Life Sciences Commons^™

Multi-Omic Characterization Of The Hispanic/Latino Blood Lipidome Reveals An Additional Locus And Attenuated Genetic Prediction, Wanying Zhu, Hung-Hsin Chen, Heather M. Highland, Corey Giles, Peter J. Meikle, Joanne Curran, Joseph B. Mccormick, Susan P. Fisher-Hoch, Kari E. North

Human Genetics Publications

While lipids have been extensively investigated, genetic regulation of the circulating lipidome in diverse populations remains poorly understood. We conducted a lipidome-wide genome-wide association study (GWAS) of 830 lipid species in 2,287 Hispanic/Latino participants and performed predictive modeling across omics layers. We identified 7,593 genome-wide significant SNPs mapping to 208 genes. Conditional analysis disentangled the long-range linkage disequilibrium artifacts from the pleiotropic FADS1/2/3 cluster. Separately, we discovered an association at the GPLD1 locus for a circulating ceramide. Colocalization revealed shared genetic architecture with conventional lipids alongside distinct, species-specific pathways. Incorporating Native/Indigenous American expression quantitative trait loci …

Beyond Nutrients: Frass Fertilizer Legacy Effects For Sustainable Nematode Management In Potato–African Nightshade Rotation Systems, Emmanuel O. Anedo, Dennis Beesigamukama, Benson Mochoge, Nicholas K. Korir, Solveig Haukeland, Xavier Cheseto, Moses Nyongesa, Patrick Pwaipwai, Sevgan Subramanian, Abdou Tenkouano, Chrysantus M. Tanga

All Peer-Reviewed Publications

The utilization of insect frass fertilizer in crop production systems has recently gained significant global interest, but there has been limited evidence of its residual benefits in rotational cropping systems. The legacy effects of black soldier frass fertilizers (BSFFF), conventional organic fertilizer (SAFI), inorganic fertilizer (NPK), synthetic nematicide, and their combinations on potato cyst nematode (PCN) management under potato-African nightshade rotational farming systems were investigated. Eight treatments were evaluated: BSFFF, SAFI, chitin-fortified BSFFF (BSFFF+5chitin), NPK + nematicide, combination of BSFFF and NPK so that each supplies 50% of the nitrogen required by potato (50BSFFF+50NPK), combination of SAFI and NPK so …

Silverleaf Nightshade (Solanum Elaeagnifolium) Undergoes Guild-Specific Transcriptomic Reprogramming Against Chewing Versus Piercing Sucking Herbivory, Arunsaikumar Karrem, Matthew Terry, Jagdish Jaba, Rupesh R. Kariyat

School of Integrative Biological & Chemical Sciences Faculty Publications

Solanum elaeagnifolium (silverleaf nightshade, SLN) is a globally invasive perennial weed with reproductive plasticity and complex defence systems that significantly impact crop yields by invading fields of staple, commercial and ornamental crops. Despite being a host to multiple insect herbivores, the molecular programming enabling its rapid adaptation to defend against diverse feeding guilds remains poorly resolved. Here, we report a comprehensive de novo transcriptomic assembly and comparative analysis of S. elaeagnifolium challenged by two distinct herbivores: the piercing-sucking generalist cowpea aphid, Aphis craccivora and the chewing specialist tobacco hornworm, Manduca sexta. Differential gene expression analysis revealed a massive difference …

Exploring The Significance Of Kenya's Indigenous And Emerging Blue Foods For Sustainable Aquaculture Development. A Review, Jonathan Munguti, Mavindu Muthoka, Domitila Kyule, Esther Magondu, Kevin Obiero, Jimmy Mboya, Menaga Meenakshisundaram, Tanga M. Chrysantus, Gerald Kwikiriza, Francis K. Njonge

All Peer-Reviewed Publications

Kenya's aquaculture sector is at a pivotal stage, transitioning from a historical reliance on Nile tilapia and African catfish toward a more diversified production portfolio that integrates indigenous and emerging freshwater and marine species. This shift is increasingly recognized as essential to enhance climate resilience, food security, and ecosystem health. This systematic review synthesizes more than two decades (2000 to 31st January, 2026) of peer-reviewed literature to evaluate the biological suitability, culture performance, and socio-ecological roles of underutilized native taxa, including Ningu (Labeo victorianus), Jipe tilapia (Oreochromis jipe), freshwater prawns (Macrobrachium spp.), rabbitfish (Siganus sutor), marine-acclimatized Nile tilapia, mud crab …

Keys To The Families Of Vascular Plants In Northwestern California, James P. Smith Jr, John O. Sawyer Jr

Botanical Studies

No abstract provided.

A Checklist Of Vascular Plants Endemic To California, James P. Smith Jr

Botanical Studies

No abstract provided.

An Annotated List Of The Native And Naturalized Grasses Of Hawaii, James P. Smith Jr

Botanical Studies

No abstract provided.

The Grasses Of Oklahoma, James P. Smith Jr

Botanical Studies

No abstract provided.

Poisonous And Mechanically Injurious Grasses, James P. Smith Jr

Botanical Studies

No abstract provided.

Resource Assessment Report No. 10: Southern Nearshore And Estuarine Scalefish Resource: Sandy Sprat (Whitebait) 2026 Assessment, Daniel E. Yeoh, Brett Crisafulli, Rubie Evans-Powell, Sybrand A. Hesp

Resource Assessment Reports

Sandy sprat Hyperlophus vittatus (‘whitebait’) is a small-bodied clupeid which occurs in temperate nearshore marine and estuarine waters throughout southern Australia. In Western Australia, this species is almost exclusively caught by the commercial sector on the lower west coast, between Perth and Geographe Bay, where it is considered to comprise a single biological stock. Since 2010, sandy sprat has primarily been caught by the South West Beach Net Fishery (SWBN) in the Bunbury region. This is a shore-based fishery which utilises beach seine nets to target a variety of finfish species in shallow nearshore waters.

Commercial catch is monitored and …

Expanding The Global Diversity Of From Deep-Sea Hydrothermal Vents, Anna-Louise Reysenbach, Emily St John, Ryan Catchpole

Biology Faculty Publications and Presentations

The archaeal symbiotic have been isolated with their hosts from a shallow hot marine vent off Iceland and from terrestrial hot springs in Yellowstone National Park and Japan. They have highly reduced genomes and rely on their archaeal hosts for most of their metabolic needs. Here, to provide further insights into the ecology and evolution of this order, we greatly expand their phylogenomic distribution using metagenome-assembled genomes from deep-sea hydrothermal vents in the Atlantic, Pacific and Indian Oceans, and the Gulf of California. We show that at least 11 novel genus-level lineages occur at deep-sea vents. We conservatively propose two …

A Geothermal Amoeba Sets A New Upper Temperature Limit For Eukaryotes, H. Beryl Rappaport, Natalie A. Petek-Seoane, Tomas Tyml, Jessica K. Niblo, Felix Mikus, Naomi E. Gilbert, Kurt Labutti, Godwin Ani, Ethan Macvicar, Rachel M. Shepherd, Ignacio De La Higuera, Samuel J. Lord, Gautam Dey, Kenneth M. Stedman, Multiple Additional Authors

Biology Faculty Publications and Presentations

The study of temperature limits has transformed our understanding of life’s boundaries but has focused on bacteria and archaea. For decades after their discovery, no eukaryote was shown to replicate above 60◦C. We isolated a geothermal amoeba, Incendiamoeba cascadensis, that divides at 63◦C and is motile up to 64◦C. We identified an enrichment of genes related to proteostasis and environmental sensing relative to mesophilic amoebae. Comparative RNA sequencing of I. cascadensis revealed upregulation of pathways related to proteostasis, DNA repair, and membrane trafficking at high temperatures. Predicted proteins of I. cascadensis have distinct biophysical properties, including enrichment of positively charged …

Aleurone Layer Multi-Omics Reveals Constitutive Enzyme-Inhibitor Imbalance In Lma-Contrasting Wheat Cultivars, Utpal Bose, Angéla Juhász, Nicolas Daneri-Castro, Shoko Okada, James A. Broadbent, Keren Byrne, Sally Stockwell, Ronald Yu, Jean-Philippe Ral, Michelle L. Colgrave

Research outputs 2022 to 2026

Late maturity amylase (LMA) is a genetic defect in wheat causing premature accumulation of high-pI alpha-amylase isoforms in the aleurone during grain development, which reduces falling number, resulting in flour downgrading and price penalties. Yet, the aleurone layer proteome and metabolome remain poorly characterised across LMA-contrasting cultivars. We measured the proteome and central carbon metabolome of aleurone from three wheat cultivars differing in LMA-phenotype: Seri (susceptible), Kennedy (intermediate), and Hartog (resistant) – under abscisic acid (ABA), abscisic acid plus gibberellic acid (GA), or untreated conditions. Cultivar identity explained 65.7% of proteome variance, exceeding hormone treatment effects (13.1%), with no significant …

Genomic Vulnerability Of A Threatened Possum In A Biodiversity And Climate Change Hotspot, Grace I. Marsh, Sean James Buckley, Daniel J. White, Adrian F. Wayne, Bryony J. Palmer, Nicola J. Mitchell

Research outputs 2022 to 2026

Spatial variation in the magnitude and pace of climate change impacts means some species will be more affected than others. This includes those occurring within global biodiversity hotspots, regions with exceptional concentrations of endemic species that have often been shaped by long-term climatic stability. Disproportionate levels of human-induced pressure in these areas are threatening much of the biodiversity values that make these biodiversity hotspots exceptional. Southwest Western Australia is a highly fragmented temperate biodiversity hotspot experiencing rapid climate change and supporting many species of threatened mammals. One Critically Endangered arboreal folivore, the western ringtail possum (ngwayir; Pseudocheirus occidentalis), has contracted …

Structural Attributes Of Dominant Seagrass Species Modulate Invertebrate Assemblages Within The Shark Bay World Heritage Area, Inês Leal, Daniel Gorman, Lauren Mukheibir, Keisha Desmond, Simone Strydom

Research outputs 2022 to 2026

The structural complexity of seagrass meadows plays a central role in shaping the diversity and composition of associated invertebrate assemblages. In the Shark Bay World Heritage Area of Western Australia, the dominant species Amphibolis antarctica and Posidonia australis differ markedly in their above- and below-ground morphology, yet the invertebrate assemblages they support remain poorly characterised. This study provides the first contemporary assessment of these habitat–invertebrate relationships, a timely contribution given the region’s increasing exposure to frequent and extreme climatic events. We identified 13,124 invertebrates from 7 phyla, 16 classes and 55 orders/families and highlight marked differences between epifaunal assemblage structure …

Grains, Seeds And Hay Industry Funding Scheme: 2026-29 Strategic Plan, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity published reports

Industry Funding Schemes (IFS) are a powerful effort fuelled by industry support and steered by industry stakeholders. The Grains, Seeds and Hay IFS addresses pest and disease threats that pose a high risk to profitability or production into the grains, seed and hay industry in Western Australia.

The Grains, Seed and Hay IFS is managed by an Industry Management Committee, composed of dedicated producers and growers. As a crucial link between industry and government, our IFS collaborates closely with the Department of Primary Industries and Regional Development (DPIRD) who manage the BAM regulation list and deliver impactful programs.

Key Insights Summary: Improving Local And Coordinated Management Of Stable Fly In Western Australia, Biosecurity Council Of Western Australia

Biosecurity published reports

This Biosecurity Council of Western Australia (Council) Key Insights Summary outlines the scope of advice requested from the Minister for Agriculture and Food the Hon Jackie Jarvis MLC. The report presents the themes identified through stakeholder consultation, and Council’s key observations and findings.

Implementation Of The Problem-Based Learning Model On The Topic Of The Immune System To Enhance The Critical Thinking Skills Of Grade Xi B Students At Sman 1 Tojo, Nani Sofyanti, Sutrisnawati Sutrisnawati, Vita Indri Febriani, Mohammad Jamhari, Bustamin Bustamin, Raya Agni

Jurnal Pendidikan Sains

Critical-thinking skills are essential competencies for students in 21st-century learning. Preliminary classroom observations in Class XI B at SMAN 1 Tojo indicated that instruction remained predominantly teacher-centered and provided limited opportunities for students to engage in activities involving interpretation, analysis, evaluation, and inference. This study aimed to improve students’ critical-thinking skills through the implementation of Problem-Based Learning (PBL) on the immune system topic. The study employed a Classroom Action Research (CAR) design conducted over two cycles, involving 28 students in Class XI B. Data were collected using a teacher activity observation sheet and critical-thinking skills tests assessing four indicators: interpretation, …

Junior High School Students’ Understanding Of Pathogenic Microbes In The School Environment: A Cross-Grade Descriptive Study At Smp Alkhairaat 1 Palu, Feren Febrianti, I Nengah Kundera, Yulia Windarsih, Mohammad Jamhari, Mursito S. Bialangi, Abdul Ashari

Jurnal Pendidikan Sains

This study aimed to describe students’ understanding of pathogenic microbes and compare descriptive comprehension profiles across Grades VII, VIII, and IX at SMP Alkhairaat 1 Palu. A quantitative descriptive approach was employed involving 49 students selected through purposive sampling. Data were collected using an essay test as the primary instrument, supported by semi-structured interviews and observations of the school environment. The essay test assessed three indicators: conceptual knowledge of pathogenic microbes, understanding of disease transmission mechanisms, and understanding of clean and healthy practices for preventing the transmission of pathogenic microbes. Test data were analyzed descriptively using mean percentage scores, while …

The Ability Of Biology Teachers Of State Madrasah Aliyah In Palu City In Developing Teaching Modules In Merdeka Curriculum, Ulya Afifa, Gamar B. N Shamdas, Syech Zainal, Bustamin Bustamin, Raya Agni, Rafiqa Rafiqa

Jurnal Pendidikan Sains

Teachers’ ability to develop teaching modules is essential for implementing the Merdeka Curriculum because it enables curriculum expectations to be translated into flexible and context-responsive learning. This study aimed to describe Biology teachers’ ability to develop teaching modules at State Islamic Senior High Schools (Madrasah Aliyah Negeri [MAN]) in Palu City and to identify the factors supporting or constraining this ability. A descriptive qualitative study was conducted with seven Biology teachers from MAN 1 Palu, MAN 2 Palu, and MAN Insan Cendekia Palu during February–March 2026. Data were collected through questionnaires, interviews, documentation, and analysis of teaching modules using …

Obsessive-Compulsive Subtraits And Self-Agency, Jacob Nelson, Cody Barton, Carissa Phillipi Phd

Undergraduate Research Symposium

Obsessive-Compulsive Disorder (OCD) is categorized by persistent, unwanted thoughts, called obsessions. and repetitive behaviors, called compulsions. The Obsessive-Compulsive Inventory-Revised (OCI-R) is a valid measure of OCD, and breaks the condition into six subtraits: Checking, Hoarding, Obsessing, Ordering, Neutralizing, & Washing. Prior research has suggested that one’s sense of agency, measured through the Sense of Agency Scale (SoAS), is lower in those with higher overall OCI-R scores compared to those with lower scores and controls. Additionally, sub-clinical checking has been negatively correlated with sense of agency, and sub-clinical hoarding and ordering have been positively correlated with sense of agency. However, there …

Phenotypic Variation Between Surface And Cave-Adapted Poeciliids And Its Effect On Metabolism, Karch Knipp, Michael Tobler, Soren Johnson

Undergraduate Research Symposium

Cave-adapted organisms often exhibit pronounced morphological changes relative to their surface counterparts, a phenomenon known as troglomorphy. In Poecilia mexicana (Atlantic molly), these differences include variation in coloration between surface and cave populations. Troglobitic organisms also typically exhibit reduced metabolic rates, likely as an adaptation to environments with low primary productivity. This makes P. mexicana an ideal system for investigating the evolution of metabolic traits. In this study, we leveraged variation in coloration among cave-dwelling mollies to examine potential associations with resting metabolic rate (RMR). Coloration was quantified using PCR values, and individuals were categorized as “yellow” or “non-yellow.” We …

The Impact Of Caffeine On Bumble Bee Hunger, Hallie Chapman, Becky Hansis-O'Neill, Aimee Dunlap Phd

Undergraduate Research Symposium

Bumble bees (Bombus impatiens) are crucial pollinators, responsible for pollinating multiple native plants and agricultural crops. Caffeine, which is classified as a stimulant, is present in some of these plant species at varying levels. Alterations in bumble bee cognition, including motivation, learning, and hunger, have been associated with caffeine intake. This study explored the impacts of caffeine on the bumble bee behavior on a biological level. While previous research has examined caffeine’s effects on cognition and learning, fewer studies have investigated its effects on hunger at the level of individual bees. Bumble bees, identified with numerically labeled tags, …

Tarantulas Can Use Black And White Cues In A Discrimination Learning Task, Jordan Kolinski, Becky Hansis O'Neill, Amiee Dunlap

Undergraduate Research Symposium

Animals use vision to perceive light, shapes, colors, and movement. Many animals that have poor vision are understudied. The purpose of this experiment was to study color vision in tarantulas (Brachypelma hamorii). Researchers have found genes associated with color vision tarantulas, but no behavioral experiments have been done on this topic. Previous research has also shown that tarantulas can see polarized light. In this experiment, we wanted to know if tarantulas could use visual cues to move away from a noxious stimulus - vibration. There were twelve tarantulas being tested in this experiment for between twelve and fifteen …

Relationship Between Morphological And Behavioral Laterality In Astyanax Mexicanus, Allison Lendman, Michael Tobler, Erik Johnson

Undergraduate Research Symposium

Populations within the Astyanax genus have experienced extreme differences in environment, leading to distinct morphological adaptations. The cave populations of these fish are eyeless and have acquired fixed, cranial asymmetries. We explored a possible relationship between this physical asymmetry and behavioral laterality. We tested 28 adult fish, 14 male and 14 female, from the Pachón cave in controlled behavioral trials. We found that both sexes demonstrated behavioral laterality, observed as a consistent left-turn bias in these trials. This supports the hypothesis that these populations display behavioral laterality that is correlated to their physical asymmetries. Ongoing research comparing behavioral patterns in …

Under The Surface: Human Disturbance Reduces Species Richness In Glade Microhabitats, Maddie Smith, Becky Hansis-O'Neill, Aimee Dunlap Phd

Undergraduate Research Symposium

Human disturbance can alter microhabitats in ways that affect biodiversity, especially in sensitive ecosystems like glades where many animals rely on rocks for thermoregulation and refuge. This study examined how rock displacement by human activity influences species richness and community composition in glade habitats at Shaw Nature Reserve and Victoria Glades Conservation Area. We hypothesized that disturbed rocks would be less suitable for wildlife and would support fewer species. From September to November 2025, about 30 rocks per site were pseudo-randomly selected and monitored. Each rock was classified as displaced or nondisplaced, and all organisms found beneath them were recorded. …

Enantioselectivity Of The Photochemical Continuous-Flow Isomerization Of Humulones, Gregory M. Giovine, Trevor Smith, Bruce Hamper

Undergraduate Research Symposium

Humulones, the primary natural product present in the historically significant hop flower, represent a largely unexplored candidate for structure-based pharmaceutical design.  Showing promising biological activity as an anti-bacterial and anti-inflammatory agent, humulones are of interest both for their bioactive properties and for their long-established tolerability and natural abundance.  Humulones undergo a characteristic isomerization reaction, where the six-membered substituted phloroglucinol ring contracts to a five-membered ring isohumulone, under a variety of conditions, including those enabled by brewing conditions (thermal, metal-catalyzed) and by exposure to UV light.  Optimization of the photocatalyzed isomerization of n-humulone to n-isohumulone in flow conditions resulted in a …

Wasps Survive Tornadoes, But It Impacts Nest Growth, Natalie Cummins, Sara E. Miller

Undergraduate Research Symposium

As the climate becomes more variable, extreme weather events become more common. Last May, St. Louis was hit by an EF-3 tornado. Many areas of the city suffered 90-150 mph winds and severe property damage. We knew there were established paper wasp populations in the affected areas, and so we took this opportunity to monitor emerging nests throughout the summer and fall in both tornado-affected and non-affected areas to observe any possible effect on their nest growth rate and overall size. There is currently very little literature investigating the response of insects to natural disturbances, like tornadoes. Additionally, most studies …

Building Genetic And Culturing Tools For The Understudied Soil Bacterium E. Flagellatus, Aaron Butler, Brenda Pratte, Lon Chubiz

Undergraduate Research Symposium

Soil bacteria play essential roles in nutrient cycling, yet many abundant groups remain poorly characterized due to challenges in cultivation and genetic manipulation. One such organism is Edaphobacter flagellatus, a member of the Acidobacteriota frequently detected in soil environments but lacking well-developed experimental tools. To address this limitation, our laboratory has generated a genome-wide mutant library using the Tn5 transposon, enabling random disruption of genes across the population.

This project aims to establish culture conditions necessary to support the use of this library for functional genomic studies. In particular, defined minimal media can impose selective pressures that reveal …

Winter Contents Of Tree Cavities In Oak Woodland Habitats, Lucy V. Roth, Addy Yoder, Jalene M. Lamontagne Phd

Undergraduate Research Symposium

Woodpeckers create cavities in dead and decaying trees and branches of live trees, many of which are used by a range of other animals, and are thus called “ecosystem engineers”. A species of conservation concern in the midwest is the red-headed woodpecker (RHWO). RHWO in the upper midwest are facultative migrators meaning some individuals stay in their territories over winter and others migrate south. Most tree-cavity research is done during the breeding season, leading to a knowledge gap of their use in the non-breeding season; therefore, studying them in winter could help us understand their ecological impact. RHWO require food …