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Full-Text Articles in Nanotechnology Fabrication
Development Of A Lab-On-A-Chip Device For Rapid Nanotoxicity Assessment In Vitro, Pratikkumar Shah
Development Of A Lab-On-A-Chip Device For Rapid Nanotoxicity Assessment In Vitro, Pratikkumar Shah
FIU Electronic Theses and Dissertations
Increasing useof nanomaterials in consumer products and biomedical applications creates the possibilities of intentional/unintentional exposure to humans and the environment. Beyond the physiological limit, the nanomaterialexposure to humans can induce toxicity. It is difficult to define toxicity of nanoparticles on humans as it varies by nanomaterialcomposition, size, surface properties and the target organ/cell line. Traditional tests for nanomaterialtoxicity assessment are mostly based on bulk-colorimetric assays. In many studies, nanomaterials have found to interfere with assay-dye to produce false results and usually require several hours or days to collect results. Therefore, there is a clear need for alternative tools that can …
Bionano Electronics: Magneto-Electric Nanoparticles For Drug Delivery, Brain Stimulation And Imaging Applications, Rakesh Guduru
Bionano Electronics: Magneto-Electric Nanoparticles For Drug Delivery, Brain Stimulation And Imaging Applications, Rakesh Guduru
FIU Electronic Theses and Dissertations
Nanoparticles are often considered as efficient drug delivery vehicles for precisely dispensing the therapeutic payloads specifically to the diseased sites in the patient’s body, thereby minimizing the toxic side effects of the payloads on the healthy tissue. However, the fundamental physics that underlies the nanoparticles’ intrinsic interaction with the surrounding cells is inadequately elucidated. The ability of the nanoparticles to precisely control the release of its payloads externally (on-demand) without depending on the physiological conditions of the target sites has the potential to enable patient- and disease-specific nanomedicine, also known as Personalized NanoMedicine (PNM). In this dissertation, magneto-electric nanoparticles (MENs) …