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Articles 241 - 270 of 1535
Full-Text Articles in Life Sciences
Hepatoprotective Activity Of Curcuma Xanthorrhiza Roxb. Paracetamol-Induced Liver Damage In Rats And Correlation With Their Chemical Compounds, Suwijiyo Pramono, Fitriana Hayyu Arifah, Fitrawan Hernuza Pribadi, Agung Endro Nugroho
Hepatoprotective Activity Of Curcuma Xanthorrhiza Roxb. Paracetamol-Induced Liver Damage In Rats And Correlation With Their Chemical Compounds, Suwijiyo Pramono, Fitriana Hayyu Arifah, Fitrawan Hernuza Pribadi, Agung Endro Nugroho
The Thai Journal of Pharmaceutical Sciences
Paracetamol is a widely used drug, but at high dose, it can produce undesirable side effects such as hepatotoxicity. Curcuma xanthorrhiza Roxb. is the one of Indonesian medicinal plants that traditionally used to treat liver disorders. The present study .
Dna Barcoding For Authentication Of The Endangered Plants In Genus Aquilaria, Worathat Thitikornpong, Chanida Palanuvej, Nijsiri Ruangrungsi
Dna Barcoding For Authentication Of The Endangered Plants In Genus Aquilaria, Worathat Thitikornpong, Chanida Palanuvej, Nijsiri Ruangrungsi
The Thai Journal of Pharmaceutical Sciences
Agarwood is a type of wood that is used in traditional Thai medicines and has been applied in several recipes; in particular, this wood is considered as a costly resinous non-wood product. However, the morphological characteristics of the plant in the ge.
Bioactivities Of Organic Riceberry Broken Rice And Crude Riceberry Rice Oil, Vijitra Luang-In, Manatchanok Yotchaisarn, Issaraporn Somboonwatthanakul, Sirirat Deeseenthum
Bioactivities Of Organic Riceberry Broken Rice And Crude Riceberry Rice Oil, Vijitra Luang-In, Manatchanok Yotchaisarn, Issaraporn Somboonwatthanakul, Sirirat Deeseenthum
The Thai Journal of Pharmaceutical Sciences
Objectives: Riceberry broken rice (RBR) and crude riceberry rice oil (CRO) are inevitable by-products generated from organic rice process in Thailand for several tons per year with low value. The aims of this work were to determine gamma-oryzanol content.
Effects Of Age, Hydration Level, And Cosmetic Treatment On Skin Mechanical Properties Of Thai, Anyarporn Tansirikongkol
Effects Of Age, Hydration Level, And Cosmetic Treatment On Skin Mechanical Properties Of Thai, Anyarporn Tansirikongkol
The Thai Journal of Pharmaceutical Sciences
Purpose: Age and skin hydration influence skin mechanical properties. However, correlation between hydration improved by cosmetic and mechanical properties is uncertain. This study aimed to investigate the relationship between age, intrinsic skin hydrati.
Antiproliferative Effects Of Pereskiopsis Diguetii, Caralluma Speciosa And Euphorbia Ritchiei Hydroalcoholic Extract, Tossawan Jitwasinkul, Purin Charoensuksai
Antiproliferative Effects Of Pereskiopsis Diguetii, Caralluma Speciosa And Euphorbia Ritchiei Hydroalcoholic Extract, Tossawan Jitwasinkul, Purin Charoensuksai
The Thai Journal of Pharmaceutical Sciences
To date, cancers remain to be global health problem. The toxicity and the emergence of chemotherapy resistance of currently prescribed anticancer agents highlight the need for the discovery and the development of novel anticancer drugs. The previous succ.
Development And Validation Of Hptlc And Lc Ms-Ms Method For Estimation Of Terizidone In Pharmaceutical Dosage Form, Ritesh P. Bhole, Sonali Phadke
Development And Validation Of Hptlc And Lc Ms-Ms Method For Estimation Of Terizidone In Pharmaceutical Dosage Form, Ritesh P. Bhole, Sonali Phadke
The Thai Journal of Pharmaceutical Sciences
The estimation of Terizidone in pharmaceutical dosage form by using High Performance Thin Layer Chromatography was done using CAMAG HPTLC system. The separation was achieved using precoated silica gel 60 F254 aluminium plates with mobile phase Toluene: n.
Evaluating The Effect Of Donepezil On Depression And Obsessive–Compulsion Disorder In Mice Models And Proposing The Mechanism Involved, Azadeh Mesripour, Valiollah Hajhashemi, Shahrzad Rezaie
Evaluating The Effect Of Donepezil On Depression And Obsessive–Compulsion Disorder In Mice Models And Proposing The Mechanism Involved, Azadeh Mesripour, Valiollah Hajhashemi, Shahrzad Rezaie
The Thai Journal of Pharmaceutical Sciences
Introduction: Considering that donepezil (DPZ) is commonly prescribed for Alzheimer's disease patients, the aim of the present study was evaluating DPZ antidepressant effect and introducing the possible mechanism. Therefore nicotinic (mecamylamine) and m.
Anti-Hyperglycemic Effect And Subchronic Toxicity Of The Combined Extract From Sattagavata- Mathurameha -Tubpikarn Anti-Diabetic Herbal Formulae, Penchom Peungvicha
Anti-Hyperglycemic Effect And Subchronic Toxicity Of The Combined Extract From Sattagavata- Mathurameha -Tubpikarn Anti-Diabetic Herbal Formulae, Penchom Peungvicha
The Thai Journal of Pharmaceutical Sciences
The three herbal formulae (Sattagavata, Mathurameha, Tubpikarn) were prescribed to diabetic patients for a long times and they included Sattagavata for circulatory system promotion, Mathurameha for diabetics and Tubpikarn for hepatoprotection with less s.
Validated Thin-Layer Chromatography-Densitometric Method For Simultaneous Determination Of Piperine And Plumbagin In “Benjakul” Thai Polyherbal Formulation And Its Antioxidant Activities, Savita Chewchinda, Pattamapan Lomarat, Pongtip Sithisarn
Validated Thin-Layer Chromatography-Densitometric Method For Simultaneous Determination Of Piperine And Plumbagin In “Benjakul” Thai Polyherbal Formulation And Its Antioxidant Activities, Savita Chewchinda, Pattamapan Lomarat, Pongtip Sithisarn
The Thai Journal of Pharmaceutical Sciences
The purpose of this study was to evaluate antioxidant activity and quantitative analysis of piperine and plumbagin content in “Benjukul (BEN)” Thai polyherbal formulation by TLC densitometric method. BEN was recognized in the list of herbal medicinal...
Antihypercholesterol Activity Of Costus Speciosus Water Extract, Hari Susanti, Subagus Wahyuono, Ratna Asmah Susidarti, Ika Puspita Sari
Antihypercholesterol Activity Of Costus Speciosus Water Extract, Hari Susanti, Subagus Wahyuono, Ratna Asmah Susidarti, Ika Puspita Sari
The Thai Journal of Pharmaceutical Sciences
Hypercholesterol is one of cause of cardiovascular disease. Costus speciosus is known empirically as an antihypercholesterol remedy. The study was conducted to determine the effect of water extract of Costus speciosus (CS) on cholesterol blood serum leve.
Characterization Of Lactic Acid Producing Bacillus Coagulans Strains With Their Antibacterial Activity And L-Lactic Acid Production, Vasana Tolieng
Characterization Of Lactic Acid Producing Bacillus Coagulans Strains With Their Antibacterial Activity And L-Lactic Acid Production, Vasana Tolieng
The Thai Journal of Pharmaceutical Sciences
Objectives: Screening of antibacterial activity, identification, and L-lactic acid production of spore forming Bacillus isolates. Materials and methods: Fourteen Bacillus isolates were characterized based on their phenotypic characteristics and 16SrRNA .
Cost-Effectiveness Analysis Of Aripiprazole Compared With Risperidone In Treatment Of Acute Schizophrenia Patients In Thailand, Wiwat Thavornwattanayong
Cost-Effectiveness Analysis Of Aripiprazole Compared With Risperidone In Treatment Of Acute Schizophrenia Patients In Thailand, Wiwat Thavornwattanayong
The Thai Journal of Pharmaceutical Sciences
OBJECTIVES: Schizophrenia is the third leading cause of loss of life years in Thailand. Currently, aripiprazole is the latest drug for the treatment of acute schizophrenia in Thailand but its cost-effectiveness has not been studied. The purpose of this s.
Virtual Screening For Novel 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitors: A Shape-Based Search Approach, Prasan Tangyuenyongwatana, Wandee Gritsanapan
Virtual Screening For Novel 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitors: A Shape-Based Search Approach, Prasan Tangyuenyongwatana, Wandee Gritsanapan
The Thai Journal of Pharmaceutical Sciences
A virtual screening study with ArgusLab 4.0.1 was performed on 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), the second enzyme in the methyl erythritol phosphate pathway in isoprenoids production which is present in malarial parasite Plasmodium .
Chemical Compositions And Repellent Activity Of Eucalyptus Tereticornis And Eucalyptus Deglupta Essential Oils Against Culex Quinquefasciatus Mosquito, Rini Pujiarti, Rini Pujiarti
Chemical Compositions And Repellent Activity Of Eucalyptus Tereticornis And Eucalyptus Deglupta Essential Oils Against Culex Quinquefasciatus Mosquito, Rini Pujiarti, Rini Pujiarti
The Thai Journal of Pharmaceutical Sciences
Eucalyptus oils have distinctive smell that not preferably by mosquito and able to repellent mosquito. This research was evaluated chemical compositions and repellent activity of Eucalyptus tereticornis and Eucalyptus deglupta oils against C. quinquefasc.
Time-Kill Study Of The In Vitro Antimicrobial Activity Of Tedizolid Against Methicillin-Resistant Staphylococcus Aureus, Tanawat Nunart, Tanitta Chatsuwan, Wanchai Treyaprasert
Time-Kill Study Of The In Vitro Antimicrobial Activity Of Tedizolid Against Methicillin-Resistant Staphylococcus Aureus, Tanawat Nunart, Tanitta Chatsuwan, Wanchai Treyaprasert
The Thai Journal of Pharmaceutical Sciences
To evaluate the in vitro antimicrobial activity of tedizolid against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) by time-kill curve experiments. Four bacterial strains were used in methicillin susceptibility tests, including M.
Effects Of Family Pharmacy Intervention On Clinical Outcomes In Primary Care Settings In Thailand, Wiwat Thavornwattanayong, Namfon Sribundit
Effects Of Family Pharmacy Intervention On Clinical Outcomes In Primary Care Settings In Thailand, Wiwat Thavornwattanayong, Namfon Sribundit
The Thai Journal of Pharmaceutical Sciences
Background Despite pharmaceutical care had positive effect on improving patient health, currently data fact sheet illustrate slightly increasing of uncontrolled diabetes and uncontrolled hypertension among Thai elderly. Family pharmacist applied more ef..
Vanillin Increases Stem Cell Signal And Cell Adhesion In Keratinocytes, Supak Taboonpong, Chayanin Kiratipaiboon, Preeyaporn Plaimee Phiboonchaiyanan, Premjit Junthongjin, Pornlert Trithossadech, Pithi Chanvorachote
Vanillin Increases Stem Cell Signal And Cell Adhesion In Keratinocytes, Supak Taboonpong, Chayanin Kiratipaiboon, Preeyaporn Plaimee Phiboonchaiyanan, Premjit Junthongjin, Pornlert Trithossadech, Pithi Chanvorachote
The Thai Journal of Pharmaceutical Sciences
Keratinocyte stem cells residing in the basal layer of the epidermis are thought to function in the process of the epidermis renewal and maintain the barrier property of the skin. This study has explored for the first time that vanillin, a natural compou.
Effect Of Different Production Variables On The Physical Properties Of Pellets Prepared By Extrusion-Spheronization Using A Multivariate Analysis, John Rojas
The Thai Journal of Pharmaceutical Sciences
The spheronization process has been widely used in recent years in multiparticulate oral formulations because it is a simple and rapid technology. It offers advantages over other dosage forms such as tablets due to the more uniform and predictable transp.
Docking, Synthesis, And Cytotoxic Activity Of N-4-Methoxybenzoyl-N’-(4-Fluorophenyl)Thiourea On Hela Cell Line, Anindi Lupita Nasyanka
Docking, Synthesis, And Cytotoxic Activity Of N-4-Methoxybenzoyl-N’-(4-Fluorophenyl)Thiourea On Hela Cell Line, Anindi Lupita Nasyanka
The Thai Journal of Pharmaceutical Sciences
Tiourea derivatives such as phenylthiourea, benzoyltiourea, tenovin, and many more have been reported as anticancer agent. In this study, we have done some initial step (docking, synthesis, and cytotoxic assay) to develop one of thiourea derivatives, N-4.
Enhancement Of Solubility And Dissolution Rate Of Quercetin With Solid Dispersion System Formation Using Hpmc Matrix, Dwi Setyawan
Enhancement Of Solubility And Dissolution Rate Of Quercetin With Solid Dispersion System Formation Using Hpmc Matrix, Dwi Setyawan
The Thai Journal of Pharmaceutical Sciences
Purpose : The aim of the present study was to obtain raw quercetin materials using solid dispersion system with better solubility and dissolution rate than pure quercetin. Methods: The solid dispersion of Quercetin-HPMC was prepared by solvent method. Su.
Gold Nanoparticle-Colocasia Gigantean Conjugates For Enhancing Cytotoxic Effect Against A375 Melanoma Cell Line, Amornpun Sereemaspun
Gold Nanoparticle-Colocasia Gigantean Conjugates For Enhancing Cytotoxic Effect Against A375 Melanoma Cell Line, Amornpun Sereemaspun
The Thai Journal of Pharmaceutical Sciences
Herbs are a prototype of traditional medicine for primary health care. Their knowledge is the basis of many modern medicinal discoveries. With the new invention of nanomaterials for biomedical applications, gold nanoparticles (AuNPs) have been proven to .
Determination Of Ethionamide In Pharmaceutical By Spectrophotometry Via Oxidation Reaction With Potassium Iodate, Nagib A.S. Qarah, Kanakapura Basavaiah
Determination Of Ethionamide In Pharmaceutical By Spectrophotometry Via Oxidation Reaction With Potassium Iodate, Nagib A.S. Qarah, Kanakapura Basavaiah
The Thai Journal of Pharmaceutical Sciences
Two new spectrophotometric methods are described for the determination of ethionamide (ETM) in pure and tablet forms. Method A is based on the oxidation of ETM by KIO3 in H2SO4 medium, and the in situ generated iodine is extracted into chloroform and mea.
In Vitro Antimicrobial Activity Of Antidesma Bunius Extracts On Oral Pathogenic Bacteria, Panicha Pongnaratorn, Prakasit Kuacharan, Vayura Kotsuno, Naruwat Pakdee, Pranee Sriraj, Jintana Sattayasai
In Vitro Antimicrobial Activity Of Antidesma Bunius Extracts On Oral Pathogenic Bacteria, Panicha Pongnaratorn, Prakasit Kuacharan, Vayura Kotsuno, Naruwat Pakdee, Pranee Sriraj, Jintana Sattayasai
The Thai Journal of Pharmaceutical Sciences
High antioxidant content of Antidesma bunius may lead to many beneficial pharmaceutical properties such as an anti-bacterial, anti-inflammatory and somatic cell decelerations, as well as cancer prevention. This study aimed at quantifying total phenolic c.
Analytical Method Development And Validation For Iron And Ascorbic Acid In Ferrous Bisglyciante Effervescent Tablets By Colorimetry And Rp-Hplc., Vasantharaju Sg
Analytical Method Development And Validation For Iron And Ascorbic Acid In Ferrous Bisglyciante Effervescent Tablets By Colorimetry And Rp-Hplc., Vasantharaju Sg
The Thai Journal of Pharmaceutical Sciences
A sensitive colorimetric and reverse phase high performance liquid chromatographic method was developed for estimation of total iron and ascorbic acid in ferrous bisglycinate effervescent tablets. A colorimetric method was developed for total iron us...
The Reform Of Drug Patent System In Thailand, Wanna Sriviriyanupap
The Reform Of Drug Patent System In Thailand, Wanna Sriviriyanupap
The Thai Journal of Pharmaceutical Sciences
Drug patent system has a direct impact on the health care cost and the access of the drugs of people. Previously, the drug patent system in Thailand encounters the problems both efficiency and quality of patent approval. This study aims to analyze the pr.
Effects Of The Standardized Extract Of Centella Asiatica Eca233 On Hepatic Phase Ii Drug-Metabolizing Enzymes In Rats, Pitchayapa Seeka, Nuansri Niwattisaiwong, Mayuree H. Tantisira, Songpol Chevapat, Kridsada Anuntawuttikul, Khemchat Apipalakul, Somsong Lawanprasert
Effects Of The Standardized Extract Of Centella Asiatica Eca233 On Hepatic Phase Ii Drug-Metabolizing Enzymes In Rats, Pitchayapa Seeka, Nuansri Niwattisaiwong, Mayuree H. Tantisira, Songpol Chevapat, Kridsada Anuntawuttikul, Khemchat Apipalakul, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
The standardized extract of C. asiatica ECa233 (ECa 233) was shown to possess neuroprotective and wound healing effects. The purpose of this study was to investigate effects ECa 233 on the activities of phase II drug metabolizing enzymes including UDP-gl.
Application Of Ion-Pair Complexation Reaction For The Spectrophotometric Determination Of Clarithromycin In Pharmaceutical Formulations, Sameer A. M. Abdulrahman
Application Of Ion-Pair Complexation Reaction For The Spectrophotometric Determination Of Clarithromycin In Pharmaceutical Formulations, Sameer A. M. Abdulrahman
The Thai Journal of Pharmaceutical Sciences
Two simple, rapid, sensitive, selective and extraction-free spectrophotometric methods have been developed for the determination of clarithromycin (CLR) both in pure form and in pharmaceutical formulations. The developed methods are based on ion-pair com.
High-Performance Thin-Layer Chromatography Analysis Of (E)-4-(3?,4?-Dimethoxyphenyl)But-3-En-1-Ol (Compound D) In Zingiber Cassumunar Roxb Rhizome Extract: An Application On Genetic Differentiation, Prasan Tangyuenyongwatana, Piyarat Parinyapong Chareonsap, Wandee Gritsanapan
High-Performance Thin-Layer Chromatography Analysis Of (E)-4-(3?,4?-Dimethoxyphenyl)But-3-En-1-Ol (Compound D) In Zingiber Cassumunar Roxb Rhizome Extract: An Application On Genetic Differentiation, Prasan Tangyuenyongwatana, Piyarat Parinyapong Chareonsap, Wandee Gritsanapan
The Thai Journal of Pharmaceutical Sciences
Objectives: This study focused on developing high performance thin-layer chromatography (HPTLC) quantitative analysis method for compound D, a major anti-inflammatory compound in Zingiber cassumunar extract. In addition, the amplified fragment length pol.
Hepatoprotective And Hepatoregenerative Therapeutic Effects Of Polyherbal Medicine Heparmin Tm On Rattus Norvegicus Wistar With Liver Fibrosis, Diana Lyrawati, Amalia Ghassani Muslimah, Dewi Laksmita, Dian Indrawati Santoso, Erlien Lindawati Poernomo, Karina Larasati, Lina Zahrotus Sajidah, Oktavia Rahayu Adianingsih, Rosida Dewi Agusningtyas, Mudjiwijono Handaru Eko, Bogi Pratomo Wibowo
Hepatoprotective And Hepatoregenerative Therapeutic Effects Of Polyherbal Medicine Heparmin Tm On Rattus Norvegicus Wistar With Liver Fibrosis, Diana Lyrawati, Amalia Ghassani Muslimah, Dewi Laksmita, Dian Indrawati Santoso, Erlien Lindawati Poernomo, Karina Larasati, Lina Zahrotus Sajidah, Oktavia Rahayu Adianingsih, Rosida Dewi Agusningtyas, Mudjiwijono Handaru Eko, Bogi Pratomo Wibowo
The Thai Journal of Pharmaceutical Sciences
Chronic injury severely impairs liver regeneration through excess inflammation, scarring and epithelial abnormalities, since injured cells may shift response from pro-regeneration into pro-fibrosis which leads to cirrhosis and total liver failure. An Ind.
Determination Of Potency Of Tetanus Immunoglobulin Products By Commercial Tetanus Anti-Toxoid Test Kits, Wichuda Jariyapan, Kanitta Puwanardnaranuban, Saywarul Jadoonkittnan
Determination Of Potency Of Tetanus Immunoglobulin Products By Commercial Tetanus Anti-Toxoid Test Kits, Wichuda Jariyapan, Kanitta Puwanardnaranuban, Saywarul Jadoonkittnan
The Thai Journal of Pharmaceutical Sciences
Replacement of using experimental animals in scientific research with alternative methods is encouraged, according to the ‘3Rs’ principles (replacement, reduction and refinement). This study presented results for determination of potency of tetanus i...