Life Sciences Commons^™

Operationally Ready Vs Gym Ready: Training For The Real Demands Of Tactical Work, Ben Jacobs

Tactical & Occupational Performance Conference

Tactical organizations are increasingly recognizing that readiness extends beyond fitness alone. Structured performance systems that integrate training, recovery, nutrition, and fatigue management can help departments improve resilience, reduce injuries, and sustain operational capability over an entire career.

Session's revolve around the concept of Tactical Readiness Architecture, a systems-based framework designed to help departments build structured, sustainable performance support for their personnel. Rather than focusing solely on workouts or individual habits, Tactical Readiness Architecture integrates training, recovery, nutrition, fatigue management, and data-informed monitoring into a cohesive readiness model.

Preoperative Low-Intensity Blood Flow Restriction Training Does Not Improve Quadriceps Strength Or Hypertrophy After Anterior Cruciate Ligament Reconstruction, Daniel Mcgurren, Kaycee Glattke, Molly Klanderman, Jedediah Lee, Anikar Chhabra, Arthur De Luigi

Journal for Sports Neuroscience

Objectives: To investigate the efficacy of a preoperative low-intensity blood flow restriction (LI-BFR) training intervention for patients undergoing anterior cruciate ligament reconstruction (ACLR).

Design: Pilot study

Methods: Twenty-eight patients undergoing primary ACLR participated in either a LI-BFR training or sham intervention at a rate of 2 sessions per week for 2 weeks before surgery. Quadriceps strength and cross-sectional area were measured via handheld dynamometry and leg press test before and after the intervention before surgery and at 5 different time points after surgery, through 24 weeks after surgery.

Results: Adjusting for sex, time, and strength/hypertrophy at baseline, there were no …

Cardiovascular Disease Subtypes And Alzheimer's Disease: Phenotypic And Genetic Associations In The Uk Biobank And All Of Us Research Program, Aili Toyli, Chen Zhao, Kuan Jui Su, Hui Shen, Hong Wen Deng, Qing Hui Chen, Qiuying Sha, Weihua Zhou

Michigan Tech Publications

BACKGROUND: Cardiovascular disease (CVD) and Alzheimer's disease (AD) are major public health concerns that share overlapping risk factors and potential mechanistic pathways. Although vascular contributions to cognitive decline are well documented, the specific relationships between AD and different CVD subtypes remain poorly understood. METHODS: In this cross-sectional study, we examined associations between AD and 11 CVD subtypes using logistic regression models in 2 large biobanks: the UK Biobank (n=502 133) and the All of Us Research Program (n=287 011). Models were adjusted for demographic, lifestyle, and clinical covariates. We also explored genetic overlap between AD and CVD traits through proximity-based …

Neuromuscular Responses During Vigorous Intensity Heart Rate-Clamp Cycling Exercise, Clara J. Mitchinson, Pasquale J. Succi, Brian Benitez, Djadmann Gustave, Minyoung Kwak, Erik Snell, Haley C. Bergstrom

Journal for Sports Neuroscience

Introduction: Electromyography (EMG) and mechanomyography (MMG) provide non-invasive assessments of neuromuscular function and fatigue during dynamic exercise. This study examined neuromuscular fatigue and cycling performance through changes in power output (PO), total work (TW), EMG and MMG, amplitude (AMP) and mean power frequency (MPF) during three, heart rate (HR)-Clamp trials in the vigorous range (77-95% HR_max). Methods: Ten men (mean±SD, 25.9±5.0yr, 74.9±15.0kg, HR_max=178±12b×min^-1) performed a cycle ergometer graded exercise test, followed by three separate HR-Clamp trials at 77%HR_max (HR_L, time to exhaustion [T_Lim]=58.5±4.6 min, range=45.3-60.0min), 86%HR_max (HR_{M …}

Intramuscular Nad⁺ Therapy And Neuroenergetic Symptom Modulation: An Exploratory Retrospective Human Pilot Study, Zachary J. Dickey Do, Kirtan Patel Bs, Randy Aldret Edd, Cscs, Atc, Navneet Sharma Md, Glenn Goodwin Do

Journal for Sports Neuroscience

Abstract

Background: Nicotinamide adenine dinucleotide (NAD⁺) is a central regulator of neuronal energy metabolism, mitochondrial function, and axonal integrity. Following mild traumatic brain injury (mTBI) and repetitive subconcussive exposure, neurons undergo a neurometabolic crisis characterized by impaired oxidative phosphorylation, increased ATP demand, and depletion of intracellular NAD⁺ pools. Pre clinical models demonstrate that NAD⁺ depletion contributes to central energy dysregulation, cognitive dysfunction, and axonal and neuronal degeneration through disruption of NAD⁺-dependent pathways including SIRT1-mediated mitochondrial resilience, PARP1-driven NAD⁺ consumption, and SARM1-associated axonal breakdown. Despite growing preclinical evidence supporting NAD⁺based neuroprotection, human clinical data remains absent.

Methods: A real-world clinical pilot …

Shared Premotor Resources Underlie Dual-Task Interference Between Speech And Balance, Weina Lu, Sasha Lifton Lewis, Zoey Wire, Ingo Helmich

Exercise and Sport Studies: Faculty Publications

Humans frequently speak while standing, potentially engaging overlapping motor-cognitive resources. Dual-task paradigms with increased motor-cognitive demands reliably impair postural control, presumably due to competition for shared neural resources. The premotor cortex is critically involved in balance stabilization and in resolving competing motor plans and is also engaged during processing of action-related language. We therefore hypothesized that a central processing bottleneck emerges in the PMC when speaking and controlling posture simultaneously. Forty-one right-handed healthy adults (25 female, 16 male) maintained an upright stance while either verbally describing or mentally imagining navigation through a visually presented maze from an egocentric or allocentric …

Severity Of Deficit In Skeletal Muscle Lipid Metabolism Invokes Unique Adaptive Responses In Dietary Lipid Intake And Absorption, Victoria Datta

Masters Theses

Skeletal muscle plays a central role in whole-body lipid metabolism through mitochondrial and peroxisomal fatty acid oxidation (FAO). When skeletal muscle lipid metabolism is impaired, whole-body adaptations occur to maintain metabolic homeostasis. We hypothesized that limiting skeletal muscle lipid metabolism through mitochondria and/or peroxisomes would trigger adaptive responses to reduce dietary lipid intake and/or absorption with the most robust changes coinciding with deficit severity. Mice were generated with skeletal muscle-specific deletion of 1) carnitine palmitoyltransferase 1b (Cpt1bM-/-) to limit mitochondrial FAO, 2) peroxin 5 (Pex5M-/-) to impair peroxisomal FAO, and 3) both Cpt1b and Pex5 (DKO). Results were compared to …

University Of Nebraska At Omaha Division Of Biomechanics And Research Development Annual Report 2023-2025, Uno Biomechanics

Biomechanics Annual Report

This report contains:

A letter from the Director: Dr. Nick Stergiou

Highlights articles

Center for Cardiovascular Research in Biomechanics (CRiB) articles

The Center for Research in Human Movement Variability (MOVCENTR) articles

People of UNO Biomechanics

Student Centered articles

Education Initiative articles

Working Out Your Self-Image: Strength, Self-Esteem, And Human Flourishing, Kingston K. Christie

Honors Projects

This project integrates empirical research in exercise science with theological anthropology to examine the psychological effects of resistance training and the meaning of strength within a Christian framework of human dignity and flourishing. The empirical component investigated the effects of a four-week progressive resistance training intervention on global self-esteem and physical self-concept among undergraduate university students with moderate-to-low baseline self-esteem. Eleven participants (N = 11; 20.15 ± 1.52 yrs) completed the Rosenberg Self-Esteem Scale (RSES) and Physical Self-Description Questionnaire Short Form (PSDQ-S) before and after the intervention, with muscular strength assessed via submaximal testing across the squat, bench press, deadlift, …

Limits Of Post-Activation Performance Enhancement: Asymmetry Persists Despite Performance Gains, Talia Thompson, Monique Mokha

Journal for Sports Neuroscience

Post-activation performance enhancement (PAPE) protocols are commonly used to improve power, yet their influence on inter-limb force symmetry remains unclear. This study examined the effects of a PAPE protocol on inter- and intra-session symmetry and performance during a countermovement (CMJ. Ten American football players preparing for the National Football League’s draft completed a complex PAPE protocol consisting of two baseline CMJ trials on dual uniaxial force plates, followed by three sets of maximum effort lower-body lifts (e.g., split squats) alternated with two CMJ trials. Jump height (JH), reactive strength index modified (RSImod), and asymmetry indices for concentric impulse (CIA), eccentric …

Ankle Dorsiflexion Is A Primary Influence On Single Limb Landing Stability Regardless Of Menstrual Cycle Chase, Olivia Matrulli

Honors Theses

Context: Hormonal fluctuations associated with the menstrual cycle contribute to modifications in joint laxity. Conflicting evidence supports increased ligamentous injury risk and altered postural control in response to these cyclic changes. Objective: To quantify changes in passive joint flexibility and dynamic postural control across the menses and luteal phases of the menstrual cycle. Design: Repeated measures. Setting: Research laboratory. Participants: Thirteen healthy females (20 [1] y, 1.62 [0.06] m, 67.42 [11.75] kg) with a regular menstrual cycle over the last twelve months volunteered. Interventions: Participants performed five static flexibility tests and three single-leg drop landings onto a force plate with …

The Marathon Without Running: Experiencing A Runner's Sensorial Journey, Harin Kim

Masters Theses

The marathon is defined not by motion alone, but by the changing conditions a body moves through—and remains within—over time. Breath, cadence, heat, sound, crowd compression and attention fluctuate, producing phases that structure the race from within. These interior states are difficult to access by spectators from the sidelines, yet they are precisely what shape the runner’s experience.

This thesis begins with a simple but unconventional question: How can an exhibition translate the runner’s physical sensations and emotions into a multidimensional experience for spectators who do not run? Through a sequence of pop-up exhibitions placed along the New York City …

Slouching Towards Inefficiency? The Cardiometabolic And Cognitive Costs Of Poor Posture, Ava Mae Fitzenrider

Honors Projects

Posture affects all of our lives. It is both static and dynamic, adapting continuously to environmental demands. One postural alteration frequently observed in occupational settings is hyperkyphosis, which can be induced by sitting position. During computer use, individuals commonly adopt a slouched posture, which can exacerbate hyperkyphosis, and contribute to dis-ease within the body. Previous research has demonstrated that such postural deviations can negatively affect pulmonary function, as well as other bodily functions. Despite these findings, the effects of acute hyperkyphosis (“slouching”) on cardiometabolic function and cognition remain largely unexplored. Therefore, the purpose of this study was to examine the …

Correlations Between The Army Combat Fitness Test (Aft) Events And The 12-Mile Ruck March, Isabella Huner Cruz

Masters Theses

The Army Fitness Test (AFT) consists of maximum deadlift, hand-release push-ups, sprint-drag-carry, plank, and a 2-mile run and is used by the United States Army to assess a soldier’s ability to meet occupational demands. The AFT is designed to ensure soldier readiness and maintain physical and mental well-being. In addition to the AFT, soldiers are often tasked with a loaded ruck march across various distances. Loaded ruck marches are a frequent occurrence in the Army as a mode of testing, training, and combat. Due to the AFT’s role in predicting soldier task performance, it would be valuable to identify any …

Difference Between Postural Sway, Functional Fitness, And Behavioral Measures In Older Adult Fallers & Non-Fallers, Olivia Maus, Rebecca Brandhorst, Andrea Geisenhof, Kyle Reason

InnovateHER Meeting 2026

BACKGROUND: Falls are among the leading causes of injury, hospitalization, and loss of independence among older adults. There is not enough research to determine how body composition, fitness, and postural sway affect balance.

METHODS: Participants completed surveys measuring behaviors around fall risk, assessment of body composition, postural sway, and functional fitness.

RESULTS: There was a significant difference between OF and ONF on the FES-I (p=0.05; d=-0.41) and the ABC-6 (p=0.008; d=0.57). There was significance on condition three of the mCTSIB (p=0.007; d=-.58), and composite score (p=0.04; d=-0.43).Significance between groups was approached on condition one of the mCTSIB (p=0.06; d=-0.39).

CONCLUSIONS: …

Living With Confidence: The Importance Of Hip Health, Ellisa Louisy, Shannon M. Meyer, Kyle W. Reason

InnovateHER Meeting 2026

The hip joint is essential for weight-bearing movement, providing both mobility and stability as a ball-and-socket joint. Surrounding muscles generate movement and maintain stability during daily activities like walking, standing, and rising from a chair. As the link between the trunk and lower limbs, reduced hip strength or mobility can impair balance and movement efficiency. In women, hormonal changes, especially after menopause, contribute to decreased bone density and muscle mass, increasing the risk of osteoporosis and hip fractures and underscoring the importance of hip health.

Caffeine Perceptions And Reality In High School Gymnasts, Gabrielle Steinkopf

InnovateHER Meeting 2026

From years of observation as a high school gymnast, there is a noted “caffeine culture” among gymnasts at my high school. Since gymnastics is a precision sport with not inconsiderable danger, I wondered what impact caffeine ingestion had on athletes. Athletes were asked to give up caffeine during a series of regular season meets, with reflection questions immediately after each meet to assess the impact caffeine might have had on performance vs the gymnasts’ perception of the effects

Hip Stretching Protocol's Impact On Female Ice Hockey Players, Cienna Clark

InnovateHER Meeting 2026

Women’s ice hockey participation continues to grow as do injury rates among these players. However, female ice hockey players often show different injuries than male players. This is largely due to the lack of checking in women’s hockey, which means the injuries that tend to be seen are more about overuse injuries and less catastrophic injuries. Female injuries also tend to be more in their hips, which begs the question: what would happen if hips were stretched on a regular basis? Would these injuries subside, or at least improve?

The Effect Of Acute Hypoxia Exposure, With Exercise, On Bone Metabolic Biomarkers, Alyssa Bailly

Health, Exercise, and Sports Sciences ETDs

Hypoxic environments, resulting from decreased atmospheric partial pressure of oxygen, reduce oxygen availability in the blood and tissues, leading to a mismatch between supply and demand. This elicits several physiological adaptations and may influence bone metabolism. Although evidence suggests that hypoxia can modulate bone remodeling through hypoxia-inducible pathways, findings remain mixed, with most data derived from chronic hypoxic exposures in animal and cell culture models. Exercise, an essential stimulus for bone health, may exacerbate hypoxic stress; however, the skeletal response to acute hypoxic exposure combined with exercise remains unclear. We propose that intermittent exercise in hypoxia may increase negative markers …

Influence Of The Discipline Of Authentic Movement Practice On Interpersonal Relationships, Joy Ruben Welts

Educational Studies Dissertations

This mixed methods study explored how practicing the Discipline of Authentic Movement impacts relationships. This research was conducted to fill in the gaps around attunement and use of the Discipline of Authentic Movement as an intervention to support healthy relationships. Five self-selected adults met on Saturday afternoons for eight weeks to practice the Discipline of Authentic Movement. They completed a pre and post Revised Adult Attachment Scale and reflected weekly on their experience through journaling. Participants reported that it was the structure of the Discipline of Authentic Movement that allowed them to feel more comfortable being themselves with others. The …

Exploring The Biological Basis For Exercise Neuroprotection In Parkinson’S Disease: A Cross-Sectional Study Of Exercise And Physical Activity On Inflammatory Cytokines And Neurotrophins, Leah Isabelle P. Alegre, Jacob M. Brewer, Adeline Florschutz, Kate E. Hamiltonthompson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Regular exercise and physical therapy are known to increase production of neurotrophins, including brain-derived neurotrophic factor (BDNF), and anti-inflammatory cytokines. These changes combine to theoretically protect and slow the progressive loss of neurons in Parkinson’s disease (PD). The purpose of this study was to examine the effect of exercise and physical activity on various anti-inflammatory and pro-inflammatory cytokines and neurotrophins in people with PD (PwP). This was a cross-sectional design involving PwP (n=37), aged 43-85 years, who participated in two 30-minute bouts of exercise (with brief rest breaks during and pre/post blood draws) separated by a week. Measures collected prior …

Assessment Of Energy And Hydration Demands Of Farm Workers In Mississippi, Mckenzie Lynne Hargrove

Theses and Dissertations

The agricultural community in Mississippi is critical to the state’s economy and the health of its communities. Farm workers meet these needs by performing highly demanding work with long hours of labor, limited resources, and stressful environmental conditions. The purpose of this investigation was to examine and measure indicators of physiological and behavioral adaptations to the heat such as whole body sweat rate (WBSR), sweat sodium (Na+) content, urine specific gravity (USG), and fluid intake, as well as determine total daily energy expenditure (TEE) and water influx (rH2O) via the doubly labeled water technique (DLW) in farm workers during the …

Application Of Occupational Therapy Task-Oriented For Chronic Post-Stroke Rehabilitation: A Case Study, Gia Nghi Vu

UNLV Theses, Dissertations, Professional Papers, and Capstones

Stroke remains the leading cause of long-term disability, with persistent upper extremity (UE) impairment limiting engagement in daily tasks, reducing quality of life and contributing to learned non-use in the chronic stage among stroke survivors. The Occupational Therapy Task Oriented (OTTO) approach is proposed to optimize occupational performance through the use of meaningful, functional and highly individualized tasks that enable clients to fulfill their valued roles and participate in desired daily activities. The purpose of this capstone project was to advance clinical skills by applying the OTTO approach to examine its effect on occupational performance and UE motor function in …

Harnessing Mechanobiology Of Resident Stem Cells To Refine Cell Based Therapeutics, Dakota R. Kamm

WUSM Theses and Dissertations – All Programs

Mesenchymal stem cells (MSCs) are resident cells residing with many adult tissues such as adipose tissue and bone marrow that have the potency for multiple lineage differentiation as well as the capacity to secrete a litany of beneficial factors to maintain homeostasis and promote tissue repair. Since 1995, MSCs have been used therapeutically to treat a variety of conditions from osteoarthritis to heart disease to muscle pathologies. Great leaps have been made in improving MSC-based therapies through optimization of culture methods and select enrichment of cellular subpopulations. More recently, the physical microenvironment of tissue in vivo and culture conditions in …

Examining Demographic And Contextual Differences In Stress-Related Sport Interference Among U.S. Collegiate Sport Participants, Heather Tran

UNLV Theses, Dissertations, Professional Papers, and Capstones

Collegiate athletes experience a range of stressors that may interfere with sport performance; however less is known about how stress-related sport interference varies across demographic groups and contexts. Guided by the transactional model of stress and coping, this study examined differences in stress-related sport interference by gender, race/ethnicity, and year in school, as well as across situational contexts (training, competition, and life outside of sport). Data were drawn from a secondary dataset of 288 collegiate sport participants who completed the Sport Interference Checklist (SIC). Independent samples t-test and analyses of variance (ANOVA) were used to examined demographic differences, and a …

Turf Toe And Sesamoid Fracture Case Study, Mason Cannon

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE This case presents the evaluation and management of a 15-year-old male multi-sport high school athlete. The athlete initially sustained a turf toe injury that progressed into a sesamoid fracture. This report showcases the clinical findings, treatment progression, and outcomes within a disablement model framework.

Prevalence Of Low Energy Availability (Lea) Risk In Division Iii Female Distance Athletes, Ciara Murphy

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE The objective of this study was to explore the prevalence of LEA among division III female distance athletes.

The Effectiveness Of An Educational Program On Young Swimmers Water Consumption And Dry Land Exercises, Maria Thibodeaux, Shelby Bay, Maddie Hoyt, Elizabeth Starns, Elizabeth Nix

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE/CONTEXT Although shown to improve performance, many young swimmers are reluctant to participate in dry land exercises.¹ They are also more likely to become dehydrated than their non-swimming counterparts, suggesting they are not adequately hydrating during activity and throughout their day.² Therefore, this study aimed to evaluate the impact of a four-week educational program on dry land exercises and water consumption.

From Focal Chondral Defect To Matrix-Induced Autologous Chondrocyte Implantation In An Active Adult: A Case Study, Zoey Scott

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

OBJECTIVE Present a clinical case detailing the undetermined consequential factors associated with FCD progression  in athletic populations, and the subsequent challenges.

Post-Surgical Dislocations: A Latarjet Procedure, Brianagh Dean, Kimberly S. Peer

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

BACKGROUND The glenohumeral joint is the most frequently dislocated joint in the body, with an incidence rate of 40.4 per 100,000 in men and 15.5 per 100,000 women. Recurrence rates following a first-time anterior shoulder dislocation range from 33-40%, particularly among adolescent collision-sport athletes. Arthroscopic Bankart repair is performed to address anterior instability, however recurrent instability may occur in the presence of glenoid bone loss. The Latarjet surgery is indicated in cases of recurrent anterior instability with significant bony deficiency, functioning through a triple-blocking mechanism increasing glenoid surface area via coracoid transfer, creating a dynamic sling effect from the conjoined …