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Articles 451 - 480 of 1721

Full-Text Articles in Engineering Science and Materials

High Throughput And Highly Controllable Methods For In Vitro Intracellular Delivery, Justin Brooks, Grayson Minnick, Prithvijit Mukherjee, Arian Jaberi, Lingqian Chang, Horacio D. Espinosa, Ruiguo Yang Dec 2022

High Throughput And Highly Controllable Methods For In Vitro Intracellular Delivery, Justin Brooks, Grayson Minnick, Prithvijit Mukherjee, Arian Jaberi, Lingqian Chang, Horacio D. Espinosa, Ruiguo Yang

Department of Mechanical and Materials Engineering: Faculty Publications

In vitro and ex vivo intracellular delivery methods hold the key for releasing the full potential of tissue engineering, drug development, and many other applications. In recent years, there has been significant progress in the design and implementation of intracellular delivery systems capable of delivery at the same scale as viral transfection and bulk electroporation but offering fewer adverse outcomes. This review strives to examine a variety of methods for in vitro and ex vivo intracellular delivery such as flow-through microfluidics, engineered substrates, and automated probe-based systems from the perspective of throughput and control. Special attention is paid to a …

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Backpack Effects On Two-Dimensional Gait Spatiotemporal And Kinematic Parameters, Nardo Rizaldy, Alvin Alvin, Wirawan Lingga, Ethan B.W. Goeij, F. Ferryanto Nov 2022

Backpack Effects On Two-Dimensional Gait Spatiotemporal And Kinematic Parameters, Nardo Rizaldy, Alvin Alvin, Wirawan Lingga, Ethan B.W. Goeij, F. Ferryanto

Journal of Mechanical Engineering Science and Technology (JMEST)

Loads could affect the body gait in various ways. Backpacks, sling bags, suitcases, and even trolleys could hugely affect human gait without us realizing it. The effects of these loads have been scientifically researched in biomechanics and sports science for the past few years. For instance, the comparison of walking with and without a backpack could easily reveal significant differences in body segments, which could be utilized for therapy and medicine development. The aim of this research is to determine the differences of the spatiotemporal kinematic parameters between a conventional human gait and a backpackloaded gait. Some parameters to be …

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Investigate The Potential Renewable Energy Of Microalgae Spirulina Sp Using Proximate Analyzer, Sem-Edx, And Thermogravimetry, Yahya Zakaria, Sukarni Sukarni, Poppy Puspitasari, Nandang Mufti, Samsudin Anis, Anwar Johari Nov 2022

Investigate The Potential Renewable Energy Of Microalgae Spirulina Sp Using Proximate Analyzer, Sem-Edx, And Thermogravimetry, Yahya Zakaria, Sukarni Sukarni, Poppy Puspitasari, Nandang Mufti, Samsudin Anis, Anwar Johari

Journal of Mechanical Engineering Science and Technology (JMEST)

Microalgae Spirulina sp which has been cultivated by the Brackishwater Aquaculture Development Center, Situbondo Indonesia were tested for their potential energy performance using proximate analyzer, SEMEDX, and thermogravimetry. The proximate analyzer showed volatile matter (VM), fixed carbon (FC), moisture, ash content (AC), total sulfur of microalgae Spirulina sp 68.15, 12.57, 11.22, 8.06, and 0.67 (wt%, ar), respectively, and the gross calorific value (GCV) is 4971 kcal/kg (dry basis). SEM-EDX test showed the morphology and chemical content of Spirulina sp. The content of microalgae Spirulina sp is dominated by carbon (C) and oxygen (O), then followed by chlorine (Cl), sodium (Na), …

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The Effect Of Nozzle Temperature, Infill Geometry, Layer Height And Fan Speed On Roughness Surface In Petg Filament, Doohan Taqdissillah, Aris Zainul Mutaqqin, Mahros Darsin, Dedi Dwilaksana, Nasrul Ilminnafik Nov 2022

The Effect Of Nozzle Temperature, Infill Geometry, Layer Height And Fan Speed On Roughness Surface In Petg Filament, Doohan Taqdissillah, Aris Zainul Mutaqqin, Mahros Darsin, Dedi Dwilaksana, Nasrul Ilminnafik

Journal of Mechanical Engineering Science and Technology (JMEST)

3D printing is a process of making three-dimensional solid objects from a digital file process created by laying down successive layers of material until the object is created. Many filaments can be used in 3D printing, one of which is PETG (PolyEthylene Terephthalate Glycol). PETG is a modification of PET (PolyEthylene Terephthalate) with added glycol at a molecular level to offer different chemical properties that provide significant chemical resistance, durability, and excellent formability for manufacturing. This study aims to find the most optimal parameter of surface roughness of PETG with different parameters of nozzle temperature, infill geometry, layer height and …

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Study On Predictive Maintenance Of V-Belt In Milling Machines Using Machine Learning, Reza Aulia Rahman, Mohammad Faishol Erikyatna, Achmad Fauzan Hery Soegiharto Nov 2022

Study On Predictive Maintenance Of V-Belt In Milling Machines Using Machine Learning, Reza Aulia Rahman, Mohammad Faishol Erikyatna, Achmad Fauzan Hery Soegiharto

Journal of Mechanical Engineering Science and Technology (JMEST)

Towards industry 4.0, monitoring the degradation of machine tools’ components becomes a key feature so that smooth productivity is achieved. To preserve the functionality and performance of the machine tools, proper maintenance activities must be planned and carried out. V-belt is important component in machine tools that transmits power from the electric motor spindle in order to machine to work and cut desired material properly. The purpose of this research is to develop a predictive maintenance system for v-belt milling machine Krisbow 31N2F using machine learning. The machine learning algorithm models using multiple and simple linear regression algorithm was developed …

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True Stress-Strain Behavior Of Al-Based Cast Automotive Alloy Under Different Ageing Conditions And The Effect Of Trace Zr, Mashiur Rahman Shoummo, Akib Abdullah Khan, Mohammad Salim Kaiser Nov 2022

True Stress-Strain Behavior Of Al-Based Cast Automotive Alloy Under Different Ageing Conditions And The Effect Of Trace Zr, Mashiur Rahman Shoummo, Akib Abdullah Khan, Mohammad Salim Kaiser

Journal of Mechanical Engineering Science and Technology (JMEST)

A thorough investigation has been carried out on the Al-12Si-1Mg-1Cu-1Ni automotive alloy considering different properties, specially mechanical properties associated with true stress and true strain with Zr addition of trace amount. A commercially available piston is melted to produce the alloy, and trace amount of Zr is added to make another. The base alloy along with the Zr added alloy had been applied to homogenization, solution treatment, quenching, and ageing in order to get the age-hardening response. The alloys have been heat-treated at 25 ºC, 200 ºC, and 300 ºC, respectively, for four hours for attaining the under, peak and …

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Effect Of Graphene Addition On Bacterial Cellulose-Based Nanocomposite, Jibril Maulana, Heru Suryanto, Aminnudin Aminnudin Nov 2022

Effect Of Graphene Addition On Bacterial Cellulose-Based Nanocomposite, Jibril Maulana, Heru Suryanto, Aminnudin Aminnudin

Journal of Mechanical Engineering Science and Technology (JMEST)

Bacterial cellulose (BC) is a widespread, low-cost biopolymer that has generally been produced from plants and biomass waste. A method for improving the range of applications for bacterial cellulose is adding graphene material. It has an outstanding feature that can increase the performance of nanocomposite materials. The research aims to observe the effect of graphene on the surface morphology, crystallinity, chemical bonding, and tensile strength of BC/CuO nanocomposite. For this study's synthesis, BC was synthesized by fermenting pineapple peel extract for 10 to 14 days. The produced BC was crushed, homogenized with a nano homogenizer machine, and filtered. Filtered BC, …

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Efects Of Non‑Newtonian Viscosity On Arterial And Venous Fow And Transport, Sabrina Lynch, Nitesh Nama, C Alberto Figueroa Nov 2022

Efects Of Non‑Newtonian Viscosity On Arterial And Venous Fow And Transport, Sabrina Lynch, Nitesh Nama, C Alberto Figueroa

Department of Mechanical and Materials Engineering: Faculty Publications

It is well known that blood exhibits non-Newtonian viscosity, but it is generally modeled as a Newtonian fluid. However, in situations of low shear rate, the validity of the Newtonian assumption is questionable. In this study, we investigated differences between Newtonian and non-Newtonian hemodynamic metrics such as velocity, vorticity, and wall shear stress. In addition, we investigated cardiovascular transport using two different approaches, Eulerian mass transport and Lagrangian particle tracking. Non-Newtonian solutions revealed important differences in both hemodynamic and transport metrics relative to the Newtonian model. Most notably for the hemodynamic metrics, in-plane velocity and vorticity were consistently larger in …

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Enhanced Electron Correlation And Significantly Suppressed Thermal Conductivity In Dirac Nodal-Line Metal Nanowires By Chemical Doping, Amanda L. Coughlin, Zhiliang Pan, Jeonghoon Hong, Tongxie Zhang, Xun Zhan, Wenqian Wu, Dongyue Xie, Tian Tong, Thomas Ruch, Jean J. Heremans, Jiming Bao, Herbert A. Fertig, Jian Wang, Jeongwoo Kim, Hanyu Zhu, Deyu Li, Shixiong Zhang Nov 2022

Enhanced Electron Correlation And Significantly Suppressed Thermal Conductivity In Dirac Nodal-Line Metal Nanowires By Chemical Doping, Amanda L. Coughlin, Zhiliang Pan, Jeonghoon Hong, Tongxie Zhang, Xun Zhan, Wenqian Wu, Dongyue Xie, Tian Tong, Thomas Ruch, Jean J. Heremans, Jiming Bao, Herbert A. Fertig, Jian Wang, Jeongwoo Kim, Hanyu Zhu, Deyu Li, Shixiong Zhang

Department of Mechanical and Materials Engineering: Faculty Publications

Enhancing electron correlation in a weakly interacting topological system has great potential to promote correlated topological states of matter with extraordinary quantum properties. Here, the enhancement of electron correlation in a prototypical topological metal, namely iridium dioxide (IrO2), via doping with 3d transition metal vanadium is demonstrated. Single-crystalline vanadium-doped IrO2 nanowires are synthesized through chemical vapor deposition where the nanowire yield and morphology are improved by creating rough surfaces on substrates. Vanadium doping leads to a dramatic decrease in Raman intensity without notable peak broadening, signifying the enhancement of electron correlation. The enhanced electron correlation is further …

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Exosomes Derived From Differentiated Human Admsc With The Schwann Cell Phenotype Modulate Peripheral Nerve-Related Cellular Functions, Bo Liu, Yunfan Kong, Wen Shi, Mitchell Kuss, Ke Liao, Guoku Hu, Peng Xiao, Jagadesan Sankarasubramanian, Chittibabu Guda, Xinglong Wang, Yuguo Lei, Bin Duan Nov 2022

Exosomes Derived From Differentiated Human Admsc With The Schwann Cell Phenotype Modulate Peripheral Nerve-Related Cellular Functions, Bo Liu, Yunfan Kong, Wen Shi, Mitchell Kuss, Ke Liao, Guoku Hu, Peng Xiao, Jagadesan Sankarasubramanian, Chittibabu Guda, Xinglong Wang, Yuguo Lei, Bin Duan

Department of Mechanical and Materials Engineering: Faculty Publications

Peripheral nerve regeneration remains a significant clinical challenge due to the unsatisfactory functional recovery and public health burden. Exosomes, especially those derived from mesenchymal stem cells (MSCs), are promising as potential cell-free therapeutics and gene therapy vehicles for promoting neural regeneration. In this study, we reported the differentiation of human adipose derived MSCs (hADMSCs) towards the Schwann cell (SC) phenotype (hADMSC-SCs) and then isolated exosomes from hADMSCs with and without differentiation (i.e., dExo vs uExo). We assessed and compared the effects of uExo and dExo on antioxidative, angiogenic, antiinflammatory, and axon growth promoting properties by using various peripheral nerve-related cells. …

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Designing And Cnc Machine Valve Sub-Plates And Quick Mounts For Hydraulic Power Training Systems, Connor Maxam Nov 2022

Designing And Cnc Machine Valve Sub-Plates And Quick Mounts For Hydraulic Power Training Systems, Connor Maxam

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Business and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Connor Maxam on November 22, 2022.

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Phase Space Analysis Of Nonlinear Wave Propagation In A Bistable Mechanical Metamaterial With A Defect, Mohammed A. Mohammed, Piyush Grover Nov 2022

Phase Space Analysis Of Nonlinear Wave Propagation In A Bistable Mechanical Metamaterial With A Defect, Mohammed A. Mohammed, Piyush Grover

Department of Mechanical and Materials Engineering: Faculty Publications

We study the dynamics of solitary waves traveling in a one-dimensional chain of bistable elements in the presence of a local inhomogeneity (“defect”). Numerical simulations reveal that depending upon its initial speed, an incoming solitary wave can get transmitted, captured, or reflected upon interaction with the defect. The dynamics are dominated by energy exchange between the wave and a breather mode localized at the defect. We derive a reduced-order two degree of freedom Hamiltonian model for wave-breather interaction and analyze it using dynamical systems techniques. Lobe dynamics analysis reveals the fine structure of phase space that leads to the complicated …

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Feedforward Control Of Thermal History In Laser Powder Bed Fusion: Toward Physics-Based Optimization Of Processing Parameters, Alex Riensche, Benjamin D. Bevans, Ziyad M. Smoqi, Reza Yavari, Ajay Krishnan, Josie Gilligan, Nicholas Piercy, Kevin D. Cole, Prahalada K. Rao Nov 2022

Feedforward Control Of Thermal History In Laser Powder Bed Fusion: Toward Physics-Based Optimization Of Processing Parameters, Alex Riensche, Benjamin D. Bevans, Ziyad M. Smoqi, Reza Yavari, Ajay Krishnan, Josie Gilligan, Nicholas Piercy, Kevin D. Cole, Prahalada K. Rao

Department of Mechanical and Materials Engineering: Faculty Publications

We developed and applied a model-driven feedforward control approach to mitigate thermal-induced flaw formation in laser powder bed fusion (LPBF) additive manufacturing process. The key idea was to avert heat buildup in a LPBF part before it is printed by adapting process parameters layer-by-layer based on insights from a physics-based thermal simulation model. The motivation being to replace cumbersome empirical build-and-test parameter optimization with a physics-guided strategy. The approach consisted of three steps: prediction, analysis, and correction. First, the temperature distribution of a part was predicted rapidly using a graph theory-based computational thermal model. Second, the model-derived thermal trends were …

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The Design And Manufacturing Of An Environmental Chamber To Test Microelectronic Devices, William Graber, Aniket Roy Chowdhury Nov 2022

The Design And Manufacturing Of An Environmental Chamber To Test Microelectronic Devices, William Graber, Aniket Roy Chowdhury

The Journal of Purdue Undergraduate Research

No abstract provided.

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A Method Of Assessing Peripheral Stent Abrasiveness Under Cyclic Deformations Experienced During Limb Movement, Courtney Keiser, Kaspars Maleckis, Pauline Struczewska, Majid Jadidi, Jason N. Mactaggart, Alexey Kamenskiy Nov 2022

A Method Of Assessing Peripheral Stent Abrasiveness Under Cyclic Deformations Experienced During Limb Movement, Courtney Keiser, Kaspars Maleckis, Pauline Struczewska, Majid Jadidi, Jason N. Mactaggart, Alexey Kamenskiy

Department of Mechanical and Materials Engineering: Faculty Publications

Poor outcomes of peripheral arterial disease stenting are often attributed to the inability of stents to accommodate the complex biomechanics of the flexed lower limb. Abrasion damage caused by rubbing of the stent against the artery wall during limb movement plays a significant role in reconstruction failure but has not been characterized. Our goals were to develop a method of assessing the abrasiveness of peripheral nitinol stents and apply it to several commercial devices. Misago, AbsolutePro, Innova, Zilver, SmartControl, SmartFlex, and Supera stents were deployed inside electrospun nanofibrillar tubes with femoropopliteal artery-mimicking mechanical properties and subjected to cyclic axial compression …

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Multi-Robot Symbolic Task And Motion Planning Leveraging Human Trust Models: Theory And Applications, Huanfei Zheng Nov 2022

Multi-Robot Symbolic Task And Motion Planning Leveraging Human Trust Models: Theory And Applications, Huanfei Zheng

All Dissertations

Multi-robot systems (MRS) can accomplish more complex tasks with two or more robots and have produced a broad set of applications. The presence of a human operator in an MRS can guarantee the safety of the task performing, but the human operators can be subject to heavier stress and cognitive workload in collaboration with the MRS than the single robot. It is significant for the MRS to have the provable correct task and motion planning solution for a complex task. That can reduce the human workload during supervising the task and improve the reliability of human-MRS collaboration. This dissertation relies …

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Revealing The Pulse-Induced Electroplasticity By Decoupling Electron Wind Force, Xing Li, Qi Zhu, Youran Hong, He Zheng, Jian Wang, Jiangwei Wang, Ze Zhang Oct 2022

Revealing The Pulse-Induced Electroplasticity By Decoupling Electron Wind Force, Xing Li, Qi Zhu, Youran Hong, He Zheng, Jian Wang, Jiangwei Wang, Ze Zhang

Department of Mechanical and Materials Engineering: Faculty Publications

Micro/nano electromechanical systems and nanodevices often suffer from degradation under electrical pulse. However, the origin of pulse-induced degradation remains an open question. Herein, we investigate the defect dynamics in Au nanocrystals under pulse conditions. By decoupling the electron wind force via a properly-designed in situ TEM electropulsing experiment, we reveal a non-directional migration of Σ3{112} incoherent twin boundary upon electropulsing, in contrast to the expected directional migration under electron wind force. Quantitative analyses demonstrate that such exceptional incoherent twin boundary migration is governed by the electron-dislocation interaction that enhances the atom vibration at dislocation cores, rather than driven by the …

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Highly Efficient, Perfect, Large Angular And Ultrawideband Solar Energy Absorber For Uv To Mir Range, Shobhit K. Patel, Arun Kumar Udayakumar, G. Mahendran, B. Vasudevan, Jaymit Surve, Juveriya Parmar Oct 2022

Highly Efficient, Perfect, Large Angular And Ultrawideband Solar Energy Absorber For Uv To Mir Range, Shobhit K. Patel, Arun Kumar Udayakumar, G. Mahendran, B. Vasudevan, Jaymit Surve, Juveriya Parmar

Department of Mechanical and Materials Engineering: Faculty Publications

Although different materials and designs have been tried in search of the ideal as well as ultrawideband light absorber, achieving ultra-broadband and robust unpolarized light absorption over a wide angular range has proven to be a major issue. Light-field regulation capabilities provided by optical metamaterials are a potential new technique for perfect absorbers. It is our goal to design and demonstrate an ultra-wideband solar absorber for the ultraviolet to a mid-infrared region that has an absorptivity of TE/TM light of 96.2% on average. In the visible, NIR, and MIR bands of the solar spectrum, the absorbed energy is determined to …

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Finite Element-Based Machine Learning Model For Predicting The Mechanical Properties Of Composite Hydrogels, Yasin Shokrollahi, Pengfei Dong, Peshala T. Gamage, Nashaita Patrawalla, Vipuil Kishore, Hozhabr Mozafari, Linxia Gu Oct 2022

Finite Element-Based Machine Learning Model For Predicting The Mechanical Properties Of Composite Hydrogels, Yasin Shokrollahi, Pengfei Dong, Peshala T. Gamage, Nashaita Patrawalla, Vipuil Kishore, Hozhabr Mozafari, Linxia Gu

Department of Mechanical and Materials Engineering: Faculty Publications

In this study, a finite element (FE)-based machine learning model was developed to predict the mechanical properties of bioglass (BG)-collagen (COL) composite hydrogels. Based on the experimental observation of BG-COL composite hydrogels with scanning electron microscope, 2000 microstructural images with randomly distributed BG particles were created. The BG particles have diameters ranging from 0.5 μm to 1.5 μm and a volume fraction from 17% to 59%. FE simulations of tensile testing were performed for calculating the Young’s modulus and Poisson’s ratio of 2000 microstructures. The microstructural images and the calculated Young’s modulus and Poisson’s ratio by FE simulation were used …

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Tuning The Mechanical Behavior Of Density-Graded Elastomeric Foam Structures Via Interlayer Properties., Kazi Z Uddin, Ibnaj A Anni, George Youssef, Behrad Koohbor Oct 2022

Tuning The Mechanical Behavior Of Density-Graded Elastomeric Foam Structures Via Interlayer Properties., Kazi Z Uddin, Ibnaj A Anni, George Youssef, Behrad Koohbor

Henry M. Rowan College of Engineering Departmental Research

The concept of density-graded foams has been proposed to simultaneously enhance strain energy dissipation and the load-bearing capacities at a reduced structural weight. From a practical perspective, the fabrication of density-graded foams is often achieved by stacking different foam densities. Under such conditions, the adhesive interlayer significantly affects the mechanical performance and failure modes of the structure. This work investigates the role of different adhesive layers on the mechanical and energy absorption behaviors of graded flexible foams with distinct density layers. Three adhesive candidates with different chemical, physical, and mechanical characteristics are used to assemble density-graded polyurea foam structures. The …

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Large Refrigerant Capacity In Superparamagnetic Iron Nanoparticles Embedded In A Thin Film Matrix, Kaushik Sarkar, Surabhi Shaji, Jeffrey E. Shield, Christian H. Binek, Dhananjay Kumar Oct 2022

Large Refrigerant Capacity In Superparamagnetic Iron Nanoparticles Embedded In A Thin Film Matrix, Kaushik Sarkar, Surabhi Shaji, Jeffrey E. Shield, Christian H. Binek, Dhananjay Kumar

Department of Mechanical and Materials Engineering: Faculty Publications

A magnetocaloric effect (MCE) with sizable isothermal entropy change (ΔS) maintained over a broad range of temperatures above the blocking temperature is reported for a rare earth-free superparamagnetic nanoparticle system comprising of Fe–TiN heterostructure. Superparamagnetic iron (Fe) particles were embedded in a titanium nitride (TiN) thin film matrix in a TiN/Fe/TiN multilayered pattern using a pulsed laser deposition method. High angle annular dark-field images in conjunction with dispersive energy analysis, recorded using scanning transmission electron microscopy, show a clear presence of alternating layers of Fe and TiN with a distinct atomic number contrast between Fe particles and TiN. Quantitative information …

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A Nanofiber-Embedded Microfluidic Platform For Studying Neurobiology, Donghee Lee, Navatha Shree Sharma, S. M. Shatil Shahriar, Kai Yang, Zheng Yan, Jingwei Xie Oct 2022

A Nanofiber-Embedded Microfluidic Platform For Studying Neurobiology, Donghee Lee, Navatha Shree Sharma, S. M. Shatil Shahriar, Kai Yang, Zheng Yan, Jingwei Xie

Department of Mechanical and Materials Engineering: Faculty Publications

Due to their biomimetic properties, electrospun nanofibers have been widely used in neurobiology studies. However, mechanistic understanding of cell-nanofiber interactions is challenging based on the current in vitro culture systems due to the lack of control of spatiotemporal patterning of cells and difficulty in monitoring single cell behavior. To overcome these issues, we apply microfluidic technology in combination with electrospun nanofibers for in vitro studies of interactions between neurons and nanofiber materials. We demonstrate a unique nanofiber embedded microfluidic device which contains patterned aligned or random electrospun nanofibers as a new culture system. With this device, we test how different …

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Preface For Millard Beatty, E. Baesu, Roger Fosdick Oct 2022

Preface For Millard Beatty, E. Baesu, Roger Fosdick

Department of Mechanical and Materials Engineering: Faculty Publications

Professor Beatty has contributed a wide variety of research papers and book articles on topics in finite elasticity, continuum mechanics and classical mechanics, including some fundamental experimental work. His works are clear and informative and expose a didactic quality. In the following, we briefly touch upon some of the highlights of his research involvement throughout the years.

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Impulse, Fall 2022, University Marketing And Communications, Jerome J. Lohr College Of Engineering Oct 2022

Impulse, Fall 2022, University Marketing And Communications, Jerome J. Lohr College Of Engineering

Impulse (Jerome J. Lohr College of Engineering Publication)

2 | Sanjeev Kumar Takes Helm as College’s 12th Dean
5 | College Develops Partnerships in India, Turkey
6 | Faculty News
8 | Aerofly — Profs, Alum Partner To Build Unique Drone
10 | Researchers Find Way to Extend Produce Shelf Life
12 | SDSU Claims National Title in Quarter-Scale Tractors
14 | Nation’s Top ASCE Chapter Housed at SDSU
16 | National Geo-Video Title Won By State Students
18 | Summer Brings Engineering Camps to Campus
20 | Haleigh Timmer — Money on the Court, In Classroom
22 | Daniel Burkhalter — Day in the Life of Student-Athlete …

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Me-Em Enewsbrief, September 2022, Department Of Mechanical Engineering-Engineering Mechanics, Michigan Technological University Oct 2022

Me-Em Enewsbrief, September 2022, Department Of Mechanical Engineering-Engineering Mechanics, Michigan Technological University

Department of Mechanical and Aerospace Engineering eNewsBrief

No abstract provided.

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Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farahnaz Fallahtafti, Mohammad Ali Takallou, Hafizur Rahman, Basheer Qolomany, Iraklis I. Pipinos, Fadi M. Alsaleem, Sara A. Myers Sep 2022

Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farahnaz Fallahtafti, Mohammad Ali Takallou, Hafizur Rahman, Basheer Qolomany, Iraklis I. Pipinos, Fadi M. Alsaleem, Sara A. Myers

Department of Mechanical and Materials Engineering: Faculty Publications

Peripheral artery disease (PAD) manifests from atherosclerosis, which limits blood flow to the legs and causes changes in muscle structure and function, and in gait performance. PAD is underdiagnosed, which delays treatment and worsens clinical outcomes. To overcome this challenge, the purpose of this study is to develop machine learning (ML) models that distinguish individuals with and without PAD. This is the first step to using ML to identify those with PAD risk early. We built ML models based on previously acquired overground walking biomechanics data from patients with PAD and healthy controls. Gait signatures were characterized using ankle, knee, …

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Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farahnaz Fallahtafti, Mohammad Ali Takallou, Basheer Qolomany, Iraklis I. Pipinos, Fadi Alsaleem, Sara A. Myers Sep 2022

Machine Learning-Based Peripheral Artery Disease Identification Using Laboratory-Based Gait Data, Ali Al-Ramini, Mahdi Hassan, Farahnaz Fallahtafti, Mohammad Ali Takallou, Basheer Qolomany, Iraklis I. Pipinos, Fadi Alsaleem, Sara A. Myers

Department of Mechanical and Materials Engineering: Faculty Publications

Peripheral artery disease (PAD) manifests from atherosclerosis, which limits blood flow to the legs and causes changes in muscle structure and function, and in gait performance. PAD is underdiagnosed, which delays treatment and worsens clinical outcomes. To overcome this challenge, the purpose of this study is to develop machine learning (ML) models that distinguish individuals with and without PAD. This is the first step to using ML to identify those with PAD risk early. We built ML models based on previously acquired overground walking biomechanics data from patients with PAD and healthy controls. Gait signatures were characterized using ankle, knee, …

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Design Of An Innovative Hybrid Sandwich Protective Device For Offshore Structures, Hozhabr Mozafari, Fabio Distefano, Gabriella Epasto, Linxia Gu, Emanoil Linul, Vincenzo Crupi Sep 2022

Design Of An Innovative Hybrid Sandwich Protective Device For Offshore Structures, Hozhabr Mozafari, Fabio Distefano, Gabriella Epasto, Linxia Gu, Emanoil Linul, Vincenzo Crupi

Department of Mechanical and Materials Engineering: Faculty Publications

Lightweight foam sandwich structures have excellent energy absorption capacity, combined with good mechanical properties and low density. The main goal of this study is to test the application of an innovative hybrid sandwich protective device in an offshore wind turbine (OWT). The results are useful for offshore structure applications. Different lightweight materials (aluminum foam, agglomerated cork, and polyurethane foam) were investigated using experimental tests and numerical simulations. Closed-cell aluminum foam showed the best performance in terms of the energy absorption capacity during an impact. As such, a Metallic Foam Shell (MFS) device was proposed for the fender of offshore wind …

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Spatially Guided Construction Of Multilayered Epidermal Models Recapturing Structural Hierarchy And Cell–Cell Junctions, Haiwei Zhai, Xiaowei Jin, Grayson Minnick, Jordan Rosenbohm, Mohammed Abdul Haleem Hafiz, Ruiguo Yang, Fanben Meng Sep 2022

Spatially Guided Construction Of Multilayered Epidermal Models Recapturing Structural Hierarchy And Cell–Cell Junctions, Haiwei Zhai, Xiaowei Jin, Grayson Minnick, Jordan Rosenbohm, Mohammed Abdul Haleem Hafiz, Ruiguo Yang, Fanben Meng

Department of Mechanical and Materials Engineering: Faculty Publications

A current challenge in 3D bioprinting of skin equivalents is to recreate the distinct basal and suprabasal layers and promote their direct interactions. Such a structural arrangement is essential to establish 3D stratified epidermis disease models, such as for the autoimmune skin disease pemphigus vulgaris (PV), which targets the cell– cell junctions at the interface of the basal and suprabasal layers. Inspired by epithelial regeneration in wound healing, a method that combines 3D bioprinting and spatially guided self-reorganization of keratinocytes is developed to recapture the fine structural hierarchy that lies in the deep layers of the epidermis.Herein, keratinocyteladen fibrin hydrogels …

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Biofilms: Formation, Research Models, Potential Targets, And Methods For Prevention And Treatment, Yajuan Su, Jaime T. Yrastorza, Mitchell Matis, Jenna Cusick, Siwei Zhao, Guangshun Wang, Jingwei Xie Aug 2022

Biofilms: Formation, Research Models, Potential Targets, And Methods For Prevention And Treatment, Yajuan Su, Jaime T. Yrastorza, Mitchell Matis, Jenna Cusick, Siwei Zhao, Guangshun Wang, Jingwei Xie

Department of Mechanical and Materials Engineering: Faculty Publications

Due to the continuous rise in biofilm-related infections, biofilms seriously threaten human health. The formation of biofilms makes conventional antibiotics ineffective and dampens immune clearance. Therefore, it is important to understand the mechanisms of biofilm formation and develop novel strategies to treat biofilms more effectively. This review article begins with an introduction to biofilm formation in various clinical scenarios and their corresponding therapy. Established biofilm models used in research are then summarized. The potential targets which may assist in the development of new strategies for combating biofilms are further discussed. The novel technologies developed recently for the prevention and treatment …

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