Operations Research, Systems Engineering and Industrial Engineering Commons^™

Mechanical Properties Of Nanoparticles In The Drug Delivery Kinetics, Kaivon Assani, Amy Neidhard-Doll, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Nanoparticle formulation is a recently developed drug delivery technology with enhanced targeting potential. Nanoparticles encapsulate the drug of choice and delivers it to the target via a targeting molecules (ex. antigen) located on the nanoparticle surface. Nanoparticles can even be targeted to deeply penetrating tissue and can be modeled to deliver drugs through the blood brain barrier. These advancements are providing better disease targeting such as to cancer and Alzheimer’s. Various polymers can be manufactured into nanoparticles. The polymers examined in this paper are polycaprolactone (PCL), poly(lactic acid) (PLA), poly(lactic-co-glycolic acid) (PLGA), and poly(glycolic acid) (PGA). The purpose of this …

A Spatiotemporal Analysis Of Food Pantry Accessibility In Washington County, Arkansas, Coleman Warren

Industrial Engineering Undergraduate Honors Theses

Food pantries are an essential resource for impoverished and food insecure communities. Washington County, Arkansas has a food insecurity rate of 14.3% as compared to the national average of 10.9% (Feeding America, 2019). The Northwest Arkansas Food Bank has a robust pantry network in Washington County to support families and individuals who struggle with food insecurity.

We conducted a spatiotemporal analysis of food pantry accessibility in Washington County, Arkansas to evaluate the effectiveness of the food pantry network in Washington County at supporting communities with the most need. This analysis was conducted using the Two-Step Floating Catchment Area (2SFCA) method …

Assessing The Influence Of Health Policy And Population Mobility On Covid-19 Spread In Arkansas, Tayden Barretto

Industrial Engineering Undergraduate Honors Theses

The outbreak of COVID-19 has created a major crisis across the world since its start in 2019, and its influence on every realm of society is undeniable. Globally, more than 500 million cases have been recorded since March 2020, with almost 6 million deaths. In the wake of this crisis, many governments and health organizations have taken steps and precautions to mitigate its spread. These steps involve public mandates of information, reducing frequency of personal contact, and use of masks to minimize the risk of transmission. Current access to mobility data released from Google detailing population movements has provided a …

Analyzing Vulnerabilities In The Northwest Arkansas Highway Network Using Mathematical Optimization, Brandon Jerome

Industrial Engineering Undergraduate Honors Theses

The highway and bridge network is a critical infrastructure that allows for the free transportation of citizens and enables truck-borne freight transportation. Disruption of this system could be caused by a terrorist attack, natural disaster, growth of population, required repairs and upgrades, or collapse caused by old age or malfunction. In the event of a disruption cities and regions can experience increased traffic and supply chain shortages, thus causing cascading effects throughout surrounding areas. With this motivation, we develop a network interdiction optimization model to identify a limited subset of roads that, if disrupted, causes the greatest increase in the …

Investigations Of External Resources And The Impact Of Imaging On Patient Flow In The Emergency Department, Marisa Shehan

All Theses

The problems associated with Emergency Department (ED) crowding are numerous, varied, and complex. Though overcrowded Emergency Departments are frequently attributed to overcrowded hospitals, crowding is also impacted by bottlenecks in patient flow. While discrete-event simulation (DES) is commonly used to model ED flow, external resources are typically excluded from these models due to their complexity and the limited amount of known information for these processes. Instead, external resources such as consults, labs, and imaging are modeled using estimation and/or educated guesswork. In this study, the impact of imaging on patient flow was assessed through data analysis of specific imaging factors, …

Optimizing The Performance Of Analytical Chemistry Instrumentation, Srividya Sekar

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

Surrogate Optimization and Global Optimization approaches to optimize underlying functions have been studied and used extensively in the field of Operations Research. However, there are very few instances where these approaches have been applied and tested in applications with uncertainty. Additionally, extensive focus and effort have been put into developing highly complex metamodels rather than globally optimizing these metamodels. In this study, we propose a Mixed Integer Quadratically Constrained Program (MIQCP) based approach that globally optimizes a Quintic Multivariate Adaptive Regression Splines (QMARS) metamodel. The QMARS-MIQCP based optimization is applied to a global optimization framework called QMARS-MIQCP-OPT to optimize several …

Exploring Deep Learning In Finance, Abhijit Anand Anand Deshpande

Industrial, Manufacturing, and Systems Theses - Archive

Financial market analysis is process of analyzing market closely and predict the next move of market whether it will go up or down using historical data. Financial market is stochastic and has rapid changes over time, therefore it is very difficult to predict. The main goal of this work is to understand novel approaches of machine learning in finance, data parsing techniques, labelling the financial data. Furthermore, understand state of art Transformer model and implement and compare results with other traditional machine learning algorithms. Experiment carried out in python along with pytorch.

Interdiction Models To Disrupt The Operations Of Sex Trafficking And Other Forced Illicit Labor Networks, Michael T. Clark

All Theses

Sex traffickers often force their victims to work in both commercial sex markets and perform other illicit activities (e.g., drug dealing, theft, and fraud). Current literature has failed to address interdiction models that aim to disrupt all components of a sex traffickers’ operation, including these other illicit activities. In this thesis, we present a interdiction problem, and its single-level linear optimization reformulation, to reduce the profit of a human trafficking network concurrently operating in the commercial sex market and other illicit activity markets. Our novel formulation aims to investigate the practical implications of interdiction decisions made to disrupt a human …

Evaluating And Addressing The Transportation Challenges Of Small-Scale Farmers And Ranchers In Regional Food Systems, Narjes Sadeghiamirshahidi

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

During the last 20 years, there has been a significant increase in US consumers’ interest in local food. At the same time, there is substantial potential demand for crops produced by local small and mid-size farmers and ranchers whose market channels are short distance distributions Although there is a variety of definitions for local food, it often refers to direct-to-customer market channels for farmers and ranchers, including farmers’ markets and Community Supported Agriculture (CSA), as well as distribution through local businesses like restaurants, grocery stores, as well as local institutions such as hospitals and schools. However, small and mid-size farmers …

Leveraging Ai And Supply Chain Technologies With Thermal Imaging And Telemedicine For Early Detection And Prevention Of Covid-19 And Respiratory Infections In Urm Communities, Gohar Azeem

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

The underserved population could be at risk during the times of crisis, unless there is strong involvement from government agencies such as local and state Health departments and federal Center for Disease Control (CDC). The COVID-19 pandemic was a crisis of different proportion, creating a different type of burden on government agencies. Vulnerable communities including the elderly populations and communities of color have been especially hard hit by this pandemic. This forced these agencies to change their strategies and supply chains to support all populations receiving therapeutics. The National Science Foundation (NSF Award # 2028612) funded this research to help …

Implementing The Cms+ Sports Rankings Algorithm In A Javafx Environment, Luke Welch

Industrial Engineering Undergraduate Honors Theses

Every year, sports teams and athletes get cut from championship opportunities because of their rank. While this reality is easier to swallow if a team or athlete is distant from the cut, it is much harder when they are right on the edge. Many times, it leaves fans and athletes wondering, “Why wasn’t I ranked higher? What factors when into the ranking? Are the rankings based on opinion alone?” These are fair questions that deserve an answer. Many times, sports rankings are derived from opinion polls. Other times, they are derived from a combination of opinion polls and measured performance. …

Academic Advising Support Tool: An Optimization Approach, Spencer Loper

Industrial Engineering Undergraduate Honors Theses

More than ever, a college education is necessary to remain competitive in the job market. Therefore, colleges are dedicating numerous resources to ensure student success. Nonetheless, one of the most important factors of student success is proper academic advising. Students at the University of Arkansas and more specifically within the department of Industrial Engineering department are fortunate to have access to fantastic advising. However, given the volume of students, academic advisors do not have the time to talk through the nuance of every student’s long-term academic plan. The department does provide an eight-semester plan; however, students who have deviated from …

Selected Interdiction Games With Uncertain, Risk-Averse, And Simultaneous Play Considerations, Di H. Nguyen

All Dissertations

This dissertation examines two network interdiction problems: a shortest-path interdiction problem under uncertainty and a network interdiction problem in a simultaneous game. Both problems happen in two stages over a directed network, and involve a leader and a follower who have opposing interests.

In the first problem, the leader acts first to lengthen a subset of arcs, and a follower acts second to select a shortest path across the network. The cost for a follower’s arc consists of a base cost if the arc is not interdicted, plus an additional cost that is incurred if the arc is interdicted. The …

Design And Analysis Of Efficient Freight Transportation Networks In A Collaborative Logistics Environment, Vishal Badyal

All Dissertations

The increase in total freight volumes, reducing volume per freight unit, and delivery deadlines have increased the burden on freight transportation systems of today. With the evolution of freight demand trends, there also needs to be an evolution in the freight distribution processes. Today's freight transportation processes have a lot of inefficiencies that could be streamlined, thus preventing concerns like increased operational costs, road congestion, and environmental degradation. Collaborative logistics is one of the approaches where supply chain partners collaborate horizontally or/and vertically to create a centralized network that is more efficient and serves towards a common goal or objective. …

Comparing Actively Managed Mutual Fund Categories To Index Funds Using Linear Regression Forecasting And Portfolio Optimization, Luke Weiner

Industrial Engineering Undergraduate Honors Theses

The global investment industry offers a wide variety of investment products especially for individual investors. One such product, index funds, which are younger than actively managed mutual funds, have typically outperformed managed funds. Despite this phenomenon, investors have displayed a tendency to continue investing in actively managed funds. Although only a small percentage of actively managed funds outperform index funds, the costs of actively managed funds are significantly higher. Also, managed fund performances are most often determined by their fund category such as growth or real estate. I wanted to answer the following question for individual investors: can we …

Complexity Analysis And Parallel Implementation Of The Well Optimized Linear Finder (Wolf) Atmospheric Turbulence Compensation (Atc) Algorithm On Gpu Technology With Comparative Analysis Of Traditional Phase Diverse Atc Methods, Yang Xin

Theses and Dissertations

A new high-speed, high-accuracy general transfer function estimation method for diversitybased problems, known as the Well Optimized Linear Finder Algorithm (WOLF Algorithm), has been developed [1]. Compared to the traditional phase diversity ATC methods, the WOLF Algorithm has less computational complexity and better approximation of the Optical Transfer Function (OTF) and consequently the entrance pupil phases. We compare the time complexity between the traditional Phase Diversity atmospheric turbulence compensation approach and the WOLF Algorithm. The results show that the WOLF Algorithm is dramatically faster than traditional phase diversity methods theoretically. We also implement the time complexity results of the WOLF …

Forecasting Hypotension By Learning From Multivariate Mixed Responses.., Jodie Ritter

Electronic Theses and Dissertations

Blood Pressure is the main determinant of blood flow to organs. Hypotension is defined as a systolic blood pressure less than 90 mmHg or a diastolic blood pressure less than 50 mmHg. The severity and duration of hypotension is associated with low blood flow to organs often result in organ damage and a high mortality rate. Predicting hypotension prior to surgery and during the surgery can reduce the incidence and duration resulting in better patient outcomes. This thesis uses preoperative bloodwork and vital signs as well as perioperative vital signs in 5-minute increments as inputs to forecast hypotension. Hypotension can …

Developing A Model-Based Approach To Forecast A Competitor's System, Christopher A. Del Vecchio

Theses and Dissertations

The purpose of this research is to develop a model-based approach to intelligence forecasting of a competitor’s system. This analysis currently uses a document-based practice to capture all knowledge of the forecast and its development. A framework of antithesis processes, or Anti-Processes, were derived from the systems engineering technical processes. This was then combined with analytical tradecraft from the field of competitive technical intelligence to build a SysML reference model, which was then applied to a small case study to enhance and refine the model. The Anti-Process framework and SysML reference model provide a rigorous, model-based approach to intelligence forecasts …

Computational Speed Improvement Of The Well Optimized Linear Finder (Wolf) Transfer Function Estimation Methodology For Phase-Diverse Atmospheric Turbulence Compensation (Atc) Applications Using Pre-Calculated, Parallel Complex Exponential Phase Difference Chains, Erlin He

Theses and Dissertations

The Well-Optimized Linear Finder (WOLF) high-speed, phase-dominant, transfer function estimation method was developed by Professor William W. Arrasmith at Florida Institute of Technology. The novel, high-speed, transfer function estimation method is robust and can be applied to atmospheric turbulence compensation (ATC)/blind deconvolution optical imaging problems. The WOLF methodology uses a diversitybased approach with an adapted error metric to quickly remove effects of atmospheric turbulence and system noise effects present in an incoherent, optical imaging system. In this research, we improve performance of the WOLF algorithm by investigating the impact of applying parallel processing technology to pre-calculate an expanding set of …

Affordable Autonomous Vehicles For Deployment After Disastrous Events, Shannon Abolmaali

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

In disastrous events such as hurricanes and tornadoes, it has been observed that people get stranded and helpless without a feasible way to escape during those emergency situations. This became very evident during hurricanes, such as Katrina and Ida affecting millions of people seeking immediate rescue efforts. With the use of artificial intelligence and machine learning, we envision an autonomous vehicle, AV, which is able to find the most optimal and safest way to help those who are stranded to get them to a safe location. Electric vehicles, EV, and Autonomous Vehicles, AV, is becoming the future; minimizing the carbon …

Factors Affecting Hotel Recommendation: Before The Covid-19 Pandemic And After The Reopening, Boran Kim

UNLV Theses, Dissertations, Professional Papers, and Capstones

During the COVID-19 pandemic, numerous people lost their lives, and a lot of industries were affected. The hospitality industry was especially affected due to social distancing, travel restrictions, and safety issues. During that time, not only did customers' expectations change but their recommendation of hotels to friends and colleagues also changed. The current study used five factors (i.e., cleanliness, location, room, service, and value) to discover which factors were affecting hotel recommendation before the COVID-19 pandemic and after the reopening. This study used secondary data (online surveys) from one of the well-known integrated resorts located in the western United States. …

Fathom In Color: Expansion Of Reproduceable Color In Interference Pattern-Based Printed Motion And Depth Effects, Dovie Jeffcoat

All Theses

Value-added printed embellishments are increasingly sought after as brands compete for consumer attention. Fathom Optics’ method for printing motion and depth effects provides a cost-efficient, reduced waste embellishment option. One of Fathom’s current limitations is producing effects with vibrant color. The current standard practice for producing color Fathom Effects tends to darken and desaturate the final embellishment’s color. This study endeavors to determine how an ink color's components (hue, value and chroma) may determine a Fathom Effect’s contrast or intensity. To achieve this, fifteen color inks were selected to flexographically print the effect patterns. Samples were taken from each color …

A Study Of Scheduling Problems With Sequence Dependent Restrictions And Preferences, Nitin Srinath

All Dissertations

In some applications like fabric dying, semiconductor wafer processing, and flexible manufacturing, the machines being used to process jobs must be set up and serviced frequently. These setup processes and associated setup times between jobs often depend on the jobs and the sequence in which jobs are placed onto machines. That is, the scheduling of jobs on machines must account for the sequence-dependent setup times as well. These setup times can be a major factor in operational costs. In fabric dyeing processes, the sequence in which jobs are processed is also important for quality, i.e., there is a strong preference …

Double Tolerance Design In Stochastic Production Environments, Di Liu

All Dissertations

In a production process, it is impossible to produce parts with exact specifications. Thus, specific ranges, i.e., tolerances, are commonly employed to define intervals for the quality characteristics of conforming products (Wu & Tang (1998)). Usually, a product is deemed conforming when the measurement of the quality characteristic falls within the tolerance. If the measurement falls outside the tolerance, the product is nonconforming and it can be reworked or scrapped. One of the important engineering problems commonly faced by practitioners is to determine optimal engineering tolerances to be used in production. As a result, tolerance design techniques are widely used …

Examining The Impact Of Design Features Of Electronic Health Records Patient Portals On The Usability And Information Communication For Shared Decision Making, Rong Yin

All Dissertations

The use of the Electronic Health Records (EHR) patient portal has been shown to be effective in generating positive outcomes in patients’ healthcare, improving patient engagement and patient-provider communication. Government legislation also required proof of its meaningful use among patients by healthcare providers. Typical patient portals also include features such as health information and patient education materials. However, little research has examined the specific use of patient portals related to individuals with specific diseases such as inflammatory bowel diseases (IBDs). IBDs are life-long, not curable, chronic diseases that can impact the whole population. Individuals with IBDs may have higher needs …

The Impact Of Reliability In Conceptual Design - An Integrated Trade-Off Analysis, Tevari James Barker

Graduate Theses and Dissertations

Research presented in this paper focuses on developing models to estimate the systemreliability of Unmanned Ground Vehicles using knowledge and data from similar systems. Traditional reliability approaches often require detailed knowledge of a system and are used in later design stages as well as development, operational test and evaluation, and operations. The critical role of reliability and its impact on acquisition program performance, cost, and schedule motivate the need for improved system reliability models in the early design stages. Reliability is often a stand-alone requirement and not fully included in performance and life cycle cost models. This research seeks to …

Predicting The Likelihood And Scale Of Wildfires In California Using Meteorological And Vegetation Data, Matthew Walters

Graduate Theses and Dissertations

Wildfires have devastating ecological, environmental, economical, and public health impacts through the deterioration of water and air quality, CO2 emissions, property damage, and lung illnesses. The early detection and prevention of wildfires allow for the minimization of these risks. The use of Artificial Intelligence (AI) in wildfire detection and prediction has been highly researched as a tool to assist firefighters in stopping wildfires in its early stages. The three common wildfire prediction categories include image and video detection, behavior prediction, and susceptibility prediction. Data such as climate, weather, vegetation, satellite images, and historical wildfire data is most commonly used. Many …

Supervised Representation Learning For Improving Prediction Performance In Medical Decision Support Applications, Phawis Thammasorn

Graduate Theses and Dissertations

Machine learning approaches for prediction play an integral role in modern-day decision supports system. An integral part of the process is extracting interest variables or features to describe the input data. Then, the variables are utilized for training machine-learning algorithms to map from the variables to the target output. After the training, the model is validated with either validation or testing data before making predictions with a new dataset. Despite the straightforward workflow, the process relies heavily on good feature representation of data. Engineering suitable representation eases the subsequent actions and copes with many practical issues that potentially prevent the …

Model-Based Operational Performance Evaluation Of Augmented Reality Applications In Supported Employment Training, Ruo Lun Pan

Theses and Dissertations

Supported employment is a service provided by social enterprises to help persons with disabilities (PWD) to assimilate into their work environment and maintain their jobs for as long as possible. Social enterprises that provide such services are able to receive incentives from the government but they still rely on a limited funding. Augmented reality (AR) has been tested in various fields such as remote support and training employees, including PWDs. This thesis aims to evaluate the operational performance of augmented reality in supported employment using a model-based systems engineering approach paired with a simulation model. The simulation model evaluates three …

Hierarchical Value Decomposition For Effective On-Demand Ride Pooling, Hao Jiang, Pradeep Varakantham

Research Collection School Of Computing and Information Systems

On-demand ride-pooling (e.g., UberPool, GrabShare) services focus on serving multiple different customer requests using each vehicle, i.e., an empty or partially filled vehicle can be assigned requests from different passengers with different origins and destinations. On the other hand, in Taxi on Demand (ToD) services (e.g., UberX), one vehicle is assigned to only one request at a time. On-demand ride pooling is not only beneficial to customers (lower cost), drivers (higher revenue per trip) and aggregation companies (higher revenue), but is also of crucial importance to the environment as it reduces the number of vehicles required on the roads. Since …