Open Access. Powered by Scholars. Published by Universities.®

Other Engineering Science and Materials Commons™

Open Access. Powered by Scholars. Published by Universities.®

Mechanical Engineering

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 151 - 180 of 692

Full-Text Articles in Other Engineering Science and Materials

Control Of Change Of Phase Through Physical Surface Shaping, Troy Anderson, Sidy Ndao, Craig Zuhlke, Dennis Alexander, George Gogos Jun 2021

Control Of Change Of Phase Through Physical Surface Shaping, Troy Anderson, Sidy Ndao, Craig Zuhlke, Dennis Alexander, George Gogos

Department of Mechanical and Materials Engineering: Faculty Publications

A system embodiment includes , but is not limited to , a solid structure configure to contact each of a material in a liquid phase and a material in a vapor phase , the solid structure including a plurality of microstructures protruding at angles relative to a horizontal plane ; and a layer of nanoparticles positioned on the plurality of microstructures , the layer of nanoparticles having a composition that is at least one of a same material as the plurality of microstructures and an oxide of the same material as the plurality of microstructures , the plurality of microstructures …

Go to article

Minimally Invasive Delivery Of 3d Shape Recoverable Constructs With Ordered Structures For Tissue Repair, Shixuan Chen, Mark Alan Carlson, Xiaowei Li, Aleem Siddique, Wuqiang Zhu, Jingwei Xie Jun 2021

Minimally Invasive Delivery Of 3d Shape Recoverable Constructs With Ordered Structures For Tissue Repair, Shixuan Chen, Mark Alan Carlson, Xiaowei Li, Aleem Siddique, Wuqiang Zhu, Jingwei Xie

Department of Mechanical and Materials Engineering: Faculty Publications

Minimally invasive procedures are becoming increasingly more common in surgery. However, the biomaterials capable of delivering biomimetic, three-dimensional (3D) functional tissues in a minimally invasive manner and exhibiting ordered structures after delivery are lacking. Herein, we reported the fabrication of gelatin methacryloyl (GelMA)-coated, 3D expanded nanofiber scaffolds and their potential applications in minimally invasive delivery of 3D functional tissue constructs with ordered structures and clinically appropriate sizes (4 cm × 2 cm × 1.5 mm). GelMA-coated, expanded 3D nanofiber scaffolds produced by combining electrospinning, gas-foaming expansion, hydrogel coating, and crosslinking are extremely shape recoverable after release of compressive strain, displaying …

Go to article

Development Of A Marine Biodegradable Target Balloon, Blake Samuel Robinson, Arash Sam Akhavi, David Leonardo Albarran-Martinez Jun 2021

Development Of A Marine Biodegradable Target Balloon, Blake Samuel Robinson, Arash Sam Akhavi, David Leonardo Albarran-Martinez

Materials Engineering

The US Navy utilizes PVC target balloons, known as Killer Tomatoes, that are inflated onboard a naval vessel then deployed into the ocean to calibrate a variety of weaponry. The Navy has requested the investigation of biodegradable polymers to replace the PVC in attempts to reduce ocean waste that is generated from the leftover PVC material. After communicating with American Pacific Plastic Fabricators (APPF), the current manufacturer of the Killer Tomatoes, we gained an understanding of the manufacturing process and the material requirements that would allow a new material to be integrated into their current process. Two proprietary, trial polymers …

Go to article

Maize Tassel Detection From Uav Imagery Using Deep Learning, Aziza Alzadjali, Mohammed H. Alali, Arun Narenthiran Weeranampalayam Sivakumar, Jitender S. Deogun, Stephen Scott, James C. Schnable, Yeyin Shi Jun 2021

Maize Tassel Detection From Uav Imagery Using Deep Learning, Aziza Alzadjali, Mohammed H. Alali, Arun Narenthiran Weeranampalayam Sivakumar, Jitender S. Deogun, Stephen Scott, James C. Schnable, Yeyin Shi

Department of Mechanical and Materials Engineering: Faculty Publications

The timing of flowering plays a critical role in determining the productivity of agricultural crops. If the crops flower too early, the crop would mature before the end of the growing season, losing the opportunity to capture and use large amounts of light energy. If the crops flower too late, the crop may be killed by the change of seasons before it is ready to harvest. Maize flowering is one of the most important periods where even small amounts of stress can significantly alter yield. In this work, we developed and compared two methods for automatic tassel detection based on …

Go to article

Investigation Of Topological Phonons In Discrete Mechanical Metamaterials, Kai Qian May 2021

Investigation Of Topological Phonons In Discrete Mechanical Metamaterials, Kai Qian

Dissertations

The study of topological mechanical metamaterials is a new emerging field that focuses on the topological properties of artificial mechanical structures. Inspired by topological insulators, topological mechanism has attracted intensive attention in condensed matter physics and successfully connected the quantum mechanical descriptions of electrons with the classical descriptions of phonons. It has led to experiments of mechanical metamaterials possessing topological characteristics, such as topologically protected conducting edges or surfaces without back-scattering. This dissertation presents a new experimental approach for mechanically engineering topological metamaterials based on patterning magnetically coupled spinners in order to localize the propagation of vibrations and evaluate different …

Go to article

Uavs For Vegetation Monitoring: Overview And Recent Scientific Contributions, Ana I. De Castro, Yeyin Shi, Joe Mari Maja, Jose M. Pena May 2021

Uavs For Vegetation Monitoring: Overview And Recent Scientific Contributions, Ana I. De Castro, Yeyin Shi, Joe Mari Maja, Jose M. Pena

Department of Mechanical and Materials Engineering: Faculty Publications

This paper reviewed a set of twenty-one original and innovative papers included in a special issue on UAVs for vegetation monitoring, which proposed new methods and techniques applied to diverse agricultural and forestry scenarios. Three general categories were considered: (1) sensors and vegetation indices used, (2) technological goals pursued, and (3) agroforestry applications. Some investigations focused on issues related to UAV flight operations, spatial resolution requirements, and computation and data analytics, while others studied the ability of UAVs for characterizing relevant vegetation features (mainly canopy cover and crop height) or for detecting different plant/crop stressors, such as nutrient content/deficiencies, water …

Go to article

Three-Dimensional Shape Analysis Of Peripapillary Retinal Pigment Epithelium-Basement Membrane Layer Based On Oct Radial Images, Junfei Tong, Pengfei Dong, Sachin Kedar, Deepta Ghate, Linxia Gu May 2021

Three-Dimensional Shape Analysis Of Peripapillary Retinal Pigment Epithelium-Basement Membrane Layer Based On Oct Radial Images, Junfei Tong, Pengfei Dong, Sachin Kedar, Deepta Ghate, Linxia Gu

Department of Mechanical and Materials Engineering: Faculty Publications

The peripapillary retinal pigment epithelium-basement membrane (ppRPE/BM) layer angle was recently proposed as a potential index for estimating intracranial pressure noninvasively. However, the ppRPE/BM layer angle, measured from the optical coherence tomography (OCT) scans, varied across the radial directions of the optic disc. This made the ppRPE/BM layer angle difficult to be utilized in its full potential. In this study, we developed a mathematical model to quantify the ppRPE/BM layer angles across radial scans in relation to the ppRPE/BM 3D morphology in terms of its 3D angle and scanning tilt angles. Results showed that the variations of the ppRPE/BM layer …

Go to article

On The Comparison Of Flow Physics Between Minimal And Extended Flow Units In Turbulent Channels, Ethan A. Davis, Siamak Mirfendereski, Jae Sung Park May 2021

On The Comparison Of Flow Physics Between Minimal And Extended Flow Units In Turbulent Channels, Ethan A. Davis, Siamak Mirfendereski, Jae Sung Park

Department of Mechanical and Materials Engineering: Faculty Publications

Direct numerical simulations were performed to study the effects of the domain size of a minimal flow unit (MFU) and its inherent periodic boundary conditions on flow physics of a turbulent channel flow in a range of 200 ≤ Reτ ≤ 1000. This was accomplished by comparing turbulent statistics with those computed in sub-domains (SD) of extended domain simulations. The dimensions of the MFU and SD were matched, and SD dynamics were set to minimize artificial periodicities. Streamwise and spanwise dimensions of healthy MFUs were found to increase linearly with Reynolds number. It was also found that both MFU …

Go to article

Mixed Mode Crack Propagation In Iliac Bone, E. Baesu, Dm. Iliescu, Bv. Radoiu, S. Halichidis Apr 2021

Mixed Mode Crack Propagation In Iliac Bone, E. Baesu, Dm. Iliescu, Bv. Radoiu, S. Halichidis

Department of Mechanical and Materials Engineering: Faculty Publications

Bone is a complex material that can be regarded as an anisotropic elastic composite material. The problem of crack propagation in hu- man bone is analyzed by using a generalization of the maximum tensile stress criterion (MTS). The results concern the critical stress for crack propagation and the direction of the crack path in Iliac bone.

Go to article

Special Issue “Cfd Modeling Of Complex Chemical Processes: Multiscale And Multiphysics Challenges”, Li Xi, De-Wei Yin, Jae Sung Park Apr 2021

Special Issue “Cfd Modeling Of Complex Chemical Processes: Multiscale And Multiphysics Challenges”, Li Xi, De-Wei Yin, Jae Sung Park

Department of Mechanical and Materials Engineering: Faculty Publications

No abstract provided.

Go to article

Improving Accuracy Of Unmanned Aerial System Thermal Infrared Remote Sensing For Use In Energy Balance Models In Agriculture Applications, Mitchell S. Maguire, C.M.U. Neale, Wayne E. Woldt Apr 2021

Improving Accuracy Of Unmanned Aerial System Thermal Infrared Remote Sensing For Use In Energy Balance Models In Agriculture Applications, Mitchell S. Maguire, C.M.U. Neale, Wayne E. Woldt

Department of Mechanical and Materials Engineering: Faculty Publications

Unmanned aerial system (UAS) remote sensing has rapidly expanded in recent years, leading to the development of several multispectral and thermal infrared sensors suitable for UAS integration. Remotely sensed thermal infrared imagery has been used to detect crop water stress and manage irrigation by leveraging the increased thermal signatures of water stressed plants. Thermal infrared cameras suitable for UAS remote sensing are often uncooled microbolometers. This type of thermal camera is subject to inaccuracies not typically present in cooled thermal cameras. In addition, atmospheric interference also may present inaccuracies in measuring surface temperature. In this study, a UAS with integrated …

Go to article

Six-Sigma Quality Management Of Additive Manufacturing, Hui Yang, Prahalad Rao, Timothy Simpson, Yan Lu, Paul Witherell, Abdalla R. Nassar, Edward Reutzel, Soundar Kumara Apr 2021

Six-Sigma Quality Management Of Additive Manufacturing, Hui Yang, Prahalad Rao, Timothy Simpson, Yan Lu, Paul Witherell, Abdalla R. Nassar, Edward Reutzel, Soundar Kumara

Department of Mechanical and Materials Engineering: Faculty Publications

Quality is a key determinant in deploying new processes, products, or services and influences the adoption of emerging manufacturing technologies. The advent of additive manufacturing (AM) as a manufacturing process has the potential to revolutionize a host of enterprise-related functions from production to the supply chain. The unprecedented level of design flexibility and expanded functionality offered by AM, coupled with greatly reduced lead times, can potentially pave the way for mass customization. However, widespread application of AM is currently hampered by technical challenges in process repeatability and quality management. The breakthrough effect of six sigma (6S) has been demonstrated in …

Go to article

Anisotropic Scaffolds For Peripheral Nerve And Spinal Cord Regeneration, Wen Xue, Wen Shi, Yunfan Kong, Mitchell Kuss, Bin Duan Apr 2021

Anisotropic Scaffolds For Peripheral Nerve And Spinal Cord Regeneration, Wen Xue, Wen Shi, Yunfan Kong, Mitchell Kuss, Bin Duan

Department of Mechanical and Materials Engineering: Faculty Publications

The treatment of long-gap (>10 mm) peripheral nerve injury (PNI) and spinal cord injury (SCI) remains a continuous challenge due to limited native tissue regeneration capabilities. The current clinical strategy of using autografts for PNI suffers from a source shortage, while the pharmacological treatment for SCI presents dissatisfactory results. Tissue engineering, as an alternative, is a promising approach for regenerating peripheral nerves and spinal cords. Through providing a beneficial environment, a scaffold is the primary element in tissue engineering. In particular, scaffolds with anisotropic structures resembling the native extracellular matrix (ECM) can effectively guide neural outgrowth and reconnection. In …

Go to article

Dynamics Of Running Processes In The Area Of Underless Water Intake, D.R. Bazarov, M.P. Tashkhanova, A. Gayur, M. Sapaeva Mar 2021

Dynamics Of Running Processes In The Area Of Underless Water Intake, D.R. Bazarov, M.P. Tashkhanova, A. Gayur, M. Sapaeva

Irrigation and Melioration

The paper analyzes the dynamics of channel processes based on the results of field studies of the Amudarya River at the site of the damless water intake to the Karshi Magistralny Canal (KMK) and developed recommendations for improving the water intake conditions. Based on the results of field studies of the head section of the inlet channel, an assessment of the state of the Amudarya river bed in the water intake zone was made. The results of studies of the hydraulic and alluvial regimes of the Amu Darya River in the area of the damless water intake are generalized The …

Go to article

Determination Of The Optimal Hydromodule Of Irrigation Network For Drip Irrigation, R.Zh. Karshiev, A. Urazkeldiev, A.H. Radjabov, A.I. Ernazarov Mar 2021

Determination Of The Optimal Hydromodule Of Irrigation Network For Drip Irrigation, R.Zh. Karshiev, A. Urazkeldiev, A.H. Radjabov, A.I. Ernazarov

Irrigation and Melioration

Most of the irrigation canals operating in the country were built in the 60s and 80s of the XX century, their hydraulic parameters were designed and adapted to the irrigation regimes of agricultural crops, mainly for surface irrigation, and the average hydromodule values were 0,8-1,0 l / s. , the hydraulic parameters of the channel are designed to carry large volumes of water in a short period of time. Over the next 3-4 years, the introduction of water-saving technologies in the irrigation of agricultural crops by farms and "Clusters" requires the improvement of hydraulic methods of irrigation management, the use …

Go to article

Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, Kh.Sh. Gafforov, Sh.D. Sh.D.Tursunboev Mar 2021

Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, Kh.Sh. Gafforov, Sh.D. Sh.D.Tursunboev

Irrigation and Melioration

The importance of assessing past and future climate differences plays an important role in future planning in relation to climate change. This situation requires urgent and concerted action in several areas: technology, infrastructure, politics, economics, and the environment. The article evaluates the impact of changes in precipitation intensity on the water level in the global circulation model (GCM) RCP 4.5 and 8.5 scenarios in the 2030s, 2050s, and 2070s. This study is a useful reference for improving water resource management and ensuring the sustainability of agricultural products in the future, as well as for improving operational water management and agricultural …

Go to article

Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, В.K. Saliev Mar 2021

Assessment Of The Impact Of Climate Change On Hydrological Processes In The Chirchik River Basin, В.K. Saliev

Irrigation and Melioration

The article examines the assessment of the state and problems of irrigation water use in the republic in the past and in the near future. A comparative analysis of the state of water resources use for the period of the last 30 years from 1989 to 2019 was carried out.According to the estimates, own water withdrawal for 5 years (2014/15-2018/19) shows that an average of 53.2 m3, including 50.5 billion m3 from rivers At present (2018-2019), an average of 57.06 billion m3 of water is taken for irrigation of 4.289 million hectares of land, against 63.02 billion m3 approved in …

Go to article

Environmental Damage Caused By Transport Equipment Waste, M. Radkevich, K. Shipilova, M. Abdukodirova, O. Pochugevski Mar 2021

Environmental Damage Caused By Transport Equipment Waste, M. Radkevich, K. Shipilova, M. Abdukodirova, O. Pochugevski

Irrigation and Melioration

The article suggests a new approach to the monetary assessment of the damage caused to the environment by the processed waste of the transport sector. The proposed assessment method is based on the waste collection factor, all types of irretrievable losses and the volume of necessary compensatory release of materials. Based on a survey among vehicle owners, it was found that the solid waste collection rate is about 50 %, while the waste collection rate for operating fluids does not exceed 32 %. In this regard, the bulk of the damage to the environment is caused by liquid waste. Calculations …

Go to article

Research Of Stress-Deformed State Of Multi-Connected Complex Shell Structures, Т.М. Маvlanov, Sh.O. Khudainazarov, B. Yalgashev, O.S. Nurova Mar 2021

Research Of Stress-Deformed State Of Multi-Connected Complex Shell Structures, Т.М. Маvlanov, Sh.O. Khudainazarov, B. Yalgashev, O.S. Nurova

Irrigation and Melioration

Conducting numerical experiments for complex structurally inhomogeneous structures allows us to understand the qualitative picture of the effect of various parameters in a wide range of studies and to give sound recommendations at the design stage for conducting laboratory model and field experiments. In this paper, on the basis of the classical theory of elasticity, the basic equations characterizing the stress-strain state of complex multiply connected shell structures are given and a specific problem is solved. At the same time, some of the structural elements have viscoelastic properties. When solving the problem, the behavior of the structure for the n-th …

Go to article

To The Determination Of The Critical Circuit Speed Of The Sharing Drum, Kh. Kh. Igamberdiev, A.B. Mukhitdinov Mar 2021

To The Determination Of The Critical Circuit Speed Of The Sharing Drum, Kh. Kh. Igamberdiev, A.B. Mukhitdinov

Irrigation and Melioration

The article is devoted to the theoretical definition of the critical circumferential speed of the stripping drum of a kena harvester, which depends on the drum diameter, diameter and weight of the stems. It was determined from the equality of the change in the momentum of the stem during impact, i.e. from a shock impulse acting on the stem. The shock impulse is determined when the drum blade touches the stem in the process of stripping, which acts on the mass of the entire stem. The duration of the impact of the drum stripping on the stem was determined from …

Go to article

An Innovative Seeder For Sowing Non-Loose Seeds Of Saxaul And Cherkez, E.T. Farmonov Mar 2021

An Innovative Seeder For Sowing Non-Loose Seeds Of Saxaul And Cherkez, E.T. Farmonov

Irrigation and Melioration

The main reasons for the absence of a seeder for mechanized sowing of non-loose seeds of fodder plants in deserts are analyzed in the article. The author has developed a technology for sowing non-loose seeds (saxaul and cherkez), which prevents clogging, crushing and breakage in the seeder hopper, and provides for uniform and stable sowing at a set rate and shallow depth over the entire field area without reducing the biological germination. An innovative seeder with a universal sowing unit is recommended. Field tests of the innovative seeder with the proposed universal sowing unit were conducted in February 2020, as …

Go to article

Recommendations For The Analysis And Safety Assessment Of Turbid Sediments In Flood Reservoirs, А. Yangiev, Sh. Panjiev, D. Adjimuradov Mar 2021

Recommendations For The Analysis And Safety Assessment Of Turbid Sediments In Flood Reservoirs, А. Yangiev, Sh. Panjiev, D. Adjimuradov

Irrigation and Melioration

The article presents the results of field research conducted in Langar, Dehkanabad, Shurabsoy flood reservoirs in the Kashkadarya region.There are many problems as a result of floods in the reservoirs, there are disturbances in the discharge and drainage facilities during the passage of accidental floods.At the same time, there was a large accumulation of turbid-sediments in flood reservoirs.In the article, the results of the calculations using empirical formulas for predicting the amount of turbid sediments in Langar, Dehkanabad, Shurabsoy flood reservoirs up to 2025-2030 years are also presented, and it is noted that at present their useless volumes are full …

Go to article

Justification Of Parameters Of Replaceable Working Parts Of A Combined Machine, А.A. Akhmetov, L.B. Muratov Mar 2021

Justification Of Parameters Of Replaceable Working Parts Of A Combined Machine, А.A. Akhmetov, L.B. Muratov

Irrigation and Melioration

In article are described the design and options for completing the replaceable working parts of the combined machine for continuous tillage which of the formation of ridges and ridges for sowing re-crops. The parameters of the ridge former and apron-leveler of this machine have been substantiated. The rational values of the parameters of the comb-former are: length 600 mm, width of the entrance edge 680 mm, height of the blade 160 mm, length of the side edge of the blade 178 mm. The rational values of the working length and height of the leveling apron are 220 mm and 200 …

Go to article

Development Of An Algorithm For Optimization Of Continuous Technological Process Of Cultivation Of Microorganisms, Sh.R. Rakhmanov Mar 2021

Development Of An Algorithm For Optimization Of Continuous Technological Process Of Cultivation Of Microorganisms, Sh.R. Rakhmanov

Irrigation and Melioration

In article the analysis of possible modes of microalgae cultivation has been carried out. Two optimization algorithms are substantiated. The first one is based on the method of random search with an absolute bias, an algorithm for optimizing the process of cultivating microorganisms with continuous regeneration of the flow in one cultivator. The second is an algorithm for determining the optimal residence time of chlorella particles in multistage cultivators, focused on the method of dynamic programming, implemented in Wellman's recurrence relation. The developed algorithm for operational forecasting and automatic control of the chlorella cultivation process allows, under given production conditions …

Go to article

Covid-19 Impact To Family Food Consumption And Income In Uzbekistan: Results Of An Online Survey, Kh. Pardaev, Sh. Hasanov, S. Mamasoliev, Sh. Muratov, R. Kalandarov, U. Nurullaev Mar 2021

Covid-19 Impact To Family Food Consumption And Income In Uzbekistan: Results Of An Online Survey, Kh. Pardaev, Sh. Hasanov, S. Mamasoliev, Sh. Muratov, R. Kalandarov, U. Nurullaev

Irrigation and Melioration

This article aims to study the impact of the pandemic on food consumption by families in Uzbekistan. The shock of the pandemic is threatening the well-being of families in Uzbekistan, as in all developing countries. The study focuses on the effects of changes in food prices, declining consumption, and changes in household incomes. The Instrumental regression model was used in the factor impact analysis. Data for analysis were collected online by messenger groups from families in urban and rural areas of Uzbekistan. Results of the Econometric analysis demonstrated that the decline in food consumption in households was assessed by a …

Go to article

Status Of Crop Diversification And Its Empirical Analysis: A Case Study Of The Republic Of Uzbekistan, A.E. Primov Mar 2021

Status Of Crop Diversification And Its Empirical Analysis: A Case Study Of The Republic Of Uzbekistan, A.E. Primov

Irrigation and Melioration

The main objective of this study is to determine the status and level of crop diversification among farms in the country through an empirical analysis using panel data collected in 2009-2017. In doing so, we performed the Stata-16 software using the Simpson Diversification Index model in determining the diversification index. According to the results, the highest diversification indicators were found for Samarkand, Fergana and Tashkent regions, respectively, and accounted for 0.74, 0.74 and 0.76, respectively. It can be seen that the existing farms in Tashkent region used more diversified crops than in other regions of the country. The average diversification …

Go to article

Efficiency Of Using Graphic Software In The Design Of Hydrotechnical Structures, U.A. Nasritdinova, A.M. Khodjaev, Z.I. Kayumova Mar 2021

Efficiency Of Using Graphic Software In The Design Of Hydrotechnical Structures, U.A. Nasritdinova, A.M. Khodjaev, Z.I. Kayumova

Irrigation and Melioration

The article examines the work of scientists engaged in research in this area in the design of hydrotechnic structures. The possibilities of design programs for the application of the results of scientific research in the educational process were used. Thanks to the design in these programs, practical tasks are carried out with the utmost precision. The use of computer technology in teaching the subject "Hydrotechnical structures" and the use of graphic software AutoCAD in the design of linear platforms for clothing, curved platforms for clothing from hydrotechnical structures are shown in 2D and 3D three-dimensional modeling.

Go to article

Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Monemianesfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang Mar 2021

Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Monemianesfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang

Department of Mechanical and Materials Engineering: Faculty Publications

It is becoming increasingly clear that mechanical stress in adhesive junctions plays a significant role in dictating the fate of cell–cell attachment under physiological conditions. Targeted disruption of cell–cell junctions leads to multiple pathological conditions, among them the life-threatening autoimmune blistering disease pemphigus vulgaris (PV). The dissociation of cell–cell junctions by autoantibodies is the hallmark of PV, however, the detailed mechanisms that result in tissue destruction remain unclear. Thus far, research and therapy in PV have focused primarily on immune mechanisms upstream of autoantibody binding, while the biophysical aspects of the cell– cell dissociation process leading to acantholysis are less …

Go to article

Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Esfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang Mar 2021

Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Esfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang

Department of Mechanical and Materials Engineering: Faculty Publications

It is becoming increasingly clear that mechanical stress in adhesive junctions plays a significant role in dictating the fate of cell–cell attachment under physiological conditions. Targeted disruption of cell–cell junctions leads to multiple pathological conditions, among them the life-threatening autoimmune blistering disease pemphigus vulgaris (PV). The dissociation of cell–cell junctions by autoantibodies is the hallmark of PV, however, the detailed mechanisms that result in tissue destruction remain unclear. Thus far, research and therapy in PV have focused primarily on immune mechanisms upstream of autoantibody binding, while the biophysical aspects of the cell– cell dissociation process leading to acantholysis are less …

Go to article

Common Pool Resource Management: Assessing Water Resources Planning For Hydrologically Connected Surface And Groundwater Systems, Francisco Munoz-Arriola, Tarik Abdel-Monem, A. Amaranto Mar 2021

Common Pool Resource Management: Assessing Water Resources Planning For Hydrologically Connected Surface And Groundwater Systems, Francisco Munoz-Arriola, Tarik Abdel-Monem, A. Amaranto

Department of Mechanical and Materials Engineering: Faculty Publications

Common pool resource (CPR) management has the potential to overcome the collective action dilemma, defined as the tendency for individual users to exploit natural resources and contribute to a tragedy of the commons. Design principles associated with effective CPR management help to ensure that arrangements work to the mutual benefit of water users. This study contributes to current research on CPR management by examining the process of implementing integrated management planning through the lens of CPR design principles. Integrated management plans facilitate the management of a complex common pool resource, ground and surface water resources having a hydrological connection. Water …

Go to article

First Prev Next Last