Computer-Aided Engineering and Design Commons^™

A Maximum Energy Release Rate Computational Framework For Fatigue Crack Trajectory And Life Prediction Under Mixed-Mode Proportional And Nonproportional Loading, Nahla Helmy Matar

Theses and Dissertations

The problem of mixed-mode fatigue crack growth has been a persistent research challenge. The determination of fatigue crack propagation direction directly impacts the safety and integrity of components and structures, making it crucial in various industrial applications, including welded drilling pipes, aerospace, and automotive engineering. Unlike uniaxial loading, mixed-mode cracks tend to change direction frequently (kinking), and nonproportional loading adds to the complexity of the problem. This research aims to estimate the crack propagation direction and fatigue crack life in linear elastic materials subjected to mixed-mode (I+II) loading conditions under proportional or non-proportional cyclic loading. Numerical software was developed based …

A Virtual-Reality-Based Dental Simulator For Endodontics With Automated Formative Feedback, Yousef Salah Abo El Ela

Theses and Dissertations

Advancements in virtual reality (VR) and haptic technology are transforming the landscape of medical and dental education, offering new avenues for safe, immersive, and repeatable training experiences. Within dentistry, endodontics presents unique challenges for preclinical education due to anatomical complexity, limited access to extracted teeth, ethical concerns, and the shortcomings of conventional plastic models. Despite endodontics specific plastic teeth being available, they fall short of replicating the hardness of real extracted teeth, are relatively costly compared to generic plastic teeth, and are ultimately a disposable item which makes them inadequate as a sustainable long-term solution. Extracted teeth do a much …

Shape Memory Behavior In Medium To High Entropy Shape Memory Alloys: Design, Prediction, And Experimental Analysis, Hatim Raji

Theses and Dissertations

This dissertation provides a data-driven system integrating synthetic data generation and machine learning (ML) techniques to create multicomponent SMA compositions with specific transformation temperatures (TTs). Models were trained to represent the nonlinear dependencies influencing martensitic transformation behavior by using elemental, thermodynamic, and process-related aspects. The capacity of the ML models on medium entropy NiTiHfPd and high entropy NiTiHfZrCu systems accuracy was confirmed by experimental validation showing TTs closely matched with model outputs.

Co-Designing Manufacturing Systems For Robustness And Resilience: A Decision-Based Design Perspective, Mathew Baby

Theses and Dissertations

Manufacturing systems (MSs) comprise various stakeholders associated with the manufacture and supply of products required by customers and are interrelated by the flow of materials and information. The interrelated stakeholders make system-specific decisions and stakeholder-specific decisions across multiple levels of a decision hierarchy to satisfy many conflicting system-specific and stakeholder-specific requirements that define system and stakeholder performances. Given the stakeholder interrelations and conflicting nature of system-specific and stakeholder-specific requirements, system and stakeholder performances are correlated and conflicting.

In the Industry 5.0 era, there is an increased emphasis on the creation and equitable distribution of value among all the stakeholders in …

Experimental And Theoretical Fracture Analysis Of Additively Manufactured Orthotropic V-Notches, Venkata Siva Sainath Bavapuram

Theses and Dissertations

This study presents a comprehensive investigation into the fracture behavior of additively manufactured orthotropic V-notched components made of Acrylonitrile Butadiene Styrene (ABS) material. The research integrates both theoretical and finite element approaches to evaluate stress intensity factors (SIFs) in Modes-I and II, which are fundamental in characterizing stress field distributions around notches under applied loading conditions. Unlike isotropic materials, where stress fields depend only on geometry of the component, the anisotropic nature of 3D-printed ABS introduces a dependency on material properties that necessitate different approaches to include anisotropy of the material.

Tensile specimens are 3D-printed with specific material orientations to …

Experimental And Numerical Analysis Of Laminar And Transitional Flow Through Annular Corrugated Pipes, Joseph Russell Sargent

Theses and Dissertations

This dissertation presents studies on pressure loss through annular corrugated pipes to determine a friction factor coefficient using nitrogen. Ten different corrugated pipes’ geometries were evaluated via testing and experimentation. The ratio of corrugation height to inner diameter varied from 0.233 to 0.333 and the ratio of corrugation pitch to inner diameter varied from 0.181 to 0.446. Nitrogen flow rates between 0.25 to 94.4 standard liters per minute were used, resulting in Reynolds numbers, based on the corrugated pipe inner diameter, from 100 to 23,000. The experimental set-up was validated using smooth-pipe pressure loss measurements and the derived friction factor …

An Application Of Cfd To Support The Development Of Treatment Strategies And Technology For The Management Of Cystic Fibrosis In Pediatric Patients, Morgan L. Thomas

Theses and Dissertations

Inhaled medications are a key treatment modality in multiple lung-related diseases and disorders. Considering children with cystic fibrosis (CF), improvements in the delivery of aerosol antibiotics have the potential to better eradicate bacterial lung infections, preserve lung function and thereby further extend lifespans and quality of life. The overall objective of this dissertation was to expand and validate CFD models for predicting the deposition of pharmaceutical aerosols throughout the airways and apply these models to understand the targeted delivery of inhaled antibiotics to children with CF. To accomplish this goal, three contributions were made. First, CFD methodologies for modeling aerosol …

Mechanical Characterization Of Functionally Graded M300 Maraging Steel Cellular Structures, Bradley Jay Sampson

Theses and Dissertations

Traditional methods for increasing the energy absorption of a structure involve using a stronger material or increasing the volume of the structure, resulting in a higher cost or additional weight. Additive manufacturing (AM) can be used to maximize the energy absorption of materials with the ability to create complex geometries such as cellular structures. Previous work has shown that the energy absorption of additively manufactured parts can be improved through functionally graded cellular structures; however, this strategy has not been applied to ultra-high strength steel materials. This work characterizes the effect of multiple functional-grading strategies (e.g. uniform, rod-graded, size-graded) on …

Deep Learning And Generative Ai Approaches For Automated Diagnosis And Personalized Treatment: Bridging Machine Learning, Medicine, And Biomechanics In Predicting Tissue Mechanics And Biomaterial Properties., Yasin Shokrollahi

Theses and Dissertations

Machine learning, particularly deep neural networks, has demonstrated significant potential in predicting high-dimensional tasks across various domains. This work encompasses a detailed review of Generative AI in healthcare and three studies integrating machine learning with finite element analysis for predicting biomechanical behaviors and properties. Initially, we provide a comprehensive overview of Generative AI applications in healthcare, focusing on Transformers and Denoising Diffusion models and suggesting potential research avenues to address existing challenges.

Subsequently, we addressed soccer-related ocular injuries by combining finite element analysis and machine learning to predict retinal mechanics following a soccer ball hit rapidly. The prediction errors are …

Molecular Dynamics Of High Temperature Hydrogen Attack, Mike Travis Bodden Connor

Theses and Dissertations

High temperature hydrogen attack (HTHA) is a damage mechanism that only affects carbon steel and low alloy material. Most of the data regarding HTHA are experimental-driven. Even though this approach has been successful, there are still much more things that the oil and gas industry does not understand about HTHA. The regions that were considered safe (below the Nelson curves) have experienced catastrophic failure. Our research consists of performing Molecular Dynamics (MD) and the Nudge Elastic Band (NEB) calculation of HTHA to better understand the atomistic behavior of this damage mechanism.

A Constitutive Material Model For Simulating Texture Evolution And Anisotropy Effects In Cold Spray., Creston Michael Giles

Theses and Dissertations

Cold spray has seen rapid advancement since its inception and has shown significant potential as a method of additive manufacturing. However, the large plastic deformation and repeated heating/cooling cycles that the material undergoes during the cold spray process can result in gradients in material structure and large residual stresses. The purpose of this study is to extend the existing EMMI material model to include anisotropic material response through the use of orientation distribution functions to predict residual stresses and anisotropy resulting from cold spray and similar additive manufacturing processes. Through the use of a finite element simulation, yield surfaces for …

Surrogate Model-Based Design Optimization Of A Mobile Deployable Structure For Overpressure Load And Vehicular Impact Mitigation, Daniela F. Tellkamp

Theses and Dissertations

Artificial Neural Network (ANN) ensemble and Response Surface Method (RSM) surrogate models were generated from Finite Element (FE) simulations to predict the overpressure load and vehicle impact response of a novel rapidly deployable protective structure. A Non-dominated Sorting Genetic Algorithm-II (NSGA-II) was used in conjunction with the surrogate models to determine structure topology input variable configurations which were suited to produce the optimal balance of minimum mass, minimum rotation angle, minimum displacement, and maximum total length of the deployable structure. The structure was designed to retract into a container, be lightweight to facilitate transportation, and be able to adapt to …

Lattice Boltzmann-Based Sharp-Interface Schemes For Conjugate Heat And Mass Transfer And Diffuse-Interface Schemes For Dendritic Growth Modeling, Nanqiao Wang

Theses and Dissertations

Analyses of heat and mass transfer between different materials and phases are essential in numerous fundamental scientific problems and practical engineering applications, such as thermal and chemical transport in porous media, design of heat exchangers, dendritic growth during solidification, and thermal/mechanical analysis of additive manufacturing processes. In the numerical simulation, interface treatment can be further divided into sharp interface schemes and diffuse interface schemes according to the morphological features of the interface. This work focuses on the following subjects through computational studies: (1) critical evaluation of the various sharp interface schemes in the literature for conjugate heat and mass transfer …

Modeling Of Patient-Specific Periaortic Mechanics And Pulmonary Artery Hemodynamics Based On Phase-Contrast Magnetic Resonance Imaging Sequences., Johane H. Bracamonte

Theses and Dissertations

Inverse modeling in cardiovascular medicine is a collection of methodologies that can provide non-invasive patient-specific estimations of clinical risk factors using medical imaging as inputs. Its incorporation into clinical practice has the potential to improve diagnosis and treatment planning with low associated risks and costs.

Herein, three different phase contrast magnetic resonance imaging (MRI) modalities were implemented as input data, displacement encoding with stimulated echoes (DENSE MRI) applied, and time-resolved velocity encoding phase-contrast MRI, in 1D and 3D, applied to pulmonary artery (PA) hemodynamics.

A model to account for the effect of periaortic interactions due to static and dynamic structures …

Development And Optimization Of A Low Volume Air-Jet Dry Powder Inhaler (Dpi) Platform For The Delivery Of High Dose Aerosolized Powder To Infants, Connor Howe

Theses and Dissertations

The goal of this research project was to develop an infant air-jet dry powder inhaler (DPI) platform for high-efficiency nose-to-lung (N2L) aerosol administration to infants through optimization of individual system components followed by expansion of the system to higher doses and different formulations using a new approach. Primary challenges associated with aerosol delivery to infants using the N2L route include the extremely narrow extrathoracic airways, short inspiratory times (~0.2 sec), low safe airway pressure (H₂O), and very low volumes of air (~10 mL) available to form the aerosol. The infant air-jet DPI system was comprised of three main …

The Development Of A Finite Element Model For Ballistic Impact Predictions, Richard Allen Perkins

Theses and Dissertations

Concrete is a widely used product and is an important application throughout industry due to its inexpensive cost and wide range of applications. This work focuses on understanding the behavior of high strength concrete in high strain rate ballistic impact loading scenarios. A finite element analysis was created with the implementation of the Concrete Damage and Plasticity Model 2 (CDPM2) to represent the material behavior. The model’s parameters were calibrated to existing literature and the results were analyzed by a comparison of the impact velocity to residual velocity and a qualitative assessment of the impact crater. The model captured the …

Additive Manufacturing Of Cork, A Cold Spray Technology, Kimberly Kay Dickey

Theses and Dissertations

Cold Spray Additive Manufacturing is a technology capable of mass manufacturing components with complicated geometry and coating substrates in hard-to-reach areas. In addition, cold spray also has the ability of conducting a green manufacturing process, with zero waste of renewable feed material, and zero gas and chemical emission. This paper investigates solely cold spray as an additive manufacturing technology with cork as the natural material. CFD results were used to predict the physical behavior of air and the cork particles. After unsuccessful coatings, final results showed that when moisture is added, cork is successfully cold sprayed, and agglomeration is experienced. …

A Self-Tunable Piezoelectric Energy Harvester, Ashraf Hussein

Theses and Dissertations

In this study, a new technique to harvest energy using inertial vibration energy harvesters is introduced. A triple-layer piezoelectric beam with a self-tunable frequency was developed in order to respond to variable-frequency excitations, thereby maintaining the beam in a state of resonance for maximum power output. The tuning mechanism managed to change the natural frequency of the beam in the range of 2.27 ���� to 6.25 ����. In this case, the output voltage could be raised from 12�� to 23��.

A mathematical model was developed to investigate the natural frequency, the output voltage, and the output power of the beam …

Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence

Theses and Dissertations

Combining vibrating mesh nebulizers with additional new technologies leads to substantial improvements in pharmaceutical aerosol delivery to the lungs across therapeutic administration methods. In this dissertation, streamlined components, aerosol administration synchronization, and/or Excipient Enhanced Growth (EEG) technologies were utilized to develop and test several novel devices and aerosol delivery systems. The first focus of this work was to improve the poor delivery efficiency, e.g., 3.6% of nominal dose (Dugernier et al. 2017), of aerosolized medication administration to adult human subjects concurrent with high flow nasal cannula (HFNC) therapy, a form of continuous-flow non-invasive ventilation (NIV). The developed Low-Volume Mixer-Heater (LVMH) …

Peridynamic Approaches For Damage Prediction In Carbon Fiber And Carbon Nanotube Yarn Reinforced Polymer Composites, Forrest E. Baber

Theses and Dissertations

Aerospace structures are increasingly utilizing advanced composites because of their high specific modulus and specific strength. While the introduction of these material systems can dramatically decrease weight, they pose unique certification challenges, often requiring extensive experimental testing in each stage of the design cycle. The expensive and time-consuming nature of experimental testing necessitates the advancement of simulation methodologies to both aid in the certification process and assist in the exploration of the microstructure design space.

Peridynamic (PD) theory, originating from Sandia National Lab’s in the early 2000’s, is a nonlocal continuum-based method that reformulates the equation of motion into an …

Strategies And Devices For Improving Respiratory Drug Delivery To Infants And Children With Cystic Fibrosis, Karl Bass

Theses and Dissertations

Cystic Fibrosis (CF) is a degenerative disease, which causes thickening of the airway surface liquid and reduced mucociliary clearance, which provides an ideal habitat for bacterial infections. Early treatment of CF in children can prevent chronic infection, improve quality of life, and increase life expectancy. The most predominant bacteria found in CF-diseased lungs is Pseudomonas aeruginosa (Pa), which can be treated with inhaled tobramycin. Excipient enhanced growth (EEG) powder formulations are well suited for administering tobramycin to children, as the EEG approach provides minimal upper airway loss and targeted drug delivery. This method uses an initially small aerosol for high …

Optimizing Nasal Cannulas For Infants Using Computational Fluid Dynamics, Ahmad El-Achwah Mr.

Theses and Dissertations

Aerosolized medications can potentially be delivered to the lungs of infants through a nasal cannula interface. However, nose-to-lung delivery technologies currently allow for ~1% of the loaded dose to reach an infant’s lungs. Conventional dry powder inhalers (DPI) are superior to other types of inhalers in many ways. However, passive DPIs that operate based on user inhalation and require large volumes of airflow are not applicable to infants. To overcome this challenge, positive pressure DPIs have been developed that enable aerosol delivery to infants. Unless an adequate nasal interface is used with these devices, a significant amount of drug will …

A Practical Tool For The Determination Of Surface Stresses In Railroad Bearings With Different Contact Geometries And Load Conditions Using Finite Element Analysis, Michael A. Mason

Theses and Dissertations

The connection between contact geometry and fatigue in tapered roller bearings utilized in the railroad environment is still of interest. Roller bearings for railroad applications are typically precision ground with crowned contact geometries to prevent edge loading of components. This normally results in completely elastic Hertzian contact stresses under standard railcar loads. However, under extreme load conditions, detrimental edge loading has been known to occur. It is proposed to develop a tool, using finite element analysis, that can be utilized to optimize complex raceway crown geometries for severe applications.

A successful implementation of this tool is presented and validated using …