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Articles 61 - 90 of 1987

Full-Text Articles in Life Sciences

Hawthorn (Crataegus Spp.): Unlocking Its Potential For Health And Environmental Sustainability – A Comprehensive Review, Abdelhak Maghchiche Sep 2025

Hawthorn (Crataegus Spp.): Unlocking Its Potential For Health And Environmental Sustainability – A Comprehensive Review, Abdelhak Maghchiche

Journal of Bioresource Management

Hawthorn (Crataegus spp.), traditionally regarded as an important medicinal plant and frequently cited in the literature, presents significant potential for sustainable development and medical biotechnology. This review looks at several areas of Hawthorn that can be explored in response to current healthcare and environmental sustainability issues. Bioactive compounds from hawthorn, including active compounds primarily comprised of flavonoids, procyanidins, and triterpenoids, are responsible for potent antioxidant, anti-inflammatory, cardio-protective, and antimicrobial activities, potentially providing a source of potent therapeutic alternatives. Moreover, hawthorn has a well-documented record as a source of cardiovascular benefits to address arterial hypertension, congestive heart failure, and arrhythmias. In …

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Diversity Of Butterflies (Lepidoptera) In Kanju, District Swat, Khyber Pakhtunkhwa, Pakistan, Said Miraj Ud Din, Khushbakht Asad, Hamid Ur Rahman, Attiya Iqbal Sep 2025

Diversity Of Butterflies (Lepidoptera) In Kanju, District Swat, Khyber Pakhtunkhwa, Pakistan, Said Miraj Ud Din, Khushbakht Asad, Hamid Ur Rahman, Attiya Iqbal

Journal of Bioresource Management

Butterflies are one of the most beautiful creatures on earth. They belong to the phylum Arthropoda, class Insecta, and order Lepidoptera. Butterflies play an important role in the ecosystem, contributing significantly to pollen transfer. They play an important role in pollination, and their foraging behavior enhances the genetic diversity. Additionally, they also play an important role in the food chain and serve as prey for birds, reptiles, and other insectivore organisms. The current study was conducted to find out the diversity and distribution of butterflies in Kanju district Swat, Khyber Pakhtunkhwa, Pakistan. A total 203 specimens were collected from August …

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Seroprevalence, Risk Factors, And Diagnostic Accuracy Of Brucellosis In Upper Dir District, Khyber Pakhtunkhwa, Pakistan, Sidra Sanam, Kamran Khan Sep 2025

Seroprevalence, Risk Factors, And Diagnostic Accuracy Of Brucellosis In Upper Dir District, Khyber Pakhtunkhwa, Pakistan, Sidra Sanam, Kamran Khan

Journal of Bioresource Management

Brucellosis is a zoonotic disease caused by the gram-negative, intracellular bacterium Brucella. Although it is endemic in Pakistan, comprehensive data on its prevalence, risk factors, and diagnostic accuracy remain limited. Therefore, this study aimed to assess these parameters in local communities of District Dir Upper, Khyber Pakhtunkhwa, Pakistan. A total of 345 individuals suspected of brucellosis were investigated. Blood samples and structured questionnaires were collected to determine prevalence and identify associated risk factors. Additionally, 50 culture-confirmed positive cases and 50 negative controls were used to evaluate the diagnostic performance of Enzyme-Linked Immunosorbent Assay (ELISA) and Serum Plate Agglutination Test …

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The Phenology Of Nine Native Tree Species In Gera Moist Afromontane Forest, Southwest Ethiopia, Dereje Egeta, Giche Yadesa, Abeje Eshete, Hailu Belay, Urge Charu, Tensay Teshome Sep 2025

The Phenology Of Nine Native Tree Species In Gera Moist Afromontane Forest, Southwest Ethiopia, Dereje Egeta, Giche Yadesa, Abeje Eshete, Hailu Belay, Urge Charu, Tensay Teshome

Journal of Bioresource Management

Phenology is the study of the time series of biological phenomena of plants, such as flowering, fruiting, and leaflessness, related to seasonal change. Ethiopia is rich in vascular plant species. However, the tree phenology of selected species has been less studied. Therefore, the study aimed to document the phenology of nine native tree species in the Gera moist Afromontane forest in southwest Ethiopia. Forty-five mature trees (five of each species) were selected and numbered according to their species. The intensity of flowering and fruiting was assigned to four different classes. PAST software (version 4.03) and Microsoft Excel (version 2016) mapped …

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Trophic Niche Overlap Between Native And Alien Fish Species: A Challenge For The Aquatic Ecosystems, Rana Manzoor Ahmad, Abdul Majid Khan, Mariya Basharat, Muhammad Rizwan, Neelam Shahzadi, Muhammad Imran Sep 2025

Trophic Niche Overlap Between Native And Alien Fish Species: A Challenge For The Aquatic Ecosystems, Rana Manzoor Ahmad, Abdul Majid Khan, Mariya Basharat, Muhammad Rizwan, Neelam Shahzadi, Muhammad Imran

Journal of Bioresource Management

The different physiological and biological challenges are introduced not only on land but also in aquatic ecosystems due to increasing climatic changes and human needs. One of these challenges is the introduction of invasive alien species to the native freshwater ichthyofauna. These species not only disturb the ecological balance of the native water bodies but can also be a vector for parasitic diseases. The current study is designed to disclose the trophic niche overlap among exotic (Cyprinus carpio and Oreochromis mozambicus) and indigenous fish species (Labeo calbasu and Cirrhinus mrigala) from Head Baloki (Ravi River), Punjab, …

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Knowledge Of Hiv Transmission And Prevention Among University Students In Pakistan: A Cross-Sectional Study, Muhammad Saleem, Sajid Masood, Shahid Hussain Jun 2025

Knowledge Of Hiv Transmission And Prevention Among University Students In Pakistan: A Cross-Sectional Study, Muhammad Saleem, Sajid Masood, Shahid Hussain

Journal of Bioresource Management

HIV/AIDS remains a significant public health problem internationally, with young adults being especially at risk because of behavioral and knowledge deficits. In Pakistan, cultural inhibitions and suboptimal health education are the main reasons for limited awareness, particularly among university students. This study had the objectives of determining the knowledge level about HIV transmission and prevention among undergraduate students in Kohsar University Murree (KUM) and to investigate correlations with salient demographic variables. A cross-sectional survey was carried out among 510 students aged 18-27 years through a pre-validated, standardized questionnaire with 12 knowledge-based items. Descriptive statistics and Chi-square tests were utilized to …

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Beyond Silence: A Review- Exploring Sensory Intelligence, Perception And Adaptive Behaviour In Plants, Taranisen Panda, Nirlipta Mishra, Shaik Rahimuddin, Bikram Pradhan, Rajballav Mohanty Jun 2025

Beyond Silence: A Review- Exploring Sensory Intelligence, Perception And Adaptive Behaviour In Plants, Taranisen Panda, Nirlipta Mishra, Shaik Rahimuddin, Bikram Pradhan, Rajballav Mohanty

Journal of Bioresource Management

Plants, traditionally viewed as passive organisms, exhibit sensory and adaptive abilities that challenge conventional notions of plant biology. All organisms evolve ways to sense and interact with their surroundings, and plants, although lacking eyes, ears, or brains, perceive the world in sophisticated ways. Despite lacking a nervous system and other features typically associated with animals, plants can see, smell, hear, feel, learn, remember, and act similarly to animals. This review examines how plants perceive and respond to their environment using mechanisms analogous to vision, hearing, smell, taste, and touch, adjusting their morphology, physiology, and phenotype accordingly. Drawing from plant physiology, …

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Soil Degradation Of Solvent-Cast Pha Films Produced By Bacillus Tequilensis Pwf Using Waste Polyethylene Terephthalate (Pet), Rafeya Sohail, Rida Batool, Nazia Jamil Jun 2025

Soil Degradation Of Solvent-Cast Pha Films Produced By Bacillus Tequilensis Pwf Using Waste Polyethylene Terephthalate (Pet), Rafeya Sohail, Rida Batool, Nazia Jamil

Journal of Bioresource Management

Polyhydroxyalkanoate (PHA) aliphatic polymers however efficiently biodegradable, still pose a contradiction with the principles of green chemistry. Use of bacterial strains capable of degrading synthetic plastics for the production of biopolymers i.e., PHAs may aid in reduction of plastic pollution. Bacterial strains PWA; Bacillus subtilis (MH142143), PWF; Bacillus tequilensis (MH142145), and PWG; Bacillus safensis (MH142146) were grown on waste shredded PET and PET flakes. Highest bioconversion of PET to PHA was observed using PET flakes. Strain PWF produced 40.47 % (0.815 g/L) and 31.80 % (0.626 g/L) PHA using PET flakes and shredded PET at 48 h, respectively. Whereas highest …

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Dietary Organic Selenium Supplementation Improved Some Gross Morphological Parameters And Biochemical Characteristics Of Testes In Young Male Kids, Nadia Rahim, Moolchand Malhi, Asma Babar, Muhammad Awais Soomro, Shazia Rahim Jun 2025

Dietary Organic Selenium Supplementation Improved Some Gross Morphological Parameters And Biochemical Characteristics Of Testes In Young Male Kids, Nadia Rahim, Moolchand Malhi, Asma Babar, Muhammad Awais Soomro, Shazia Rahim

Journal of Bioresource Management

Selenium (Se) plays a vital role in improving reproductive health in ruminants. This study evaluated the impact of Se supplementation on testicular health in young male goats. Twenty goats (2–3 months old, 8.5–10 kg) were randomly assigned to two groups: Control (C, n=10) receiving a basal diet (0.037 mg Se/kg) and Se-Yeast (SY, n=10) supplemented with 0.3 mg Se/kg diet. The trial lasted eight weeks. Results showed that testis weight was significantly higher in the SY group (26.8 ± 2.5 g) compared to C (22.4 ± 2.1 g, p < 0.05). Testis length, width, and circumference also increased significantly in SY goats (4.5 ± 0.3 cm, 2.9 ± 0.2 cm, and 7.4 ± 0.4 cm, respectively) compared to control (3.9 ± 0.4 cm, 2.5 ± 0.3 cm, and 6.7 ± 0.5 cm; p < 0.05). Serum cholesterol was higher in SY (135.27 ± 2.34 mg/dl) than in C (121.15 ± 8.74 mg/dl, p = 0.02), while triglycerides were lower (95.99 ± 1.37 vs. 114.38 ± 1.84 mg/dl, p = 0.0003). HDL increased (51.97 ± 2.10 vs. 45.02 ± 1.32 mg/dl, p = 0.03), and LDL decreased (54.23 ± 1.81 vs. 61.27 ± 1.56 mg/dl, p = 0.02) in SY group. Total serum protein rose significantly (8.14 ± 0.79 vs. 5.25 ± 0.06 mg/dl, p = 0.03), as did testosterone levels (1.95 ± 0.08 vs. 1.43 ± 0.06 ng/ml, p = 0.002). In conclusion, selenium supplementation significantly improved testicular morphology, lipid profile, protein levels, and testosterone, indicating enhanced reproductive health in goats.

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Emergence Of Caenocoris Neri (Germar, 1847) On Fig Trees In The Oases Of Southeastern Algeria, Nacima Diab, Tesnim Deghiche, Khalila Bengouga, Vasily Vladimirovich Verkhoturov Jun 2025

Emergence Of Caenocoris Neri (Germar, 1847) On Fig Trees In The Oases Of Southeastern Algeria, Nacima Diab, Tesnim Deghiche, Khalila Bengouga, Vasily Vladimirovich Verkhoturov

Journal of Bioresource Management

The article considers materials related to current areas of fundamental research in the field of agricultural entomology in Algeria. The most important issues of agricultural entomology in Algeria include identifying patterns of general trends in the dynamics of geographic ranges of phyto-entomophagous under the influence of climatic and anthropogenic factors, as well as studying the adaptation of insects to new habitats and food supply. In a notable discovery during insect sampling conducted in the oasis ecosystem during the summer of 2019, researchers recorded and identified individuals of the species Caenocoris nerii (Germar, 1847) for the first time. These insects were …

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The Northern Lapwing (Vanellus Vanellus Linnaeus, 1758), A New Species In The List Of Charadriidae In The Western Steppes Of Algeria, Youcefi Ahmed Toufik, Litim Kouider Jun 2025

The Northern Lapwing (Vanellus Vanellus Linnaeus, 1758), A New Species In The List Of Charadriidae In The Western Steppes Of Algeria, Youcefi Ahmed Toufik, Litim Kouider

Journal of Bioresource Management

This manuscript aims to authenticate the presence of a species of wild bird: Northern Lapwing (Vanellus vanellus Linnaeus, 1758), which represents a first in the western steppes areas of Algeria. The sighting was recorded in the treated wastewater treatment plant west of the municipality of Mécheria. The phonological status of this species can be classified as a passing visitor. This presence can be justified by the food rules of the Northern Lapwing (Vanellus vanellus Linnaeus, 1758) which is insectivorous and finds in this area prey on which it feeds.

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Utilization Of Watermelon Rind Waste Powder For Developing Bakery Products, Babar Khan, Asadullah Marri, Nida Shaikh, Asif Irshad Jun 2025

Utilization Of Watermelon Rind Waste Powder For Developing Bakery Products, Babar Khan, Asadullah Marri, Nida Shaikh, Asif Irshad

Journal of Bioresource Management

Watermelon rind waste powder (WRWP) is a rich source of dietary fiber and bioactive compounds; hence it could be used to develop functional foods such as bakery products. The present study aimed to utilize WRWP in bakery products development. The treatments included: T1 = Cake without WRWP, T2 = Cake with 10 % WRWP, T3= Cake with 20 % WRWP, T4= Biscuit without WRWP, T5 = Biscuit with 10 % WRWP, T6 = Biscuit with 20 % WRWP. The physicochemical and nutritional properties of watermelon rind waste powder were also determined. The …

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Psychological Influence Of Acne Vulgaris Among Female Students Of University Of Poonch Rawalakot Azad Jammu And Kashmir, Pakistan, Faryal Hanif, Ahmed Hussain, Ehsan Ali, Muhammad Rasheed Mar 2025

Psychological Influence Of Acne Vulgaris Among Female Students Of University Of Poonch Rawalakot Azad Jammu And Kashmir, Pakistan, Faryal Hanif, Ahmed Hussain, Ehsan Ali, Muhammad Rasheed

Journal of Bioresource Management

This study aimed to assess the prevalence of acne vulgaris among female students at the University of Poonch, Rawalakot, and to evaluate its impact on their quality of life using the Dermatology Life Quality Index (DLQI). A cross-sectional survey was conducted from July to August 2022, involving a total of 2000 female students. Out of these, 400 individuals were clinically diagnosed with acne vulgaris, indicating a prevalence rate of 20 %. The participants completed the DLQI questionnaire, which evaluates the psychological and social effects of dermatological conditions. The data obtained were analyzed to assess the influence of acne on various …

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Review On Biological Management Of Bactrocera Zonata Through Pathogenic Activity Of Beauveria Bassiana, Sana Ullah, Hafiz Muhammad Sajid Ali, Syed Husnain Kumail Naqvi, Muhammad Ziaullah, Farhan Ali, Sana Sarfaraz, Mamoona Kanwal Mar 2025

Review On Biological Management Of Bactrocera Zonata Through Pathogenic Activity Of Beauveria Bassiana, Sana Ullah, Hafiz Muhammad Sajid Ali, Syed Husnain Kumail Naqvi, Muhammad Ziaullah, Farhan Ali, Sana Sarfaraz, Mamoona Kanwal

Journal of Bioresource Management

Bactrocera zonata is the destructive pest of peach, mango, and banana by causing significant economic losses. It reduces fruit quality which directly causes decline in export of these economical fruits. Many management strategies were carried to suppress the population of this invasive pest. The use of chemical insecticides in the orchard for control of B. zonata is restricted because insecticides cause several complications in fruit health and makes fruits unfit for human consumption. Due these drawbacks of chemical control, Biological control strategies are preferred for better management of B. zonata. Entomopathogenic fungi are potential bio-control agent against many insect …

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Nitrogen Application Enhances The Radiation Use Efficiency And Quality Of Cotton (Gossipum Hirsutum L.) Under Divergent Agro-Ecological Conditions Of Pakistan, Amjed Ali, Safdar Hussain, Wajid Nazeer, Muhammad Sarwar, Masood Qadir, Mubashar Nadeem, Javeria Sherani Mar 2025

Nitrogen Application Enhances The Radiation Use Efficiency And Quality Of Cotton (Gossipum Hirsutum L.) Under Divergent Agro-Ecological Conditions Of Pakistan, Amjed Ali, Safdar Hussain, Wajid Nazeer, Muhammad Sarwar, Masood Qadir, Mubashar Nadeem, Javeria Sherani

Journal of Bioresource Management

Cotton being a cash crop plays a pivotal role in the economy of Pakistan. Climate change has a pronounced impact on radiation use efficiency and quality of cotton fiber. To find out how nitrogen affected the radiation use efficiency and fiber quality of cotton cultivars in Punjab, a field study using a split-plot design was carried out. The study under representation was conducted in three different locations over the course of two years (2016 and 2017): Adaptive Research Farm in Dera Ghazi Khan, The Regional Agriculture Research Institute, Bahawalpur and The College of Agriculture, University of Sargodha. Three cotton cultivars …

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Impact Of Climate Change On The Diversity And Abundance Of Wintering Birds At A Northern African Wetland - Case Study Of Oglat Eddaira Wetland (Naama, Western Algeria), Ahmed Toufik Youcefi, Gouacem Ali, Litim Kouider, Haddi Leila, Messaoui Fatima Mar 2025

Impact Of Climate Change On The Diversity And Abundance Of Wintering Birds At A Northern African Wetland - Case Study Of Oglat Eddaira Wetland (Naama, Western Algeria), Ahmed Toufik Youcefi, Gouacem Ali, Litim Kouider, Haddi Leila, Messaoui Fatima

Journal of Bioresource Management

The Mediterranean regions have been classified as the areas of the world most susceptible to the effects of environmental change. These regions are sensitive to drought and rising temperatures and with heightened aridity in the next several years. The purpose of this paper is to study the effects of climate change on the diversity and abundance of wintering birds in the Oglat Eddaira wetland located in western Algeria and classified in the Ramsar list. This study is based on the comparison between some indices of biodiversity: species richness, abundance, Shannon-Weiner and Simpson Index, during the period 2015 to 2024 and …

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Aerial Phytomass And Carbon Sequestrated By The Kitshanga Forest Massif In The Wamba Valley In Dr-Congo, Mayanu Pemba, Ntalakwa Makolo, Kidikwadi Tango, Lubini Ayingweu Mar 2025

Aerial Phytomass And Carbon Sequestrated By The Kitshanga Forest Massif In The Wamba Valley In Dr-Congo, Mayanu Pemba, Ntalakwa Makolo, Kidikwadi Tango, Lubini Ayingweu

Journal of Bioresource Management

Aerial phytomass and carbon sequestrated by the Kitshanga forest massif in the Wamba valley in DR-Congo. The general objective was to evaluate the aerial phytomass and the carbon contained in the ligneous tissues of the trees. Specifically, the research aims to: (i) inventory all individuals in the Kitshanga gallery forest; (ii) identify the species in the study area; (iii) determine the floristic composition and density of the stand studied and (iv) evaluate the phytomass and the carbon sequestered by this vegetation. Inventory devices full on 1 hectare subdivided by 400 m² to obtain 25 plots which constitute the size of …

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Avifauna Of Kheri Morat National Park: Role Of Agricultural Habitat In Maintaining The Diversity Of Birds In The Presence Of Threats In Adjacent Forest Habitat, Syed Ali Hasnain Mosvi, Saeed Azam, Abdullah Ibrahim, Saleha Abbasi, Nadeem Munawar, Muhammad Arslan Asadi Mar 2025

Avifauna Of Kheri Morat National Park: Role Of Agricultural Habitat In Maintaining The Diversity Of Birds In The Presence Of Threats In Adjacent Forest Habitat, Syed Ali Hasnain Mosvi, Saeed Azam, Abdullah Ibrahim, Saleha Abbasi, Nadeem Munawar, Muhammad Arslan Asadi

Journal of Bioresource Management

Increasing land use for agricultural practices is commonly perceived as a threat to the avian diversity. However, a number of avian species depend on these croplands for food, water, and shelter. The present study was conducted in Khairi National Park, Pakistan, for the discourse of awareness gaps about the avifaunal diversity of the protected area and to compare the bird’s diversity in the agriculture fields and native forests. For the current study, the habitat was divided into two habitat categories, i.e., forest and croplands. The sampling was executed between February 2014 and February 2017. Stratified random sampling was used to …

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Study On Predisposing Factors And Control Measures Against Cryptosporidiosis In Buffalo Calves At Cattle Colony Hyderabad, Sindh, Pakistan, Ali Ul Murtaza, Abdul Latif Bhutto, Jam Kashif Zaman, Mansoor Tariq, Amjad Hussain Mirani, Riaz Ahmed Laghari, Pervez Ahmed Khoso, Muhammad Mohsen Rahimoon, Abdul Saboor, Fayaz Hussain Mar 2025

Study On Predisposing Factors And Control Measures Against Cryptosporidiosis In Buffalo Calves At Cattle Colony Hyderabad, Sindh, Pakistan, Ali Ul Murtaza, Abdul Latif Bhutto, Jam Kashif Zaman, Mansoor Tariq, Amjad Hussain Mirani, Riaz Ahmed Laghari, Pervez Ahmed Khoso, Muhammad Mohsen Rahimoon, Abdul Saboor, Fayaz Hussain

Journal of Bioresource Management

The current study looked at the variables affecting the frequency of Cryptosporidium Parvum in buffalo calves at the Hyderabad Cattle Colony. From calves, 100 fecal samples were taken in total, preserved, and analyzed using direct smear and Ziehl-Neelsen staining methods. 74 percent of the samples tested positive for Cryptosporidium Parvum. Disease rates were higher in Nili Ravi calves (86 %) compared to Kundhi calves (62 %), with a statistically significant difference (p

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Review On Treatment Outcome Of Patient With Acute Bacterial Meningitis In Pediatrics, Uswa Insaf, Faiza Waseem, Nadia Iqbal, Tehseen Riaz, Irfan Bashir, Waqas Akram Mar 2025

Review On Treatment Outcome Of Patient With Acute Bacterial Meningitis In Pediatrics, Uswa Insaf, Faiza Waseem, Nadia Iqbal, Tehseen Riaz, Irfan Bashir, Waqas Akram

Journal of Bioresource Management

Antibiotic treatment improves outcomes of treatment, but extensively available antibiotics efficiency is vulnerable by globally appearance of development of multidrug-resistant bacteria. An infectious etiology arises, such as fungi, bacteria, viruses, mycobacteria, or parasites, or be related with cancer, autoimmunity, or medications reaction. The causative organism was recognized by most patients treated with antibiotics, culture of the CSF and blood, by countercurrent immune-electrophoresis of fluids. Neisseria meningitidis, Hemophilus influenzae b and Streptococcus pneumoniae are the commonest causes of bacterial meningitis. Bacterial meningitis has adequately extreme in the pediatrics people of developing countries. Many people with bacterial meningitis don't have any …

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Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Thursday, March 13, 2025, Wright State University Mar 2025

Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Thursday, March 13, 2025, Wright State University

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Abstract Books

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Celebration of Student Research, Scholarship & Creative Activities on March 13, 2025.

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Generative Ai (Gan & Vae) In Motion Sickness Research, Harigovind Harikumar, Tomojit Ghosh Jan 2025

Generative Ai (Gan & Vae) In Motion Sickness Research, Harigovind Harikumar, Tomojit Ghosh

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

No abstract provided.

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A Systematic Study Of Freezing Behavior In Earthworms In Response To Auditory And Vibratory Stimuli, Navjot Singh, A. Burton, Dragana Ivkovich Claflin Jan 2025

A Systematic Study Of Freezing Behavior In Earthworms In Response To Auditory And Vibratory Stimuli, Navjot Singh, A. Burton, Dragana Ivkovich Claflin

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

While earthworms have largely been studied for their role in eliminating toxic metals from soil, less is known about their behavior overall. Previous work from our lab found that a predator-like auditory stimulus (grunting) reliably induced fear-related freezing behavior (Worthen et al., 2024). The present studies further explore earthworm behaviors in response to audio-vibratory stimuli. In Experiment 1, we manipulated amplitude levels and speaker location to examine the parameters needed to reliably induce a freezing fear response to the grunting sound. It was hypothesized that when the speaker was touching the apparatus and producing an added mechanical vibration, there would …

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The Responses Of Insect Herbivores And Local Food Webs To Invasive Shrubs, Logan W. Huber Jan 2025

The Responses Of Insect Herbivores And Local Food Webs To Invasive Shrubs, Logan W. Huber

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Invasive species cause widespread ecological disruption and economic loss. Invasive plants in particular have the potential to reshape forest food webs from the bottom up. However, the extent to which herbivores colonize and assimilate invasive plants into their diets remains unclear. To address this, I surveyed caterpillar abundance, richness, and herbivory on two invasive shrubs, Lonicera maackii and Elaeagnus umbellata, across regions differing in infestation history. Lonicera maackii supported lower overall caterpillar abundance and richness but hosted a more diverse and abundant caterpillar community in the heavily infested region. E. umbellata supported robust caterpillar communities and experienced herbivory levels comparable …

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Evidence That Ultraviolet B Radiation Generates Systemic Responses Via Microvesicle Particle, Niharika Annapureddy Jan 2025

Evidence That Ultraviolet B Radiation Generates Systemic Responses Via Microvesicle Particle, Niharika Annapureddy

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Ultraviolet B (UVB) radiation, ranging from 280–315 nm, has been identified as carcinogenic since 1928 and is known to cause skin cancer. Additionally, UVB exposure triggers inflammatory responses, systemic effects, and organ damage. Recent research has discovered that these adverse outcomes are facilitated by the release of microvesicle particles (MVP) via the inflammatory lipid mediator, Platelet-activating Factor (PAF). We have previously demonstrated that sunburn causes skin keratinocytes to release high levels of MVP by activating the PAF receptor (PAFR). These studies were designed to test if these microvesicles enter the bloodstream and travel to various organs, especially the gut, increasing …

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Synthetic Nucleoside Labels For Studying Cell-Free Dna, Dibya Guragai Jan 2025

Synthetic Nucleoside Labels For Studying Cell-Free Dna, Dibya Guragai

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Cell-free DNA (cfDNA) can arise from dying cells or be actively secreted by living cells, and is found either unbound, within extracellular vesicles, or in other macromolecular complexes. cfDNA plays roles in intercellular communication and immune responses and is clinically used for diagnostics through PCR and DNA sequencing. Interestingly, our lab has detected lesions in cfDNA after treatment with DNA-damaging agents including UVB and cisplatin. These findings prompted further investigation into which DNA lesions and labels can be found in the cell-free space. Importantly, we sought a mechanism of labeling DNA with a synthetic nucleoside to enable robust tracing using …

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Systemic Effects Of Varying Degrees Of Thermal Burn Injuries In Young Mice: Role Of Microvesicle Particles And Platelet-Activating Factor, Prince Wilfred Jan 2025

Systemic Effects Of Varying Degrees Of Thermal Burn Injuries In Young Mice: Role Of Microvesicle Particles And Platelet-Activating Factor, Prince Wilfred

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Thermal burn injuries (TBI) result in local and systemic effects, particularly when a large body surface area is exposed to TBI. This study investigates the systemic effects of varying degrees of TBI in the murine model, focusing on the role of microvesicle particles (MVP) and Platelet-activating Factor (PAF) in mediating bacterial translocation and systemic inflammation. Utilizing the murine model, we analyzed MVP levels in the skin and blood, bacterial translocation in the gut, and the expression of pro-inflammatory mediators in the major organs at the 2-hour post-burn time point. Our studies revealed that after the two hours’ time point TBI …

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Effects Of Canagliflozin And Pioglitazone On Cardiac Ras And Sirt1 In Db/Db Diabetic Mice, Purab Sanjay Sood Jan 2025

Effects Of Canagliflozin And Pioglitazone On Cardiac Ras And Sirt1 In Db/Db Diabetic Mice, Purab Sanjay Sood

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Type 2 diabetes significantly increases the risk of diabetic cardiomyopathy (DCM) and nephropathy, largely due to hyperglycemia-induced activation of the renin-angiotensin system (RAS) and elevated levels of angiotensin II (Ang II). Angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) mitigate the deleterious effects of Ang II by generating Ang-(1-7), a cardioprotective vasodilator. ACE2 is essential for cardiac function, while its deficiency exacerbates dysfunction. Furthermore, the silent information regulator 1 (SIRTl) promotes ACE2 expression and contributes to cardiovascular protection. Despite the availability of several classes of antidiabetic medications, some cardiovascular complications of diabetes persist, and intensive glycemic control does not always …

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Examining The Biotic And Abiotic Degradation Of Simple Phenols, Madeline Gruenberg Jan 2025

Examining The Biotic And Abiotic Degradation Of Simple Phenols, Madeline Gruenberg

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Plant secondary metabolites are a diverse class of compounds that encompass small phenols to large polymeric structures such as tannins. Smaller compounds such as phenolic acids can serve as substrates for soil microbes and enzymes. We monitored the degradation of three small phenols pyrogallol, gallic acid, and benzoic acid in biotic and abiotic conditions. They were chosen to observe the impacts of specific functional groups on both degradation processes and act as model compounds to mimic larger tannin reactivity. Both abiotic and biotic degradation of pyrogallol resulted in the formation of a stable quinone, while abiotic degradation of gallic acid …

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The Circadian Modulating Drug Sr8278 Slows Cell Proliferation Independent Of Rev-Erbs, Ushaswini Atluri Jan 2025

The Circadian Modulating Drug Sr8278 Slows Cell Proliferation Independent Of Rev-Erbs, Ushaswini Atluri

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The small molecule compound SR8278 was initially identified as an antagonist of the REV-ERB proteins, which play an important role in regulating circadian rhythms. Furthermore, the use of SR8278 in preclinical models has been demonstrated to ameliorate a variety of different pathologies. Using RNA-seq analysis of HaCaT keratinocytes treated with SR8278, our laboratory found that SR8278 induces a down regulation of genes involved in the G1/S phase transition of the cell cycle and an up regulation of genes involved in cholesterol biosynthesis. RT-qPCR and western blot analyses confirmed that SR8278 treatment led to lower expression of several factors involved in …

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