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Tissue engineering

Mechanics of Materials

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Development Of A 3d Printed Conductive Biopolymer For Cardiac Tissue Engineering, Britanny Lizeth Stark Dec 2023

Development Of A 3d Printed Conductive Biopolymer For Cardiac Tissue Engineering, Britanny Lizeth Stark

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Cardiovascular disease (CVD) is the leading cause of death in the US, with approximately 859,000 deaths each year. The major contributor to CVD is Acute Myocardial Infarction (AMI), which causes the death of approximately 25% of the cardiomyocytes present in the left ventricle of the heart. After AMI, the adult human heart has a very limited regenerative capacity. Moreover, the electrical propagation of the myocardium is severely disrupted, making the heart more susceptible to failure and patient death. However, current pharmacological treatments do not address the loss of cardiomyocytes and the disruption of electrical propagation in the heart. Tissue engineering …