Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Biology (47)
- Biochemistry, Biophysics, and Structural Biology (18)
- Medicine and Health Sciences (17)
- Animal Sciences (13)
- Biochemistry (12)
-
- Physical Sciences and Mathematics (12)
- Molecular Biology (9)
- Kinesiology (8)
- Ecology and Evolutionary Biology (6)
- Exercise Science (6)
- Engineering (5)
- Nutrition (5)
- Anatomy (4)
- Chemistry (4)
- Environmental Sciences (4)
- Neuroscience and Neurobiology (4)
- Pharmacology, Toxicology and Environmental Health (4)
- Agriculture (3)
- Biodiversity (3)
- Biological Engineering (3)
- Biomedical Engineering and Bioengineering (3)
- Cell and Developmental Biology (3)
- Chemicals and Drugs (3)
- Food Science (3)
- Microbiology (3)
- Other Biochemistry, Biophysics, and Structural Biology (3)
- Other Life Sciences (3)
- Plant Sciences (3)
- Social and Behavioral Sciences (3)
- Institution
- Keyword
-
- Undergraduate research (8)
- Background (2)
- Dewlap (2)
- Group (2)
- Maine (2)
-
- MicroRNA (2)
- Response (2)
- Accuracy (1)
- Acetylation (1)
- Activation (1)
- Acupuncture (1)
- Adverse health effects (1)
- Aerobic (1)
- Agriculture (1)
- Alzheimer's disease (1)
- Amblyomma Maculatum (1)
- Amblyomma americium (1)
- Amyloid plaques (1)
- Angiotensin-Converting Enzymes (1)
- Angular (1)
- Animal Behavior (1)
- Anthropology (1)
- Arginine (1)
- Artificial sweetener (1)
- Awareness (1)
- Behavioral pharmacology (1)
- Bisphenol A (1)
- Bisphenol S (1)
- Bradykinin (1)
- Brain Cancer (1)
- Publication Type
Articles 1 - 30 of 106
Full-Text Articles in Life Sciences
The Effect Of Wee1 On Mitosis In The Spb Mutant, David Leroy
The Effect Of Wee1 On Mitosis In The Spb Mutant, David Leroy
Honors Theses
The speedbump mutant has been identified as an early arrest mutant, becoming apparent as soon as 80% epiboly (8.5 hours of development). This mutant has a mutation in wee1, which is a protein regulating entry into mitosis ensuring the completion of DNA replication before mitosis. The lack of this protein in speedbump allows for early entry into mitosis resulting in damage to the chromosome. Here, we investigate two questions: if mitosis in the speedbump mutant phenotype is more frequent than wild-type phenotype, and, if so, is there a phase in which the mutant phenotype favors. We used phosphorylated histone H3 …
Weight Management Delivered Through An App, May Help Resolve Body Image Dissatisfaction In Women Enrolled In Wic, Alexis Ariel O’Connell
Weight Management Delivered Through An App, May Help Resolve Body Image Dissatisfaction In Women Enrolled In Wic, Alexis Ariel O’Connell
Honors Theses
No abstract provided.
Functional Significance Of Branch Points In Mirtrons, Britton A. Strickland
Functional Significance Of Branch Points In Mirtrons, Britton A. Strickland
Honors Theses
MicroRNAs are a heterogeneous group of small regulatory RNAs generated by many pathways. Mirtrons (miR) are a class of microRNAs produced by splicing, and some mirtrons contain a 3’ tail located downstream from the self-complementary hairpin. During RNA splicing, a loop-like “lariat” intermediate structure is created when the 5’ end of the RNA is attached to an adenine called the branch point. The goal of this project is to uncover the contribution of branch point location to the processing of tailed mirtrons into functional gene regulators. This project approaches this issue from two directions. First, branch points were identified by …
Modern Vet Management Business Plan, Alaina Stanton
Modern Vet Management Business Plan, Alaina Stanton
Honors Theses
No abstract provided.
Expression Of Glycine-Rich Proteins Found In Salivary Glands Of The Lone Star Tick (Amblyomma Americanum) Using A Mammalian Cell Line, Annabelle Clark
Expression Of Glycine-Rich Proteins Found In Salivary Glands Of The Lone Star Tick (Amblyomma Americanum) Using A Mammalian Cell Line, Annabelle Clark
Honors Theses
Ticks play an important ecological role as well as a growing role in human health and veterinary care. Ticks are hosts to a plethora of microbial pathogens that can be transferred during feeding to cause tick-borne diseases in humans and many animals. Ticks may in large part owe the success of the transfer of these pathogens between hosts to their complex saliva. The saliva secreted upon a tick’s attachment to a host serves the following, among other, functions: anti-hemostasis of the blood pool, preventing an inflammatory response at the bite site, and serving as a natural anti-microbial substance. An important …
Protein Residue-Residue Contact Prediction Using Stacked Denoising Autoencoders, Joseph Bailey Luttrell Iv
Protein Residue-Residue Contact Prediction Using Stacked Denoising Autoencoders, Joseph Bailey Luttrell Iv
Honors Theses
Protein residue-residue contact prediction is one of many areas of bioinformatics research that aims to assist researchers in the discovery of structural features of proteins. Predicting the existence of such structural features can provide a starting point for studying the tertiary structures of proteins. This has the potential to be useful in applications such as drug design where tertiary structure predictions may play an important role in approximating the interactions between drugs and their targets without expending the monetary resources necessary for preliminary experimentation. Here, four different methods involving deep learning, support vector machines (SVMs), and direct coupling analysis were …
The Phenology And Compatibility Of Hazelnut (Corylus Avellana) Cultivars In Tennessee, Ben Nigel Heard
The Phenology And Compatibility Of Hazelnut (Corylus Avellana) Cultivars In Tennessee, Ben Nigel Heard
Honors Theses
The European hazelnut (Corylus avellana L.), is an important temperate zone nut tree species for which there is an expanding demand worldwide. Historically, the Eastern filbert blight disease (EFB), caused by the ascomycete fungus Anisogramma anomala, has prevented commercial hazelnut growing in Tennessee. As part of a UTC hazelnut cultivar trial, EFB resistant hazelnut cultivars and numbered selections from Oregon State University and Burnt Ridge Nursery were planted in 2003 at Smith Farm in Ooltewah, TN. Hazelnut trees are wind-pollinated, dichogamous, and self-incompatible, which means they are not self-fertile, their male and female blossoms may open at different times, and …
Investigation Of The Caveolin-Human Follicle Stimulating Hormone Receptor Interaction Through Peptide Treatments, Timothy James Hagan
Investigation Of The Caveolin-Human Follicle Stimulating Hormone Receptor Interaction Through Peptide Treatments, Timothy James Hagan
Honors Theses
The purpose of my research project has been to determine the nature of the binding relationship between caveolin and hFSHR inside sex cells. FSH plays a role in the maturation of these cells, and interfering with the receptor’s interaction with caveolin would prevent cell maturation (down regulating fertility). It is believed the interaction occurs through transmembrane domain IV of the receptor due to its aromatic nature. The treatment of sex cells with synthetic peptides that mimic the hFSHR-caveolin binding sequence should prevent the interaction, shutting down the signaling cascade from hFSHR. This can be tested for by the monitoring of …
Association Of Glucocorticoid Receptor Polymorphisms With Metabolic Characteristics And Bariatric Surgery In Bariatric Patients, Sebastien Gingras
Association Of Glucocorticoid Receptor Polymorphisms With Metabolic Characteristics And Bariatric Surgery In Bariatric Patients, Sebastien Gingras
Honors Theses
Cortisol acts on target tissues through the glucocorticoid receptor (GR). When in high concentration in the blood, it causes an obesity phenotype with hyperglycemia, hyperglyceridemia, hypertension and weight gain, known as Cushings’ Syndrome or Disease (CS/D). Hypersensitivity-causing single-nucleotide polymorphisms (SNPs) of the GR have been shown to lead to a similar phenotype. Because of the symptomatic resemblance between CS/D and Metabolic Syndrome (MS), we and others hypothesized that the MS may be a Cushingoid-like state with absence of hypercortisolemia, but with GR hypersensitivity. Additionally, the link between GR SNPs and the success of bariatric surgery as measured by the percent …
Expressive Writing As A Coping Mechanism For Caregivers Of People With Parkinson's Disease, Sarah Beck
Expressive Writing As A Coping Mechanism For Caregivers Of People With Parkinson's Disease, Sarah Beck
Honors Theses
Caregivers face challenges that take a tremendous toll both mentally and physically, while also having to experience their changing relationship with a loved one who continuously deteriorates. (Ornstein, Gaugler, Devanand, Scarmeas, Zhu, & Stern, 2013). The purpose of my study will be to examine if utilizing expressive writing (EW) can benefit caregivers of loved ones with Parkinson’s disease. I hypothesized that EW would help alleviate caregiver burden, and decrease negative mood and healthier coping means, while caregivers who write within a positive framework will experience the greatest alleviation of burden, better reported mood, and coping means. In this study the …
Organics: Exploring The Parallels Between Botany And Human Anatomy Through Sculpture And Watercolor Painting, Allison Borek
Organics: Exploring The Parallels Between Botany And Human Anatomy Through Sculpture And Watercolor Painting, Allison Borek
Honors Theses
Integrating my two passions of the visual arts and science for my senior thesis, I created a collection of paintings that represent human organs and the parallels between plant biology and animal biology. Genetically, plants are just as complex – if not more – than many animals. They have intricate sensory and regulatory systems highly comparable to humans, and on a cellular level, we share many analogous features. In addition, every single carbon atom that makes up the human body was at one time fixed in a plant during photosynthesis. We also rely on photosynthesis to give us the oxygen …
The Use Of A Feeding Assay To Test The Effects Of Visual Color Contrast On Stimulus Visibility In The Lizard Anolis Sagrei And The Evolution Of Anolis Species In The Dominican Republic, Austin Burnham
Honors Theses
Many animals depend on color signals for communication. It has been hypothesized that signals evolve toward maximum visibility against natural backgrounds. Testing this hypothesis requires a way to assess the influence of signal/background color contrast on signal visibility. Most tests such as these rely on training, which can be very time consuming and difficult for some types of animals. We created a method for testing color contrasts using the lizard Anolis sagrei. We colored dead worms using powdered food coloring and placed them on backgrounds of varying colors and luminance. We presented stimuli in pairs that differed in contrast with …
The United States, China, And Climate Change: An Analysis Of The Us-China Climate Pact And Its Implications For International Climate Negotiations, Joesph Fiorile
Honors Theses
Climate change increasingly is becoming a major issue for the international community. It is contributing to rising global temperatures, rising sea levels, drought, natural disaster intensification, and ecological damage, amongst other things. A scientific consensus has emerged over recent years that implicates greenhouse gases, chief amongst them carbon dioxide, for causing global warming. Climate scientists overwhelmingly agree that the greenhouse gas effect has been caused in large part by the spike of human emissions since the dawn of the Industrial Revolution. To reverse the problem, the density of greenhouse gases in Earth’s atmosphere, especially carbon dioxide, has to be reduced. …
Control System For 3d Printable Robotic Hand, Htoo Wai Htet
Control System For 3d Printable Robotic Hand, Htoo Wai Htet
Honors Theses
Humanoid robotics is a growing area of research due to its potential applications in orthosis and prosthesis for human beings. With the currently available technologies, the most advanced robotic hands used in prosthetics or robotics can cost from $11,000 to $90,000, making it inaccessible to the general population of amputees and robotics hobbyists. Most of the features provided by these expensive technologies are superfluous to many users, creating a great gap in cost and services between users and technology. Using the emerging 3D printing technology, my project is to construct a 3D printed robotic hand that can reproduce as many …
Sugar Consumption Alters Perception Of And Response To Stress In Undergraduate Students: Understanding The "Freshmen Fifteen", Katherine M Keever
Sugar Consumption Alters Perception Of And Response To Stress In Undergraduate Students: Understanding The "Freshmen Fifteen", Katherine M Keever
Honors Theses
Psychological stress is a common part in everyday life that directly affects the body through the nervous system and neuroendocrine hormones. A perceived stressor leads to the activation of the hypothalamic-pituitary-adrenal (HPA) axis, and the synthesis and release of the glucocorticoid hormone cortisol from the adrenal cortex. Studies have linked the release of cortisol during high-stress periods to an increased intake of sugary and fatty foods, consistent with a suspected glucocorticoid-metabolic-brain- negative pathway, with high sugar consumption leading to lower stress and subsequently cortisol levels. In this study, undergraduate students’ diets were supplemented with either a high sugar drink or …
Information Encoded By Dragonfly Visual Neurons Mdt3 And Dit3 In Response To Looming Stimuli, Cara Slugaski
Information Encoded By Dragonfly Visual Neurons Mdt3 And Dit3 In Response To Looming Stimuli, Cara Slugaski
Honors Theses
The Target Selective Descending Neurons (TSDNs) DIT3 and MDT3 in the Aeshnid dragonfly have been shown to respond best to expanding visual stimuli that appear to be approaching, also called looming stimuli. The ratio between the length of the object (L) and the absolute approach velocity (V) completely determines the time course of angular expansion of the object’s image. This study investigated how these neurons responded to the change in expansion of the stimuli, along with which properties of the looming stimuli (target angle, angular expansion rate, or angular acceleration) excite DIT3 and MDT3, respectively. In this experiment, we dissected …
The Effects Of Early Confidence Interval Training On User Efficacy In A P300 Brain-Computer Interface Spelling Task, Adam Starkman
The Effects Of Early Confidence Interval Training On User Efficacy In A P300 Brain-Computer Interface Spelling Task, Adam Starkman
Honors Theses
Brain-computer interface (BCI) technology can provide communication for individuals suffering from degenerative neuromuscular disorders. The present study sought to demonstrate improved BCI performance in healthy individuals using confidence interval training with a P300 BCI spelling program. In this BCI interface, electroencephalographic (EEG) activity was recorded as participants attended to a specific target character within a matrix of flashing letters and numbers presented on a computer screen. The BCI uses the P300 Event Related Potential to select the intended character. In a prior patient case, use of a confidence measure that rejected questionable selections improved that user’s spelling efficiency. The present …
Tubulin Post-Translational Modifications Are Altered By Changes In Actin-Myosin Contractility In Non-Muscle Cells, James Mcgee
Tubulin Post-Translational Modifications Are Altered By Changes In Actin-Myosin Contractility In Non-Muscle Cells, James Mcgee
Honors Theses
All cells regulate their contractility by the interaction of actin and myosin. In non-muscle cells, however, this interaction is regulated by rho, a GTPase, which is the upstream effector for multiple pathways. Cell contractility increases when rho is active, and prior research has shown the depolymerization of microtubules (MTs) activates rho. Microtubules play a role in many cellular functions and it is thought that either associations with MT-associated proteins and/or post-translational modifications to tubulin regulate MT functions. Numerous post-translational modifications (PTMs) to microtubules have been identified, but their roles are not well understood. A possible relationship between changes in cell …
Habitat Light And Signal Color Evolution In 5 Species Of Anoles From The Dominican Republic And The Use Of A Feeding Assay To Test The Effects Of Visual Color Contrast On Stimulus Visibility In The Lizard Anolis Sagrei, Raymond Farmer
Honors Theses
Anolis lizards have excellent color vision and depend on their eyesight to detect visual signals made by other anoles. The dewlap, a colorful and expandable flap of skin, lies beneath the jaw in male anoles and is a primary signaling structure used for territorial and courtship displays. This paper focuses on dewlap color diversity and its evolutionary rudiments. With this in mind, the research team traveled to the Dominican Republic and collected natural habitat light data and dewlap and body color data from the local anoline inhabitants. We hypothesized that light environment would be the main driver behind dewlap color …
Polychlorinated Biphenyl (Pcb) Pollution Of The Hudson River: Social Policy And Health Considerations, Laura Schad
Polychlorinated Biphenyl (Pcb) Pollution Of The Hudson River: Social Policy And Health Considerations, Laura Schad
Honors Theses
The purpose of this paper is to examine pollution in the Hudson River and the role General Electric has had in creating this problem. The focus will be on social issues and problems that have emerged as a result of the environmental damage from pollution. Until recently, there was little research done on the health and environmental justice issues that impact the New York communities where GE’s factories were located. This paper examines the material collected and studies that were done which document Hudson River pollution and the contributions as well as cleanup efforts of General Electric. The overall problems …
Responses Of Dragonfly Visual Neurons Mdt3 And Dit3 To Near-Hit Looming Stimuli, Benjamin Goodman Shapiro
Responses Of Dragonfly Visual Neurons Mdt3 And Dit3 To Near-Hit Looming Stimuli, Benjamin Goodman Shapiro
Honors Theses
Dragonflies are known to have highly sophisticated visual processing systems, allowing precise flight control and incredibly accurate prey capture (Olberg et al., 2000). These processes are mediated by a group of neurons known as Target Selective Descending Neurons, or TSDNs. Of the TSDNs, MDT3 and DIT3 are known to respond to objects expanding into the animal’s field of view, otherwise known as looming objects. Through the use of intracellular electrical recording, we aimed to understand how these two neurons work together to scan the entire visual field, as well as how they respond to objects on a trajectory to miss …
Cannibal Complex: The Western Fascination With Human Flesh Eating, Devin Bittner
Cannibal Complex: The Western Fascination With Human Flesh Eating, Devin Bittner
Honors Theses
For centuries, Western explorers, missionaries, and travelers have been bringing home tales of cannibals, which became the earliest documentation of the practice. Modern anthropology, however, has identified a serious concern with such early “documentation” in light of the rise of the ethnographic tradition: the authors of early reports did not consider the contexts in which the events they observed occurred. This thesis, in the anthropology of knowledge tradition, explores the debate over the Western idea of cannibalism by posing the question: why are we so determined to believe that evidence supporting cannibalism reflects an experiential reality, despite abundant proof of …
Sustainable Agriculture: How France Promotes Sustainability, Jordan Pulling
Sustainable Agriculture: How France Promotes Sustainability, Jordan Pulling
Honors Theses
High consumption lifestyles led to a rapid decline in natural resources. The daily gestures of the people of the world use a quantity massive resource and energy that cannot be replaced. Decision makers of the world are invited to consider what changes will be needed to focus about sustainable and sustainable practices if we want to continue living in the way which we have become accustomed to. The development of renewable energies was a first step towards total sustainable development. Recently, however, we have seen a new way to reduce negative impacts on the rights of the Earth: changes in …
Development Of A [2]-Catenane Synthetic Method And A Student Beliefs Survey For A Hybrid Organometallics Course, Jourdan E. Lakes
Development Of A [2]-Catenane Synthetic Method And A Student Beliefs Survey For A Hybrid Organometallics Course, Jourdan E. Lakes
Honors Theses
In this study, the value-added of a new upper-level chemistry course, CHEM 372-Organometallics, was defined using a Student Beliefs Survey that was answered by students in CHEM 372 and by faculty who teach upper-level chemistry courses at Coastal Carolina University. The laboratory portion of CHEM 372 focused on the synthesis of a [2]-catenane, which is a molecularly interlocked molecule (MIM). The intention was to give the CHEM 372 students a goal to work toward over the course of the semester instead of different, unrelated, experiments each week. Using this style of lab teaching, the students were introduced to graduate school-level …
Learning And Memory In A Drosophila Melanogaster Model Of Alzheimer's Disease, Eric Robles
Learning And Memory In A Drosophila Melanogaster Model Of Alzheimer's Disease, Eric Robles
Honors Theses
Human Alzheimer's disease (AD) is the most prevalent and lethal neurodegenerative disease; it involves the accumulation of neurofibrillary tangles, loss of synapses and neurons in specific areas of the brain, and the presence of extracellular amyloid plaques, particularly Amyloid beta-42 (AP-42). In this study, two Drosophila transgenic fly lines carrying either elav-GAL4 driver or UAS-AP-42 transgene, were crossed to generate AD flies that expressed low levels of human Ap-42. Male AD flies (experimental) and elav-GAL4 flies (as parental control without AP-42) were tested for learning and short-term memory using the courtship suppression assay (Siegal and Hall, 1979). The courtship suppression …
Efficacy Of Benzimidazole Anthelmintics In A Managed Equine Herd In Northeast Texas-- Strategies For An Evidence-Based Targeted Parasite Control Program, Cortney Stewart
Efficacy Of Benzimidazole Anthelmintics In A Managed Equine Herd In Northeast Texas-- Strategies For An Evidence-Based Targeted Parasite Control Program, Cortney Stewart
Honors Theses
No abstract provided.
Towards A Better Understanding Of Antiviral Rnai In Caenorhabditis Elegans: Function Characterization Of Loss Of Antiviral Rnai Alleles 1026a And 1026d, Drake Leonard
Honors Theses
No abstract provided.
An Analysis Of Environmentally-Persistent Free Radical Formation On Surrogate Soil Systems Containing Iron(Iii) And Copper(Ii) And The Potential Remediation Effects Of Laccases, Andrew Paul Mullet
An Analysis Of Environmentally-Persistent Free Radical Formation On Surrogate Soil Systems Containing Iron(Iii) And Copper(Ii) And The Potential Remediation Effects Of Laccases, Andrew Paul Mullet
Honors Theses
No abstract provided.
Pentaerythritol Triacrylate-Co-Trimethylolpropane Nanocomposite Scaffolds As Osteogenic Components For Bone Tissue Engineering, Mollie Marie Smoak
Pentaerythritol Triacrylate-Co-Trimethylolpropane Nanocomposite Scaffolds As Osteogenic Components For Bone Tissue Engineering, Mollie Marie Smoak
Honors Theses
No abstract provided.
The Effects Of Levodopa On The Performance Of Fine Motor Tasks In Individuals With Parkinson's Disease, Collette Maria Tilly
The Effects Of Levodopa On The Performance Of Fine Motor Tasks In Individuals With Parkinson's Disease, Collette Maria Tilly
Honors Theses
No abstract provided.