Life Sciences Commons^™

Neuropsychological Research On The Neurosurgical Treatment Of Cerebrovascular Disease, James Ausman, Mark W. Shatz

Henry Ford Hospital Medical Journal

No abstract provided.

Carotid Artery Disease, Carotid Endarterectomy, And Behavior: A Critical Appraisal, Mark P. Kelly

Henry Ford Hospital Medical Journal

We reviewed the recent literature on the relationship between carotid artery disease, carotid endarterectomy, and behavior. The methodological adequacy of each study and the complexities involved in interpreting behavioral changes in patients with carotid disease are emphasized. Experimental design issues qualify conclusions in all studies. The weight of the evidence suggests that carotid artery disease may result in cognitive impairment, and that carotid endarterectomy is followed by psychometrically determined cognitive improvement in some patients. Although characteristics of the subgroup of patients most likely to improve have been identified in preliminary investigations, the clinical significance of such improvement has not been …

Methodological Issues In Studying Treatment Effects In Patients With Cerebrovascular Disease, Mark W. Shatz

Henry Ford Hospital Medical Journal

Evaluation of the neuropsychological effects of surgical treatment on cerebrovascular disease is beset by numerous methodological difficulties. These include problems specific to this patient population as well as others inherent in all retrospective studies. Five such problems are described: 1) nonrandomized subject selection; 2) dropout from follow-up; 3) natural history of cerebrovascular disease; 4) effects of hospitalization; and 5) the role of practice effects. This paper examines these methodological problems for their impact on our knowledge and proposes alternative research directions to address their shortcomings.

Microsurgical Techniques In Cerebral Revascularization, James I. Ausman, Fernando G. Diaz, R. A. De Los Reyes, Carl Shrontz, Jeffrey Pearce, Manuel Dujovny

Henry Ford Hospital Medical Journal

The surgical management of patients with cerebrovascular disease is reviewed. Our approach to the management of extracranial cerebral vasculature is discussed first, and increasingly more complex areas are then presented. Our discussion reviews the applications of carotid endarterectomy, extracranial-intracranial bypass procedures, and vertebral extracranial reconstruction.

Neuropsychological Evaluation Of The Results Of Surgical Treatment Of Cerebrovascular Disease, Melvin L. Schwartz

Henry Ford Hospital Medical Journal

No abstract provided.

The Effects Of Cerebrovascular Surgery On Behavior: What Has Been Demonstrated?, Laurence M. Binder

Henry Ford Hospital Medical Journal

We studied the effect of the superficial temporal artery to middle cerebral artery bypass (STA-MCA) procedure on neuropsychological function. Nineteen patients with cerebrovascular disease of the anterior carotid circulation (12 on surgical and seven on medical therapy) received an extensive battery of neuropsychological tests; the average test-retest interval was eight weeks. Both groups improved on some measures, and no patients deteriorated. There was no evidence of greater improvement by the surgical group. The results are compatible with a spontaneous remission/practice effect interpretation. A review of the carotid endarterectomy and STA-MCA bypass literature suggests that the null hypothesis of no effect …

Violence, James R. Creps

Henry Ford Hospital Medical Journal

No abstract provided.

A Radiologic Method Of Assessment Of Bone And Joint Destruction In Rheumatoid Arthritis, Gilbert B. Bluhm, David W. Smith, Walter M. Mikulashek

Henry Ford Hospital Medical Journal

We employed radiographic analysis and a numerical scoring system to evaluate bone and joint destruction in 39 patients who received aspirin and nonsteroidal, antiinflammatory drugs or benoxaprofen therapy over a continuous study period of 36 months (mean). Our purpose was to compare the radiological changes in these patients over two observation intervals and to test the reproducibility of the scoring system. Our modified rating system has sufficient intra-rater reliability to provide a statistically adequate, reproducible method for evaluating bone and joint destruction in rheumatoid arthritis.

Manipulation Of External Tachodynamometer By The Patient: Case Report, Chang Y. Lee, Michael P. H. Lau

Henry Ford Hospital Medical Journal

External tachodynamometer has frequently been used to evaluate premature labor. In three cases, the patient was apparently able to record uterine contraction-like curves by means of abdominal pressure. In two of these cases, the patient was evidently using this manipulation to gain attention and support from her husband and/or family members. In the third case, described in this paper, because false curves were recorded, an emergency Caesarean section was performed under the impression that abruptio placenta had occurred.

Synchronous Bilateral Seminomas And Teratoma, Harry J. Bonnell

Henry Ford Hospital Medical Journal

The simultaneous occurrence of seminomas is extremely rare. Only 23 cases have previously been reported. One case has been reported of extrascrotal mature teratoma following primary pure seminoma of the testis. We describe a 47-year-old patient who presented with synchronous bilateral seminomas and a left-sided, mature teratoma of the testis.

Posttraumatic Hernia Of The Bladder, Joseph L. Ponka, Farouck N. Obeid

Henry Ford Hospital Medical Journal

Fractures of the pelvis occur commonly in patients who are involved in high speed vehicle accidents or who fall from a substantial height. Fortunately, with improved surgical management, these patients usually recover not only from the pelvic fractures but from associated visceral injuries as well. Some survivors of pelvic fractures subsequently develop unusual hernias. We report the case of a man who developed hernia of the urinary bladder following pelvic fracture. Two previous operations had failed to eliminate his hernia. We describe the technique of repair used successfully in this case and review similar reported cases. Surgeons who care for …

Editorials

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Role Of Erythropoietin In The Anemia Of Chronic Renal Failure, N. Kevin Krane

Henry Ford Hospital Medical Journal

The major factors responsible for the anemia of chronic renal failure are decreased erythropoietin (Ep) production, the presence of inhibitors of erythropoiesis, blood loss, and hemolysis. Ep, which is produced in the kidney, probably exerts its effect on the colony-forming units of the erythrocyte. Ep levels fall with worsening renal function (creatinine clearances in the range of 2-40 ml/min). but they rise to their highest levels in the immediate predialysis period, probably due to severe ischemia of both renal and extrarenal production sites. When patients are begun on hemodialysis, Ep levels fall, and the hematocrit rises. Erythropoietin therapy in the …

Identification Of Four Complementary Rna Species In Akabane Virus-Infected Cells, Asit K. Pattnaik, G. Abraham

School of Veterinary and Biomedical Sciences: Faculty Publications

The analysis of RNA extracted from purified Akabane virus demonstrated the presence of three size classes of single-stranded RNAs with sedimentation coefficients of 31S (large, L), 26S (medium, M), and 13S (small, S). Molecular weights of these RNA species were estimated to be 2.15 x 10⁶,1.5 X 10⁶, and 0.48 x 10⁶ for the L, M, and S RNAs, respectively. Hybridization analysis involving viral genomic RNA and RNA from virus-infected cells resulted in the identification of four virus-specific cRNA species in infected cells. These cRNAs were found to be nonpolyadenylated by their inability to bind …

The Zinc Status Of Pregnant Vegetarian Women, Michelle J. Abu-Assal

Loma Linda University Electronic Theses, Dissertations & Projects

The zinc status of twelve lacto-ovo-vegetariah pregnant women and seventeen non-vegetarian pregnant women was evaluated. Zinc intakes were calculated from three-day dietary records and twenty-four hour dietary histories. Plasma zinc levels were drawn during the last trimester of pregnancy and approximately ten weeks postpartum. Gestational age at birth, birthweight, and APGAR scores of the infants born were obtained from the medical charts. Dietary zinc intakes for the vegetarians (10.5 ± 4.0 mg) did not differ significantly from the intakes of the non-vegetarians (10.9 ± 3.0 mg). The vegetarian last trimester plasma zinc levels (47.9 ± 12.4 mcg/dl) and postpartum plasma …

Full Issue, Vol. 7

Great Basin Naturalist Memoirs

No abstract provided.

End Matter, Vol. 7

Great Basin Naturalist Memoirs

No abstract provided.

Front Matter, Vol. 7

Great Basin Naturalist Memoirs

No abstract provided.

Audiological Characteristics Of The Monge Family Of Costa Rica, Christine Moulton

Dissertations and Theses

The audiological characteristics of the Monge family of Costa Rica were investigated in a sample of fifty-two affected members and twelve unaffected members. Through laboratory analysis by staff personnel from the University of Costa Rica and audiological test results obtained in the present investigation, it was concluded that affected Monge members demonstrate a slowly progressive low frequency sensorineural hearing loss of autosomal dominant transmission. The initial site of lesion appears to be the apical portion of the cochlea, with significant onset occurring during early childhood following normal speech and language acquisition. The rate at which the hearing loss progresses and …

Recombinant Immune Interferon Increases Immunoglobulin G Fc Receptors On Cultured Human Mononuclear Phagocytes, Paul M. Guyre, Peter M. Morganelli, Renee Miller

Dartmouth Scholarship

Although recent studies suggest that interferons can increase the number of IgG Fc receptor (FcR gamma) sites on mouse macrophages, direct assessment of similar effects on human mononuclear phagocytes is lacking. We therefore measured the specific binding of 125I- and fluorescein-labeled IgG1 to human monocytes and leukemic cell lines after culture in vitro with highly purified human interferons. We report that natural and recombinant human gamma-interferon causes a dramatic (nearly 10-fold) increase in the number of FcR gamma on normal human monocytes and on the human cell lines HL-60 and U-937. Alpha and beta-interferons cause a modest but significant increase …

Santa Clara Magazine, Volume 25 Number 8, Spring 1983, Santa Clara University

Santa Clara Magazine

2 - FIRST FRIEND by Robert Meyers. Nevada Senator Paul Laxalt talks about his special relationship with the President of the United States.

6 - A CONVERSATION WITH BROTHER ROGER by Patrick Samway, S.J. An interview with the founder of a remarkable ecumenical community that has become a source of inspiration for Christians everywhere.

11 - JESUIT CHAPLAINS IN WORLD WAR II by Donald F. Crosby, S.J. Chronicling the involvement of 273 Sons of Loyola who marched off as chaplains in World War II.

15 - PSYCHOLOGY AT THE STOCK EXCHANGE by Jerry Kroth. Can psychology provide us with an …

Issues In Diabetes: 1983, Fred W. Whitehouse

Henry Ford Hospital Medical Journal

No abstract provided.

Experience With Biosynthetic Human Insulin In Diabetes, Davida F. Kruger, Fred W. Whitehouse, Dorothy M. Kahkonen, Jean O. Partamian, J. David Fachnie, José Goldman, David Leach

Henry Ford Hospital Medical Journal

Thirty diabetic patients new to insulin were entered in an open label prospective study of biosynthetic human insulin (BHI). All patients experienced symptomatic control of diabetes attributable to dietary and BHI insulin therapy. Detailed six-month evaluation data were reviewed in 19 patients. A significant drop in fasting plasma glucose and glycosylated hemoglobin was noted at two months, and a further modest decrease occurred at six months. E. coli polypeptide antibodies were unchanged from baseline at six months, indicating that no bacterial protein contamination of BHI occurred. Percent binding of serum antibodies to human insulin measured in 19 patients at baseline …

The Artificial Pancreas Today, James F. Mcmurry Jr.

Henry Ford Hospital Medical Journal

An artificial pancreas is now available in selected centers for clinical use in blood glucose control. With information derived from 24-30 hours of "closed-loop" insulin administration by means of the artificial pancreas, subcutaneous insulin doses may be determined for insulin-dependent diabetic patients. Eleven poorly controlled diabetic patients had their insulin doses reevaluated with the artificial pancreas. Ten of 11 patients showed improved glucose control when their insulin doses were modified by this method.

Current Management Of Pregnancy In The Diabetic: A Team Approach, Seth G. Kivnick, J. David Fachnie, Chang Y. Lee

Henry Ford Hospital Medical Journal

We reviewed details of 89 pregnancies in diabetic women who were delivered from 1980 through 1982. Data are presented on the obstetrical outcome and the level of diabetic control in patients with White classifications of B through R. Although the mean blood glucose levels of all groups failed to meet the criteria for ideal metabolic control (fasting less than 105 mg/dl, postprandial less than 120 mg/dl), the perinatal mortality rate of 4% compared favorably with reports from other centers. Fifty-six percent of our patients were delivered at 37 weeks gestation or later. The primary Caesarean section rate was 37%, and …

Plasma Lipid Abnormalities In Diabetes Mellitus: Observations On Hdl Cholesterol And Recommendations For The Management Of Lipid Abnormalities, Dorothy Kahkonen

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Recommendations For Care Of The Asymptomatic Patient, James D. Bridges, Thomas Killip, N. Kevin Krane, David B. Macdougall, Carlos F. Petrozzi, Michael E. Somand, Susan Steigerwalt

Henry Ford Hospital Medical Journal

We present a set of reasonable guidelines for the care of healthy, asymptomatic individuals based upon recommendations prepared by an Internal Medicine review committee of Henry Ford Hospital. There recommendations have four goals: to prevent disease, to detect disease in an asymptomatic and potentially curable state, to enhance the patient's quality of life, and to help physicians teach patients good health habits. Recommendations are made for infectious diseases, cancer, metabolic diseases, neurosensory conditions like visual and hearing loss, and general health habits. Some recommendations are at variance with those of well recognized authorities and should be viewed only as a …

The Exclusion Of Restrictive Lung Disease By Spirometric Criteria In Patients With A Reduced Forced Vital Capacity, Michael S. Eichenhorn, John Popovich Jr., Richard K. Beauchamp, John Armstrong, Joseph C. Ward

Henry Ford Hospital Medical Journal

Reductions in forced vital capacity (EVC) as determined by spirometry may result from restrictive or obstructive disease, either alone or in combination. Restrictive disease is implied when measures of forced expiratory flow are relatively maintained, and obstructive disease is present when flow measurements are disproportionately reduced. In the presence of air flow obstruction, the possibility of concomitant restrictive disease contributing to the reduction in FVC is difficult to assess from spirometry alone. Static lung volumes are usually necessary to establish this diagnosis. We evaluated the FEV1/EVC%o obtained at spirometry compared to its predicted normal value. We found it to be …