Life Sciences Commons^™

Endogenous N-3 Fatty Acids Protect Ovariectomy Induced Bone Loss By Attenuating Osteoclastogenesis, Md Mizanur Rahman, Arunabh Bhattacharya, Jameela Banu, Jing X. Kang, Gabriel Fernandes

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Beneficial effects of n-3 fatty acids (FA) on bone mineral density (BMD) have been reported in mice, rats and human beings, but the precise mechanisms involved have not been described. This study used the Fat-1 mouse, a transgenic model that synthesizes n-3 FA from n-6 FA to directly determine if outcome of bone health were correlated with n-3 FA. Ovariectomized (Ovx) and sham operated wild-type (WT) and Fat-1 mice were fed an AIN-93M diet containing 10% corn oil for 24 weeks. BMD was analysed by dual energy x-ray absorptiometry. Fat-1 Ovx mice exhibited significantly lower level of osteotropic factors like …

Five New Species Of Peltonotus Burmeister (Scarabaeidae: Dynastinae: Cyclocephalini) From Southeast Asia, Mary Liz Jameson, Kaoru Wada

Insecta Mundi

The Southeast Asian scarab beetle genus Peltonotus Burmeister (Scarabaeidae: Dynastinae) is associated with aroid flowers and possesses a unique, articulated maxillary tooth. We describe five new species of Peltonotus: P. animus and P. cybele from Sumatra, P. favonius from Vietnam, P. mushiyaus from Borneo, and P. tigerus from Thailand. The circumscription of P. karubei Muramoto is broadened to include new color variation, and the body size range for the genus is increased with Peltonotus mushiyaus, n. sp., now being the smallest member of the genus. We provide an amended key to species, distribution maps, diagnoses and accompanying comparative …

A Revision Of The Genus Maracandula Currie (Neuroptera: Myrmeleontidae), Robert B. Miller, Lionel A. Stange

Insecta Mundi

Three new species of Maracandula are described from Mexico and included in a key to the five species in Mexico. Diagnoses of the species are given as well as distributional data.

Se describen tres especies nuevas de Maracandula de Mexico y se incluye una clave de las cinco especies conocidas de Mexico.

Xyloryctes Hope, 1837 (Coleoptera: Scarabaeidae: Dynastinae: Oryctini) In The United States. Qui Es Et Ubi Fuisti Et Quo Vadis?, Brett C. Ratcliffe

Insecta Mundi

Two species of Xyloryctes occur in the United States: X. jamaicensis (Drury) and X. thestalus Bates. Identification and distribution of these species has long been confused but is reviewed and clarified here. Xyloryctes jamaicensis occurs only in the eastern half of the U.S. and not in the southwestern U.S. as previously thought, while X. thestalus occurs in Guatemala and southern Mexico northwards to the southwestern United States. This hypothesis is corroborated by biogeographical and host plant data. Three new synonyms are listed for X. thestalus: X. faunus Casey 1915, X. hebes Casey 1915, and X. thestalus borealis Endrödi. The …

Contributions To The Faunistics Of Odonata In Thailand, Michael L. Ferro, Robert W. Sites, Akekawat Vitheepradit

Insecta Mundi

Distribution and habitat information are provided for 1578 adult specimens of Odonata representing 127 species in 70 genera and 16 families that were collected from 143 locations throughout Thailand. Of the species collected, 25 (20%) were represented by a single specimen, and 40 (31%) were collected from a single location. Collections were made at 49 lentic and 85 lotic sites, and an average of 6.9 and 6.6 species were collected at each site in each habitat, respectively.

Kepatuhan Membaca Label Informasi Zat Gizi Di Kalangan Mahasiswa, Siti Zahara, Triyanti Triyanti

Kesmas

Berdasarkan hasil kajian Badan Perlindungan Konsumen Nasional (BPKN), di Indonesia label pangan masih kurang mendapat perhatian dari konsumen. Hanya sekitar 6,7% konsumen yang memperhatikan kelengkapan label produk pangan yang mereka beli. Penelitian ini bertujuan untuk mengetahui tingkat kepatuhan mahasiswa Fakultas Kesehatan Masyarakat Universitas Indonesia membaca label informasi zat gizi dan komposisi makanan kemasan serta faktor-faktor yang mempengaruhinya. Penelitian dengan desain potong lintang (cross-sectional) ini dilakukan terhadap 215 responden. Dari hasil penelitian didapatkan bahwa variabel yang berhubungan bermakna dengan kepatuhan mambaca label informasi zat gizi adalah status pekerjaan ayah (OR = 2,44), sikap kesehatan dan label produk pangan (OR = 2,824), …

First Record Of Curius Chemsaki Nearns And Ray, 2006 (Coleoptera: Cerambycidae: Cerambycinae: Curiini) In Colombia, Eugenio H. Nearns, Ian P. Swift, Luis J. Joly

Insecta Mundi

Curius chemsaki Nearns and Ray, 2006 (Coleoptera: Cerambycidae: Cerambycinae: Curiini), is reported from Colombia for the first time. In addition, the range of this taxon within Venezuela is extended to the Andean Province of Táchira.

The Milliped Family Tingupidae (Chordeumatida) On Kodiak Island, Alaska, Usa, A Geographically Remote Record Of Indigenous Diplopoda, Rowland M. Shelley, Michael F. Medrano, Kristiina Ovaska

Insecta Mundi

With documentation of an unidentifiable adult female and juvenile Tingupidae (Chordeumatida), Kodiak Island, Alaska, becomes the westernmost indigenous diplopod locality in North America including continental islands. The northernmost and most proximate locality, Yakutat, lies ca. 935 mi (1,496 km) to the eastnortheast, while Haines, the type locality of Tingupa tlingitorum Shear and Shelley, some 1,196 mi (1,914 km) in this direction, is the most proximate familial site. Kodiak is also one of the most remote indigenous milliped localities in the Pacific, the most proximate ones to the west and south, Kamchatka, Russia, and the Hawaiian Islands, United States, being over …

Chemistry In Second Life, Andrew Lang, Jean-Claude Bradley

College of Science and Engineering Faculty Research and Scholarship

This review will focus on the current level on chemistry research, education, and visualization possible within the multi-user virtual environment of Second Life. We discuss how Second Life has been used as a platform for the interactive and collaborative visualization of data from molecules and proteins to spectra and experimental data. We then review how these visualizations can be scripted for immersive educational activities and real-life collaborative research. We also discuss the benefits of the social networking affordances of Second Life for both chemists and chemistry students.

Investigating Biological Activity Spectrum For Novel Styrylquinazoline Analogues, James Carroll, Jim O'Mahony, Aidan Coffey

Department of Biological Sciences Publications

In this study, series of ring-substituted 2-styrylquinazolin-4(3H)-one and 4-chloro-2-styrylquinazoline derivatives were prepared. The syntheses of the discussed compounds are presented. The compounds were analyzed by RP-HPLC to determine lipophilicity. They were tested for their inhibitory activity on photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the synthesized compounds was also performed against four mycobacterial strains and against eight fungal strains. Several compounds showed biological activity comparable with or higher than that of the standard isoniazid. It was found that the electronic properties of the R substituent, and not the total lipophilicity of the …

What Distinguishes Weight-Loss Maintainers From The Treatment-Seeking Obese? Analysis Of Environmental, Behavioral, And Psychosocial Variables In Diverse Populations, Suzanne Phelan, Tao Liu, Amy Gorin, Michael Lowe, Joseph Hogan, Joseph Fava, Rena R. Wing

Kinesiology and Public Health

Background Understanding the factors that influence successful weight control is critical for developing interventions.
Purpose The purpose of the study was to provide a comprehensive understanding of the role of psychosocial, environmental, and behavioral variables in distinguishing weight-loss maintainers (WLM) from treatment-seeking obese (TSO).
Methods WLM (n=167) had lost ≥10% of their maximum body weight, had kept the weight off for ≥5 years, and were now of normal weight. TSO-1 and TSO-2 had a history of dieting and body mass index ≥25. TSO-1 was predominantly Caucasian; TSO-2 was predominantly African-American. Bayesian model averaging was used to identify the …

The Pentameric Vertex Proteins Are Necessary For The Icosahedral Carboxysome Shell To Function As A Co2 Leakage Barrier, Fei Cai, Balaraj B. Menon, Gordon C. Cannon, Kenneth J. Curry, Jessup M. Shively, Sabine Heinhorst

Faculty Publications

Background

Carboxysomes are polyhedral protein microcompartments found in many autotrophic bacteria; they encapsulate the CO₂ fixing enzyme, ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO) within a thin protein shell and provide an environment that enhances the catalytic capabilities of the enzyme. Two types of shell protein constituents are common to carboxysomes and related microcompartments of heterotrophic bacteria, and the genes for these proteins are found in a large variety of bacteria.

Methodology/Principal Findings

We have created a Halothiobacillus neapolitanus knockout mutant that does not produce the two paralogous CsoS4 proteins thought to occupy the vertices of the icosahedral carboxysomes and related microcompartments. Biochemical …

A Heteroskedastic Error Covariance Matrix Estimator Using A First-Order Conditional Autoregressive Markov Simulation For Deriving Asympotical Efficient Estimates From Ecological Sampled Anopheles Arabiensis Aquatic Habitat Covariates, Benjamin G. Jacob, Daniel A. Griffith, Ephantus J. Muturi, Erick X. Caamano, John I. Githure, Robert J. Novak

All Peer-Reviewed Publications

Background. Autoregressive regression coefficients for Anopheles arabiensis aquatic habitat models are usually assessed using global error techniques and are reported as error covariance matrices. A global statistic, however, will summarize error estimates from multiple habitat locations. This makes it difficult to identify where there are clusters of An. arabiensis aquatic habitats of acceptable prediction. It is therefore useful to conduct some form of spatial error analysis to detect clusters of An. arabiensis aquatic habitats based on uncertainty residuals from individual sampled habitats. In this research, a method of error estimation for spatial simulation models was demonstrated using autocorrelation indices and …

Body Composition Assessment Methods: A Systematic Review And Recommendations, Ygnacio Lopez Iii, Scherezade Mama, Penny Wilson, Rebecca E. Lee

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

Physical Activity Resource Attributes And Obesity In Low-Income African Americans Living In Public Housing, Kristen M. Mcalexander, Jorge A. Banda, Joshua W. Mcalexander, Rebecca E. Lee

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

Depression And Percent Body Fat Are Associated With Binge Eating In A Community Sample Of African American And Hispanic Women, Penny Wilson, Paula C. Rhode, Daniel P. O'Connor, Rebecca E. Lee

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

Daily Variation In Monocyte Subsets And Toll-Like Receptor 2 And 4 Expression In Young And Old Mice, Whitney L. Breslin, Kelley Strohacker, Brian K. Mcfarlin

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

Voluntary Exercise Causes Greater Weight Loss In Obese Mice, Katie C. Carpenter, Kelley Strohacker, Whitney L. Breslin, Mark R. Morrison, Joseph Potucek, Nadia Agha, Richard J. Simpson Phd, Thomas W. Lowder Phd, Brian K. Mcfarlin Phd

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

Regular Physical Activity Is Correlated With A Reduced Frequency Of Senescent T-Lymphocytes In Middle-Aged Men, Guillaume Spielmann, Brian K. Mcfarlin, Paula J.W. Smith, Keith Guy, Richard J. Simpson

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

Age-Related Differences In Monocyte Toll-Like Receptor 2/4 And Cd54 Expression In Mice, Kelley Strohacker, Whitney L. Breslin, Brian K. Mcfarlin

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

The Muscular Benefits Of 13 Weeks Of Functional Electrical Stimulation Cycling After Spinal Cord Injury, John Ward, Stanley Fisher, Adam Thrasher

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

The Relationship Between Body Image And Physical Activity In African American Women, Scherezade K. Mama, Beth E. Quill Mph, Maria E. Fernandez-Esquer Phd, Jacqueline Y. Reese-Smith, Jorge A. Banda, Rebecca E. Lee

International Journal of Exercise Science: Conference Proceedings

No abstract provided.

Genetic Insulator For Preventing Influence By Another Gene Promoter, Susheng Gan, Mingtang Xie

Plant and Soil Sciences Faculty Patents

A 16 bp polynucleotide sequence of Arabidopsis thaliana is a genetic insulator that can effectively isolate a transgene from positional effects of neighboring gene activities in transgenic plant cells.

Integral Membrane Proteins Brr6 And Apq12 Link Assembly Of The Nuclear Pore Complex To Lipid Homeostasis In The Endoplasmic Reticulum, Christine A. Hodge, Vineet Choudhary, Michael J. Wolyniak, John J. Scarcelli, Roger Schneiter, Charles N. Cole

Dartmouth Scholarship

Cells of Saccharomyces cerevisiae lacking Apq12, a nuclear envelope (NE)-endoplasmic reticulum (ER) integral membrane protein, are defective in assembly of nuclear pore complexes (NPCs), possibly because of defects in regulating membrane fluidity. We identified BRR6, which encodes an essential integral membrane protein of the NE-ER, as a dosage suppressor of apq12 Delta. Cells carrying the temperature-sensitive brr6-1 allele have been shown to have defects in nucleoporin localization, mRNA metabolism and nuclear transport. Electron microscopy revealed that brr6-1 cells have gross NE abnormalities and proliferation of the ER. brr6-1 cells were hypersensitive to compounds that affect membrane biophysical properties and to …

Systematics And Biogeography Of The Didymopanax Group Of Schefflera (Araliaceae), Pedro Fiaschi

Theses and Dissertations

Schefflera is the largest genus in the angiosperm family Araliaceae, with about 900 species, of which c. 300 belong to five subgeneric groups in the Neotropical region. Previous phylogenetic studies of Schefflera have been limited to a small number of species from this region, and very little is know about phylogenetic relationships in the Brazilian-centered Didymopanax group of this genus. Therefore, to gain a better understanding of the diversity and evolution of the Didymopanax group of Schefflera, I investigated the systematics of these plants in the broader context of the entire Neotropical clade. The main goals were (1) to investigate …

Sphingolipid-Induced Activation Of The Volume-Sensitive Cl− Current Is Mediated By Mitochondrial Reactive Oxygen Species, Frank Raucci

Theses and Dissertations

Swelling-activated Cl− current (ICl,swell) is an outwardly-rectifying current that plays an important role in cardiac electrical activity, cellular volume regulation, apoptosis, and acts as a potential effector of mechanoelectrical feedback. Persistent activation of ICl,swell has been observed in a number of models of cardiovascular disease. Previously we showed that angiotensin II (Ang II), endothelin-1 (ET-1), endothelial growth factor receptor (EGFR), and reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and mitochondria are involved in the activation of ICl,swell by both osmotic swelling and Beta1 integrin stretch. Sphingolipid metabolism is modulated in several cardiopathologies and because sphingolipids are bioactive lipids …

Multiple Models Can Concurrently Explain Fatigue During Human Performance, C. Matthew Laurent†, Matt Green‡

International Journal of Exercise Science

One of the most commonly and thoroughly studied paradigms of human performance is fatigue. However, despite volumes of research there remains considerable controversy among scientists regarding definitive conclusions about the specific mechanism(s) contributing to fatigue. Within the literature there are three primary yet distinctly different governing ideas of fatigue; the traditionally referenced central model and peripheral model as well as the emerging central governor model (CGM). The CGM has recently been advocated by a limited number of researchers and is suggestive of a more integrative model of fatigue when compared the traditional peripheral and central models. However, more work is …

Determination Of Force Corresponding To Maximal Lactate Steady State In Tethered Swimming, Marcelo Papoti‡, Ricardo Vitório†, Sérgio A. Cunha†, Gustavo G. Araújo†, Adelino S.R. Silva‡, Vanessa Santhiago‡, Luiz E.B. Martins‡, Claudio A. Gobatto‡

International Journal of Exercise Science

The main aim of the present investigation was to verify if the aerobic capacity (AC) measured in tethered swimming corresponds to the maximal lactate steady state (MLSS) and its correlation with 30 min and 400m free style swimming. Twenty-five swimmers were submitted to an incremental tethered swimming test (ITS) with an initial load of 20N and increments of 10N each 3min. After each stage of 3min, the athletes had 30s of interval to blood sample collections that were used to measure blood lactate concentrations ([La-]). The ACBI was determined by the abrupt increase in [La-] versus force (F). The points …

The Short-Term Effect Of Whole Body Vibration Training On Sprint Start In Collegiate Athletes, Brad Roberts*, Iain Hunter‡, Ty Hopkins‡, Brent Feland‡

International Journal of Exercise Science

Whole body vibration (WBV) is characterized by a vibratory stimulus emitted throughout the body through the use of a vibrating platform on which the subject stands. Studies have shown over 30% increases in maximal explosive strength such as maximal speed biceps curl as well as increases in maximum dynamic force such as maximal sitting bench pull as the result of vibration. The purpose of this study was to investigate the effects of short term whole-body vibration on sprint starts among collegiate track athletes. On the first day eleven subjects were randomly assigned to either a non-vibration or vibration group for …

Evaluation Of Hand-To-Hand Bioelectrical Impedance Analysis For Estimating Percent Body Fat In Young Adults, Aaron M. Weaver*, Ashley C. Hill*, Joseph L. Andreacci‡, Curt B. Dixon‡

International Journal of Exercise Science

Purposes were to (a) to examine the validity and precision of a hand-to-hand bioelectrical impedance analyzer (HBIA) and (b) to determine the effect of an acute sub-maximal aerobic exercise bout on HBIA percent body fat (%BF) measures. Forty-one young adults (21 women; 20 men) visited the laboratory for body composition assessment on two separate occasions. During the control session, %BF was assessed by HBIA twice, before and immediately after 30 min of rest, and once by air-displacement plethysmography (ADP), using the BOD POD, which was considered the criterion method for comparison. During the exercise session, HBIA %BF measurements were determined …