Life Sciences Commons^™

Expression Profiling Identifies Novel Hh/Gli-Regulated Genes In Developing Zebrafish Embryos, Sadie A. Bergeron, Luis A. Milla, Rosario Villegas, Meng-Chieh Shen, Shawn M. Burgess, Miguel L. Allende, Rolf O. Karlstrom, Verónica Palma

Biology Department Faculty Publication Series

The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. The zebrafish is a powerful genetic model for the study of Hh signaling during embryogenesis, as a large number of mutants that affect different components of the Hh/Gli signaling system have been identified. By performing global profiling of gene expression in different Hh/Gli gain- and loss-of-function scenarios we identified known (e.g., ptc1 and nkx2.2a) and novel Hh-regulated genes that are differentially expressed in embryos with altered Hh/Gli signaling …

Farmer Literacy Practices: A Comparative Study Of Farmers In Kurnool District Of Andhra Pradesh, India, Konda Reddy Chavva

Master's Capstone Projects

ABSTRACT The goal of the study was to understand farmer literacy practices, and how farmer participants perceive the usefulness of Farmer Water School (FWS) training. Studying the farmer literacy practices was to help identify farmer friendly methods, and design effective messages for dissemination on crop choices, decisions, and sustainable groundwater management. To understand the usefulness of FWS training to farmers, a comparative study of FWS participants and non-FWS pa11icipants' perceptions on crop-water management, crop choices, and agriculture practices was undertaken. The study focused on the farmers of Kurnool district of Andhra Pradesh, India.

The research questions driving this study included: …

Holyoke Dam, Connecticut River, 2008, Brett Towler

Fish Passage Data Archive

Holyoke Dam

Connecticut River

Massachusetts

Year data collected: 2008

2008 Chart Book: Weed Management, Hilary A. Sandler

Cranberry Chart Book - Management Guide

No abstract provided.

Impact Of Chemical And Physical Properties On The Ability Of Antioxidants To Inhibit Lipid Oxidation In Foods, Jean Alamed

Masters Theses 1911 - February 2014

Lipid oxidation is a major problem in foods resulting in alteration of texture, appearance, off flavors, aroma and decreased nutritional quality. The ability of compounds to inhibit lipid oxidation in foods is dependent on both physical and chemical properties. The effects of heating (50-90°C), ethylenediaminetetraacetic acid (EDTA), and calcium on the oxidative and physical stability of salmon oil-in-water emlusions were investigated in the first study. Oil-in-water emulsions were prepared with 2% salmon oil, stabilized by 0.2% Brij 35 at pH 7. Above 2.5 μM, EDTA dramatically decreased lipid oxidation in all samples. Addition of calcium to emulsions containing 7.5 μM …

Beginner School 2008 - Cranberry Nutrition And Fertilizers, Carolyn J. Demoranville

Cranberry Station Extension meetings

No abstract provided.

Beginner School 2008 - Cranberry Irrigation, Peter Jeranyama

Cranberry Station Extension meetings

No abstract provided.

Beginner School 2008 - Cranberry Disease Management, Frank Caruso

Cranberry Station Extension meetings

No abstract provided.

Beginner School 2008 - Weed Management In Cranberry Production - 101, Hilary A. Sandler

Cranberry Station Extension meetings

No abstract provided.

Research Update Meeting 2008 - Weed Ipm Management Update 2008, Hilary A. Sandler

Cranberry Station Extension meetings

No abstract provided.

Pesticide Safety 2008 - Groundwater Protection Regulations (Zone Ii), Brian Wick

Cranberry Station Extension meetings

No abstract provided.

Pesticide Safety 2008 - Callisto And Kerb, Hilary A. Sandler

Cranberry Station Extension meetings

No abstract provided.

Pesticide Safety 2008 - Ppe Review, Keeping Safe And Pesticide Update, Part Ii, Martha Sylvia

Cranberry Station Extension meetings

No abstract provided.

Callisto Use In Massachusetts, 2008: Results Of A Grower Survey, Hilary A. Sandler, Natalie Guerin

Cranberry Station Research Reports and Surveys

No abstract provided.

Cranberry Production Guide, Hilary A. Sandler, Carolyn J. Demoranville

Cranberry Production Guide

No abstract provided.

Actin Depolymerizing Factor Is Essential For Viability In Plants, And Its Phosphoregulation Is Important For Tip Growth, Rc Augustine, L Vidali, Kp Kleinman, M Bezanilla

Biology Department Faculty Publication Series

No abstract provided.

Rapid Large-Scale Evolutionary Divergence In Morphology And Performance Associated With Exploitation Of A Different Dietary Resource, Anthony Herrel, Katleen Huyghe, Bieke Vanhooydonck, Thierry Backeljau, Karin Breugelmans, Irena Grbac, Raoul Van Damme, Duncan J. Irschick

Biology Department Faculty Publication Series

Although rapid adaptive changes in morphology on ecological time scales are now well documented in natural populations, the effects of such changes on whole-organism performance capacity and the consequences on ecological dynamics at the population level are often unclear. Here we show how lizards have rapidly evolved differences in head morphology, bite strength, and digestive tract structure after experimental introduction into a novel environment. Despite the short time scale (≈36 years) since this introduction, these changes in morphology and performance parallel those typically documented among species and even families of lizards in both the type and extent of their specialization. …

Tissue-Specific Requirements For Specific Domains In The Ferm Protein Moe/Epb4.1i5 During Early Zebrafish Development, Arne K. Christensen, Abbie M. Jensen

Biology Department Faculty Publication Series

Background

The FERM domain containing protein Mosaic Eyes (Moe) interacts with Crumbs proteins, which are important regulators of apical identity and size. In zebrafish, loss-of-function mutations in moe result in defects in brain ventricle formation, retinal pigmented epithelium and neural retinal development, pericardial edema, and tail curvature. In humans and mice, there are two major alternately spliced isoforms of the Moe orthologue, Erythrocyte Protein Band 4.1-Like 5 (Epb4.1l5), which we have named Epb4.1l5long and Epb4.1l5short, that differ after the FERM domain. Interestingly, Moe and both Epb4.1l5 isoforms have a putative C' terminal Type-I PDZ-Binding Domain (PBD). We previously showed that …

Changes In Physical Activity From Walking To School, John Sirard, Sofiya Alhassan, Tirzah Spencer, Thomas Robinson

John Sirard

No abstract provided.

Meeting Report: Moving Upstream—Evaluating Adverse Upstream End Points For Improved Risk Assessment And Decision-Making, R. Thomas Zoeller, T. J. Woodruff, L. Zeise, D. A. Axelrad, K. Z. Guyton, S. Janssen, M. Miller, G. G. Miller, J. M. Schwartz, G. Alexeeff, H. Anderson, L. Birnbaum, F. Bois, V. J. Cogliano, K. Crofton, S. Y. Euling, P. M. Foster, D. R. Germolec, E. Gray, D. B. Hattis, A. D. Kyle, R. W. Luebke, M. I. Luster, C. Portier, D. C. Rice, G Solomon, J. Vandenberg, R. Thomas Zoeller

R. Thomas Zoeller

Background Assessing adverse effects from environmental chemical exposure is integral to public health policies. Toxicology assays identifying early biological changes from chemical exposure are increasing our ability to evaluate links between early biological disturbances and subsequent overt downstream effects. A workshop was held to consider how the resulting data inform consideration of an “adverse effect” in the context of hazard identification and risk assessment. Objectives Our objective here is to review what is known about the relationships between chemical exposure, early biological effects (upstream events), and later overt effects (downstream events) through three case studies (thyroid hormone disruption, antiandrogen effects, …

Tissue-Specific Requirements For Specific Domains In The Ferm Protein Moe/Epb4.1l5 During Early Zebrafish Development, Abigail Jensen, A. K. Christensen

Abigail Jensen

Background The FERM domain containing protein Mosaic Eyes (Moe) interacts with Crumbs proteins, which are important regulators of apical identity and size. In zebrafish, loss-of-function mutations in moe result in defects in brain ventricle formation, retinal pigmented epithelium and neural retinal development, pericardial edema, and tail curvature. In humans and mice, there are two major alternately spliced isoforms of the Moe orthologue, Erythrocyte Protein Band 4.1-Like 5 (Epb4.1l5), which we have named Epb4.1l5long and Epb4.1l5short, that differ after the FERM domain. Interestingly, Moe and both Epb4.1l5 isoforms have a putative C' terminal Type-I PDZ-Binding Domain (PBD). We previously showed that …

Network Discovery Pipeline Elucidates Conserved Time Of Day Specific Cis-Regulatory Modules, Samuel P. Hazen, T. P. Michael, T. C. Mocker, G. Brenton, C. Mcentee, A Byer, J. D. Trout, H. D. Priest, C. M. Sullivan, R. Shen, S. A. Givan, M. Yanovsky, F. Hong, S. A. Kay, J. A. Chory

Samuel P Hazen

Correct daily phasing of transcription confers an adaptive advantage to almost all organisms, including higher plants. In this study, we describe a hypothesis-driven network discovery pipeline that identifies biologically relevant patterns in genome-scale data. To demonstrate its utility, we analyzed a comprehensive matrix of time courses interrogating the nuclear transcriptome of Arabidopsis thaliana plants grown under different thermocycles, photocycles, and circadian conditions. We show that 89% of Arabidopsis transcripts cycle in at least one condition and that most genes have peak expression at a particular time of day, which shifts depending on the environment. Thermocycles alone can drive at least …

Comparing Gala Apple Trees On Different Strains Of B.9, M.9, M.26, And Other Rootstocks: An Update On The 2002 Nc-140 Apple Rootstock Trial, Wesley Autio, James Krupa, Jon Clements

Wesley Autio

No abstract provided.

Comparing Mcintosh Apple Trees On Several Geneva And Supporter Rootstocks: An Update On The 1999 Nc-140 Dwarf Apple Rootstock Trial, Wesley Autio, James Krupa, Jon Clements

Wesley Autio

No abstract provided.

Enhancing Return Bloom Of Honeycrisp Apples With Ethephon, Wesley Autio

Wesley Autio

No abstract provided.

Effect Of Surfactants On Bioherbicidal Activity Of Alternaria Helianthi On Multiple-Seeded Cocklebur, Prasanta C. Bhowmik, H. K. Abbas, D. Sanyal

Prasanta C. Bhowmik

Abstract: Multiple-seeded cocklebur (Xanthium strumarium L.) is a biotype which has different morphology and higher seedling production ability than common cocklebur. Greenhouse studies were conducted to investigate the bioherbicidal activity of Alternaria helianthi (Hansf.) Tubaki and Nishih. on multiple-seeded cocklebur as affected by various rates of Tenkoz COC® (crop oil concentrate), Activator 90® (non-ionic surfactant), BAS 9050 0 S® (methylated oil), Silwet L-77® (organosilicone surfactant) and Top film® (natural based surfactant). Taking X as the recommended rate for each surfactant, 0-X, ¼-X, ½-X, X and 2-X rates were used for each of the surfactants. Surfactants were added to the conidial …

Can Carbaryl Enhance Ethephon’S Value As A Late-Season Thinner?, Wesley Autio, James Krupa, Winfred Cowgill Jr.

Wesley Autio

No abstract provided.

Comparative Analysis Of Multiple Disease Resistance In Ryegrass And Cereal Crops, Young-Ki Jo, Reed Barker, William Pfender, Scott Warnke, Sung-Chur Sim, Geunhwa Jung

Geunhwa Jung

Ryegrass (Lolium spp.) is among the most important forage crops in Europe and Australia and is also a popular turfgrass in North America. Previous genetic analysis based on a three-generation interspecific (L. perenne 9 L. multiflorum) ryegrass population identified four quantitative trait loci (QTLs) for resistance to gray leaf spot (Magneporthe grisea) and four QTLs for resistance to crown rust (Puccinia coronata). The current analysis based on the same mapping population detected seven QTLs for resistance to leaf spot (Bipolaris sorokiniana) and one QTL for resistance to stem rust (Puccinia graminis) in ryegrass for the first time. Three QTLs for …

Comparing Mcintosh Apple Trees On Geneva And Supporter Rootstocks: An Update On The 1999 Nc-140 Semidwarf Apple Rootstock Trial, Wesley Autio, James Krupa, Jon Clements

Wesley Autio

No abstract provided.

Cancer Prevention By Tea And Tea Polyphenols, Hang Xiao, C.S. Yang, J. Ju, G. Lu, X. Hao, S. Sang, J. Lambert

Hang Xiao

The inhibition of tumorigenesis by tea extracts and tea polyphenols has been demonstrated in different animal models, including those for cancer of the skin, lung, oral cavity, esophagus, stomach, small intestine, colon, bladder, liver, pancrease, prostate, and mammary glands. Caffeine is also active in inhibition of tumorigenesis on the skin, lung, and perhaps other organs. In spite of many in vitro and in vivo studies, the molecular mechanisms for the cancer preventive actions of these compounds are not clearly known. The relationship between tea consumption and cancer risk has not been conclusively, and the relationship may become more clear if …