertations

The purpose of the present study was to investigate the effect of six weeks of oral Echinacea supplementation on serum erythropoietin (EPO) and erythropoietic status, plasma nitric oxide [NO], submaximal endurance exercise performance, and maximal oxygen uptake (V˙O_2max). Twenty-four males (mean ± SE): age = 25.2 ± 1.4 yr, height = 178.1 ± 1.4 cm, mass = 78.1 ± 1.6 kg, percent body fat = 12.7 ± 0.9 %, V˙O_max = 52.9 ± 0.9 mL·kg^-1·min^-1 were randomly grouped using a matched-pair, double-blind design and self-administered 8,000 mg·d^-1(5 × 400 mg × 4 …

Ethnic Disparity In 21-Hydroxylase Gene Mutations Identified In Pakistani Congenital Adrenal Hyperplasia Patient, Aysha Habib Khan, Muniba Aban, Jamal Raza, Naeem Ul Haq, Abdul Jabbar, Tariq Moatter

Department of Pathology and Laboratory Medicine

Background: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders caused by defects in the steroid 21 hydroxylase gene (CYP21A2). We studied the spectrum of mutations in CYP21A2 gene in a multi-ethnic population in Pakistan to explore the genetics of CAH.

Methods: A cross sectional study was conducted for the identification of mutations CYP21A2 and their phenotypic associations in CAH using ARMS-PCR assay.

Results: Overall, 29 patients were analyzed for nine different mutations. The group consisted of two major forms of CAH including 17 salt wasters and 12 simple virilizers. There were 14 phenotypic males and 15 females …

Essential Oils Of Cupressus Funebris, Juniperus Communis, And J. Chinensis (Cupressaceae) As Repellents Against Ticks (Acari: Ixodidae) And Mosquitoes (Diptera: Culicidae) And As Toxicants Against Mosquitoes, John F. Carroll, Nurhayat Tabanca, Matthew H. Kramer, Natasha M. Elejalde, David E. Wedge, Ulrich R. Bernier, Monique Coy, James Becnel, Betul Demirci, Kemal Husnu Can Başer, Jian Zhang, Sui Zhang

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Juniperus communis leaf oil, J. chinensis wood oil, and Cupressus funebris wood oil (Cupressaceae) from China were analyzed by gas chromatography and gas chromatography-mass spectrometry. We identified 104 compounds, representing 66.8-95.5% of the oils. The major components were: α-pinene (27.0%), α-terpinene (14.0%), and linalool (10.9%) for J. communis; cuparene (11.3%) and δ-cadinene (7.8%) for J. chinensis; and α-cedrene (16.9%), cedrol (7.6%), and β-cedrene (5.7%) for C. funebris. The essential oils of C. funebris, J. chinensis, and J. communis were evaluated for repellency against adult yellow fever mosquitoes, Aedes aegypti (L.), host-seeking nymphs of the lone …

Endurance Markers Are Related With Local Neuromuscular Response For The Intact But Not For The Acl Reconstructed Leg During High Intensity Running, Kostas Patras, Giorgos Ziogas, Stavros Ristanis, Elias Tsepis, Vasilis Tsiaras, Nikolaos Stergiou, Anastasios D. Georgoulis

Journal Articles

AIM: It has been demonstrated that the local neuromuscular response during high intensity exercise has a strong relationship with endurance markers. However, a diminished neuromuscular response has been reported for the operated leg in athletes having undergone anterior cruciate ligament reconstruction (ACLR). The purpose of the present study was to examine the relationships between endurance markers and the EMG response during high intensity running in ACLR athletes. METHODS: Fourteen ACLR soccer players underwent a GXT test to volitional exhaustion and a 10-min bout of high intensity running. During the 10-min bout, EMG data were recorded at the 3rd …

Identification Of Factors Involved In Dna Methylation Of Cpg-Island-Promoters, Yan Zhang

Dissertations and Theses (Open Access)

Repression of many tumor suppressor genes (TSGs) in cancer is mediated by aberrantly increased DNA methylation levels at promoter CpG islands (CGI). About one-fourth of empirically defined human promoters are surrounded by or contain clustered repetitive elements. It was previously observed that a sharp transition of methylation occurs between highly methylated repetitive elements (SINE or LINE) and unmethylated CGI-promoters (e.g. P16, VHL, CDH and RIL) in normal tissues. The functions that lead to increased CGI methylation in cancer remain poorly understood. We propose that CGI-promoters contain cis-elements for triggering de novo DNA methylation. In the first part of our project, …