Life Sciences Commons^™

Overcoming Detrimental Potato Fungi In Potato Fields With The Secondary Metabolites Of Naturally Occurring Steptomyces, Hansan Jones, Jacob Anderson, Erik Kemp, Brad Geary, Matthew Madsen, Ryan Stewart

Library/Life Sciences Undergraduate Poster Competition 2022

• Fungal disease Silver scurf can cause 13% water loss and give poor aesthetic appeal, both of which reduce farmers profits (1,2).
• Pythium leak can result in up to 50% total loss of potatoes in storage (3)
• Streptomyces is the right candidate to mitigate or eliminate these losses because of its ability to survive in soil (4) and its history as a proven biocontrol for other plant pathogens (5).

The Mrna/Protein Relationship Is Fluid And Changes Across Tissue And Diseased States, Jose Humberto Giraldez Chavez, Sam Payne

Library/Life Sciences Undergraduate Poster Competition 2022

• Cancer is a dysregulated cell
• Molecular typing via DNA/RNA/protein
• Is RNA a proxy for cell?

Staying Hydrated: A Comparative Analysis Of Humectants In Human Skin, Ayden Olsen, Rachel Prince, Craig Reeves, Cassie Peterson, Jason Adams

Library/Life Sciences Undergraduate Poster Competition 2022

Humectants are an important class of compounds that attract and retain water within a cell. When mixed with water to create wetting solutions, humectants can prevent desiccation of cadaveric specimens. Recognizing a relative scarcity of comparative studies analyzing the effects of various wetting solutions on post preservation cadaveric maintenance, we utilized wet-dry analysis in order to compare the effects of four common humectants on water retention in human skin tissue. We created a concentration gradient for each humectant to identify the optimal concentrations of each compound for water retention, after which we compared water retention in tissue at the optimal …

Does Bathing After Sexual Assault Or Time Elapsed Have A Greater Effect On The Development Of Codis Eligible Dna Profiles?, Emily Black, Sam Payne, Julie Valentine, Leslie Miles

Library/Life Sciences Undergraduate Poster Competition 2022

Which has a greater effect on the development of CODIS eligible DNA profiles from SAKs – bathing/showering status of the victim or time between the assault and examination?

Comparison Of Tardigrade Extraction Methods, Abigail Andros

Library/Life Sciences Undergraduate Poster Competition 2022

It is a time-consuming process to pick tardigrades for an experiment. The standard method is to add water to the sample, then look through it and pick out tardigrades with a micropipette or small wire loop (Tsujimoto et al. 2015).

Improving The Germination Rate Of Gambel Oak (Quercus Gambelii) For Mineland Restoration, Ethan Ostraff, Christopher Miller, April Hulet, Bradley Geary, Kate Ruebelmann, Matthew Madsen

Library/Life Sciences Undergraduate Poster Competition 2022

Quercus gambelii Nutt. (Gambel oak) is an ecologically important species that provides food and shelter for many wildlife species. In areas impacted by disturbance, Q. gambelii is often the first woody perennial species to reestablish (USFS, 2016). The use of this species could be beneficial for the reclamation of mine sites in mountain shrubland areas of the western United States. However, due to the recalcitrant nature of these acorns (i.e. seeds that do not survive after drying or freezing), viability can quickly be lost after the acorns are harvested. Additionally, invasive weevils (Family Curculionidae) infest and kill oak acorns. These …

The Metabolic Effects Of Exercise And A Pre-Exercise Snack During A 30-Hour Fast, Katelynn Hales, Hil'ilei Chan, Landon S. Deru, Jake Moss, Bruce W. Bailey Ph.D.

Library/Life Sciences Undergraduate Poster Competition 2022

As incidence rates of chronic illnesses continue to increase, many pharmacological and lifestyle interventions have been undertaken to pinpoint effective treatment and prevention tools to combat them. One such intervention of recent interest includes the use of fasting. Ketones, a product of fat breakdown, are thought to be a key player in some of the health benefits achieved through fasting. Despite potential benefits, adhering to a fasting regimen can be difficult. While it is generally well-tolerated, some experience negative side effects,² indicating potential issues with long-term adherence. Heilbronn et al. suggest that a small meal on fasting days may be …

A Chromosome-Scale Assembly Of The Djulis (Chenopodium Formosanum) Genome, An Emerging Orphan Crop From Taiwan, Peter J. Maughan, Eric N. Jellen, John Sproul, Karol Krak, Tzu-Yun Huang, Tzu Che Lin, Beatriz Navarro Dominguez, Yung-Fen Huang, Kate Jaggi, David E. Jarvis

Library/Life Sciences Undergraduate Poster Competition 2022

Djulis (Chenopodium formosanum Koidz.) is a semi-domesticated Taiwanese native crop. It is a BCD-genome hexaploid (2n = 6x = 54) relative of the Andean-native allotetraploid (AABB) quinoa (C. quinoa). Djulis has been grown in a relatively small area by aboriginal Taiwanese, who use it primarily as a fermentation starter to produce ritual alcoholic beverages. Djulis’ seed protein, like that of quinoa, is complete in terms of its human dietary essential amino acid profile; the seed also offers a wide variety of nutritionally important vitamins and minerals. These nutritional attributes have attracted international attention as a novel, healthy grain option. We …

Whole-Body Vibration Alleviates Symptoms Of Morphine Withdrawal, Gavin C. Jones, Christina A. Small, Dallin Z. Otteson, Scott C. Steffensen

Library/Life Sciences Undergraduate Poster Competition 2022

Whole body vibration at 80 Hz has been shown to blunt neuropathological markers and behavioral symptoms of alcohol dependence Here, we evaluate its ability to ameliorate symptoms of morphine use and withdrawal.

The Role Of Cd5 In Cd4+ T Cell Metabolism, Joshua Bennett, Kiara Whitley, Claudia Freitas Phd, Christopher Haynie, Carlos Moreno, Scott Weber

Library/Life Sciences Undergraduate Poster Competition 2022

T cells serve a key role in the immunological response in the adaptive system. Different receptors present on the T cell have certain roles and are able to either inhibit or stimulate signaling which consequently regulates the function and metabolism of the cell. CD5 is an inhibitory co receptor expressed on the surface of T cells known to regulate thymocyte selection and TCR signaling . Our goal is to better understand the effects of CD5 regulation in metabolism. Using metabolic flux assays, we found that CD5KO naïve T cells have increased glycolysis and mitochondrial respiration in comparison to wild type …

Reviewing The Effects Of Human-Induced Limb Damage In Crabs, Jacob B. Spencer, Blaine D. Griffen

Library/Life Sciences Undergraduate Poster Competition 2022

Limb damage in crabs comes in various forms, each with unique consequences. Brachyuran crabs shed limbs as a defensive reflex, with natural breakage occurring along a plane, otherwise known as autotomy. In addition to autotomy, crabs commonly lose limbs due to fishing practices such as declawing. In many areas, taking the limbs and releasing the crab is a common practice. The logic is that the populations won’t decline if the crab is put back. Other practices such as nicking, or cutting the main claw tendon, are used to restrict claw movement. Various effects of these fishery practices have been documented …

Validity Of Ultrasound Imaging For Intrinsic Foot Muscle Cross-Sectional Area Measurements Demonstrated By Strong Agreement With Mri, Dallin C. Swanson, Joshua K. Sponbeck, Derek A. Swanson, Connor D. Stephens, Steven P. Allen, Ulrike H. Mitchell, James D. George, A. Wayne Johnson

Library/Life Sciences Undergraduate Poster Competition 2022

Intrinsic foot muscles maintain foot structural integrity and contribute to functional movement, posture and balance Thus, assessing intrinsic foot muscle size and strength are important One way to assess strength of a muscle is by measuring its cross sectional area ( Magnetic resonance imaging ( and ultrasound ( are two modalities allowing for visualization of these muscle bodies MRI has been shown to accurately image the individual muscles but is costly and time consuming US imaging may provide an alternative that is less costly and more readily available The purpose of this study was to investigate the validity and reproducibility …

Overcoming Detrimental Potato Fungi With The Secondary Metabolites Of Naturally Occurring Streptomyces In A Greenhouse, Hansan Jones, Jacob Anderson, Erik Kemp, Brad Geary, Matthew Madsen, Ryan Stewart

Library/Life Sciences Undergraduate Poster Competition 2022

• Fungal disease Silver scurf can cause 13% water loss and give poor aesthetic appeal, both of which reduce farmers profits (1,2).
• Pythium leak can result in up to 50% total loss of potatoes in storage (3).
• Streptomyces is the right candidate to mitigate or eliminate these losses because of its ability to survive in soil (4) and its history as a proven biocontrol for other plant pathogens (5).

Morphological Changes Of The Asian Shore Crab Across Latitudes, Ainslee Mcmullin, Blaine D. Griffen

Library/Life Sciences Undergraduate Poster Competition 2022

The Asian shore crab, Hemigrapsus sanguineus , is an invasive species that has rapidly spread across the Eastern United States coastline. First observed in North America in 1988, its range currently extends from Maine to North Carolina. H. sanguineus has adapted very well to this region and has displaced several native species as the dominant crab in rocky intertidal habitats. Although the Asian shore crab’s biology and interactions with native species has been well studied, larger scale impacts (economic, potential further spread, community ecology, etc.) are under researched. We collected specimen samples of H. sanguineus throughout its entire East coast …

Species Invasion Vs. Abundance In The Northern And Southern Regions Of Lake Powell, Amanda Lebarge, Mark Belk

Library/Life Sciences Undergraduate Poster Competition 2022

Lake Powell is a dynamic system, evidenced by its yearly fluctuations in water level. In the last 20 years, this reservoir has experienced invasions from two different invasive species: the gizzard shard, and quagga mussel. Due to the unique nature of Lake Powell, our research seeks to understand if there were catastrophic effects of these invasions on fish biomass and abundance patterns, and do these impacts vary based on region? We hypothesize that both species will have a major impact in all regions on the native species in Lake Powell; however, the southern region will be more catastrophic.

A Ketogenic Diet Enhances Hippocampal Mitochondrial Efficiency, Cali E. Warren, Erin R. Saito, Benjamin T. Bikman

Library/Life Sciences Undergraduate Poster Competition 2022

Mitochondrial dysfunction and cognitive impairment are common symptoms in many neurologic disorders, as well as in nonpathological aging. Ketones have been suggested as therapeutic for their relevance in epilepsy and other neurodegenerative diseases and psychiatric disorders such as Alzheimer’s and Parkinson’s disease, schizophrenia, and major depressive disorder.

New Treatment For Multiple Sclerosis Could Halt Disease Progression Without Weakening Immune System, Carter Helquist, Dario Mizrachi

Library/Life Sciences Undergraduate Poster Competition 2022

• Multiple Sclerosis (MS) is a debilitating neurological and autoimmune disease in which immune cells cause demyelination of axons in nervous tissue.
• Current treatments for the disease are principally aimed at weakening the immune system to therefore weaken the autoimmune attack on the brain. This leaves patients prone to other sicknesses.
• We seek a treatment that prevents the immune cells from entering the central nervous system (CNS) thereby protecting its cells.
• We can prevent immune cells from entering the CNS by strengthening the blood brain barrier through targeting claudin 5 proteins in the tight junctions.
• This new treatment could mean increased …

Chimeric Claudins Reveal Role In Neural Tube Defects, Wesley Allen, Nathan Beckett, Emma Brenchley, Jacob Wengler, Lauren Hall, Cailey Winn, Meredith Mann, Sion Jung, Spencer Thacker, Rachel May, Dario Mizrachi, Micheal Stark

Library/Life Sciences Undergraduate Poster Competition 2022

Claudins (CLDN), a family of proteins found in the tight junction, play a major role in membrane permeability. While claudin disruption is known to contribute to the formation of neural tube defects (NTD), current research methods rely heavily on a non-specific toxin, CPE, when exploring the importance of CLDNs within neural tube formation. This makes it difficult to identify individual CLDN’s contribution to NTD formation, creating a need for a more specific method.

Potential Regulation Of Breast Cancer Invasion By Thymidine Kinase 1, Eliza E. Bitter, Rachel M. Morris, Toni O. Mortimer, Kai Barlow, Abigail Schekall, Michelle H. Townsend, Jonathan Skidmore, Brett E. Pickett, Kim L. O'Neill

Library/Life Sciences Undergraduate Poster Competition 2022

Breast cancer is the most common cancer in women and is largely treatable within the early stages of the disease. However, patient mortality drastically declines as the tumor begins to invade other tissues and metastasize, making aggressive phenotypes especially problematic to treat. Such treatment typically requires an aggressive and decisive multidisciplinary approach. The recent expansion of immunotherapy as a viable treatment option has greatly improved treatment outcomes, especially with aggressive breast cancer phenotypes. Thymidine kinase 1 (TK1) is a DNA salvage pathway enzyme that is highly expressed during S phase and involved in cell cycle repair. Past studies indicated that …

Ancestral State Reconstruction Of Oviposition Techniques In New World Stick Insects, Ellie Mcgregor, Jackson Linde, Michael F. Whiting

Library/Life Sciences Undergraduate Poster Competition 2022

Phasmids, commonly known as stick bugs, are unique and interesting creatures, both phenotypically and genotypically. Their cryptic abilities are what draws most people to them, but their oviposition techniques, or how they disperse eggs, has become a new source of interest. While most phasmids are known to flick or drop their eggs from the canopy, there are several other techniques including inserting the eggs into the soil or gluing them to a substrate. New world phasmids have not been thoroughly studied, especially in understanding which technique was ancestral. The purpose of this paper was to construct a phylogenetic tree to …

Rising Recess Temperatures: Quantifying The Cooling Effect Of School Parks, Nicholas Kendall, Xuhui Lee

Library/Life Sciences Undergraduate Poster Competition 2022

Many schools in the US are currently placed in urban heat islands. Children attending these schools are thought to be at greater risk to heat stress related health concerns. We used mobile heat sensors to see if there was a quantifiable difference between the playgrounds and parks within and between two schools with differing park sizes.

Rangeland Legacies Of Utah, Ethan Ostraff, Amber Johnson, Samuel Knuth, Rebecca Black

Library/Life Sciences Undergraduate Poster Competition 2022

In the heart of Utah lies a rich history of rangeland sciences and land use. Ephraim, Utah and the surrounding mountains and valleys have long been a valuable source of shelter and food for the peoples that have inhabited the region. Bands of Paiute and Ute Native Americans called this valley home until the 1850’s when Scandinavian pioneers began settling it. European settlers brought farming techniques that transformed the landscape.

The Effect Of Wearable Activity Monitor Presence On Step Counts, William B. Tayler, James D. Lecheminant, Jospeh Price, Christian P. Tadje

Faculty Publications

Objective: In this study, we tested the effect of wearable activity monitors and tracking on physical activity over 2 weeks.

Methods: Ninety young adults participated. Prior to initiation of the study, each participant was asked to download an iPhone app that tracked physical activity level (step counts) but were not told the app’s purpose. Each participant was then randomly assigned to one of 3 groups (N=30/group): (1) measurement awareness, (2) measurement awareness+track/record, or (3) control. Participants in the measurement awareness and the measurement awareness+track/record groups were given a pedometer to wear for 2 weeks. Additionally, participants in the measurement awareness+track/ …

A Comparison Of The Effects Of Heat Therapy And Exercise Training On Vascular Function During Passive And Active Exercise, Taysom Erica Wallace

Theses and Dissertations

Recent evidence suggests that heat, a major byproduct of exercise, may be the mediator for many vascular adaptations that come from exercise. Thus, heat therapy that increases muscle temperature in a comparable way to exercise may be an advantageous alternative for enhancing cardiovascular health in individuals where treatment with exercise is either not possible or undesired. PURPOSE: Compare the effects of exercise and heat training on resistance artery function at rest and during exercise. METHODS: Thirty-five (18 female) healthy, untrained subjects completed a 6-week training program utilizing either high intensity knee extension (KE) exercise (40 min), localized heat therapy (pulsed …

Identifying And Knocking Out Non-Visual Opsins In The Optic Tectum Of Zebrafish Larvae, Sarah Jarrett

Undergraduate Honors Theses

Deep brain photoreceptors (DBPs) are non-visual photoreceptors found in the brains of non-mammalian vertebrates like zebrafish. While using optogenetic techniques in our lab to photo-activate the ear (by expressing the light-gated channel: channelrhodopsin) in efforts of identifying optic tectum (OT) neurons that respond to and integrate auditory and visual stimuli, we found that violet light was able to elicit OT neuronal activity. OT activity was also detected in cases when visual and auditory stimulation was not possible due to removal of the eyes and absence of the exogenously expressed channelrhodopsin, respectively. Analyzing OT single-cell sequencing data of 7day post fertilization …

Utilizing Isothermal Titration Calorimetry For Measuring Beta-Galactosidase Activity In Liquid Dairy Products, Eliza Anne Brock

Theses and Dissertations

This research explores Isothermal Titration Calorimetry as a method for measuring beta-galactosidase activity directly and continuously in milk, sweet whey, sweet whey permeate, acid whey, and acid whey permeate. Beta-galactosidase in various concentrations was injected into each of the liquid dairy products spiked with lactose to verify if the heat rate from the enzymatic reaction could be observed. In addition, a consistent concentration of beta-galactosidase was injected into various concentrations of lactose in the products, to observe the heat rates from the enzymatic reaction. There was exothermic activity that never returned to baseline demonstrated in milk, sweet whey, and sweet …

Effects Of Catharanthine On Dopamine Release In The Nucleus Accumbens And Ethanol Consumption, Emily Baldwin

Undergraduate Honors Theses

This thesis discusses the history of catharanthine and related compounds, and their potential anti-addictive properties. Current research is exploring possible mechanisms of these properties. Past studies have found catharanthine has effects on neurons that project to the mesocorticolimbic system, an area implicated in addiction. We have seen that catharanthine decreases evoked dopamine (DA) release but increases basal DA release. This is the first study to investigate catharanthine’s effect on DA transmission in vivo. Using microdialysis, we determined the effect of catharanthine on DA in the nucleus accumbens of the striatum. This study determines the effect of different doses of …

Restricted Microbial Presence, Activity, And Community Structuring Within Dry Valley Soils Of Antarctica, Scott Fillerup George

Theses and Dissertations

The McMurdo Dry Valley region is the largest ice-free area of Antarctica. Harsh abiotic conditions of the polar desert ecosystem, including extreme cold, aridity, and limited nutrient availability select for unique taxa. The comparatively simple terrestrial ecosystem is well-suited for investigating edaphic influences on microbial presence, activity, and community structuring. The Dry Valleys are viewed as a useful analog for Mars astrobiology investigations. However, most biotic investigations have been focused on lower elevations, where an understanding of edaphic effects on microbial communities within its generally more favorable conditions has emerged. Transiently wetted Dry Valley water tracks may be analogous to …

Mixture Design Response Surface Methodology Analysis Of Seven Natural Bioactive Compounds To Treat Prostate Cancer, Ian Geddes Berlin

Theses and Dissertations

Natural bioactive compounds have drawn the interest of many researchers worldwide in their effort to find novel treatments, including prostate cancer (PC) treatment which is estimated to be 13.1% of all new cancer cases in the U.S. in 2021. Many of these bioactive compounds have been identified from treatments in traditional Chinese medicine (TCM), that often have multiple bioactive compounds present. However, in vitro studies frequently focus on the compounds in isolation, or in simple combinations of two compounds. We used mixture design response surface methodology (MDRSM) to assess changes in PC cell viability after 48 hours of treatment to …

Characterization Of Bacteriophage Targeting Bacillus Licheniformis In Milk Processes And Thermal Stability Of Bacteriophage During Htst Pasteurization, Jeremy Robert Arbon

Theses and Dissertations

An array of Bacillus licheniformis strains were isolated from a commercial powdered milk process. Bacteriophages exhibiting activity against B. licheniformis were isolated from cattle manure and effluent samples destined for a lagoon at a dairy farm. After sequencing, 8 of the 10 phages were found to be novel and genetically differentiated. Transmission electron scanning microscopy (TSEM) was performed. All bacteriophages were of the family Herelleviridae with contractile tail sheaths ranging from 80µm to 150µm and, surprisingly, survived a common fluid milk processing treatment used to inactivate vegetative cells. The survival of the phage after high temperature short time pasteurization of …