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Articles 31 - 33 of 33
Full-Text Articles in Nanoscience and Nanotechnology
Pamam Dendrimer-Based Therapeutic And Diagnostic Nanodevices, Admira Bosnjakovic
Pamam Dendrimer-Based Therapeutic And Diagnostic Nanodevices, Admira Bosnjakovic
Wayne State University Dissertations
Dendrimers are ideal materials to be used in the emerging field of nanomedicine. Their nanoscale size and high density of functional groups on their peripheries allow them to be used for various biomedical applications. This work exploits dendrimers as drug delivery vehicles and a versatile platform for capturing biomarkers with improved sensitivity and specificity. Hydroxyl terminated poly(amidoamine) dendrimer (PAMAM-OH) was modified with a linker having amine group at the end and conjugated to two drugs, erythromycin (EM) and allopregnanonolne, respectively and evaluated in vitro. Both drugs were provided with a linker having carboxylic group required for conjugation reaction with dendrimer. …
Synthetic Levers Enabling Control Of Phase, Size And Morphology In Transition Metal Phosphide Nanoparticles (Fe, Ni), Elayaraja Muthuswamy
Synthetic Levers Enabling Control Of Phase, Size And Morphology In Transition Metal Phosphide Nanoparticles (Fe, Ni), Elayaraja Muthuswamy
Wayne State University Dissertations
ABSTRACT
SYNTHETIC LEVERS ENABLING CONTROL OF PHASE, SIZE AND MORPHOLOGY IN TRANSITION METAL PHOSPHIDE NANOPARTICLES (FE, NI)
by
ELAYARAJA MUTHUSWAMY
May 2011
Advisor:Dr. Stephanie L. Brock
Major: Chemistry
Degree: Doctor of Philosophy
This dissertation study focuses on (1) development of a synthetic strategy to control phase in nanoscale iron phosphides; (2) extension of the developed phase control strategy to the nanoscale nickel phosphide system with simultaneous control on size and morphology and (3) illustration of the enhanced reactivity of nanoscale oxide systems.
A synthetic strategy to control phase in nanoscale iron phosphides was developed to prepare phase-pure samples of …
Supercritical Carbon Dioxide Processing Of Nano - Clays And Polymer/Clay Nanocomposites, Mihai Manitiu
Supercritical Carbon Dioxide Processing Of Nano - Clays And Polymer/Clay Nanocomposites, Mihai Manitiu
Wayne State University Dissertations
Effective dispersion of the fillers in a polymer matrix and improvement of polymer-clay interactions are two key challenges in the field of nanocomposites. A novel processing method that utilizes the unique properties of supercritical carbon dioxide (scCO2) to disperse nano-clay and prepare a series of polymer/clay nanocomposites with enhanced properties was explored.
Significant dispersion was achieved using the scCO2 process with Cloisite 10A without the presence of an organic phase as evident by the absence of the diffraction peak in WAXD and the presence of individual tactoids that lost their parallel registry. The expanded flexible structure of the scCO2 processed …