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Articles 31 - 60 of 63
Full-Text Articles in Life Sciences
Geometric Build-Up Solutions For Protein Determination Via Distance Geometry, Robert Tucker Davis
Geometric Build-Up Solutions For Protein Determination Via Distance Geometry, Robert Tucker Davis
Masters Theses & Specialist Projects
Proteins carry out an almost innumerable amount of biological processes that are absolutely necessary to life and as a result proteins and their structures are very often the objects of study in research. As such, this thesis will begin with a description of protein function and structure, followed by brief discussions of the two major experimental structure determination methods. Another problem that often arises in molecular modeling is referred to as the Molecular Distance Geometry Problem (MDGP). This problem seeks to find coordinates for the atoms of a protein or molecule when given only a set of pair-wise distances between …
Role Of Cd4+Cd25+ Regulatory T Lymphocytes In Experimental Toxoplasmosis, Sanjay Varikuti
Role Of Cd4+Cd25+ Regulatory T Lymphocytes In Experimental Toxoplasmosis, Sanjay Varikuti
Masters Theses & Specialist Projects
Toxoplasmosis is an important cause of congenital disease, and it is one of the most common opportunistic infections in patients with acquired immunodeficiency syndrome. The need for a reliable experimental model of this infection is crucial not only for achieving a better understanding of the patho-physiology of the disease, but also for developing better methods for evaluating new therapeutic regimens. The purpose of the present study was to investigate the role of CD4+CD25+ T regulatory lymphocytes in mice infected with Toxoplasma gondii. T regulatory (Treg) cells have been shown to play an important role in our immune system in …
Wyatt, Albert F., 1861-1943 (Sc 1959), Manuscripts & Folklife Archives
Wyatt, Albert F., 1861-1943 (Sc 1959), Manuscripts & Folklife Archives
MSS Finding Aids
Finding aid only for Manuscripts Small Collection 1959. Letter, 14 April 1908, from A. F. Wyatt, Mt. Sterling, Kentucky to H. R. Cowles, Statesville, North Carolina regarding the availability of horses for sale.
Assessing Organic Matter Breakdown And Associated Macroinvertebrate Community Structure In Headwater Streams: Effects Of Hydrologic Gradients And Upland Timber Harvesting, Miller Scott Jarrell
Assessing Organic Matter Breakdown And Associated Macroinvertebrate Community Structure In Headwater Streams: Effects Of Hydrologic Gradients And Upland Timber Harvesting, Miller Scott Jarrell
Masters Theses & Specialist Projects
I examined the effects of hydrologic gradients and upland timber harvesting with different streamside management zone widths on yellow-poplar (Liriodendron tulipifera) processing and the associated macroinvertebrate community structure in the Cumberland Plateau ecophysic region, U.S.A. Prior to upland timber harvesting, 5.0 ± 0.1 g yellow-poplar leaf packs were constructed, zip-tied to gutter nails, and placed into 7 perennial and 6 temporary stream reaches with similar physiochemical and geomorphic characteristics. From December 2007 to May 2008, 3–5 leaf packs were collected per reach monthly. I found significant differences in the functional feeding group composition. Temporary reaches contained higher shredder, gathering-collector, predator, …
The Effect Of Endothelin-1 On The Expression Of Cdk Inhibitors P21 & P27 In Bovine Corneal Endothelial Cells, Lakshmi Reddy Bollu
The Effect Of Endothelin-1 On The Expression Of Cdk Inhibitors P21 & P27 In Bovine Corneal Endothelial Cells, Lakshmi Reddy Bollu
Masters Theses & Specialist Projects
Mammalian corneal endothelial cells are considered to be non-proliferative due to the arrest of cells at the G1 phase of the cell cycle. The purpose of this study was to determine whether the down regulation of cyclin dependant kinase inhibitors (p21cip1 and p27kip1) levels by Endothelin-1 (ET-1), would overcome the G1 phase arrest and promote cell cycle progression and proliferation in cultured BCECs (Bovine corneal endothelial cells). BCECs were isolated from bovine corneas and cultured in DMEM supplemented with 10% serum. 5-Bromo 2-deoxy Uridine (BrdU) incorporation was determined in serum starved cultures in 24-well plates as a measure of cell …
Confidence Intervals For The Ratio Of Two Exponential Means With Applications To Quality Control, James Albert Polcer,Iii
Confidence Intervals For The Ratio Of Two Exponential Means With Applications To Quality Control, James Albert Polcer,Iii
Student Research Conference Select Presentations
We considered the problem of statistical quality control based on the ratio of two population means. We restrict the discussion for two exponential rates, which are commonly used for modeling failure times of components, machines, or systems. Closed form expressions via the moment generation function (MGF) technique will be presented, and numerical examples will be shown using engineering data sets.
Nuttle, Jason And Victoria Conaster (Fa 426), Manuscripts & Folklife Archives
Nuttle, Jason And Victoria Conaster (Fa 426), Manuscripts & Folklife Archives
FA Finding Aids
Finding aid only for Folklife Archives Project 426. Interview with Marlene Harrison conducted by Jason Nuttle and Victoria Conaster for a Western Kentucky University folk studies class.
The Effect Of Breeding Herd Parity Structure On Genetic Improvement Of The Sow Herd, Caitlyn E. Abell
The Effect Of Breeding Herd Parity Structure On Genetic Improvement Of The Sow Herd, Caitlyn E. Abell
Mahurin Honors College Capstone Experience/Thesis Projects
This study focuses on the value of the genetic lag associated with maintaining sows for additional parities in a commercial swine herd. Three traits were included in this study: number born alive (NBA), 21 day litter weight (W21), and days to market (D250). The economic values assigned to these traits were $22.00/pig, $0.70/lb., and $0.17/day, respectively. The genetic improvement per generation made for each trait was assumed to be 0.3 pigs, 3.0 lbs., and 3.0 days, respectively. It was estimated that the value of the genetic lag associated with retaining a sow to P3, P5, and P7 was $24.80, $46.89, …
Kentucky Warbler (Vol. 85, No. 2), Kentucky Library Research Collections
Kentucky Warbler (Vol. 85, No. 2), Kentucky Library Research Collections
Kentucky Warbler
No abstract provided.
Effects Of Early Spring Growth Annual Ryegrass Pasture Consumption On Parameters Associated With Laminitis In Horses, Morgan Nicole Akers
Effects Of Early Spring Growth Annual Ryegrass Pasture Consumption On Parameters Associated With Laminitis In Horses, Morgan Nicole Akers
Masters Theses & Specialist Projects
Ten adult Quarter Horses (5 mares and 5 geldings) were placed in dry lot for 90 days and allowed free choice access to a diet consisting of average quality orchard grass hay, salt and water. The horses were then allowed free choice access to early-growth annual ryegrass pasture, salt and water for a 28 day period. Random hay and grass samples were analyzed for nutrient content. Blood samples were collected at 6 am, 8 am, 6 pm, and 8 pm on the final day of hay consumption and on the 4th, 9th and 28th days of grass consumption. Samples were …
A Comparative Ecological Study Of Two Sister Species Of Darters In Kentucky, Etheostoma Kantuckeense And Etheostoma Lawrencei, Bjorn Victor Schmidt
A Comparative Ecological Study Of Two Sister Species Of Darters In Kentucky, Etheostoma Kantuckeense And Etheostoma Lawrencei, Bjorn Victor Schmidt
Masters Theses & Specialist Projects
Etheostoma kantuckeense and E. lawrencei are former members of the wide ranging E. spectabile species complex. Etheostoma kantuckeense is endemic to the Barren River Basin in Southern Kentucky and Northern Tennessee, while E. lawrencei occurs in the Green River, Salt River, and Cumberland River Basins of Central and Eastern Kentucky. Isolation of populations within these drainages has allowed for a relatively recent evolutionary divergence, leading to slight differences in morphology. This study was conducted to address if geographical isolation has led to measurable differences in the ecology of these two species. In particular, habitat preference across three spatial scales and …
Protecting Walden Pond: A Step Towards Defending Ordinary Nature In The United States, Jessie L. Magee
Protecting Walden Pond: A Step Towards Defending Ordinary Nature In The United States, Jessie L. Magee
Student Research Conference Select Presentations
No abstract provided.
Faulkner The Humanist: How His Nobel Prize Acceptance Speech Changed How We Interpret "Barn Burning", Jessie L. Magee
Faulkner The Humanist: How His Nobel Prize Acceptance Speech Changed How We Interpret "Barn Burning", Jessie L. Magee
Student Research Conference Select Presentations
No abstract provided.
Elrod, Scott & Kevin Ming (Fa 388), Manuscripts & Folklife Archives
Elrod, Scott & Kevin Ming (Fa 388), Manuscripts & Folklife Archives
FA Finding Aids
Finding aid and full-text scan of papers (Click on “Additional Files” below) for Folklife Archives Project 388. Papers: "Bob Fleming: A Life History" written by Scott Elrod and "An Incomplete Life History of One Kentucky Sharecropper" written by Kevin Ming for a Western Kentucky University folk studies class.
Henning, Jason (Fa 399), Manuscripts & Folklife Archives
Henning, Jason (Fa 399), Manuscripts & Folklife Archives
FA Finding Aids
Finding aid only for Folklife Archives Project 399. Paper: "Mrs. Lucille Whitson" written by Jason Henning for a Western Kentucky University folk studies class.
Wku Scholar, Office Of Sponsored Programs, Western Kentucky University
Wku Scholar, Office Of Sponsored Programs, Western Kentucky University
WKU Scholar
No abstract provided.
Comparison Of Gene Ontology Term Annotations Between E.Coli K12 Databases, Reddysailaja Marpuri
Comparison Of Gene Ontology Term Annotations Between E.Coli K12 Databases, Reddysailaja Marpuri
Student Research Conference Select Presentations
The objective of this project was to get up-to-date functional information on all genes of E.coli K12 strains based on Genome Ontology terms. Gene Ontology is described by a defined library of terms related the biological process, cellular components and molecular functions of a gene in an organism. The genome sequence of an organism gains its value when it is annotated with gene ontology terms, which bridges the gap from the sequence to the biology of an organism. Since we use annotated gene database in the prediction of the function of newly sequenced genes, it is important to have databases …
39th Annual Wku Student Research Conference, Student Research Council, Western Kentucky University
39th Annual Wku Student Research Conference, Student Research Council, Western Kentucky University
Student Research Conference Select Presentations
No abstract provided.
Kentucky Warbler (Vol. 85, No. 1), Kentucky Library Research Collections
Kentucky Warbler (Vol. 85, No. 1), Kentucky Library Research Collections
Kentucky Warbler
No abstract provided.
Prospecting For Mammalian Chemical Signals Via Solventless Extraction Techniques: An Elephantine Task, Thomas Goodwin, Bruce A. Schulte
Prospecting For Mammalian Chemical Signals Via Solventless Extraction Techniques: An Elephantine Task, Thomas Goodwin, Bruce A. Schulte
Biology Faculty Publications
In contrast to a plethora of known insect pheromones, a paucity of mammalian pheromones has been identified, two of which have been in elephants (Albone, 1984; Brown and Macdonald, 1985; Wyatt, 2003; Burger, 2005). Elephants possess one of the world’s best chemosensory systems, due in no small measure to their prehensile trunk. The trunk is not only the gateway to smelling (primary olfaction), but also the means by which chemical signals are conveyed from their source to the openings of the vomeronasal organ ducts in the roof of the mouth (the flehmen response; secondary olfaction) (Rasmussen, 1999). The late L. …
Investigation Of A Fresh African Elephant Carcass By Conspecifics, Christen Merte, Katie Gough, Bruce A. Schulte
Investigation Of A Fresh African Elephant Carcass By Conspecifics, Christen Merte, Katie Gough, Bruce A. Schulte
Biology Faculty Publications
This examination of elephant bones and ivory indicates that elephants show an elevated level of interest in conspecifics over other dead animals. Elephants do not seem to express special interest in dead kin but rather they appear to have a generalized response to injured, dying and deceased conspecifics (Douglas Hamilton et al. 2006, McComb et al. 2006). The present study reports the behaviour of a group of elephants in response to a euthanized adult male elephant that suffered severe wounds inflicted by a conspecific male. Most of the observations from previous studies have been on females and female group members. …
What's In A Word? On Reading--And Misreading--Alfred Russel Wallace, Charles H. Smith
What's In A Word? On Reading--And Misreading--Alfred Russel Wallace, Charles H. Smith
DLPS Faculty Publications
No abstract provided.
On The Monkeys Of The Amazon (1852), Alfred Russel Wallace
On The Monkeys Of The Amazon (1852), Alfred Russel Wallace
Alfred Russel Wallace Classic Writings
No abstract provided.
On The Tendency Of Varieties To Depart Indefinitely From The Original Type (1858), Alfred Russel Wallace
On The Tendency Of Varieties To Depart Indefinitely From The Original Type (1858), Alfred Russel Wallace
Alfred Russel Wallace Classic Writings
No abstract provided.
On The Law Which Has Regulated The Introduction Of New Species (1855), Alfred Russel Wallace
On The Law Which Has Regulated The Introduction Of New Species (1855), Alfred Russel Wallace
Alfred Russel Wallace Classic Writings
No abstract provided.
Isolation Of A 3-Methylindole-Producing Bacterium From A Swine Waste Lagoon, Michelle L. Fusting
Isolation Of A 3-Methylindole-Producing Bacterium From A Swine Waste Lagoon, Michelle L. Fusting
Mahurin Honors College Capstone Experience/Thesis Projects
With an increase in animal production closer to populated areas, odorants from animal waste are a rapidly rising concern. 3-Methylindole (3-MI) is an odorant produced from the biodegradation of L-tryptophan by bacteria in animal waste. Currently, no 3-MI producing bacterium has been isolated from swine waste, and isolation of such an organism would provide insight into production and regulation of 3-MI. Therefore, an experiment was designed to isolate a 3-MI producer based on previous work which indicates the presence of Fe(III) increases 3-MI levels. An Enterococcus sp. was isolated from WKU's primary swine waste lagoon in rich, anaerobic medium plus …
The Influence Of Spatial Scale On Landcover And Avian Community Relationships Within The Upper Green River Watershed, Ky, Cabrina L. Hamilton
The Influence Of Spatial Scale On Landcover And Avian Community Relationships Within The Upper Green River Watershed, Ky, Cabrina L. Hamilton
Mahurin Honors College Capstone Experience/Thesis Projects
Landscape ecology studies are needed to aid land managers and conservationists in developing management plans that will effectively improve avian population trends. This study uses riparian avian point count survey data and landcover data to examine the possible relationships between riparian avian communities and landcover within the Upper Green River watershed. How avian-landcover relationships change with increasing spatial scale is also examined. Results showed unexpected avian-landcover relationships for specific species. A landcover gradient from open and successional habitat to closed, forest habitat was most prevalent in the study area and explained most of the variation within the avian datasets. Riparian …
Effects Of Drought The Lipid Content In Fundulus Catenatus, Angelena Edwards
Effects Of Drought The Lipid Content In Fundulus Catenatus, Angelena Edwards
Mahurin Honors College Capstone Experience/Thesis Projects
During severe drought, small streams often dry to small isolated pools with subsequent high densities of fishes. Under such conditions, fish may be stressed by high temperatures, low food availability, and lack of refugia from predators. I was interested in whether fish restricted to isolated pools burn more calories than they take in, resulting in a loss of storage lipids (high energy molecules) in their bodies. During the 2007 drought, I collected Fundulus catenatus (northern studfish) from small stream communities in the Drake’s Creek watershed in south central Kentucky. I examined storage lipid content by processing each fish through a …
Curing Nature-Deficit Disorder: How Environmental Education Helps Kids Learn, Jamie Leigh Langley
Curing Nature-Deficit Disorder: How Environmental Education Helps Kids Learn, Jamie Leigh Langley
Mahurin Honors College Capstone Experience/Thesis Projects
Walk into any public school and talk with the children about their experiences in nature and you will begin to see a pattern. Children have made few connections with the world around them. They do not spend much time outdoors and the time they do spend outdoors is not spent interacting directly with nature. Why does this matter? Look at these same kids and you will see another pattern emerging: Attention-Deficit Disorder, depression, obesity, emotional problems, etc. While not all of these problems are directly caused by a lack of interaction with the natural world, current research shows that there …
Quantum Dot Immuno-Conjugates Allow For Reliable Photo-Stable Detection Of Intracellular Stages Of Toxoplasma Gondii, Natalia Barahona Guerrero
Quantum Dot Immuno-Conjugates Allow For Reliable Photo-Stable Detection Of Intracellular Stages Of Toxoplasma Gondii, Natalia Barahona Guerrero
Mahurin Honors College Capstone Experience/Thesis Projects
Luminescent quantum dot nanoparticles have emerged as a highly effective alternative to organic fluorescence probes in a variety of applications employing the use of immunoconjugates. In the present study, we have successfully used quantum dot technology for the immunofluorescent detection of intracellular stages of Toxoplasma gondii in a CV-1 mammalian cell line. This assay will allow us to investigate the question of whether selenium and other antioxidants have a direct impact on the intracellular cycle of the parasite. A Lab-Tek cell culture system was used to determine optimal concentrations of primary and secondary antibodies. Infected CV-1 monolayers were fixed in …