Life Sciences Commons^™

Epigenetic Reprogramming In Pediatric Tumors Predicts Active Pathways In The Tumor Microenvironments, Noah Moffat, Clark Tolbert, Colin Wessman, Matthew H. Bailey

Library/Life Sciences Undergraduate Poster Competition 2025

Figure 1: We collected samples from five different studies that analyzed and generated spatial transcriptomic data from adult and pediatric brain tumors1-4.

Engineering Chromoprotein Variants With New Colors, Anna Bowman, Joel S. Griffitts, Kyler Fullmer

Library/Life Sciences Undergraduate Poster Competition 2025

No abstract provided.

Can Spatiotemporal Gait Parameters Predict State Anxiety?, Stephanie M. Cotariu, Ashlyn M. Jendro, Yale B. Hughes, Abigail C. Schmitt

2025 Honors Symposium

Background: Anxiety is one of the most experienced mental health disorders. Recent research has suggested a relationship between gait parameters and anxiety, however the disparity in measurement methodologies of both anxiety and gait makes it difficult to draw broad conclusions. Better understanding the relationship between anxiety and gait mechanics creates opportunity for a more holistic understanding of the interaction between mental health, functional capacity, and quality of life. Purpose: The purpose of this study is to evaluate if spatiotemporal gait parameters measured on a pressure-sensing walkway are related to anxiety.

Comparing Gait Patterns Of Individuals With And Without Cancer, Anna C. Gardner, Abigail C. Schmitt, Ashlyn M. Jendro, Nicholas P. Greene

2025 Honors Symposium

This study investigates the effects that cancer has on gait variables focusing on gait speed, step length, and stride width, and compares participants with cancer to participants without known disease.

Sports Injury Prevention - Epidemiological Analysis Of Concussion Mechanisms In Female Soccer Players: A Review Of Neiss Data (2020–2023), Caroline A. Bertalotto

2025 Honors Symposium

Background/Introduction: Concussions are a significant concern in women’s soccer, with many studies showing that women have a higher rate of having them than compared to men. The number of concussions in athletes have raised concerns about long-term health and calls for a deeper look into ways to prevent them from occurring. Purpose: The purpose of this study is to review the epidemiological data related to the mechanisms of concussions as a result of soccer, specifically within female participants.

Icipe Monthly Digest – Volume 1, Issue 1, January 2025, International Centre Of Insect Physiology And Ecology (Icipe)

icipe Newsletters

No abstract provided.

Atypical Stroke-Like Presentation In A Patient With Mucormycosis, Joseph Crutison, Yasser El-Daour, Dominique Pean

Gulf Coast Division GME Research Day 2025

No abstract provided.

What Are The Genetic Influences Of Alcohol Sensitivity And Alcohol Metabolism? A Narrative Review Of Human Studies, Erwin Murray, Karen G. Chartier Phd, Msw

UROP Posters

Background: Alcohol sensitivity and alcohol metabolism are two phenotypes associated with alcohol use disorder (AUD) influenced by genetics. This narrative review aims to answer “What are the genetic influences of alcohol sensitivity and alcohol metabolism?” to gain a better understanding of the genetic aspects of AUD.

Methods: A database search was performed in PubMed. Empirical human genetic studies published between 2009 and 2025 that focused on alcohol sensitivity (measured by the Self-Rating of the Effects of Alcohol scale) or alcohol-metabolizing genes were eligible for review. Studies were screened to determine inclusion for the current review.

Findings: Fifteen …

Effects Of Gas Exchange Rates Between C3 And C4 Plant Species, Samantha L. Moya, Mollie Ouk, Aisha Goni

UROP Posters

Spinach and basil (C3 plants) were compared with corn (C4 plant) to

explore how photosynthetic pathways affect CO2 consumption. Corn

seeds were obtained and planted in Miracle-Gro® soil to be observed

over the duration of a month. Leaves (starting from 3,4, and 10) from

each plant were then taken and placed into a bottle and closed off

with a CO2 gas probe that measured levels of carbon dioxide in ppm.

Spinach and basil leaves were used as a comparison for measuring

the rate of CO2 concentration. This is done to compare the gas

exchange rates between C3 and C4 plants. …

Science, Physiology, And Nutrition For The Nonscientist, Judi S. Morrill

Open Educational Resources

A wonderful blend of physiology, nutrition, biochemistry, genetics, biology, evolution, chemistry--what we all need to know as informed citizens. A basic knowledge of the life sciences and how our bodies work--to promote our own good health, especially as we're bombarded with misleading advertisements, soundbites, and the like. DNA fingerprinting, calorie requirements, dietary advice, genetic engineering (including gene editing with CRISPR cas9)--all in an easy-to understand book.

Carbohydrate Counting: Traditional Filipino Food Lists For Management And Prevention Of Diabetes Mellitus, Ashwini Wagle

Open Educational Resources

The Carbohydrate Counting tool was created to address the specific dietary needs of the Filipino population. It is an original intellectual work by Ashwini Wagle, Ed.D., MS, RD, Chair of the Department of Nutrition, Food Science, and Packaging at San Jose State University (SJSU).

The development of this tool was made possible through the collaboration and support of several contributors. Serena Starr, MS; Justine Martinez Cuaresma, MS, RD; Nazli Goudarzi, MS; Leah Olaivar; and Joe Johnston—a graduate student in the Department—played integral roles in the project. Their contributions included verifying the authenticity of traditional foods, designing culturally appropriate meal plans, …

2025 Annual Report, Tennessee. Division Of Forestry And Tennessee. Department Of Agriculture

Forestry Annual Reports

This annual report presents an overview of Tennessee Forestry Commission programs and management.

René Dubos: An Annotated Bibliography, Carol L. Moberg

René Dubos: An Annotated Bibliography

René Dubos (1901–1982), a prominent 20th century scientist, humanist, and philosopher, was a prolific author. Affiliated for more than 50 years with The Rockefeller Institute for Medical Research/The Rockefeller University, his studies ranged from antibiotics and the role of bacteria in human diseases to formulating broad ecological and environmental questions affecting human health and disease. His seminal writings explore a lifelong belief that a living organism—whether microbe, human being, society, or the Earth itself—could be understood only through its relationships with everything else.

This comprehensive bibliography of more than a thousand works by René Dubos includes brief annotations for each …

Wa Insecticide Guide 2025 - Autumn Winter, Rebecca Severtson

PestFacts WA

Registered chemicals for broadacre crops in Western Australia.

The insecticides listed in the tables within this guide can be used on any crop appearing on the chemical label, if the rate used does not exceed the highest rate that is registered for use on that crop.

There are many products with different trade names that contain the same active ingredient. This list is not exhaustive and does not imply any specific recommendations of brand names.

Principles Of Biomedical Research, Faina Linkov, Matthew C. Kostek

Open Education Materials

HLT 430/530

CC BY-NC-SA

Analysis Of Mutations In Bmpr2 Gene Associated With Hypertension, Elaine Vanterpool, Keury C. Ruiz

Student Posters

Mutations in the BMPR2 gene are primarily recognized for their role in the development of blood vessels, however, they have also been associated with the pathogenesis of high blood pressure, specifically in regards to altered vascular function and the endothelial cell signal. Early detection and targeted treatment, as well as lifestyle changes, are pivotal in reducing the risk of serious complications associated with high blood pressure. Recent genetic research and personalized medicine have demonstrated the potential to enhance the prevention, diagnosis, and treatment of high blood pressure, particularly through the identification of genetic mutations in the BMPR2 gene.

Analyzing The Inhibition Of Chemical Compounds On Protease In P. Aeruginosa, Elaine Vanterpool

Student Posters

Pseudomonas aeruginosa is a gram-negative, bacillus-shaped opportunistic pathogen, notorious for invading immunocompromised individual leading to secondary infections. These opportunistic microbes typically are implicated mild to more severe infections including burn or wound infections to more serious systemic infections. The bacterium Ps. aeruginosa utilizes a variety of virulence factors to enhance the pathogenicity of the organism. Virulence factors secreted by Ps. aeruginosa include its pili, adhesins, capsule, exotoxin A, and lipopolysaccharide (LPS). The proteases produced by Ps. aeruginosa are powerful virulence factors that can lead to tissue destruction and immune invasion. It is imperative that we find ways of regulating the …

Gata1 Gene Variants Associated With Myeloproliferative Syndrome And Its Impact On Hematopoiesis, Elaine Vanterpool, Marliza Mendez Del Orbe

Student Posters

Myeloproliferative syndrome (MPS) are rare blood cancers that originate from an abnormal mutation in a stem cell within the bone marrow, leading to excessive production of red blood cells, white blood cells, or platelets. These disorders affect approximately 20,000 individuals annually in the United States, with around 295,000 people currently living with the condition. The purpose of this study is to identify and assess the pathogenicity of GATA1 gene variants associated with MPS.

An Analysis Of Ftl Variants Associated With Cataracts Disease, Elaine Vanterpool, Joram Kisaka

Student Posters

Cataract is an eye disease that clouds the eye's natural lens, which is used to focus light on the retina. This eye disease causes symptoms such as blurry vision, double vision, sensitivity to light, and difficulty seeing at night. Cataracts are tied to the gene called Ferritin Light Chain (FLT), which is found in both prokaryotes and eukaryotes and plays a role in encoding the light subunits of the ferritin protein. The purpose of this research study was to identify the Ferritin Light Chain mutations that cause cataracts.

An Examination Of Lacc1 Variants Linked To Rheumatoid Arthritis, Elaine Vanterpool, Rochelle Gunter

Student Posters

Rheumatoid arthritis is an inflammatory disease with an annual diagnosis rate of 70 cases per 100,000 people. This is a disease that is usually identified by the abnormal entry of immune cells, such as B lymphocytes, T lymphocytes, and innate lymphoid cells, into the synovial tissues of the joints. When these immune cells infiltrate the joints, they can become too active, thereby contributing to the chronic inflammatory response characteristic of the disease. The objective of this study is to identify and evaluate the pathogenic potential of LACC1 variants implicated in the pathogenesis of arthritis. Simple ClinVar identified LACC1 as a …

The Duality Of The Bard1 Gene, Elaine Vanterpool, Khadra Burden

Student Posters

Breast cancer is the 2nd most diagnosed cancer in women in the United States (Mayo Clinic). Cancer is the overproduction of cells. In other words, cancer-infected cells continue to grow and may cause large growths called tumors. Although there have been innumerable strides in breast cancer research, the exact cause for breast cancer is not yet known (Mayo Clinic). It is believed that factors such as family history of the disease, early menstruation age, and obesity can increase an individual’s chances of having breast cancer. One of the well-known genes associated with breast cancer is BRCA1. A much less researched …

An Analysis Of Androgen Receptor (Ar) Variants In Breast Cancer, Elaine Vanterpool, Jordae Smith

Student Posters

The androgen receptor (AR) is a steroid-hormone activated transcription factor that regulates gene expression in response to testosterone and dihydrotestosterone (DHT). While AR has been extensively studied in prostate cancer, emerging research suggests its role in breast cancer, particularly in estrogen receptor-positive (ER-positive) and triple-negative breast cancer (TNBC). This study investigates AR variants associated with breast cancer, assessing their pathogenicity and potential impact on prognosis and treatment.

Study Of Myl3 Mutation Variants And Their Association With Cardiac Amyloidosis, Elaine Vanterpool, Kyla Tucker

Student Posters

Cardiac Amyloidosis is a rare serious, pathological, clinical progressive disease that is caused by the buildup of amyloid fibrils deposited at the cardiac level. The excess amyloid fibrils deposited in the myocardium leads to this critical condition. Cardiac amyloidosis is best treated when diagnosed in its initial stages. The purpose of this study was to identify and assess the clinical significance and pathogenicity of the Myosin light chain 3 (MYL3) its variants, and the potential link to cardiac amyloidosis. For this study, Simple ClinVar was utilized to identify MYL3 as one of the genes correlated with Cardiac Amyloidosis and variants. …

Silver Nanoparticles And Natural Compounds Can Modulate Proteolytic Activities Of Escherichia Coli, Elaine Vanterpool

Student Posters

Escherichia coli (E. coli) is a gram-negative, facultative anaerobic bacterium that naturally resides in the human gastrointestinal tract as a commensal microorganism. While non-pathogenic strains contribute to digestion and vitamin production, certain pathogenic strains can cause a wide range of diseases, from mild gastrointestinal discomfort to severe illness. A key factor in its pathogenicity is the production of protease enzymes that break down proteins which play a crucial role in bacterial survival and virulence. This study aimed to investigate the effectiveness of different antibacterial compounds in inhibiting the function of both secreted and cell-associated E. coli protease activity.

Analysis Of Kcnj2 Variants Associated With Wolff-Parkinson-White Syndrome, Elaine Vanterpool, Kerenlaime Bautista

Student Posters

Wolff-Parkinson-White (WPW) syndrome is a cardiac disorder characterized by an accessory electrical pathway, leading to tachycardia and arrhythmias. It is diagnosed via electrocardiogram (ECG), showing a shortened PR interval and delta wave. WPW is typically managed with medications, catheter ablation, or surgery. Although primarily caused by anatomical anomalies, emerging research suggests genetic factors, including ion channel mutations, may contribute to the condition. The KCNJ2 gene encodes an inward-rectifier potassium channel critical for cardiac excitability. Mutations in KCNJ2 are linked to Andersen-Tawil syndrome, a disorder featuring arrhythmias and muscle weakness, raising questions about its role in WPW. This study investigates whether …

An Analysis Of Htt Involvement In Huntington’S Disease, Elaine Vanterpool, Micah Andrews

Student Posters

Huntington's disease is a neurodegenerative disorder characterized by loss of striatal neurons. These striatal neurons are essential in cognition, motor function, decision-making, motivation, reinforcement, and reward perception. Affected individuals may show symptoms such as isolation, lack of motivation, depression, mood swings, and personality changes. This study’s purpose is to analyze and highlight the variants of the HTT gene in the pathogenesis of Huntington’s disease.

An Analysis Of Dnajc13 Variants Associated With Parkinson’S Disease, Elaine Vanterpool, Rhadames M. Batista-Mendez

Student Posters

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons, leading to motor impairments such as tremors, rigidity, and postural instability. Affecting millions worldwide, PD has been linked to both genetic and environmental factors. This study aims to identify and assess the pathogenicity of DNAJC13 variants associated with Parkinson's disease.

An Analysis Of Dguok Variants Associated With Mitochondrial Dna Depletion Syndrome, Elaine Vanterpool, Ethan Harris

Student Posters

Mitochondrial DNA Depletion Syndrome(MDDS) is a clinically heterogeneous group of autosomal recessive mitochondrial disorders that reduces the number of mitochondrial DNA (mtDNA) in the affected cells. This disease is characterized by the disruption of hepatocytes, skeletal muscle, and cerebral function. This study's purpose is to identify and assess the pathogenicity of DGUOK variants associated with MDDS.

Analysis Of Dmd Variants Associated With Duchenne Muscular Dystrophy, Elaine Vanterpool, K’Sia Byass

Student Posters

Duchenne Muscular Dystrophy is an X-linked recessive disorder that causes muscle weakness. This disease is characterized by frequent falls, difficulty walking, running, jumping, or scoliosis. Duchenne Muscular Dystrophy 1 in every 5000 boys worldwide causes a gene tic mutation that prevents the production of dystrophin. This study aims to identify and assess the pathogenicity of DMD variants associated with Duchenne Muscular Dystrophy. Genetic mutations responsible for Duchenne Muscular Dystrophy have been reported. Studies regarding DMD and its specific role in causing Duchenne Muscular Dystrophy have been reported to be accurate and effective. X-linked inheritance patterns are applied to this disease's …

Investigating Alk, Phox2b, And Brca2 Gene In Relation To Neuroblastoma, Elaine Vanterpool, Joshua Henry

Student Posters

One of the biggest mysteries of cancer today is Neuroblastoma. Neuroblastomas are malignancies originating from the early nerve cells of the sympathetic nervous system, often known as neuroblasts. Neuroblasts can occur anywhere throughout the sympathetic nervous system. About one-third of infants are diagnosed with neuroblastoma by the time they turn one year old and the disease frequently starts in infancy. By the age of five, almost 75% have a diagnosis. Neuroblastomas are present in some newborns, but they are not identified until later, when the child or infant starts exhibiting symptoms. Adult cases of NB are quite rare. The majority …